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Valcyte Drug Description
Valcyte
(valganciclovir hydrochloride) Tablets
Valcyte
(valganciclovir hydrochloride) for Oral Solution

WARNING
HEMATOLOGIC TOXICITY, CARCINOGENICITY, TERATOGENICITY, AND IMPAIRMENT OF
FERTILITY

Clinical toxicity of Valcyte, which is metabolized to ganciclovir, includes
granulocytopenia, anemia, and thrombocytopenia [see WARNINGS AND PRECAUTIONS].
In animal studies, ganciclovir was carcinogenic, teratogenic, and caused
aspermatogenesis [see WARNINGS AND PRECAUTIONS].


DRUG DESCRIPTION



What are the possible side effects of valganciclovir (Valcyte)?

Stop taking valganciclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
easy bruising, unusual bleeding;
numbness or tingling in a part of the body;
signs of infection (fever, chills, body aches, flu symptoms); or
seizure...
Read All Potential Side Effects for Valcyte »




Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride
salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers.
Ganciclovir is a synthetic guanine derivative active against CMV.
Valcyte is available as a 450 mg tablet for oral administration. Each tablet
contains 496.3 mg of valganciclovir HCl (corresponding to 450 mg of valganciclovir),
and the inactive ingredients microcrystalline cellulose, povidone K-30, crospovidone
and stearic acid. The film-coat applied to the tablets contains Opadry Pink®.
Valcyte is also available as a powder for oral solution, which when constituted
with water as directed contains 50 mg/mL valganciclovir free base. The inactive
ingredients of Valcyte for oral solution are sodium benzoate, fumaric acid,
povidone K-30, sodium saccharin, mannitol and tutti-frutti flavoring.
Valganciclovir HCl is a white to off-white crystalline powder with a molecular
formula of C14H22N6O5路HCl and a
molecular weight of 390.83. The chemical name for valganciclovir HCl is L-Valine,
2[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride.
Valganciclovir HCl is a polar hydrophilic compound with a solubility of 70 mg/mL
in water at 25°C at a pH of 7.0 and an n-octanol/water partition coefficient
of 0.0095 at pH 7.0. The pKa for valganciclovir HCl is 7.6.
The chemical structure of valganciclovir HCl is:








All doses in this insert are specified in terms of valganciclovir.
Last reviewed on RxList: 9/8/2010




Valcyte Drug Description
Valcyte
(valganciclovir hydrochloride) Tablets
Valcyte
(valganciclovir hydrochloride) for Oral Solution

WARNING
HEMATOLOGIC TOXICITY, CARCINOGENICITY, TERATOGENICITY, AND IMPAIRMENT OF
FERTILITY

Clinical toxicity of Valcyte, which is metabolized to ganciclovir, includes
granulocytopenia, anemia, and thrombocytopenia [see WARNINGS AND PRECAUTIONS].
In animal studies, ganciclovir was carcinogenic, teratogenic, and caused
aspermatogenesis [see WARNINGS AND PRECAUTIONS].


DRUG DESCRIPTION



What are the possible side effects of valganciclovir (Valcyte)?

Stop taking valganciclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
easy bruising, unusual bleeding;
numbness or tingling in a part of the body;
signs of infection (fever, chills, body aches, flu symptoms); or
seizure...
Read All Potential Side Effects for Valcyte »




Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride
salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers.
Ganciclovir is a synthetic guanine derivative active against CMV.
Valcyte is available as a 450 mg tablet for oral administration. Each tablet
contains 496.3 mg of valganciclovir HCl (corresponding to 450 mg of valganciclovir),
and the inactive ingredients microcrystalline cellulose, povidone K-30, crospovidone
and stearic acid. The film-coat applied to the tablets contains Opadry Pink®.
Valcyte is also available as a powder for oral solution, which when constituted
with water as directed contains 50 mg/mL valganciclovir free base. The inactive
ingredients of Valcyte for oral solution are sodium benzoate, fumaric acid,
povidone K-30, sodium saccharin, mannitol and tutti-frutti flavoring.
Valganciclovir HCl is a white to off-white crystalline powder with a molecular
formula of C14H22N6O5路HCl and a
molecular weight of 390.83. The chemical name for valganciclovir HCl is L-Valine,
2[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride.
Valganciclovir HCl is a polar hydrophilic compound with a solubility of 70 mg/mL
in water at 25°C at a pH of 7.0 and an n-octanol/water partition coefficient
of 0.0095 at pH 7.0. The pKa for valganciclovir HCl is 7.6.
The chemical structure of valganciclovir HCl is:








All doses in this insert are specified in terms of valganciclovir.
Last reviewed on RxList: 9/8/2010




Valcyte Drug Description
Valcyte
(valganciclovir hydrochloride) Tablets
Valcyte
(valganciclovir hydrochloride) for Oral Solution

WARNING
HEMATOLOGIC TOXICITY, CARCINOGENICITY, TERATOGENICITY, AND IMPAIRMENT OF
FERTILITY

Clinical toxicity of Valcyte, which is metabolized to ganciclovir, includes
granulocytopenia, anemia, and thrombocytopenia [see WARNINGS AND PRECAUTIONS].
In animal studies, ganciclovir was carcinogenic, teratogenic, and caused
aspermatogenesis [see WARNINGS AND PRECAUTIONS].


DRUG DESCRIPTION



What are the possible side effects of valganciclovir (Valcyte)?

Stop taking valganciclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
easy bruising, unusual bleeding;
numbness or tingling in a part of the body;
signs of infection (fever, chills, body aches, flu symptoms); or
seizure...
Read All Potential Side Effects for Valcyte »




Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride
salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers.
Ganciclovir is a synthetic guanine derivative active against CMV.
Valcyte is available as a 450 mg tablet for oral administration. Each tablet
contains 496.3 mg of valganciclovir HCl (corresponding to 450 mg of valganciclovir),
and the inactive ingredients microcrystalline cellulose, povidone K-30, crospovidone
and stearic acid. The film-coat applied to the tablets contains Opadry Pink®.
Valcyte is also available as a powder for oral solution, which when constituted
with water as directed contains 50 mg/mL valganciclovir free base. The inactive
ingredients of Valcyte for oral solution are sodium benzoate, fumaric acid,
povidone K-30, sodium saccharin, mannitol and tutti-frutti flavoring.
Valganciclovir HCl is a white to off-white crystalline powder with a molecular
formula of C14H22N6O5路HCl and a
molecular weight of 390.83. The chemical name for valganciclovir HCl is L-Valine,
2[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride.
Valganciclovir HCl is a polar hydrophilic compound with a solubility of 70 mg/mL
in water at 25°C at a pH of 7.0 and an n-octanol/water partition coefficient
of 0.0095 at pH 7.0. The pKa for valganciclovir HCl is 7.6.
The chemical structure of valganciclovir HCl is:








All doses in this insert are specified in terms of valganciclovir.
Last reviewed on RxList: 9/8/2010




Valcyte Drug Description
Valcyte
(valganciclovir hydrochloride) Tablets
Valcyte
(valganciclovir hydrochloride) for Oral Solution

WARNING
HEMATOLOGIC TOXICITY, CARCINOGENICITY, TERATOGENICITY, AND IMPAIRMENT OF
FERTILITY

Clinical toxicity of Valcyte, which is metabolized to ganciclovir, includes
granulocytopenia, anemia, and thrombocytopenia [see WARNINGS AND PRECAUTIONS].
In animal studies, ganciclovir was carcinogenic, teratogenic, and caused
aspermatogenesis [see WARNINGS AND PRECAUTIONS].


DRUG DESCRIPTION



What are the possible side effects of valganciclovir (Valcyte)?

