Reviews Vinblastine Sulfate


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Vinblastine Sulfate Drug Description
VinBLAStine Sulfate for Injection USP

WARNING
Caution – This preparation should be administered by individuals experienced in the administration of vinblastine sulfate. It is extremely important that the intravenous needle or catheter be properly positioned before any vinblastine sulfate is injected. Leakage into surrounding tissue during intravenous administration of vinblastine sulfate may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis.
FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.
See WARNINGS for the treatment of patients given intrathecal vinblastine.

DRUG DESCRIPTION
Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1)
(salt). It is the salt of an alkaloid extracted from Vinca rosea Linn.,
a common flowering herb known as the periwinkle (more properly known as Catharanthus
roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated
VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with
this preparation, growing cells are arrested in metaphase.
Chemical and physical evidence indicates that vinblastine sulfate has the molecular
formula C46H58O9N4•H2SO4
and that it is a dimeric alkaloid containing both indole and dihydroindole moieties.
The structural formula is as follows:







M.W.= 909.07
Vinblastine sulfate is a white to off-white powder. It is freely soluble in
water, soluble in methanol, and slightly soluble in ethanol. It is insoluble
in benzene, ether, and naphtha.
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.
Last reviewed on RxList: 1/13/2009




Vinblastine Sulfate Drug Description
VinBLAStine Sulfate for Injection USP

WARNING
Caution – This preparation should be administered by individuals experienced in the administration of vinblastine sulfate. It is extremely important that the intravenous needle or catheter be properly positioned before any vinblastine sulfate is injected. Leakage into surrounding tissue during intravenous administration of vinblastine sulfate may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis.
FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.
See WARNINGS for the treatment of patients given intrathecal vinblastine.

DRUG DESCRIPTION
Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1)
(salt). It is the salt of an alkaloid extracted from Vinca rosea Linn.,
a common flowering herb known as the periwinkle (more properly known as Catharanthus
roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated
VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with
this preparation, growing cells are arrested in metaphase.
Chemical and physical evidence indicates that vinblastine sulfate has the molecular
formula C46H58O9N4•H2SO4
and that it is a dimeric alkaloid containing both indole and dihydroindole moieties.
The structural formula is as follows:







M.W.= 909.07
Vinblastine sulfate is a white to off-white powder. It is freely soluble in
water, soluble in methanol, and slightly soluble in ethanol. It is insoluble
in benzene, ether, and naphtha.
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.
Last reviewed on RxList: 1/13/2009




Vinblastine Sulfate Drug Description
VinBLAStine Sulfate for Injection USP

WARNING
Caution – This preparation should be administered by individuals experienced in the administration of vinblastine sulfate. It is extremely important that the intravenous needle or catheter be properly positioned before any vinblastine sulfate is injected. Leakage into surrounding tissue during intravenous administration of vinblastine sulfate may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis.
FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.
See WARNINGS for the treatment of patients given intrathecal vinblastine.

DRUG DESCRIPTION
Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1)
(salt). It is the salt of an alkaloid extracted from Vinca rosea Linn.,
a common flowering herb known as the periwinkle (more properly known as Catharanthus
roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated
VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with
this preparation, growing cells are arrested in metaphase.
Chemical and physical evidence indicates that vinblastine sulfate has the molecular
formula C46H58O9N4•H2SO4
and that it is a dimeric alkaloid containing both indole and dihydroindole moieties.
The structural formula is as follows:







M.W.= 909.07
Vinblastine sulfate is a white to off-white powder. It is freely soluble in
water, soluble in methanol, and slightly soluble in ethanol. It is insoluble
in benzene, ether, and naphtha.
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.
Last reviewed on RxList: 1/13/2009




Vinblastine Sulfate Drug Description
VinBLAStine Sulfate for Injection USP

WARNING
Caution – This preparation should be administered by individuals experienced in the administration of vinblastine sulfate. It is extremely important that the intravenous needle or catheter be properly positioned before any vinblastine sulfate is injected. Leakage into surrounding tissue during intravenous administration of vinblastine sulfate may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis.
FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.
See WARNINGS for the treatment of patients given intrathecal vinblastine.

