Reviews Supprelin LA


No reviews yet.

Supprelin LA Drug Description
Supprelin LA
(histrelin acetate) Subcutaneous Implant
DRUG DESCRIPTION



What are the possible side effects of histrelin (Supprelin LA, Vantas)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

severe numbness or tingling in your legs or feet;
muscle weakness, problems with balance or coordination;
loss of bladder or bowel control;
urinating more or less than usual, or not at all;
fast or pounding...
Read All Potential Side Effects for Supprelin LA »




Supprelin LA (histrelin acetate) subcutaneous implant contains a synthetic
nonapeptide analog of the naturally occurring gonadotropin releasing hormone
(GnRH) that possesses a greater potency than the natural sequence hormone. The
chemical name of histrelin acetate is:
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline
Nethylamide, acetate salt.
The molecular formula for histrelin acetate is C66H86N18O12 x 2 CH3COOH and
its molecular weight is 1443.70 (or 1323.52 as free base). Histrelin is also
chemically described as 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-Lseryl- L-tyrosyl-Nt-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
diacetate. The chemical structure of the free base (histrelin) is represented
below in Figure 1.
Figure 1. Structure of histrelin







The Supprelin LA implant looks like a small thin flexible tube. The sterile
implant consists of a 50-mg histrelin acetate drug core inside a non-biodegradable,
3.5 cm by 3 mm, cylindrical hydrogel reservoir (Figure 2).
Figure 2. Histrelin Implant diagram (not to scale)







The drug core also contains the inactive ingredient stearic acid NF. The hydrogel
reservoir is a cartridge composed of 2-hydroxyethyl methacrylate, 2-hydroxypropyl
methacrylate, trimethylolpropane trimethacrylate, benzoin methyl ether, Perkadox-16,
and Triton X-100. Each hydrated implant is packaged in a glass vial containing
2 mL of 1.8% sodium chloride, sterile solution, so that it is primed for immediate
release of the drug upon insertion. The 3.5 mL Type I clear glass vial with
the implant is closed with a pre-treated grey Teflon coated stopper and sealed
with an aluminum crimp seal.
A single use sterile insertion tool (Trocar) is to be used with Supprelin LA.
The insertion tool is enclosed in a sterile bag as part of the implantation
kit.Last reviewed on RxList: 8/5/2008




Supprelin LA Drug Description
Supprelin LA
(histrelin acetate) Subcutaneous Implant
DRUG DESCRIPTION



What are the possible side effects of histrelin (Supprelin LA, Vantas)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

severe numbness or tingling in your legs or feet;
muscle weakness, problems with balance or coordination;
loss of bladder or bowel control;
urinating more or less than usual, or not at all;
fast or pounding...
Read All Potential Side Effects for Supprelin LA »




Supprelin LA (histrelin acetate) subcutaneous implant contains a synthetic
nonapeptide analog of the naturally occurring gonadotropin releasing hormone
(GnRH) that possesses a greater potency than the natural sequence hormone. The
chemical name of histrelin acetate is:
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline
Nethylamide, acetate salt.
The molecular formula for histrelin acetate is C66H86N18O12 x 2 CH3COOH and
its molecular weight is 1443.70 (or 1323.52 as free base). Histrelin is also
chemically described as 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-Lseryl- L-tyrosyl-Nt-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
diacetate. The chemical structure of the free base (histrelin) is represented
below in Figure 1.
Figure 1. Structure of histrelin







The Supprelin LA implant looks like a small thin flexible tube. The sterile
implant consists of a 50-mg histrelin acetate drug core inside a non-biodegradable,
3.5 cm by 3 mm, cylindrical hydrogel reservoir (Figure 2).
Figure 2. Histrelin Implant diagram (not to scale)







The drug core also contains the inactive ingredient stearic acid NF. The hydrogel
reservoir is a cartridge composed of 2-hydroxyethyl methacrylate, 2-hydroxypropyl
methacrylate, trimethylolpropane trimethacrylate, benzoin methyl ether, Perkadox-16,
and Triton X-100. Each hydrated implant is packaged in a glass vial containing
2 mL of 1.8% sodium chloride, sterile solution, so that it is primed for immediate
release of the drug upon insertion. The 3.5 mL Type I clear glass vial with
the implant is closed with a pre-treated grey Teflon coated stopper and sealed
with an aluminum crimp seal.
A single use sterile insertion tool (Trocar) is to be used with Supprelin LA.
The insertion tool is enclosed in a sterile bag as part of the implantation
kit.Last reviewed on RxList: 8/5/2008




