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Temodar Drug Description
TEMODAR
(temozolomide) Capsules
TEMODAR
(temozolomide) for Injection
Administered via Intravenous Infusion
DRUG DESCRIPTION



What are the possible side effects of temozolomide (Temodar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
numbness or tingling on one side of your body;
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual...
Read All Potential Side Effects for Temodar »




TEMODAR contains temozolomide, an imidazotetrazine derivative. The chemical
name of temozolomide is 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide.
The structural formula is:








The material is a white to light tan/light pink powder with a molecular formula
of C6H6N6O2 and a molecular weight
of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7;
hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide,
is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide
(MTIC) at neutral and alkaline pH values, with hydrolysis taking place even
faster at alkaline pH.
TEMODAR Capsules
Each capsule for oral use contains either 5 mg, 20 mg, 100 mg, 140 mg, 180
mg, or 250 mg of temozolomide.
The inactive ingredients for TEMODAR Capsules are as follows:
TEMODAR 5 mg: lactose anhydrous (132.8 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (7.5 mg), tartaric acid (1.5 mg), and stearic acid
(3 mg).
TEMODAR 20 mg: lactose anhydrous (182.2 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (11 mg), tartaric acid (2.2 mg), and stearic acid
(4.4 mg).
TEMODAR 100 mg: lactose anhydrous (175.7 mg), colloidal silicon dioxide (0.3
mg), sodium starch glycolate (15 mg), tartaric acid (3 mg), and stearic acid
(6 mg).
TEMODAR 140 mg: lactose anhydrous (246 mg), colloidal silicon dioxide (0.4
mg), sodium starch glycolate (21 mg), tartaric acid (4.2 mg), and stearic acid
(8.4 mg).
TEMODAR 180 mg: lactose anhydrous (316.3 mg), colloidal silicon dioxide (0.5
mg), sodium starch glycolate (27 mg), tartaric acid (5.4 mg), and stearic acid
(10.8 mg).
TEMODAR 250 mg: lactose anhydrous (154.3 mg), colloidal silicon dioxide (0.7
mg), sodium starch glycolate (22.5 mg), tartaric acid (9 mg), and stearic acid
(13.5 mg).
The body of the capsules are made of gelatin, and are opaque white. The cap
is also made of gelatin, and the colors vary based on the dosage strength. The
capsule body and cap are imprinted with pharmaceutical branding ink, which contains
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol,
purified water, strong ammonia solution, potassium hydroxide, and ferric oxide.
TEMODAR 5 mg: The green cap contains gelatin, titanium dioxide, iron oxide
yellow, sodium lauryl sulfate, and FD&C Blue #2.
TEMODAR 20 mg: The yellow cap contains gelatin, sodium lauryl sulfate, and
iron oxide yellow.
TEMODAR 100 mg:The pink cap contains gelatin, titanium dioxide, sodium lauryl
sulfate, and iron oxide red.
TEMODAR 140 mg: The blue cap contains gelatin, sodium lauryl sulfate, and FD&C
Blue #2.
TEMODAR 180 mg: The orange cap contains gelatin, iron oxide red, iron oxide
yellow, titanium dioxide, and sodium lauryl sulfate.
TEMODAR 250 mg: The white cap contains gelatin, titanium dioxide, and sodium
lauryl sulfate.

TEMODAR for Injection
Each vial contains 100 mg of sterile and pyrogen-free temozolomide lyophilized
powder for intravenous injection. The inactive ingredients are: mannitol (600
mg), L-threonine (160 mg), polysorbate 80 (120 mg), sodium citrate dihydrate
(235 mg), and hydrochloric acid (160 mg).
Last reviewed on RxList: 5/20/2010




Temodar Drug Description
TEMODAR
(temozolomide) Capsules
TEMODAR
(temozolomide) for Injection
Administered via Intravenous Infusion
DRUG DESCRIPTION



What are the possible side effects of temozolomide (Temodar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
numbness or tingling on one side of your body;
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual...
Read All Potential Side Effects for Temodar »




