Reviews Sutent


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Sutent Drug Description
SUTENT®
(sunitinib malate) Capsules, Oral
DRUG DESCRIPTION



What are the possible side effects of sunitinib (Sutent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sunitinib and call your doctor at once if you have any of these serious side effects:

chest pain, general ill feeling;
uneven heart rate;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
weakness, tired feeling, nausea, loss of appetite, weight...
Read All Potential Side Effects for Sutent »




SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib
malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound
with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
(1:1). The molecular formula is C22H27FN4O2
•C4H6O5 and the molecular weight is 532.6
Daltons.
The chemical structure of sunitinib malate is:








Sunitinib malate is a yellow to orange powder with a pKa of 8.95. The solubility of sunitinib malate in aqueous media over the range pH 1.2 to pH 6.8 is in excess of 25 mg/mL. The log of the distribution coefficient (octanol/water) at pH 7 is 5.2.
SUTENT (sunitinib malate) capsules are supplied as printed hard shell capsules containing sunitinib malate equivalent to 12.5 mg, 25 mg or 50 mg of sunitinib together with mannitol, croscarmellose sodium, povidone (K-25) and magnesium stearate as inactive ingredients.
The orange gelatin capsule shells contain titanium dioxide, and red iron oxide. The caramel gelatin capsule shells also contain yellow iron oxide and black iron oxide. The printing ink contains shellac, propylene glycol, sodium hydroxide, povidone and titanium dioxide.
Last reviewed on RxList: 8/24/2009




Sutent Drug Description
SUTENT®
(sunitinib malate) Capsules, Oral
DRUG DESCRIPTION



What are the possible side effects of sunitinib (Sutent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sunitinib and call your doctor at once if you have any of these serious side effects:

chest pain, general ill feeling;
uneven heart rate;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
weakness, tired feeling, nausea, loss of appetite, weight...
Read All Potential Side Effects for Sutent »




SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib
malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound
with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
(1:1). The molecular formula is C22H27FN4O2
•C4H6O5 and the molecular weight is 532.6
Daltons.
The chemical structure of sunitinib malate is:








Sunitinib malate is a yellow to orange powder with a pKa of 8.95. The solubility of sunitinib malate in aqueous media over the range pH 1.2 to pH 6.8 is in excess of 25 mg/mL. The log of the distribution coefficient (octanol/water) at pH 7 is 5.2.
SUTENT (sunitinib malate) capsules are supplied as printed hard shell capsules containing sunitinib malate equivalent to 12.5 mg, 25 mg or 50 mg of sunitinib together with mannitol, croscarmellose sodium, povidone (K-25) and magnesium stearate as inactive ingredients.
The orange gelatin capsule shells contain titanium dioxide, and red iron oxide. The caramel gelatin capsule shells also contain yellow iron oxide and black iron oxide. The printing ink contains shellac, propylene glycol, sodium hydroxide, povidone and titanium dioxide.
Last reviewed on RxList: 8/24/2009




Sutent Drug Description
SUTENT®
(sunitinib malate) Capsules, Oral
DRUG DESCRIPTION



What are the possible side effects of sunitinib (Sutent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sunitinib and call your doctor at once if you have any of these serious side effects:

chest pain, general ill feeling;
uneven heart rate;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
weakness, tired feeling, nausea, loss of appetite, weight...
Read All Potential Side Effects for Sutent »




SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib
malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound
with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
(1:1). The molecular formula is C22H27FN4O2
•C4H6O5 and the molecular weight is 532.6
Daltons.
The chemical structure of sunitinib malate is:








Sunitinib malate is a yellow to orange powder with a pKa of 8.95. The solubility of sunitinib malate in aqueous media over the range pH 1.2 to pH 6.8 is in excess of 25 mg/mL. The log of the distribution coefficient (octanol/water) at pH 7 is 5.2.
SUTENT (sunitinib malate) capsules are supplied as printed hard shell capsules containing sunitinib malate equivalent to 12.5 mg, 25 mg or 50 mg of sunitinib together with mannitol, croscarmellose sodium, povidone (K-25) and magnesium stearate as inactive ingredients.
The orange gelatin capsule shells contain titanium dioxide, and red iron oxide. The caramel gelatin capsule shells also contain yellow iron oxide and black iron oxide. The printing ink contains shellac, propylene glycol, sodium hydroxide, povidone and titanium dioxide.
Last reviewed on RxList: 8/24/2009




Sutent Drug Description
SUTENT®
(sunitinib malate) Capsules, Oral
DRUG DESCRIPTION



What are the possible side effects of sunitinib (Sutent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sunitinib and call your doctor at once if you have any of these serious side effects:

chest pain, general ill feeling;
uneven heart rate;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
weakness, tired feeling, nausea, loss of appetite, weight...
Read All Potential Side Effects for Sutent »




SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib
malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound
with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
(1:1). The molecular formula is C22H27FN4O2
•C4H6O5 and the molecular weight is 532.6
Daltons.
The chemical structure of sunitinib malate is:








Sunitinib malate is a yellow to orange powder with a pKa of 8.95. The solubility of sunitinib malate in aqueous media over the range pH 1.2 to pH 6.8 is in excess of 25 mg/mL. The log of the distribution coefficient (octanol/water) at pH 7 is 5.2.
SUTENT (sunitinib malate) capsules are supplied as printed hard shell capsules containing sunitinib malate equivalent to 12.5 mg, 25 mg or 50 mg of sunitinib together with mannitol, croscarmellose sodium, povidone (K-25) and magnesium stearate as inactive ingredients.
The orange gelatin capsule shells contain titanium dioxide, and red iron oxide. The caramel gelatin capsule shells also contain yellow iron oxide and black iron oxide. The printing ink contains shellac, propylene glycol, sodium hydroxide, povidone and titanium dioxide.
Last reviewed on RxList: 8/24/2009