Supprelin LA Drug Description
Supprelin LA
(histrelin acetate) Subcutaneous Implant
DRUG DESCRIPTION



What are the possible side effects of histrelin (Supprelin LA, Vantas)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

severe numbness or tingling in your legs or feet;
muscle weakness, problems with balance or coordination;
loss of bladder or bowel control;
urinating more or less than usual, or not at all;
fast or pounding...
Read All Potential Side Effects for Supprelin LA »




Supprelin LA (histrelin acetate) subcutaneous implant contains a synthetic
nonapeptide analog of the naturally occurring gonadotropin releasing hormone
(GnRH) that possesses a greater potency than the natural sequence hormone. The
chemical name of histrelin acetate is:
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline
Nethylamide, acetate salt.
The molecular formula for histrelin acetate is C66H86N18O12 x 2 CH3COOH and
its molecular weight is 1443.70 (or 1323.52 as free base). Histrelin is also
chemically described as 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-Lseryl- L-tyrosyl-Nt-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
diacetate. The chemical structure of the free base (histrelin) is represented
below in Figure 1.
Figure 1. Structure of histrelin







The Supprelin LA implant looks like a small thin flexible tube. The sterile
implant consists of a 50-mg histrelin acetate drug core inside a non-biodegradable,
3.5 cm by 3 mm, cylindrical hydrogel reservoir (Figure 2).
Figure 2. Histrelin Implant diagram (not to scale)







The drug core also contains the inactive ingredient stearic acid NF. The hydrogel
reservoir is a cartridge composed of 2-hydroxyethyl methacrylate, 2-hydroxypropyl
methacrylate, trimethylolpropane trimethacrylate, benzoin methyl ether, Perkadox-16,
and Triton X-100. Each hydrated implant is packaged in a glass vial containing
2 mL of 1.8% sodium chloride, sterile solution, so that it is primed for immediate
release of the drug upon insertion. The 3.5 mL Type I clear glass vial with
the implant is closed with a pre-treated grey Teflon coated stopper and sealed
with an aluminum crimp seal.
A single use sterile insertion tool (Trocar) is to be used with Supprelin LA.
The insertion tool is enclosed in a sterile bag as part of the implantation
kit.Last reviewed on RxList: 8/5/2008




Supprelin LA Drug Description
Supprelin LA
(histrelin acetate) Subcutaneous Implant
DRUG DESCRIPTION



What are the possible side effects of histrelin (Supprelin LA, Vantas)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

severe numbness or tingling in your legs or feet;
muscle weakness, problems with balance or coordination;
loss of bladder or bowel control;
urinating more or less than usual, or not at all;
fast or pounding...
Read All Potential Side Effects for Supprelin LA »




Supprelin LA (histrelin acetate) subcutaneous implant contains a synthetic
nonapeptide analog of the naturally occurring gonadotropin releasing hormone
(GnRH) that possesses a greater potency than the natural sequence hormone. The
chemical name of histrelin acetate is:
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline
Nethylamide, acetate salt.
The molecular formula for histrelin acetate is C66H86N18O12 x 2 CH3COOH and
its molecular weight is 1443.70 (or 1323.52 as free base). Histrelin is also
chemically described as 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-Lseryl- L-tyrosyl-Nt-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
diacetate. The chemical structure of the free base (histrelin) is represented
below in Figure 1.
Figure 1. Structure of histrelin







The Supprelin LA implant looks like a small thin flexible tube. The sterile
implant consists of a 50-mg histrelin acetate drug core inside a non-biodegradable,
3.5 cm by 3 mm, cylindrical hydrogel reservoir (Figure 2).
Figure 2. Histrelin Implant diagram (not to scale)







