Reviews Thrombin Topical Bovine Origin


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Thrombin-JMI Drug Description
THROMBIN, TOPICAL U.S.P.
(bovine origin)
THROMBIN-JMI®
Thrombin, Topical (Bovine) must not be injected! Apply on the surface of
bleeding tissue.
DRUG DESCRIPTION
The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMI® is a protein substance produced through a conversion reaction in which prothrombin of bovine
origin is activated by tissue thromboplastin of bovine origin in the presence
of calcium chloride. It is supplied as a sterile powder that has been freeze-dried
in the final container. Also contained in the preparation are mannitol and sodium
chloride. Mannitol is included to make the dried product friable and more readily
soluble. The material contains no preservative.
THROMBIN-JMI® has been chromatographically purified and further processed
by ultrafiltration. Analytical studies demonstrate the current manufacturing
process' capability to remove significant amounts of extraneous proteins, and
result in a reduction of Factor Va light chain content to levels below the limit
of detection of semi-quantitative Western Blot assay ( < 92 ng/mL, when reconstituted
as directed). The clinical significance of these findings is unknown.Last reviewed on RxList: 10/14/2008




Thrombin-JMI Drug Description
THROMBIN, TOPICAL U.S.P.
(bovine origin)
THROMBIN-JMI®
Thrombin, Topical (Bovine) must not be injected! Apply on the surface of
bleeding tissue.
DRUG DESCRIPTION
The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMI® is a protein substance produced through a conversion reaction in which prothrombin of bovine
origin is activated by tissue thromboplastin of bovine origin in the presence
of calcium chloride. It is supplied as a sterile powder that has been freeze-dried
in the final container. Also contained in the preparation are mannitol and sodium
chloride. Mannitol is included to make the dried product friable and more readily
soluble. The material contains no preservative.
THROMBIN-JMI® has been chromatographically purified and further processed
by ultrafiltration. Analytical studies demonstrate the current manufacturing
process' capability to remove significant amounts of extraneous proteins, and
result in a reduction of Factor Va light chain content to levels below the limit
of detection of semi-quantitative Western Blot assay ( < 92 ng/mL, when reconstituted
as directed). The clinical significance of these findings is unknown.Last reviewed on RxList: 10/14/2008




Thrombin-JMI Drug Description
THROMBIN, TOPICAL U.S.P.
(bovine origin)
THROMBIN-JMI®
Thrombin, Topical (Bovine) must not be injected! Apply on the surface of
bleeding tissue.
DRUG DESCRIPTION
The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMI® is a protein substance produced through a conversion reaction in which prothrombin of bovine
origin is activated by tissue thromboplastin of bovine origin in the presence
of calcium chloride. It is supplied as a sterile powder that has been freeze-dried
in the final container. Also contained in the preparation are mannitol and sodium
chloride. Mannitol is included to make the dried product friable and more readily
soluble. The material contains no preservative.
THROMBIN-JMI® has been chromatographically purified and further processed
by ultrafiltration. Analytical studies demonstrate the current manufacturing
process' capability to remove significant amounts of extraneous proteins, and
result in a reduction of Factor Va light chain content to levels below the limit
of detection of semi-quantitative Western Blot assay ( < 92 ng/mL, when reconstituted
as directed). The clinical significance of these findings is unknown.Last reviewed on RxList: 10/14/2008




Thrombin-JMI Drug Description
THROMBIN, TOPICAL U.S.P.
(bovine origin)
THROMBIN-JMI®
Thrombin, Topical (Bovine) must not be injected! Apply on the surface of
bleeding tissue.
DRUG DESCRIPTION
The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMI® is a protein substance produced through a conversion reaction in which prothrombin of bovine
origin is activated by tissue thromboplastin of bovine origin in the presence
of calcium chloride. It is supplied as a sterile powder that has been freeze-dried
in the final container. Also contained in the preparation are mannitol and sodium
chloride. Mannitol is included to make the dried product friable and more readily
soluble. The material contains no preservative.
THROMBIN-JMI® has been chromatographically purified and further processed
by ultrafiltration. Analytical studies demonstrate the current manufacturing
process' capability to remove significant amounts of extraneous proteins, and
result in a reduction of Factor Va light chain content to levels below the limit
of detection of semi-quantitative Western Blot assay ( < 92 ng/mL, when reconstituted
as directed). The clinical significance of these findings is unknown.Last reviewed on RxList: 10/14/2008