DRUG DESCRIPTION
Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1)
(salt). It is the salt of an alkaloid extracted from Vinca rosea Linn.,
a common flowering herb known as the periwinkle (more properly known as Catharanthus
roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated
VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with
this preparation, growing cells are arrested in metaphase.
Chemical and physical evidence indicates that vinblastine sulfate has the molecular
formula C46H58O9N4•H2SO4
and that it is a dimeric alkaloid containing both indole and dihydroindole moieties.
The structural formula is as follows:







M.W.= 909.07
Vinblastine sulfate is a white to off-white powder. It is freely soluble in
water, soluble in methanol, and slightly soluble in ethanol. It is insoluble
in benzene, ether, and naphtha.
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.
Last reviewed on RxList: 1/13/2009




Vinblastine Sulfate Drug Description
VinBLAStine Sulfate for Injection USP

WARNING
Caution – This preparation should be administered by individuals experienced in the administration of vinblastine sulfate. It is extremely important that the intravenous needle or catheter be properly positioned before any vinblastine sulfate is injected. Leakage into surrounding tissue during intravenous administration of vinblastine sulfate may cause considerable irritation. If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis.
FATAL IF GIVEN INTRATHECALLY. FOR INTRAVENOUS USE ONLY.
See WARNINGS for the treatment of patients given intrathecal vinblastine.

DRUG DESCRIPTION
Vinblastine Sulfate for Injection USP is vincaleukoblastine, sulfate (1:1)
(salt). It is the salt of an alkaloid extracted from Vinca rosea Linn.,
a common flowering herb known as the periwinkle (more properly known as Catharanthus
roseus G. Don). Previously, the generic name was vincaleukoblastine, abbreviated
VLB. It is a stathmokinetic oncolytic agent. When treated in vitro with
this preparation, growing cells are arrested in metaphase.
Chemical and physical evidence indicates that vinblastine sulfate has the molecular
formula C46H58O9N4•H2SO4
and that it is a dimeric alkaloid containing both indole and dihydroindole moieties.
The structural formula is as follows:







M.W.= 909.07
Vinblastine sulfate is a white to off-white powder. It is freely soluble in
water, soluble in methanol, and slightly soluble in ethanol. It is insoluble
in benzene, ether, and naphtha.
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Vinblastine Sulfate for Injection USP contain 10 mg (0.011 mmol) of vinblastine sulfate, in the form of a white, amorphous, solid lyophilized plug, without excipients. After reconstitution with sodium chloride solution, the pH of the resulting solution lies in the range of 3.5 to 5.
Last reviewed on RxList: 1/13/2009





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Other reviews about Vinblastine Sulfate on web:

Learn about the prescription medication Vinblastine Sulfate (Vinblastine Sulfate Injection), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Vinblastine Sulfate (Vinblastine Sulfate Injection) Drug ...


Vinblastine Sulfate professional patient advice. Specific and up to date information about Vinblastine Sulfate. Complete Vinblastine Sulfate information from Drugs.com


Vinblastine is an antimicrotubule drug used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer, breast cancer, head and neck cancer, and ... Vinblastine - Wikipedia, the free encyclopedia


Vinblastine Sulfate is an anti-cancer chemotherapy drug. VLB, Vinblastine Sulfate and Vincaleukoblastine are other names for Vinblastine. This medication is classified as a plant ... Vinblastine Sulfate, Vinblastine, Velban - Chemotherapy Drugs ...


vinblastine sulfate: product identification. cas no. 143-67-9 . einecs no. 205-606-0: formula VINBLASTINE SULFATE


View and buy high purity Vinblastine sulfate from Tocris Bioscience, the leading worldwide supplier of high performance life science reagents Vinblastine sulfate | [CAS 143-67-9] | Tocris Bioscience


Common Name: Vinblastine Sulfate for Injection EC Number: 2056-06-0 Chemical Name: Vincaleukoblastine, sulfate (1:1) (salt) Synonym(s): 039745 Formulation; VLB Formulation; Vinblastina ... Section 1 - Chemical Product and Company


Important Note: The Following Information Is Intended To Supplement, Not Substitute For, The Expertise And Judgment Of Your Physician, Pharmacist Or Other Healthcare Professional. VINBLASTINE SULFATE Patient Assistance Program


AHFS Detailed Monograph from Medscape Drug Reference ... Monograph - Vinblastine Sulfate. Class: ANTINEOPLASTIC AGENTS(10:00) - See Related General Statement Vinblastine IV: AHFS Detailed Monograph


Revised: 01 Mar 2008. SYNONYM(S): VBL, 1 Vincaleukoblastine Sulfate, 2 VLB 2. COMMON TRADE NAME(S): Vinblastine Sulfate Injection . CLASSIFICATION: mitotic inhibitor, 1 cytotoxic 3 Vinblastine : BC Cancer Agency





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