Reviews Timoptic in Ocudose


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Timoptic in Ocudose Drug Description
TIMOPTIC®
(timolol maleate) Ophthalmic Solution In Ocudose® (Dispenser) 0.25% AND
0.5%
PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION in a Sterile Ophthalmic
Unit Dose Dispenser

DRUG DESCRIPTION



What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

swelling or redness of your eyelids;
eye redness, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
depressed mood, confusion, hallucinations, unusual thoughts...
Read All Potential Side Effects for Timoptic in Ocudose »




Timolol maleate is a non-selective beta-adrenergic receptor blocking agent.
Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in
its structure and is provided as the levo-isomer. The optical rotation of timolol
maleate is:




[α]
25°
in 1.0N HCl (C
= 5%) = –12.2° (–11.7° to –12.5°).


 


405 nm



Its molecular formula is C13H24N4O3S•C4H4O4
and its structural formula is:








Timolol maleate has a molecular weight of 432.50. It is a white, odorless,
crystalline powder which is soluble in water, methanol, and alcohol.
Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution
is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol
maleate ophthalmic solution), which contains the preservative benzalkonium chloride;
and Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution),
the preservative-free formulation.
Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit
dose container, as a sterile, isotonic, buffered, aqueous solution of timolol
maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE
0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the
solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of
Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg
of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate,
sodium hydroxide to adjust pH, and water for injection.
Last reviewed on RxList: 1/30/2009




Timoptic in Ocudose Drug Description
TIMOPTIC®
(timolol maleate) Ophthalmic Solution In Ocudose® (Dispenser) 0.25% AND
0.5%
PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION in a Sterile Ophthalmic
Unit Dose Dispenser

DRUG DESCRIPTION



What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

swelling or redness of your eyelids;
eye redness, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
depressed mood, confusion, hallucinations, unusual thoughts...
Read All Potential Side Effects for Timoptic in Ocudose »




Timolol maleate is a non-selective beta-adrenergic receptor blocking agent.
Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in
its structure and is provided as the levo-isomer. The optical rotation of timolol
maleate is:




[α]
25°
in 1.0N HCl (C
= 5%) = –12.2° (–11.7° to –12.5°).


 


405 nm



Its molecular formula is C13H24N4O3S•C4H4O4
and its structural formula is:








Timolol maleate has a molecular weight of 432.50. It is a white, odorless,
crystalline powder which is soluble in water, methanol, and alcohol.
Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution
is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol
maleate ophthalmic solution), which contains the preservative benzalkonium chloride;
and Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution),
the preservative-free formulation.
Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit
dose container, as a sterile, isotonic, buffered, aqueous solution of timolol
maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE
0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the
solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of
Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg
of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate,
sodium hydroxide to adjust pH, and water for injection.
Last reviewed on RxList: 1/30/2009




Timoptic in Ocudose Drug Description
TIMOPTIC®
(timolol maleate) Ophthalmic Solution In Ocudose® (Dispenser) 0.25% AND
0.5%
PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION in a Sterile Ophthalmic
Unit Dose Dispenser

DRUG DESCRIPTION



What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

swelling or redness of your eyelids;
eye redness, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
depressed mood, confusion, hallucinations, unusual thoughts...
Read All Potential Side Effects for Timoptic in Ocudose »




Timolol maleate is a non-selective beta-adrenergic receptor blocking agent.
Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in
its structure and is provided as the levo-isomer. The optical rotation of timolol
maleate is:




[α]
25°
in 1.0N HCl (C
= 5%) = –12.2° (–11.7° to –12.5°).


 


405 nm



Its molecular formula is C13H24N4O3S•C4H4O4
and its structural formula is:








Timolol maleate has a molecular weight of 432.50. It is a white, odorless,
crystalline powder which is soluble in water, methanol, and alcohol.
Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution
is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol
maleate ophthalmic solution), which contains the preservative benzalkonium chloride;
and Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution),
the preservative-free formulation.
Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit
dose container, as a sterile, isotonic, buffered, aqueous solution of timolol
maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE
0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the
solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of
Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg
of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate,
sodium hydroxide to adjust pH, and water for injection.
Last reviewed on RxList: 1/30/2009




Timoptic in Ocudose Drug Description
TIMOPTIC®
(timolol maleate) Ophthalmic Solution In Ocudose® (Dispenser) 0.25% AND
0.5%
PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION in a Sterile Ophthalmic
Unit Dose Dispenser

DRUG DESCRIPTION



What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

swelling or redness of your eyelids;
eye redness, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
depressed mood, confusion, hallucinations, unusual thoughts...
Read All Potential Side Effects for Timoptic in Ocudose »




Timolol maleate is a non-selective beta-adrenergic receptor blocking agent.
Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in
its structure and is provided as the levo-isomer. The optical rotation of timolol
maleate is:




[α]
25°
in 1.0N HCl (C
= 5%) = –12.2° (–11.7° to –12.5°).


 


405 nm



Its molecular formula is C13H24N4O3S•C4H4O4
and its structural formula is:








Timolol maleate has a molecular weight of 432.50. It is a white, odorless,
crystalline powder which is soluble in water, methanol, and alcohol.
Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution
is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol
maleate ophthalmic solution), which contains the preservative benzalkonium chloride;
and Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution),
the preservative-free formulation.
Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit
dose container, as a sterile, isotonic, buffered, aqueous solution of timolol
maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE
0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the
solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of
Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg
of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate,
sodium hydroxide to adjust pH, and water for injection.
Last reviewed on RxList: 1/30/2009




Timoptic in Ocudose Drug Description
TIMOPTIC®
(timolol maleate) Ophthalmic Solution In Ocudose® (Dispenser) 0.25% AND
0.5%
PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION in a Sterile Ophthalmic
Unit Dose Dispenser

DRUG DESCRIPTION



What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:

swelling or redness of your eyelids;
eye redness, discomfort, or sensitivity to light;
drainage, crusting, or oozing of your eyes or eyelids;
depressed mood, confusion, hallucinations, unusual thoughts...
Read All Potential Side Effects for Timoptic in Ocudose »




Timolol maleate is a non-selective beta-adrenergic receptor blocking agent.
Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol
maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in
its structure and is provided as the levo-isomer. The optical rotation of timolol
maleate is:




[α]
25°
in 1.0N HCl (C
= 5%) = –12.2° (–11.7° to –12.5°).


 


405 nm



Its molecular formula is C13H24N4O3S•C4H4O4
and its structural formula is:








Timolol maleate has a molecular weight of 432.50. It is a white, odorless,
crystalline powder which is soluble in water, methanol, and alcohol.
Timolol maleate is stable at room temperature. Timolol maleate ophthalmic solution
is supplied in two formulations: Ophthalmic Solution TIMOPTIC* (timolol
maleate ophthalmic solution), which contains the preservative benzalkonium chloride;
and Ophthalmic Solution TIMOPTIC* (timolol maleate ophthalmic solution),
the preservative-free formulation.
Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit
dose container, as a sterile, isotonic, buffered, aqueous solution of timolol
maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE
0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the
solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of
Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg
of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate,
sodium hydroxide to adjust pH, and water for injection.
Last reviewed on RxList: 1/30/2009





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For Timoptic in Ocudose single-use containers, the medication must be used or discarded within one month once the outer foil packaging is opened. Timoptic


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