Thrombin-JMI Drug Description
THROMBIN, TOPICAL U.S.P.
(bovine origin)
THROMBIN-JMI®
Thrombin, Topical (Bovine) must not be injected! Apply on the surface of
bleeding tissue.
DRUG DESCRIPTION
The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMI® is a protein substance produced through a conversion reaction in which prothrombin of bovine
origin is activated by tissue thromboplastin of bovine origin in the presence
of calcium chloride. It is supplied as a sterile powder that has been freeze-dried
in the final container. Also contained in the preparation are mannitol and sodium
chloride. Mannitol is included to make the dried product friable and more readily
soluble. The material contains no preservative.
THROMBIN-JMI® has been chromatographically purified and further processed
by ultrafiltration. Analytical studies demonstrate the current manufacturing
process' capability to remove significant amounts of extraneous proteins, and
result in a reduction of Factor Va light chain content to levels below the limit
of detection of semi-quantitative Western Blot assay ( < 92 ng/mL, when reconstituted
as directed). The clinical significance of these findings is unknown.Last reviewed on RxList: 10/14/2008





Other reviews about Thrombin Topical Bovine Origin on web:

Learn about the prescription medication Thrombin-JMI (Thrombin Topical Bovine Origin), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Thrombin-JMI (Thrombin Topical Bovine Origin) Drug Information ...


Thrombin-JMI テδづつョ (Thrombin, Topical, Bovine Origin, U.S.P.) is indicated as an aid to hemostasis whenever oozing blood and minor bleeding from capillaries and small venules is ... Thrombin-JMIテδづつョ- Home


THROMBIN, TOPICAL U.S.P. (BOVINE ORIGIN) THROMBIN-JMI テδづつョ Thrombin, Topical (Bovine) must not be injected! Apply on the surface of bleeding tissue. THROMBIN, TOPICAL U.S.P.


Thrombin-JMI テδづつョ (Thrombin, Topical, Bovine Origin, U.S.P.) is indicated as an aid to hemostasis whenever oozing blood and minor bleeding from capillaries and small venules is ... Thrombin-JMI | FAQs


The initial thrombin was bovine in origin, but its use has been complicated by the formation ... JG, Johnson RK, Lesher AP, et al. Exposure of mice to topical bovine thrombin induces ... Clinical use of topical thrombin as a surgical hemostat


THROMBOSTATテδ「テつテつ「 Parke-Davis Thrombin (Bovine Origin) Topical Hemostatic Action and Clinical Thrombostat is a protein substance produced through a conversion reaction in which ... RxMed: Pharmaceutical Information - THROMBOSTAT


DESCRIPTION The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMIテδづつョ is a protein substance produced through a conversion reaction in which prothrombin of bovine ... Thrombin Topical


THROMBIN-JMI SUMMARY The thrombin in Thrombin, Topical (Bovine Origin) THROMBIN-JMIテδづつョ is a protein substance produced through a conversion reaction in which prothrombin of ... Thrombin-JMI (Thrombin Topical) - Drug Info, Side Effects ...


A Phase 4, Multicenter, Open-Label, Observational Study Assessing the Impact of Exposure to THROMBIN-JMIテδづつョ (Thrombin, Topical U.S.P [Bovine Origin]) on Coagulation Parameters Observational Study Assessing the Impact of Exposure to THROMBIN ...


Thrombin, Topical U.S.P. (Bovine Origin): THROMBIN-JMI テδづつョ Instructions for Use テδ「テつテつ Rev. 6/98. Table 1. Patient Demographics and Distribution ... Antigenic Responses to Bovine Thrombin Exposure During Surgery: A ...





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