Reviews Zoladex 3.6


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Zoladex 3.6 Drug Description
Zoladex® 3.6 mg
(goserelin acetate) Implant
Equivalent to 3.6 mg goserelin
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 3.6 »




ZOLADEX® (goserelin acetate implant), contains a potent
synthetic decapeptide analogue of luteinizing hormone-releasing hormone (LHRH),
also known as a gonadotropin releasing hormone (GnRH) agonist analogue.
Goserelin acetate is chemically described as an acetate salt of [DSer (But)6,
Azgly10]LHRH. Its chemical structure is
pyro-Glu-His-Trp-Ser-Tyr-D-Ser (But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)
x where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular
weight of 1269 Daltons (free base). It is freely soluble in glacial acetic
acid. It is soluble in water, 0.1M hydrochloric acid, 0.1M sodium hydroxide,
dimethylformamide and dimethyl sulfoxide. Goserelin acetate is practically
insoluble in acetone, chloroform and ether.
ZOLADEX is supplied as a sterile, biodegradable product
containing goserelin acetate equivalent to 3.6 mg of goserelin. ZOLADEX is
designed for subcutaneous injection with continuous release over a 28-day
period. Goserelin acetate is dispersed in a matrix of D,L-lactic and glycolic
acids copolymer (13.3-14.3 mg/dose) containing less than 2.5% acetic acid and
up to 12% goserelin-related substances and presented as a sterile, white to
cream colored 1-mm diameter cylinder, preloaded in a special single use syringe
with a 16-gauge x 36 +/- 0.5 mm siliconized needle with protective needle sleeve
(SafeSystem™ Syringe) in a sealed, light and moisture proof, aluminum foil
laminate pouch containing a desiccant capsule. Studies of the D,L-lactic and
glycolic acids copolymer have indicated that it is completely biodegradable and
has no demonstrable antigenic potential.Last reviewed on RxList: 6/29/2009




Zoladex 3.6 Drug Description
Zoladex® 3.6 mg
(goserelin acetate) Implant
Equivalent to 3.6 mg goserelin
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 3.6 »




ZOLADEX® (goserelin acetate implant), contains a potent
synthetic decapeptide analogue of luteinizing hormone-releasing hormone (LHRH),
also known as a gonadotropin releasing hormone (GnRH) agonist analogue.
Goserelin acetate is chemically described as an acetate salt of [DSer (But)6,
Azgly10]LHRH. Its chemical structure is
pyro-Glu-His-Trp-Ser-Tyr-D-Ser (But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)
x where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular
weight of 1269 Daltons (free base). It is freely soluble in glacial acetic
acid. It is soluble in water, 0.1M hydrochloric acid, 0.1M sodium hydroxide,
dimethylformamide and dimethyl sulfoxide. Goserelin acetate is practically
insoluble in acetone, chloroform and ether.
ZOLADEX is supplied as a sterile, biodegradable product
containing goserelin acetate equivalent to 3.6 mg of goserelin. ZOLADEX is
designed for subcutaneous injection with continuous release over a 28-day
period. Goserelin acetate is dispersed in a matrix of D,L-lactic and glycolic
acids copolymer (13.3-14.3 mg/dose) containing less than 2.5% acetic acid and
up to 12% goserelin-related substances and presented as a sterile, white to
cream colored 1-mm diameter cylinder, preloaded in a special single use syringe
with a 16-gauge x 36 +/- 0.5 mm siliconized needle with protective needle sleeve
(SafeSystem™ Syringe) in a sealed, light and moisture proof, aluminum foil
laminate pouch containing a desiccant capsule. Studies of the D,L-lactic and
glycolic acids copolymer have indicated that it is completely biodegradable and
has no demonstrable antigenic potential.Last reviewed on RxList: 6/29/2009




Zoladex 3.6 Drug Description
Zoladex® 3.6 mg
(goserelin acetate) Implant
Equivalent to 3.6 mg goserelin
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 3.6 »




