Reviews Zalcitabine


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Hivid Drug Description
HIVID®
(zalcitabine) Tablets

WARNING
THE USE OF HIVID HAS BEEN ASSOCIATED WITH SIGNIFICANT CLINICAL ADVERSE REACTIONS,
SOME OF WHICH ARE POTENTIALLY FATAL. HIVID CAN CAUSE SEVERE PERIPHERAL NEUROPATHY
AND BECAUSE OF THIS SHOULD BE USED WITH EXTREME CAUTION IN PATIENTS WITH
PREEXISTING NEUROPATHY. HIVID MAY ALSO RARELY CAUSE PANCREATITIS AND PATIENTS
WHO DEVELOP ANY SYMPTOMS SUGGESTIVE OF PANCREATITIS WHILE USING HIVID SHOULD
HAVE THERAPY SUSPENDED IMMEDIATELY UNTIL THIS DIAGNOSIS IS EXCLUDED.
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS, INCLUDING FATAL
CASES, HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES
ALONE OR IN COMBINATION, INCLUDING HIVID (SEE WARNINGS).
IN ADDITION, RARE CASES OF HEPATIC FAILURE AND DEATH CONSIDERED POSSIBLY
RELATED TO UNDERLYING HEPATITIS B AND HIVID HAVE BEEN REPORTED (SEE WARNINGS
AND PRECAUTIONS).

DRUG DESCRIPTION



What are the possible side effects of zalcitabine (Hivid)?

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:

liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and...
Read All Potential Side Effects for Hivid »




HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine
(ddC)], a synthetic pyrimidine nucleoside analogue active against the human
immunodeficiency virus (HIV). HIVID is available as film-coated tablets for
oral administration in strengths of 0.375 mg and 0.750 mg. Each tablet also
contains the inactive ingredients lactose, microcrystalline cellulose, croscarmellose
sodium, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol,
and polysorbate 80 along with the following colorant system: 0.375 mg tablet
— synthetic brown, black, red and yellow iron oxides, and titanium dioxide;
0.750 mg tablet — synthetic black iron oxide and titanium dioxide. The chemical
name for zalcitabine is 4-amino-1-beta-D-2', 3'-dideoxyribofuranosyl-2-(1H)-pyrimidone
or 2',3'-dideoxycytidine with the molecular formula C9H13N3O3
and a molecular weight of 211.22. Zalcitabine has the following structural formula:








Zalcitabine is a white to off-white crystalline powder with an aqueous solubility of 76.4 mg/mL at 25°CLast reviewed on RxList: 1/30/2009




Hivid Drug Description
HIVID®
(zalcitabine) Tablets

WARNING
THE USE OF HIVID HAS BEEN ASSOCIATED WITH SIGNIFICANT CLINICAL ADVERSE REACTIONS,
SOME OF WHICH ARE POTENTIALLY FATAL. HIVID CAN CAUSE SEVERE PERIPHERAL NEUROPATHY
AND BECAUSE OF THIS SHOULD BE USED WITH EXTREME CAUTION IN PATIENTS WITH
PREEXISTING NEUROPATHY. HIVID MAY ALSO RARELY CAUSE PANCREATITIS AND PATIENTS
WHO DEVELOP ANY SYMPTOMS SUGGESTIVE OF PANCREATITIS WHILE USING HIVID SHOULD
HAVE THERAPY SUSPENDED IMMEDIATELY UNTIL THIS DIAGNOSIS IS EXCLUDED.
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS, INCLUDING FATAL
CASES, HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES
ALONE OR IN COMBINATION, INCLUDING HIVID (SEE WARNINGS).
IN ADDITION, RARE CASES OF HEPATIC FAILURE AND DEATH CONSIDERED POSSIBLY
RELATED TO UNDERLYING HEPATITIS B AND HIVID HAVE BEEN REPORTED (SEE WARNINGS
AND PRECAUTIONS).

DRUG DESCRIPTION



What are the possible side effects of zalcitabine (Hivid)?

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:

liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and...
Read All Potential Side Effects for Hivid »




HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine
(ddC)], a synthetic pyrimidine nucleoside analogue active against the human
immunodeficiency virus (HIV). HIVID is available as film-coated tablets for
oral administration in strengths of 0.375 mg and 0.750 mg. Each tablet also
contains the inactive ingredients lactose, microcrystalline cellulose, croscarmellose
sodium, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol,
and polysorbate 80 along with the following colorant system: 0.375 mg tablet
— synthetic brown, black, red and yellow iron oxides, and titanium dioxide;
0.750 mg tablet — synthetic black iron oxide and titanium dioxide. The chemical
name for zalcitabine is 4-amino-1-beta-D-2', 3'-dideoxyribofuranosyl-2-(1H)-pyrimidone
or 2',3'-dideoxycytidine with the molecular formula C9H13N3O3
and a molecular weight of 211.22. Zalcitabine has the following structural formula:








Zalcitabine is a white to off-white crystalline powder with an aqueous solubility of 76.4 mg/mL at 25°CLast reviewed on RxList: 1/30/2009




Hivid Drug Description
HIVID®
(zalcitabine) Tablets

WARNING
THE USE OF HIVID HAS BEEN ASSOCIATED WITH SIGNIFICANT CLINICAL ADVERSE REACTIONS,
SOME OF WHICH ARE POTENTIALLY FATAL. HIVID CAN CAUSE SEVERE PERIPHERAL NEUROPATHY
AND BECAUSE OF THIS SHOULD BE USED WITH EXTREME CAUTION IN PATIENTS WITH
PREEXISTING NEUROPATHY. HIVID MAY ALSO RARELY CAUSE PANCREATITIS AND PATIENTS
WHO DEVELOP ANY SYMPTOMS SUGGESTIVE OF PANCREATITIS WHILE USING HIVID SHOULD
HAVE THERAPY SUSPENDED IMMEDIATELY UNTIL THIS DIAGNOSIS IS EXCLUDED.
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS, INCLUDING FATAL
CASES, HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES
ALONE OR IN COMBINATION, INCLUDING HIVID (SEE WARNINGS).
IN ADDITION, RARE CASES OF HEPATIC FAILURE AND DEATH CONSIDERED POSSIBLY
RELATED TO UNDERLYING HEPATITIS B AND HIVID HAVE BEEN REPORTED (SEE WARNINGS
AND PRECAUTIONS).

DRUG DESCRIPTION



What are the possible side effects of zalcitabine (Hivid)?

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:

liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and...
Read All Potential Side Effects for Hivid »




HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine
(ddC)], a synthetic pyrimidine nucleoside analogue active against the human
immunodeficiency virus (HIV). HIVID is available as film-coated tablets for
oral administration in strengths of 0.375 mg and 0.750 mg. Each tablet also
contains the inactive ingredients lactose, microcrystalline cellulose, croscarmellose
sodium, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol,
and polysorbate 80 along with the following colorant system: 0.375 mg tablet
— synthetic brown, black, red and yellow iron oxides, and titanium dioxide;
0.750 mg tablet — synthetic black iron oxide and titanium dioxide. The chemical
name for zalcitabine is 4-amino-1-beta-D-2', 3'-dideoxyribofuranosyl-2-(1H)-pyrimidone
or 2',3'-dideoxycytidine with the molecular formula C9H13N3O3
and a molecular weight of 211.22. Zalcitabine has the following structural formula:








Zalcitabine is a white to off-white crystalline powder with an aqueous solubility of 76.4 mg/mL at 25°CLast reviewed on RxList: 1/30/2009




Hivid Drug Description
HIVID®
(zalcitabine) Tablets

WARNING
THE USE OF HIVID HAS BEEN ASSOCIATED WITH SIGNIFICANT CLINICAL ADVERSE REACTIONS,
SOME OF WHICH ARE POTENTIALLY FATAL. HIVID CAN CAUSE SEVERE PERIPHERAL NEUROPATHY
AND BECAUSE OF THIS SHOULD BE USED WITH EXTREME CAUTION IN PATIENTS WITH
PREEXISTING NEUROPATHY. HIVID MAY ALSO RARELY CAUSE PANCREATITIS AND PATIENTS
WHO DEVELOP ANY SYMPTOMS SUGGESTIVE OF PANCREATITIS WHILE USING HIVID SHOULD
HAVE THERAPY SUSPENDED IMMEDIATELY UNTIL THIS DIAGNOSIS IS EXCLUDED.
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS, INCLUDING FATAL
CASES, HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES
ALONE OR IN COMBINATION, INCLUDING HIVID (SEE WARNINGS).
IN ADDITION, RARE CASES OF HEPATIC FAILURE AND DEATH CONSIDERED POSSIBLY
RELATED TO UNDERLYING HEPATITIS B AND HIVID HAVE BEEN REPORTED (SEE WARNINGS
AND PRECAUTIONS).

DRUG DESCRIPTION



What are the possible side effects of zalcitabine (Hivid)?

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:

liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and...
Read All Potential Side Effects for Hivid »




HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine
(ddC)], a synthetic pyrimidine nucleoside analogue active against the human
immunodeficiency virus (HIV). HIVID is available as film-coated tablets for
oral administration in strengths of 0.375 mg and 0.750 mg. Each tablet also
contains the inactive ingredients lactose, microcrystalline cellulose, croscarmellose
sodium, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol,
and polysorbate 80 along with the following colorant system: 0.375 mg tablet
— synthetic brown, black, red and yellow iron oxides, and titanium dioxide;
0.750 mg tablet — synthetic black iron oxide and titanium dioxide. The chemical
name for zalcitabine is 4-amino-1-beta-D-2', 3'-dideoxyribofuranosyl-2-(1H)-pyrimidone
or 2',3'-dideoxycytidine with the molecular formula C9H13N3O3
and a molecular weight of 211.22. Zalcitabine has the following structural formula:








Zalcitabine is a white to off-white crystalline powder with an aqueous solubility of 76.4 mg/mL at 25°CLast reviewed on RxList: 1/30/2009




Hivid Drug Description
HIVID®
(zalcitabine) Tablets

WARNING
THE USE OF HIVID HAS BEEN ASSOCIATED WITH SIGNIFICANT CLINICAL ADVERSE REACTIONS,
SOME OF WHICH ARE POTENTIALLY FATAL. HIVID CAN CAUSE SEVERE PERIPHERAL NEUROPATHY
AND BECAUSE OF THIS SHOULD BE USED WITH EXTREME CAUTION IN PATIENTS WITH
PREEXISTING NEUROPATHY. HIVID MAY ALSO RARELY CAUSE PANCREATITIS AND PATIENTS
WHO DEVELOP ANY SYMPTOMS SUGGESTIVE OF PANCREATITIS WHILE USING HIVID SHOULD
HAVE THERAPY SUSPENDED IMMEDIATELY UNTIL THIS DIAGNOSIS IS EXCLUDED.
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS, INCLUDING FATAL
CASES, HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES
ALONE OR IN COMBINATION, INCLUDING HIVID (SEE WARNINGS).
IN ADDITION, RARE CASES OF HEPATIC FAILURE AND DEATH CONSIDERED POSSIBLY
RELATED TO UNDERLYING HEPATITIS B AND HIVID HAVE BEEN REPORTED (SEE WARNINGS
AND PRECAUTIONS).

DRUG DESCRIPTION



What are the possible side effects of zalcitabine (Hivid)?

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:

liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and...
Read All Potential Side Effects for Hivid »




HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine
(ddC)], a synthetic pyrimidine nucleoside analogue active against the human
immunodeficiency virus (HIV). HIVID is available as film-coated tablets for
oral administration in strengths of 0.375 mg and 0.750 mg. Each tablet also
contains the inactive ingredients lactose, microcrystalline cellulose, croscarmellose
sodium, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol,
and polysorbate 80 along with the following colorant system: 0.375 mg tablet
— synthetic brown, black, red and yellow iron oxides, and titanium dioxide;
0.750 mg tablet — synthetic black iron oxide and titanium dioxide. The chemical
name for zalcitabine is 4-amino-1-beta-D-2', 3'-dideoxyribofuranosyl-2-(1H)-pyrimidone
or 2',3'-dideoxycytidine with the molecular formula C9H13N3O3
and a molecular weight of 211.22. Zalcitabine has the following structural formula:








Zalcitabine is a white to off-white crystalline powder with an aqueous solubility of 76.4 mg/mL at 25°CLast reviewed on RxList: 1/30/2009





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Other reviews about Zalcitabine on web:

Zalcitabine (2'-3'-dideoxy cytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor (NARTI) sold under the trade name Hivid. Zalcitabine - Wikipedia, the free encyclopedia


Learn about the prescription medication Hivid (Zalcitabine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Hivid (Zalcitabine) Drug Information: Uses, Side Effects, Drug ...


All about Zalcitabine. View complete and up to date Zalcitabine information - part of the Drugs.com trusted medication database. Zalcitabine Facts and Comparisons at Drugs.com


Discontinuation: Roche Pharmaceuticals has discontinued the sale and distribution of zalcitabine tablets. The announcement was made in a "Dear Health Care Professional" letter ... Zalcitabine (Hivid)


zalcitabine ( ) n. See DDC . [ zal- (perhaps alteration of (de)s- , variant of DE- + AL(COHOL) , from the missing hydroxyl groups of cytidine) + zalcitabine: Definition from Answers.com


Learn about HIV: Doctor produced to inform and explain the latest HIV and AIDS therapies. zalcitabine - HIV: Health and Medical Information About HIV and ...


zalcitabine patient information. Detailed drug information for the consumer, includes dosage, zalcitabine side effects and more. zalcitabine consumer information from Drugs.com


zalcitabine /zal·ci·ta·bine/ (zal-si´tah-bēn) 2′3′-dideoxycytidine, an antiretroviral agent that inhibits the action of reverse transcriptase; used in the treatment of HIV ... zalcitabine - definition of zalcitabine in the Medical dictionary ...


Zalcitabine. Lifestyle, fitness & health information about Zalcitabine. Medications That Cause Neuropathy, What Drugs Do People With AIDS Take?, Diseases That Cause Neuropathy ... Zalcitabine | LIVESTRONG.COM


Consumer information about the medication ZALCITABINE (DDC) - ORAL (HIVID), includes side effects, drug interactions, recommended dosages, and storage information. Read more ... ZALCITABINE (DDC) - ORAL (HIVID) side effects, medical uses, and ...





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