Sutent Drug Description
SUTENT®
(sunitinib malate) Capsules, Oral
DRUG DESCRIPTION



What are the possible side effects of sunitinib (Sutent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sunitinib and call your doctor at once if you have any of these serious side effects:

chest pain, general ill feeling;
uneven heart rate;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
weakness, tired feeling, nausea, loss of appetite, weight...
Read All Potential Side Effects for Sutent »




SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib
malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound
with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
(1:1). The molecular formula is C22H27FN4O2
•C4H6O5 and the molecular weight is 532.6
Daltons.
The chemical structure of sunitinib malate is:








Sunitinib malate is a yellow to orange powder with a pKa of 8.95. The solubility of sunitinib malate in aqueous media over the range pH 1.2 to pH 6.8 is in excess of 25 mg/mL. The log of the distribution coefficient (octanol/water) at pH 7 is 5.2.
SUTENT (sunitinib malate) capsules are supplied as printed hard shell capsules containing sunitinib malate equivalent to 12.5 mg, 25 mg or 50 mg of sunitinib together with mannitol, croscarmellose sodium, povidone (K-25) and magnesium stearate as inactive ingredients.
The orange gelatin capsule shells contain titanium dioxide, and red iron oxide. The caramel gelatin capsule shells also contain yellow iron oxide and black iron oxide. The printing ink contains shellac, propylene glycol, sodium hydroxide, povidone and titanium dioxide.
Last reviewed on RxList: 8/24/2009





Other reviews about Sutent on wordpress

IPO FILING: Adnexus Therapeutics, Targeting Avastin (ADNX, BMY)
  by 247wallst
ADNEXUS THERAPEUTICS, INC. has filed to come public via an IPO with the filed amount to sell up to $86,250,000 in common stock.  Adnexus has taken the proposed […]


Sunitinib (Sutent) in Metastatic Breast Cancer and Triple-Negative (ER-,PR-, and Her-2-negative) Breast Cancer
  by bmirtsching
Breast cancers that do not contain growth regulator proteins for estrogen receptor (ER), progesterone receptor (PR), or HER-2 are termed “triple negative” tumors. Triple negative tumors are aggressive. […]


Sunitinib (Sutent) for Metastatic Renal (Kidney) Cancer
  by bmirtsching
Recent studies of sunitinib (Sutent) in patients with metastatic renal cell carcinoma have demonstrated it is effective in prolonging disease control and survival. The FDA-approved dosing regimen for […]


Cancer Patients Not Getting New Drug
  by Astrid
Recently, a man in the UK, Alex Baxter, killed himself after being denied a new, likely effective (as in, life-prolonging and quality-enhancing) but very expensive cancer drug, Sutent. […]


Pfizer's Sutent Is Recommended As First-Line Treatment For Kidney Cancer Patients By British Health Agency
  by enartion
Pfizer Inc said that the United Kingdom's National Institute for Health and Clinical Excellence (NICE) has issued its final appraisal document (FAD) recommending the use of Sutent (sunitinib […]


Pfizer's Sutent Scores Another Pancreatic Tumor Win (PFE)
  by 247wallst
Pfizer Inc. (NYSE: PFE) is stopping its Phase III clinical trial of Sutent early.  This is generally a scare over adverse events, but not in this case.  Sutent […]


Today's Top Three in Pharma 060209
  by Steve Woodruff
Sepracor's experimental epilepsy drug (Stedesa) proceeds to FDA review. STEDESA, a new chemical entity, is a novel voltage-gated sodium channel blocker. […]


Impactiviti Daily 102510
  by Steve Woodruff
TODAY’S NEWS Pfizer's oncology drug Sutent slows down pancreatic cancer spread - Pfizer Inc.  said Sutent, its drug for kidney cancer, also helps stop the progression of a […]


CT scan timing and targeted therapy (in my case sutent)
  by drkens
My most recent CT scan was done last week during  the end of my week off of Sutent. This is the first time it was done during the […]


My one year anniversary of taking Sutent
  by drkens
I am more than pleased to report that I have just completed my first year on sutent. I am on a 2 week on/1 week off schedule. Although […]



Other reviews about Sutent on web:

Official site and information about using the drug in treatment for advanced renal cell carcinoma and gastrointestinal stromal tumor (GIST). Official SUTENT® site


Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved ... Sunitinib - Wikipedia, the free encyclopedia


Sutent is a chemotherapy drug that is classified as a targeted therapy and receptor protein-tyrosine kinase inhibitor. Sutent inhibits the actions of vascular endothelial ... Sutent, Sunitinib, SU11248 - Chemotherapy Drugs, Chemo Drug Side ...


Accurate, FDA approved Sutent information for healthcare professionals and patients - brought to you by Drugs.com. Sutent Official FDA information, side effects and uses.


Learn about the prescription medication Sutent (Sunitinib Malate), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Sutent (Sunitinib Malate) Drug Information: Uses, Side Effects ...


SUTENT is used to treat advanced kidney cancer (advanced renal cell carcinoma or RCC). Official SUTENT® site—About RCC


All about Sutent. View complete and up to date Sutent information - part of the Drugs.com trusted medication database. Sutent Facts and Comparisons at Drugs.com


The Life Raft Group. A patient/caregiver support group for GIST cancer. All About Sutent


Buy Sutent (Sunitinib Malate) from our Canadian Online Pharmacy by calling 1-877-888-3562. Fully licensed, fast delivery, free doctor consultation provided. Buy Sutent (Sunitinib Malate) Online Now


HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SUTENT safely and effectively. See full prescribing information for SUTENT. HIGHLIGHTS OF PRESCRIBING INFORMATION





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