The drug core also contains the inactive ingredient stearic acid NF. The hydrogel
reservoir is a cartridge composed of 2-hydroxyethyl methacrylate, 2-hydroxypropyl
methacrylate, trimethylolpropane trimethacrylate, benzoin methyl ether, Perkadox-16,
and Triton X-100. Each hydrated implant is packaged in a glass vial containing
2 mL of 1.8% sodium chloride, sterile solution, so that it is primed for immediate
release of the drug upon insertion. The 3.5 mL Type I clear glass vial with
the implant is closed with a pre-treated grey Teflon coated stopper and sealed
with an aluminum crimp seal.
A single use sterile insertion tool (Trocar) is to be used with Supprelin LA.
The insertion tool is enclosed in a sterile bag as part of the implantation
kit.Last reviewed on RxList: 8/5/2008




Supprelin LA Drug Description
Supprelin LA
(histrelin acetate) Subcutaneous Implant
DRUG DESCRIPTION



What are the possible side effects of histrelin (Supprelin LA, Vantas)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

severe numbness or tingling in your legs or feet;
muscle weakness, problems with balance or coordination;
loss of bladder or bowel control;
urinating more or less than usual, or not at all;
fast or pounding...
Read All Potential Side Effects for Supprelin LA »




Supprelin LA (histrelin acetate) subcutaneous implant contains a synthetic
nonapeptide analog of the naturally occurring gonadotropin releasing hormone
(GnRH) that possesses a greater potency than the natural sequence hormone. The
chemical name of histrelin acetate is:
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-N-benzyl-D-histidyl-L-leucyl-L-arginyl-L-proline
Nethylamide, acetate salt.
The molecular formula for histrelin acetate is C66H86N18O12 x 2 CH3COOH and
its molecular weight is 1443.70 (or 1323.52 as free base). Histrelin is also
chemically described as 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-Lseryl- L-tyrosyl-Nt-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
diacetate. The chemical structure of the free base (histrelin) is represented
below in Figure 1.
Figure 1. Structure of histrelin







The Supprelin LA implant looks like a small thin flexible tube. The sterile
implant consists of a 50-mg histrelin acetate drug core inside a non-biodegradable,
3.5 cm by 3 mm, cylindrical hydrogel reservoir (Figure 2).
Figure 2. Histrelin Implant diagram (not to scale)







The drug core also contains the inactive ingredient stearic acid NF. The hydrogel
reservoir is a cartridge composed of 2-hydroxyethyl methacrylate, 2-hydroxypropyl
methacrylate, trimethylolpropane trimethacrylate, benzoin methyl ether, Perkadox-16,
and Triton X-100. Each hydrated implant is packaged in a glass vial containing
2 mL of 1.8% sodium chloride, sterile solution, so that it is primed for immediate
release of the drug upon insertion. The 3.5 mL Type I clear glass vial with
the implant is closed with a pre-treated grey Teflon coated stopper and sealed
with an aluminum crimp seal.
A single use sterile insertion tool (Trocar) is to be used with Supprelin LA.
The insertion tool is enclosed in a sterile bag as part of the implantation
kit.Last reviewed on RxList: 8/5/2008





Other reviews about Supprelin LA on wordpress

Indevus Buyout of Valera to Grow Earnings
  by 247wallst
From BioHealth InvestorsIndevus Pharmaceuticals (IDEV) just announced it was purchasing Valera Pharmaceuticals (VLRX). News of the $120M acquisition sent IDEV down 7%, and pushed VLRX up 60%. VLRX […]


Data Feed
  by misstrade
08:33 ASFI Asta Funding beats on EPS, beats on revs (27.26 ) Reports Q4 (Sep) earnings of $0.88 per share, includes impairment charges of $6.7 mln, may […]


Indevus Pharmaceuticals Announces PRO 2000 Found To Show Promise In Large HIV Prevention Study
  by enartion
Indevus Pharmaceuticals, Inc. (Nasdaq: IDEV) announced that a National Institutes of Health (NIH)-sponsored clinical study found that participating women who received PRO 2000, the Company's candidate vaginal […]


And if de bees wake, it doa
  by wjzeymwbhjkcfxj
It was then that Keith saw something on the table which had not been there before. Much he cares about the hermit! Even the Indians did not travel […]


And how did you dry yourself?
  by fpsvedjdwc
19:12 His troops come together, and raise up their way against me, and encamp round about my tabernacle. , page 214: The reproductive organs of phoenogams, as is […]



Other reviews about Supprelin LA on web:

Welcome to the official website of SUPPRELIN LA. Get important information about the indications, use, and history of SUPPRELIN LA. SUPPRELIN® LA Official Site – SUPPRELIN LA (histrelin acetate ...