Stop taking valganciclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
easy bruising, unusual bleeding;
numbness or tingling in a part of the body;
signs of infection (fever, chills, body aches, flu symptoms); or
seizure...
Read All Potential Side Effects for Valcyte »




Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride
salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers.
Ganciclovir is a synthetic guanine derivative active against CMV.
Valcyte is available as a 450 mg tablet for oral administration. Each tablet
contains 496.3 mg of valganciclovir HCl (corresponding to 450 mg of valganciclovir),
and the inactive ingredients microcrystalline cellulose, povidone K-30, crospovidone
and stearic acid. The film-coat applied to the tablets contains Opadry Pink®.
Valcyte is also available as a powder for oral solution, which when constituted
with water as directed contains 50 mg/mL valganciclovir free base. The inactive
ingredients of Valcyte for oral solution are sodium benzoate, fumaric acid,
povidone K-30, sodium saccharin, mannitol and tutti-frutti flavoring.
Valganciclovir HCl is a white to off-white crystalline powder with a molecular
formula of C14H22N6O5路HCl and a
molecular weight of 390.83. The chemical name for valganciclovir HCl is L-Valine,
2[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride.
Valganciclovir HCl is a polar hydrophilic compound with a solubility of 70 mg/mL
in water at 25°C at a pH of 7.0 and an n-octanol/water partition coefficient
of 0.0095 at pH 7.0. The pKa for valganciclovir HCl is 7.6.
The chemical structure of valganciclovir HCl is:








All doses in this insert are specified in terms of valganciclovir.
Last reviewed on RxList: 9/8/2010




Valcyte Drug Description
Valcyte
(valganciclovir hydrochloride) Tablets
Valcyte
(valganciclovir hydrochloride) for Oral Solution

WARNING
HEMATOLOGIC TOXICITY, CARCINOGENICITY, TERATOGENICITY, AND IMPAIRMENT OF
FERTILITY

Clinical toxicity of Valcyte, which is metabolized to ganciclovir, includes
granulocytopenia, anemia, and thrombocytopenia [see WARNINGS AND PRECAUTIONS].
In animal studies, ganciclovir was carcinogenic, teratogenic, and caused
aspermatogenesis [see WARNINGS AND PRECAUTIONS].


DRUG DESCRIPTION



What are the possible side effects of valganciclovir (Valcyte)?

Stop taking valganciclovir and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
easy bruising, unusual bleeding;
numbness or tingling in a part of the body;
signs of infection (fever, chills, body aches, flu symptoms); or
seizure...
Read All Potential Side Effects for Valcyte »




Valcyte contains valganciclovir hydrochloride (valganciclovir HCl), a hydrochloride
salt of the L-valyl ester of ganciclovir that exists as a mixture of two diastereomers.
Ganciclovir is a synthetic guanine derivative active against CMV.
Valcyte is available as a 450 mg tablet for oral administration. Each tablet
contains 496.3 mg of valganciclovir HCl (corresponding to 450 mg of valganciclovir),
and the inactive ingredients microcrystalline cellulose, povidone K-30, crospovidone
and stearic acid. The film-coat applied to the tablets contains Opadry Pink®.
Valcyte is also available as a powder for oral solution, which when constituted
with water as directed contains 50 mg/mL valganciclovir free base. The inactive
ingredients of Valcyte for oral solution are sodium benzoate, fumaric acid,
povidone K-30, sodium saccharin, mannitol and tutti-frutti flavoring.
Valganciclovir HCl is a white to off-white crystalline powder with a molecular
formula of C14H22N6O5路HCl and a
molecular weight of 390.83. The chemical name for valganciclovir HCl is L-Valine,
2[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, monohydrochloride.
Valganciclovir HCl is a polar hydrophilic compound with a solubility of 70 mg/mL
in water at 25°C at a pH of 7.0 and an n-octanol/water partition coefficient
of 0.0095 at pH 7.0. The pKa for valganciclovir HCl is 7.6.
The chemical structure of valganciclovir HCl is:








All doses in this insert are specified in terms of valganciclovir.
Last reviewed on RxList: 9/8/2010





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FOLLOW THIS LINK FOR ENTER TO TRUSTED & REPUTABLE ONLINE DRUGSTORE WHERE YOU CAN GET ALL QUALIFIED INFORMATION ABOUT Valcyte ONLINE     Want to increase your potassium large areas. have […]


Transplant Day 19
  by jeffsher63
Good day yesterday. Input and output are better than the previous day, my BP today is lower (but not too low), no fever, and my weight is down […]


Transplant Week 20
  by jeffsher63
Yes, it's been a full 20 weeks since transplant, and everything is going well. I had appointments last week with the Transplant Surgeon and Nurse, and the Transplant Nephrologist. Back […]


Study Proves Longer Prophylactic Therapy With Valcyte Increases Protection Against CMV - Most Serious Viral Infection Affecting Transplant Patients
  by enartion
Roche announced today that a Phase III study investigating the efficacy and safety of extended preventative therapy ('prophylaxis') with Valcyte (oral valganciclovir) met its primary endpoint of […]


Gratitude Friday
  by daphne
I am very tired. Let's just put it this way: when I got to work this morning and tried to sign in, I had to spend several seconds […]


Back In The (Valcyte) Saddle Again
  by daphne
Well, we had quite a day!So, Terri finished up her six months on Valcyte last week. We were thrilled when, at the 5 month mark, she suddenly had […]


Saturday
  by gaylechipman
Man it's hot here today.聽 Where's the ice cream? I'm聽soldiering on here.聽 Lungs are clear, no fever, appetite is improved, drinking water, walking laps in the house and exercises […]


Crackers, No Thank You
  by gaylechipman
A one lab week, not bad. 聽Come Monday only 10 more days of high dose Valcyte round two. I seem not so dizzy and spaced out, so maybe […]


Indian patent office revoked patent of Valcyte
  by managelegally
Indian patent office recently revoked the patent of Valcyte. The patent was granted to Swiss drug maker F. Hoffmann-La Roche Ltd. This was done due to the opposition […]


FDA MedWatch - Valcyte (valganciclovir hydrochloride) Label Change
  by irbtipoftheweek
ISSUE: FDA is notifying healthcare professionals of new pediatric dosing recommendations for Valcyte (valganciclovir hydrochloride) oral tablets and oral solution. FDA has determined that adding an upper limit […]



Other reviews about Valcyte on web:

Learn about the prescription medication Valcyte (Valganciclovir Hcl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Valcyte (Valganciclovir Hcl) Drug Information: Uses, Side Effects ...


Full Prescribing Information (395K/PDF) Important Patient Information (160K/PDF) Valcyte脙聜脗庐 (valganciclovir) is an antiviral medicine. In adults, it is used to treat cytomegalovirus ... Genentech: Medicines: Valcyte


Accurate, FDA approved Valcyte information for healthcare professionals and patients - brought to you by Drugs.com. Valcyte Official FDA information, side effects and uses.


Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is ... Valganciclovir - Wikipedia, the free encyclopedia


All about Valcyte Tablets. View complete and up to date Valcyte information - part of the Drugs.com trusted medication database. Valcyte Tablets Facts and Comparisons at Drugs.com


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Learn about Valcyte from the publishers of the Physicians Desk Reference. Find prescription drug information resources including interactions, side effects, symptoms, treatment ... Valcyte | Prescription Drug Information, Side Effects | PDRHealth


Consumer information about the medication VALGANCICLOVIR- ORAL (Valcyte), includes side effects, drug interactions, recommended dosages, and storage information. Read more ... VALGANCICLOVIR- ORAL (Valcyte) side effects, medical uses, and ...


1 HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use Valcyte 脙聜脗庐 safely and effectively. See full prescribing information ... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not ...





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