TEMODAR contains temozolomide, an imidazotetrazine derivative. The chemical
name of temozolomide is 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide.
The structural formula is:








The material is a white to light tan/light pink powder with a molecular formula
of C6H6N6O2 and a molecular weight
of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7;
hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide,
is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide
(MTIC) at neutral and alkaline pH values, with hydrolysis taking place even
faster at alkaline pH.
TEMODAR Capsules
Each capsule for oral use contains either 5 mg, 20 mg, 100 mg, 140 mg, 180
mg, or 250 mg of temozolomide.
The inactive ingredients for TEMODAR Capsules are as follows:
TEMODAR 5 mg: lactose anhydrous (132.8 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (7.5 mg), tartaric acid (1.5 mg), and stearic acid
(3 mg).
TEMODAR 20 mg: lactose anhydrous (182.2 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (11 mg), tartaric acid (2.2 mg), and stearic acid
(4.4 mg).
TEMODAR 100 mg: lactose anhydrous (175.7 mg), colloidal silicon dioxide (0.3
mg), sodium starch glycolate (15 mg), tartaric acid (3 mg), and stearic acid
(6 mg).
TEMODAR 140 mg: lactose anhydrous (246 mg), colloidal silicon dioxide (0.4
mg), sodium starch glycolate (21 mg), tartaric acid (4.2 mg), and stearic acid
(8.4 mg).
TEMODAR 180 mg: lactose anhydrous (316.3 mg), colloidal silicon dioxide (0.5
mg), sodium starch glycolate (27 mg), tartaric acid (5.4 mg), and stearic acid
(10.8 mg).
TEMODAR 250 mg: lactose anhydrous (154.3 mg), colloidal silicon dioxide (0.7
mg), sodium starch glycolate (22.5 mg), tartaric acid (9 mg), and stearic acid
(13.5 mg).
The body of the capsules are made of gelatin, and are opaque white. The cap
is also made of gelatin, and the colors vary based on the dosage strength. The
capsule body and cap are imprinted with pharmaceutical branding ink, which contains
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol,
purified water, strong ammonia solution, potassium hydroxide, and ferric oxide.
TEMODAR 5 mg: The green cap contains gelatin, titanium dioxide, iron oxide
yellow, sodium lauryl sulfate, and FD&C Blue #2.
TEMODAR 20 mg: The yellow cap contains gelatin, sodium lauryl sulfate, and
iron oxide yellow.
TEMODAR 100 mg:The pink cap contains gelatin, titanium dioxide, sodium lauryl
sulfate, and iron oxide red.
TEMODAR 140 mg: The blue cap contains gelatin, sodium lauryl sulfate, and FD&C
Blue #2.
TEMODAR 180 mg: The orange cap contains gelatin, iron oxide red, iron oxide
yellow, titanium dioxide, and sodium lauryl sulfate.
TEMODAR 250 mg: The white cap contains gelatin, titanium dioxide, and sodium
lauryl sulfate.

TEMODAR for Injection
Each vial contains 100 mg of sterile and pyrogen-free temozolomide lyophilized
powder for intravenous injection. The inactive ingredients are: mannitol (600
mg), L-threonine (160 mg), polysorbate 80 (120 mg), sodium citrate dihydrate
(235 mg), and hydrochloric acid (160 mg).
Last reviewed on RxList: 5/20/2010




Temodar Drug Description
TEMODAR
(temozolomide) Capsules
TEMODAR
(temozolomide) for Injection
Administered via Intravenous Infusion
DRUG DESCRIPTION



What are the possible side effects of temozolomide (Temodar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
numbness or tingling on one side of your body;
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual...
Read All Potential Side Effects for Temodar »




TEMODAR contains temozolomide, an imidazotetrazine derivative. The chemical
name of temozolomide is 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide.
The structural formula is:








The material is a white to light tan/light pink powder with a molecular formula
of C6H6N6O2 and a molecular weight
of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7;
hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide,
is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide
(MTIC) at neutral and alkaline pH values, with hydrolysis taking place even
faster at alkaline pH.
TEMODAR Capsules
Each capsule for oral use contains either 5 mg, 20 mg, 100 mg, 140 mg, 180
mg, or 250 mg of temozolomide.
The inactive ingredients for TEMODAR Capsules are as follows:
TEMODAR 5 mg: lactose anhydrous (132.8 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (7.5 mg), tartaric acid (1.5 mg), and stearic acid
(3 mg).
TEMODAR 20 mg: lactose anhydrous (182.2 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (11 mg), tartaric acid (2.2 mg), and stearic acid
(4.4 mg).
TEMODAR 100 mg: lactose anhydrous (175.7 mg), colloidal silicon dioxide (0.3
mg), sodium starch glycolate (15 mg), tartaric acid (3 mg), and stearic acid
(6 mg).
TEMODAR 140 mg: lactose anhydrous (246 mg), colloidal silicon dioxide (0.4
mg), sodium starch glycolate (21 mg), tartaric acid (4.2 mg), and stearic acid
(8.4 mg).
TEMODAR 180 mg: lactose anhydrous (316.3 mg), colloidal silicon dioxide (0.5
mg), sodium starch glycolate (27 mg), tartaric acid (5.4 mg), and stearic acid
(10.8 mg).
TEMODAR 250 mg: lactose anhydrous (154.3 mg), colloidal silicon dioxide (0.7
mg), sodium starch glycolate (22.5 mg), tartaric acid (9 mg), and stearic acid
(13.5 mg).
The body of the capsules are made of gelatin, and are opaque white. The cap
is also made of gelatin, and the colors vary based on the dosage strength. The
capsule body and cap are imprinted with pharmaceutical branding ink, which contains
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol,
purified water, strong ammonia solution, potassium hydroxide, and ferric oxide.
TEMODAR 5 mg: The green cap contains gelatin, titanium dioxide, iron oxide
yellow, sodium lauryl sulfate, and FD&C Blue #2.
TEMODAR 20 mg: The yellow cap contains gelatin, sodium lauryl sulfate, and
iron oxide yellow.
TEMODAR 100 mg:The pink cap contains gelatin, titanium dioxide, sodium lauryl
sulfate, and iron oxide red.
TEMODAR 140 mg: The blue cap contains gelatin, sodium lauryl sulfate, and FD&C
Blue #2.
TEMODAR 180 mg: The orange cap contains gelatin, iron oxide red, iron oxide
yellow, titanium dioxide, and sodium lauryl sulfate.
TEMODAR 250 mg: The white cap contains gelatin, titanium dioxide, and sodium
lauryl sulfate.

TEMODAR for Injection
Each vial contains 100 mg of sterile and pyrogen-free temozolomide lyophilized
powder for intravenous injection. The inactive ingredients are: mannitol (600
mg), L-threonine (160 mg), polysorbate 80 (120 mg), sodium citrate dihydrate
(235 mg), and hydrochloric acid (160 mg).
Last reviewed on RxList: 5/20/2010




Temodar Drug Description
TEMODAR
(temozolomide) Capsules
TEMODAR
(temozolomide) for Injection
Administered via Intravenous Infusion
DRUG DESCRIPTION



What are the possible side effects of temozolomide (Temodar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
numbness or tingling on one side of your body;
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual...
Read All Potential Side Effects for Temodar »




TEMODAR contains temozolomide, an imidazotetrazine derivative. The chemical
name of temozolomide is 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide.
The structural formula is:








The material is a white to light tan/light pink powder with a molecular formula
of C6H6N6O2 and a molecular weight
of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7;
hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide,
is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide
(MTIC) at neutral and alkaline pH values, with hydrolysis taking place even
faster at alkaline pH.
TEMODAR Capsules
Each capsule for oral use contains either 5 mg, 20 mg, 100 mg, 140 mg, 180
mg, or 250 mg of temozolomide.
The inactive ingredients for TEMODAR Capsules are as follows:
TEMODAR 5 mg: lactose anhydrous (132.8 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (7.5 mg), tartaric acid (1.5 mg), and stearic acid
(3 mg).
TEMODAR 20 mg: lactose anhydrous (182.2 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (11 mg), tartaric acid (2.2 mg), and stearic acid
(4.4 mg).
TEMODAR 100 mg: lactose anhydrous (175.7 mg), colloidal silicon dioxide (0.3
mg), sodium starch glycolate (15 mg), tartaric acid (3 mg), and stearic acid
(6 mg).
TEMODAR 140 mg: lactose anhydrous (246 mg), colloidal silicon dioxide (0.4
mg), sodium starch glycolate (21 mg), tartaric acid (4.2 mg), and stearic acid
(8.4 mg).
TEMODAR 180 mg: lactose anhydrous (316.3 mg), colloidal silicon dioxide (0.5
mg), sodium starch glycolate (27 mg), tartaric acid (5.4 mg), and stearic acid
(10.8 mg).
TEMODAR 250 mg: lactose anhydrous (154.3 mg), colloidal silicon dioxide (0.7
mg), sodium starch glycolate (22.5 mg), tartaric acid (9 mg), and stearic acid
(13.5 mg).
The body of the capsules are made of gelatin, and are opaque white. The cap
is also made of gelatin, and the colors vary based on the dosage strength. The
capsule body and cap are imprinted with pharmaceutical branding ink, which contains
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol,
purified water, strong ammonia solution, potassium hydroxide, and ferric oxide.
TEMODAR 5 mg: The green cap contains gelatin, titanium dioxide, iron oxide
yellow, sodium lauryl sulfate, and FD&C Blue #2.
TEMODAR 20 mg: The yellow cap contains gelatin, sodium lauryl sulfate, and
iron oxide yellow.
TEMODAR 100 mg:The pink cap contains gelatin, titanium dioxide, sodium lauryl
sulfate, and iron oxide red.
TEMODAR 140 mg: The blue cap contains gelatin, sodium lauryl sulfate, and FD&C
Blue #2.
TEMODAR 180 mg: The orange cap contains gelatin, iron oxide red, iron oxide
yellow, titanium dioxide, and sodium lauryl sulfate.
TEMODAR 250 mg: The white cap contains gelatin, titanium dioxide, and sodium
lauryl sulfate.

TEMODAR for Injection
Each vial contains 100 mg of sterile and pyrogen-free temozolomide lyophilized
powder for intravenous injection. The inactive ingredients are: mannitol (600
mg), L-threonine (160 mg), polysorbate 80 (120 mg), sodium citrate dihydrate
(235 mg), and hydrochloric acid (160 mg).
Last reviewed on RxList: 5/20/2010




Temodar Drug Description
TEMODAR
(temozolomide) Capsules
TEMODAR
(temozolomide) for Injection
Administered via Intravenous Infusion
DRUG DESCRIPTION



What are the possible side effects of temozolomide (Temodar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);
numbness or tingling on one side of your body;
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual...
Read All Potential Side Effects for Temodar »




TEMODAR contains temozolomide, an imidazotetrazine derivative. The chemical
name of temozolomide is 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide.
The structural formula is:








The material is a white to light tan/light pink powder with a molecular formula
of C6H6N6O2 and a molecular weight
of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7;
hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide,
is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide
(MTIC) at neutral and alkaline pH values, with hydrolysis taking place even
faster at alkaline pH.
TEMODAR Capsules
Each capsule for oral use contains either 5 mg, 20 mg, 100 mg, 140 mg, 180
mg, or 250 mg of temozolomide.
The inactive ingredients for TEMODAR Capsules are as follows:
TEMODAR 5 mg: lactose anhydrous (132.8 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (7.5 mg), tartaric acid (1.5 mg), and stearic acid
(3 mg).
TEMODAR 20 mg: lactose anhydrous (182.2 mg), colloidal silicon dioxide (0.2
mg), sodium starch glycolate (11 mg), tartaric acid (2.2 mg), and stearic acid
(4.4 mg).
TEMODAR 100 mg: lactose anhydrous (175.7 mg), colloidal silicon dioxide (0.3
mg), sodium starch glycolate (15 mg), tartaric acid (3 mg), and stearic acid
(6 mg).
TEMODAR 140 mg: lactose anhydrous (246 mg), colloidal silicon dioxide (0.4
mg), sodium starch glycolate (21 mg), tartaric acid (4.2 mg), and stearic acid
(8.4 mg).
TEMODAR 180 mg: lactose anhydrous (316.3 mg), colloidal silicon dioxide (0.5
mg), sodium starch glycolate (27 mg), tartaric acid (5.4 mg), and stearic acid
(10.8 mg).
TEMODAR 250 mg: lactose anhydrous (154.3 mg), colloidal silicon dioxide (0.7
mg), sodium starch glycolate (22.5 mg), tartaric acid (9 mg), and stearic acid
(13.5 mg).
The body of the capsules are made of gelatin, and are opaque white. The cap
is also made of gelatin, and the colors vary based on the dosage strength. The
capsule body and cap are imprinted with pharmaceutical branding ink, which contains
shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol,
purified water, strong ammonia solution, potassium hydroxide, and ferric oxide.
TEMODAR 5 mg: The green cap contains gelatin, titanium dioxide, iron oxide
yellow, sodium lauryl sulfate, and FD&C Blue #2.
TEMODAR 20 mg: The yellow cap contains gelatin, sodium lauryl sulfate, and
iron oxide yellow.
TEMODAR 100 mg:The pink cap contains gelatin, titanium dioxide, sodium lauryl
sulfate, and iron oxide red.
TEMODAR 140 mg: The blue cap contains gelatin, sodium lauryl sulfate, and FD&C
Blue #2.
TEMODAR 180 mg: The orange cap contains gelatin, iron oxide red, iron oxide
yellow, titanium dioxide, and sodium lauryl sulfate.
TEMODAR 250 mg: The white cap contains gelatin, titanium dioxide, and sodium
lauryl sulfate.

TEMODAR for Injection
Each vial contains 100 mg of sterile and pyrogen-free temozolomide lyophilized
powder for intravenous injection. The inactive ingredients are: mannitol (600
mg), L-threonine (160 mg), polysorbate 80 (120 mg), sodium citrate dihydrate
(235 mg), and hydrochloric acid (160 mg).
Last reviewed on RxList: 5/20/2010





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Temozolomide (brand names Temodar and Temodal Schering-Plough Corporation) is an oral alkylating agent which can be used for the treatment of Grade IV astrocytoma-- an aggressive brain ... Temozolomide - Wikipedia, the free encyclopedia


Temozolomide Key Terms: Anaplasia , Anaplastic astrocytoma , DNA . Definition A chemotherapy medicine used to reduce the size of a cancerous tumor and Temozolomide: Information from Answers.com


This page contains brief information about temozolomide and a collection of links to more information about the use of this drug, related research results, and ongoing clinical ... Temozolomide - National Cancer Institute


All about Temozolomide. View complete and up to date Temozolomide information - part of the Drugs.com trusted medication database. Temozolomide Facts and Comparisons at Drugs.com


Adding the drug temozolomide (Temodar®) to radiation therapy for the treatment of a brain tumor called glioblastoma multiforme increased survival in a large randomized trial ... Temozolomide Plus Radiation Helps Brain Cancer - National Cancer ...


TEMODAR brain tumor treatment for the symptoms of brain tumors Temodar® treatment for brain tumors


Consumer information about the medication TEMOZOLOMIDE - ORAL (Temodar), includes side effects, drug interactions, recommended dosages, and storage information. Read more about ... TEMOZOLOMIDE - ORAL (Temodar) side effects, medical uses, and drug ...


Temozolomide is usually given to cancer patients who are under or had undergone radiation therapy commonly for brain tumors.Temozolomide is a drug given to hinder the growth of ... Temozolomide - Kosmix : Reference, Videos, Images, News, Shopping ...


Temozolomide is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. This medication is classified as an alkylating agent. Temodar Temozolomide, Temodar - Chemotherapy Drugs, Chemo Drug Side Effects


Physician reviewed temozolomide (oral) patient information - includes temozolomide description, dosage and directions. temozolomide (oral) medical facts from Drugs.com





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