Reviews Vorinostat


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Zolinza Drug Description
ZOLINZA™
(vorinostat) Capsules
DRUG DESCRIPTION



What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have any of these serious side effects:

sudden shortness of breath, chest pain that gets worse with breathing, coughing up blood, fainting;
pain or swelling in one or both legs;
pale skin, easy bruising or bleeding, unusual weakness;
black,...
Read All Potential Side Effects for Zolinza »




ZOLINZA contains vorinostat, which is described chemically as N-hydroxy-N'-phenyloctanediamide.
The empirical formula is C14H20N2O3.
The molecular weight is 264.32 and the structural formula is:








Vorinostat is a white to light orange powder. It is very
slightly soluble in water, slightly soluble in ethanol, isopropanol and
acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic. The differential
scanning calorimetry ranged from 161.7 (endotherm) to 163.9°C. The pH of
saturated water solutions of vorinostat drug substance was 6.6. The pKa of
vorinostat was determined to be 9.2.
Each 100 mg ZOLINZA capsule for oral administration contains
100 mg vorinostat and the following inactive ingredients: microcrystalline
cellulose, sodium croscarmellose and magnesium stearate. The capsule shell
excipients are titanium dioxide, gelatin and sodium lauryl sulfate.Last reviewed on RxList: 10/15/2009




Zolinza Drug Description
ZOLINZA™
(vorinostat) Capsules
DRUG DESCRIPTION



What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have any of these serious side effects:

sudden shortness of breath, chest pain that gets worse with breathing, coughing up blood, fainting;
pain or swelling in one or both legs;
pale skin, easy bruising or bleeding, unusual weakness;
black,...
Read All Potential Side Effects for Zolinza »




ZOLINZA contains vorinostat, which is described chemically as N-hydroxy-N'-phenyloctanediamide.
The empirical formula is C14H20N2O3.
The molecular weight is 264.32 and the structural formula is:








Vorinostat is a white to light orange powder. It is very
slightly soluble in water, slightly soluble in ethanol, isopropanol and
acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic. The differential
scanning calorimetry ranged from 161.7 (endotherm) to 163.9°C. The pH of
saturated water solutions of vorinostat drug substance was 6.6. The pKa of
vorinostat was determined to be 9.2.
Each 100 mg ZOLINZA capsule for oral administration contains
100 mg vorinostat and the following inactive ingredients: microcrystalline
cellulose, sodium croscarmellose and magnesium stearate. The capsule shell
excipients are titanium dioxide, gelatin and sodium lauryl sulfate.Last reviewed on RxList: 10/15/2009




Zolinza Drug Description
ZOLINZA™
(vorinostat) Capsules
DRUG DESCRIPTION



What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have any of these serious side effects:

sudden shortness of breath, chest pain that gets worse with breathing, coughing up blood, fainting;
pain or swelling in one or both legs;
pale skin, easy bruising or bleeding, unusual weakness;
black,...
Read All Potential Side Effects for Zolinza »




ZOLINZA contains vorinostat, which is described chemically as N-hydroxy-N'-phenyloctanediamide.
The empirical formula is C14H20N2O3.
The molecular weight is 264.32 and the structural formula is:








Vorinostat is a white to light orange powder. It is very
slightly soluble in water, slightly soluble in ethanol, isopropanol and
acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic. The differential
scanning calorimetry ranged from 161.7 (endotherm) to 163.9°C. The pH of
saturated water solutions of vorinostat drug substance was 6.6. The pKa of
vorinostat was determined to be 9.2.
Each 100 mg ZOLINZA capsule for oral administration contains
100 mg vorinostat and the following inactive ingredients: microcrystalline
cellulose, sodium croscarmellose and magnesium stearate. The capsule shell
excipients are titanium dioxide, gelatin and sodium lauryl sulfate.Last reviewed on RxList: 10/15/2009




Zolinza Drug Description
ZOLINZA™
(vorinostat) Capsules
DRUG DESCRIPTION



What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have any of these serious side effects:

sudden shortness of breath, chest pain that gets worse with breathing, coughing up blood, fainting;
pain or swelling in one or both legs;
pale skin, easy bruising or bleeding, unusual weakness;
black,...
Read All Potential Side Effects for Zolinza »




ZOLINZA contains vorinostat, which is described chemically as N-hydroxy-N'-phenyloctanediamide.
The empirical formula is C14H20N2O3.
The molecular weight is 264.32 and the structural formula is:








Vorinostat is a white to light orange powder. It is very
slightly soluble in water, slightly soluble in ethanol, isopropanol and
acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic. The differential
scanning calorimetry ranged from 161.7 (endotherm) to 163.9°C. The pH of
saturated water solutions of vorinostat drug substance was 6.6. The pKa of
vorinostat was determined to be 9.2.
Each 100 mg ZOLINZA capsule for oral administration contains
100 mg vorinostat and the following inactive ingredients: microcrystalline
cellulose, sodium croscarmellose and magnesium stearate. The capsule shell
excipients are titanium dioxide, gelatin and sodium lauryl sulfate.Last reviewed on RxList: 10/15/2009