ZOLADEX® (goserelin acetate implant), contains a potent
synthetic decapeptide analogue of luteinizing hormone-releasing hormone (LHRH),
also known as a gonadotropin releasing hormone (GnRH) agonist analogue.
Goserelin acetate is chemically described as an acetate salt of [DSer (But)6,
Azgly10]LHRH. Its chemical structure is
pyro-Glu-His-Trp-Ser-Tyr-D-Ser (But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)
x where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular
weight of 1269 Daltons (free base). It is freely soluble in glacial acetic
acid. It is soluble in water, 0.1M hydrochloric acid, 0.1M sodium hydroxide,
dimethylformamide and dimethyl sulfoxide. Goserelin acetate is practically
insoluble in acetone, chloroform and ether.
ZOLADEX is supplied as a sterile, biodegradable product
containing goserelin acetate equivalent to 3.6 mg of goserelin. ZOLADEX is
designed for subcutaneous injection with continuous release over a 28-day
period. Goserelin acetate is dispersed in a matrix of D,L-lactic and glycolic
acids copolymer (13.3-14.3 mg/dose) containing less than 2.5% acetic acid and
up to 12% goserelin-related substances and presented as a sterile, white to
cream colored 1-mm diameter cylinder, preloaded in a special single use syringe
with a 16-gauge x 36 +/- 0.5 mm siliconized needle with protective needle sleeve
(SafeSystem™ Syringe) in a sealed, light and moisture proof, aluminum foil
laminate pouch containing a desiccant capsule. Studies of the D,L-lactic and
glycolic acids copolymer have indicated that it is completely biodegradable and
has no demonstrable antigenic potential.Last reviewed on RxList: 6/29/2009




Zoladex 3.6 Drug Description
Zoladex® 3.6 mg
(goserelin acetate) Implant
Equivalent to 3.6 mg goserelin
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 3.6 »




ZOLADEX® (goserelin acetate implant), contains a potent
synthetic decapeptide analogue of luteinizing hormone-releasing hormone (LHRH),
also known as a gonadotropin releasing hormone (GnRH) agonist analogue.
Goserelin acetate is chemically described as an acetate salt of [DSer (But)6,
Azgly10]LHRH. Its chemical structure is
pyro-Glu-His-Trp-Ser-Tyr-D-Ser (But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)
x where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular
weight of 1269 Daltons (free base). It is freely soluble in glacial acetic
acid. It is soluble in water, 0.1M hydrochloric acid, 0.1M sodium hydroxide,
dimethylformamide and dimethyl sulfoxide. Goserelin acetate is practically
insoluble in acetone, chloroform and ether.
ZOLADEX is supplied as a sterile, biodegradable product
containing goserelin acetate equivalent to 3.6 mg of goserelin. ZOLADEX is
designed for subcutaneous injection with continuous release over a 28-day
period. Goserelin acetate is dispersed in a matrix of D,L-lactic and glycolic
acids copolymer (13.3-14.3 mg/dose) containing less than 2.5% acetic acid and
up to 12% goserelin-related substances and presented as a sterile, white to
cream colored 1-mm diameter cylinder, preloaded in a special single use syringe
with a 16-gauge x 36 +/- 0.5 mm siliconized needle with protective needle sleeve
(SafeSystem™ Syringe) in a sealed, light and moisture proof, aluminum foil
laminate pouch containing a desiccant capsule. Studies of the D,L-lactic and
glycolic acids copolymer have indicated that it is completely biodegradable and
has no demonstrable antigenic potential.Last reviewed on RxList: 6/29/2009




Zoladex 3.6 Drug Description
Zoladex® 3.6 mg
(goserelin acetate) Implant
Equivalent to 3.6 mg goserelin
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 3.6 »