Supprelin-LA (histrelin) is used to treat precocious puberty in both male and female children. Includes Supprelin-LA side effects, interactions and indications. Supprelin-LA Information from Drugs.com


Welcome to the official website of SUPPRELIN LA. Get important information about the indications, use, and history of SUPPRELIN LA. SUPPRELIN® LA Official Site – About SUPPRELIN LA


Learn about the prescription medication Supprelin LA (Histrelin Acetate Subcutaneous Implant), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Supprelin LA (Histrelin Acetate Subcutaneous Implant) Drug ...


Supprelin-LA information from Drugs.com, includes Supprelin-LA side effects, interactions, indications Valera Pharmaceuticals Submits NDA for Supprelin-LA


SUPPRELIN ® LA. This product information is intended for U.S. residents only. SUPPRELIN ® LA (histrelin acetate is a gonadotropin releasing hormone (GnRH) agonist indicated ... Endo Pharmaceuticals


Supprelin-LA would prove to be the remarkable medication therapy in treating the CPP by providing the faster and continual suppression of hormone levels Supprelin-LA for treatment of Central Precocious Puberty


Drug information and side-effects for Supprelin LA (histrelin acetate) Supprelin LA (histrelin acetate) - Drug information from MediLexicon


Organized by therapeutic area, this comprehensive listing of FDA-Approved Drugs by the Food and Drug Administration features facts on clinical trial results, side effects and ... Newly Approved Drug Therapies (950) Supprelin LA (histrelin ...


What is Supprelin LA (Histrelin)? Histrelin is a man-made form of a hormone that regulates many processes in the body. Histrelin overstimulates the body's own production of ... Supprelin LA - Drugs & Treatments - Revolution Health





Featured Reviews

Reviews Fenoprofen Calcium

Nalfon Drug Description NALFON® (fenoprofen calcium) Capsules, USP 200 mg and 400 mg Cardiovascular Risk NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which...
Read More  |  Review This
Reviews Atrovent Nasal Spray

Atrovent Nasal Spray Drug Description Atrovent (ipratropium bromide) Nasal Spray 0.03% DRUG DESCRIPTION What are the possible side effects of ipratropium nasal (Atrovent Nasal)? Stop using ipratropium nasal and get emergency...
Read More  |  Review This
Reviews Nilotinib Capsules

Tasigna Capsules Drug Description Tasigna® (nilotinib) Capsules WARNING QT PROLONGATION AND SUDDEN DEATHS Tasigna prolongs the QT interval. Sudden deaths have been reported in patients receiving nilotinib. Tasigna should not be...
Read More  |  Review This
Reviews Solifenacin Succinate

VESIcare Drug Description VESIcare® (solifenacin succinate) Tablets DRUG DESCRIPTION What are the possible side effects of solifenacin (VESIcare)? Get emergency medical help if you have any of these signs of an allergic reaction:...
Read More  |  Review This
Reviews Prinzide

Prinzide Drug Description PRINZIDE® (lisinopril-hydrochlorothiazide) Tablets USE IN PREGNANCY When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus....
Read More  |  Review This
Recent News
59sec - the BEST lead management system around!
We tested 59sec - THE lead management system and we love it. 59sec helps small and medium companies to answer leads in maximum 59 seconds. Why...
MOVEorPAY - our favorite facebook app
We do love MOVEorPAY motivational facebook app, because it is very cool and useful. It makes you finish stuff that you know are good for you, but from various reasons, you never do...
ReviewsAZ is almost ready to be officially launched
yes, we have just a few loose ends to tie and we are ready to go :) meanwhile, I am putting some reviews on the site, so people will not get an empty site at the launch....