Zolinza Drug Description
ZOLINZA™
(vorinostat) Capsules
DRUG DESCRIPTION



What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using vorinostat and call your doctor at once if you have any of these serious side effects:

sudden shortness of breath, chest pain that gets worse with breathing, coughing up blood, fainting;
pain or swelling in one or both legs;
pale skin, easy bruising or bleeding, unusual weakness;
black,...
Read All Potential Side Effects for Zolinza »




ZOLINZA contains vorinostat, which is described chemically as N-hydroxy-N'-phenyloctanediamide.
The empirical formula is C14H20N2O3.
The molecular weight is 264.32 and the structural formula is:








Vorinostat is a white to light orange powder. It is very
slightly soluble in water, slightly soluble in ethanol, isopropanol and
acetone, freely soluble in dimethyl sulfoxide and insoluble in methylene chloride. It has no chiral centers and is non-hygroscopic. The differential
scanning calorimetry ranged from 161.7 (endotherm) to 163.9°C. The pH of
saturated water solutions of vorinostat drug substance was 6.6. The pKa of
vorinostat was determined to be 9.2.
Each 100 mg ZOLINZA capsule for oral administration contains
100 mg vorinostat and the following inactive ingredients: microcrystalline
cellulose, sodium croscarmellose and magnesium stearate. The capsule shell
excipients are titanium dioxide, gelatin and sodium lauryl sulfate.Last reviewed on RxList: 10/15/2009





Other reviews about Vorinostat on wordpress

A real histone deacetylase inhibitor finally approved for cancer
  by David
SAHA, or suberoylanilide hydroxamic acid, was recently granted orphan drug approval by the US FDA for skin lesions resulting from cutaneous T-cell lymphoma. SAHA (vorinostat, Zolinza) will be marketed […]


Other New Advances in Drug Therapies for Cancer
  by heremias
Individuals with cancer and family members often want to know that there are new drugs being developed and approved for all types of cancer. All drugs used for […]


NCI features another natural product in clinical trials
  by David
Today's edition of the NCI Cancer Bulletin features another natural product clinical trial, this time for depsipeptide in T-cell lymphoma. Depsipeptide (Romidepsin or FR901228) is an early histone deacetylase […]


Mesothelioma clinical trial underway for Vorinostat
  by John Caron
[…]


Merck wants a hustle pertinent to bottomless purse overfull
  by harmonymacella
Merck is lengthening its closeness means of access the oncology quadrangle and self-discipline co-mellow and commercialise Ariad Pharmaceuticals’ belated-range mold connection on a bang that could be there […]


Merck wants a hustle pertinent to bottomless purse overfull
  by harmonymacella
Merck is lengthening its closeness means of access the oncology quadrangle and self-discipline co-mellow and commercialise Ariad Pharmaceuticals’ belated-range mold connection on a bang that could be there […]


Merck wants a pail anent wherewithal immoderately
  by aikoalfrednpa
Merck is swelling its face within the oncology technology and need co-bring out and commercialise Ariad Pharmaceuticals’ checked-field carcinoma legal counselor chic a film that could have being […]


Merck wants a pail anent wherewithal immoderately
  by aikoalfrednpa
Merck is swelling its face within the oncology technology and need co-bring out and commercialise Ariad Pharmaceuticals’ checked-field carcinoma legal counselor chic a film that could have being […]


Merck Sharp & Dohme Ltd Withdraws Its Marketing Authorisation Application For Vorinostat MSD (vorinostat)
  by enartion
The European Medicines Agency (EMEA) has been formally notified by Merck Sharp & Dohme Ltd of its decision to withdraw its application for a centralised marketing authorisation for […]



Other reviews about Vorinostat on web:

Vorinostat or suberoyl anilide hydroxamic acid (SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a ... Vorinostat - Wikipedia, the free encyclopedia


This page contains brief information about vorinostat and a collection of links to more information about the use of this drug, related news, and ongoing clinical trials. Vorinostat - National Cancer Institute


Vorinostat Brand names: Zolinza® Drug Forms: Vorinostat Capsules (below) Vorinostat Oral capsule Español: Vorinostat, Cápsula oral Vorinostat Vorinostat: Information from Answers.com


Print Chemotherapy Drugs Vorinostat (vor-IN-o-stat) Trade Name: Zolinza. Drug Type: Vorinostat is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Vorinostat Chemotherapy Drugs and Side Effects


All about Vorinostat. View complete and up to date Vorinostat information - part of the Drugs.com trusted medication database. Vorinostat Facts and Comparisons at Drugs.com


Learn more about Vorinostat. Find the Web's best health guides, medical reports, news, videos and tools for Vorinostat. Share Vorinostat experiences and get advice from experts. Vorinostat Overview - References, Advice, News, Videos, Coping ...


Physician reviewed vorinostat patient information - includes vorinostat description, dosage and directions. vorinostat medical facts from Drugs.com


Features information about dosage, usage, warnings, and side effects. Vorinostat: MedlinePlus Drug Information


Vorinostat is an anticancer medication indicated for the treatment of skin cancers, specifically cutaneous T-cell lymphoma. It is available as 100 mg white capsules manufactured by ... Vorinostat - Kosmix : Reference, Videos, Images, News, Shopping ...


Vorinostat is a prescription drug used to treat cutaneous T cell lymphoma (CTCL). CTCL is a cancer that affects the skin. It is a rare disease; approximately four new cases are ... Vorinostat - Medpedia





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