ZOLADEX® (goserelin acetate implant), contains a potent
synthetic decapeptide analogue of luteinizing hormone-releasing hormone (LHRH),
also known as a gonadotropin releasing hormone (GnRH) agonist analogue.
Goserelin acetate is chemically described as an acetate salt of [DSer (But)6,
Azgly10]LHRH. Its chemical structure is
pyro-Glu-His-Trp-Ser-Tyr-D-Ser (But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)
x where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular
weight of 1269 Daltons (free base). It is freely soluble in glacial acetic
acid. It is soluble in water, 0.1M hydrochloric acid, 0.1M sodium hydroxide,
dimethylformamide and dimethyl sulfoxide. Goserelin acetate is practically
insoluble in acetone, chloroform and ether.
ZOLADEX is supplied as a sterile, biodegradable product
containing goserelin acetate equivalent to 3.6 mg of goserelin. ZOLADEX is
designed for subcutaneous injection with continuous release over a 28-day
period. Goserelin acetate is dispersed in a matrix of D,L-lactic and glycolic
acids copolymer (13.3-14.3 mg/dose) containing less than 2.5% acetic acid and
up to 12% goserelin-related substances and presented as a sterile, white to
cream colored 1-mm diameter cylinder, preloaded in a special single use syringe
with a 16-gauge x 36 +/- 0.5 mm siliconized needle with protective needle sleeve
(SafeSystem™ Syringe) in a sealed, light and moisture proof, aluminum foil
laminate pouch containing a desiccant capsule. Studies of the D,L-lactic and
glycolic acids copolymer have indicated that it is completely biodegradable and
has no demonstrable antigenic potential.Last reviewed on RxList: 6/29/2009





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Other reviews about Zoladex 3.6 on web:

Learn about the prescription medication Zoladex 3.6 (Goserelin Acetate Implant), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Zoladex 3.6 (Goserelin Acetate Implant) Drug Information: Uses ...


The mean ( ± standard deviation) pharmacokinetic parameter estimates of Zoladex after administration of 3.6 mg depot for 2 months in males and females are presented in the ... Zoladex Official FDA information, side effects and uses.


ZOLADEX ® (goserelin acetate implant) 3.6 mg Initial U.S. Approval: 1989-----RECENT MAJOR CHANGES-----Warnings and Precautions ... ZOLADEX


In controlled studies of patients with advanced prostatic cancer comparing ZOLADEX 3.6 mg to orchiectomy, the long-term endocrine responses and objective responses were similar ... ZOLADEX (goserelin acetate implant) Information | Advanced ...


ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin acetate equivalent to 3.6 mg of goserelin designed for administration every 28 days. Zoladex 10.8 mg (Goserelin Acetate Implant) Drug Information: Uses ...


How Zoladex will be given. The Zoladex 3.6 mg Implant will be injected under the skin on your stomach every four weeks (28 days). This will be done by your doctor or nurse. Zoladex 3.6mg Implant - X-PIL


The once-a-month Zoladex 3.6 mg formulation was recently cleared by the FDA for the treatment of advanced breast cancer in premenopausal and perimenopausal women. Zoladex (10.8 mg goserelin acetate implant) - Drug information ...


Zoladex Injection Side Effects: The most common Zoladex side effects (incidence >5% in clinical trials) for ZOLADEX 3.6-mg depot: hot flashes (62%), sexual dysfunction (21% ... Zoladex Injection, Zoladex Injection Side Effects ...


1 Rev 12/03 SIC 64216-00 ZOLADEX (goserelin acetate implant) 3.6 MG Equivalent to 3.6 mg goserelin DESCRIPTION ZOLADEX® (goserelin acetate implant), contains a potent ... (goserelin acetate implant) 3.6 MG


Two controlled clinical trials using ZOLADEX 10.8 mg versus ZOLADEX 3.6 mg were conducted. During a comparative phase, patients were randomized to receive either a single 10.8 mg ... Zoladex 3-Month Official FDA information, side effects and uses.





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