Reviews Sterile Hemofiltration Hemodiafiltration Solution


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PrismaSol Solution Drug Description
PrismaSol Solution
PrismaSol BGK 4/2.5
PrismaSol BGK 4/0/1.2
PrismaSol BK 0/0/1.2
PrismaSol BGK 2/3.5
PrismaSol BGK 2/0
PrismaSol BK 0/3.5
PrismaSol BGK 0/2.5
PrismaSol B22GK 4/0
PrismaSol B22GK 4/2.5
PrismaSol B22GK 2/0
Sterile Hemofitration and Hemodiafiltration Solution
DRUG DESCRIPTION
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins.
This solution is used in Continuous Renal Replacement Therapies (CRRT) as a
replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol solution is packaged in a two-compartment bag. The small compartment
A contains electrolytes and the large compartment B contains buffer. The final
reconstituted solution (5000 mL) is obtained after breaking the red frangible
pin between compartments A and B and mixing both solutions. The compositions
of the solution before and after reconstitution are described in the following
tables.
BEFORE RECONSTITUTION
1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Calcium chloride•2H2O
3.68
5.15
3.68
3.68


Magnesium chloride•6H2O
3.05
2.03
3.05
3.05


Dextrose anhydrous
20.0
20.0
20.0
20.0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0


Lactic acid
5.40
5.40
5.40
5.40



1000mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Sodium chloride
6.46
6.46
6.46
7 .07


Sodium bicarbonate
3.09
3.09
3.09
2.21


Potassium chloride
0.314
0.157
0
0.314



1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium chloride•2H2O
0
0
0
0
0
5.15


Magnesium chloride•6H2O
2.44
2.03
3.05
3.05
2.44
2.03


Dextrose anhydrous
20.0
20.0
20.0
20.0
0
0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0
0
0


Lactic acid
5.40
5.40
5.40
5.40
5.40
5.40



1000 mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Sodium chloride
6.46
6.46
7.07
7.07
6.46
6.46


Sodium bicarbonate
3.09
3.09
2.21
2.21
3.09
3.09


Potassium chloride
0.314
0.157
0.314
0.157
0
0



AFTER RECONSTITUTION of compartments A and B
1000 mL of the reconstituted solution contains



in mEq/L except where noted
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


CalciumCa2+
2.5
3.5
2.5
2.5


Bicarbonate HCO3
32
32
32
22


Potassium K+
4.0
2.0
0
4.0


Magnesium Mg2+
1.5
1.0
1.5
1.5


Sodium Na+
140
140
140
1140


Chloride Cl
113
111.5
109
123


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical
300 mOsm/L
296 mOsm/L
292 mOsm/L
300 mOsm/L






in mEq/L except where noted
PrismaSol
BGK 4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0


Calcium Ca2+
0
0
0
0


Bicarbonate HCO3
32
32
22
22


Potassium K+
4.0
2.0
4.0
2.0


Magnesium Mg2+
1.2
1.0
1.5
1.5


Sodium Na+
140
140
140
140


Chloride Cl
110.2
108
120.5
118.5


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical Osmolarity
295 mOsm/L
295 mOsm/L
295 mOsm/L
295 mOsm/L






In mEq/L except where noted
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium Ca2+
0
3.5


Bicarbonate HCO3
32
32


Potassium K+
0
0


Magnesium Mg2+
1.2
1.0


Sodium Na+
140
140


Chloride Cl
,106.2
109.5


Lactate
3.0
3.0


Dextrose
0
0


Theoretical Osmolarity
282 mOsm/L
287 mOsm/L



Calcium chloride, USP, is chemically designated calcium chloride dihydrate
(CaCl2•2 H2O).
Magnesium chloride, USP, is chemically designated magnesium chloride hexahydrate
(MgCl2•6H2O).
Dextrose, USP, is chemically designated D-Glucose anhydrous (C6H12O6)
or D-Glucose monohydrate (C6H12O6•H2O).
Lactic acid, USP, is chemically designated CH3CH(OH)COOH.
Sodium chloride, USP, is chemically designated NaCl.
Potassium chloride, USP, is chemically designated KCl.
Sodium bicarbonate, USP, is chemically designated NaHCO3.
The pH of the final solution is in the range of 7.0 to 8.5.
Solutions in contact with the plastic container can leach out certain of its
chemical components in very small amounts within the expiration period, e.g.
di 2-ethylhexyl phthalate (DEHP), up to 3 parts per milion; however, the safety
of the plastic has been confirmed in tests in animals according to USP biological
tests for plastic containers as well as by in-vitro toxicity studies.Last reviewed on RxList: 12/29/2008




PrismaSol Solution Drug Description
PrismaSol Solution
PrismaSol BGK 4/2.5
PrismaSol BGK 4/0/1.2
PrismaSol BK 0/0/1.2
PrismaSol BGK 2/3.5
PrismaSol BGK 2/0
PrismaSol BK 0/3.5
PrismaSol BGK 0/2.5
PrismaSol B22GK 4/0
PrismaSol B22GK 4/2.5
PrismaSol B22GK 2/0
Sterile Hemofitration and Hemodiafiltration Solution
DRUG DESCRIPTION
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins.
This solution is used in Continuous Renal Replacement Therapies (CRRT) as a
replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol solution is packaged in a two-compartment bag. The small compartment
A contains electrolytes and the large compartment B contains buffer. The final
reconstituted solution (5000 mL) is obtained after breaking the red frangible
pin between compartments A and B and mixing both solutions. The compositions
of the solution before and after reconstitution are described in the following
tables.
BEFORE RECONSTITUTION
1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Calcium chloride•2H2O
3.68
5.15
3.68
3.68


Magnesium chloride•6H2O
3.05
2.03
3.05
3.05


Dextrose anhydrous
20.0
20.0
20.0
20.0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0


Lactic acid
5.40
5.40
5.40
5.40



1000mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Sodium chloride
6.46
6.46
6.46
7 .07


Sodium bicarbonate
3.09
3.09
3.09
2.21


Potassium chloride
0.314
0.157
0
0.314



1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium chloride•2H2O
0
0
0
0
0
5.15


Magnesium chloride•6H2O
2.44
2.03
3.05
3.05
2.44
2.03


Dextrose anhydrous
20.0
20.0
20.0
20.0
0
0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0
0
0


Lactic acid
5.40
5.40
5.40
5.40
5.40
5.40



1000 mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Sodium chloride
6.46
6.46
7.07
7.07
6.46
6.46


Sodium bicarbonate
3.09
3.09
2.21
2.21
3.09
3.09


Potassium chloride
0.314
0.157
0.314
0.157
0
0



AFTER RECONSTITUTION of compartments A and B
1000 mL of the reconstituted solution contains



in mEq/L except where noted
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


CalciumCa2+
2.5
3.5
2.5
2.5


Bicarbonate HCO3
32
32
32
22


Potassium K+
4.0
2.0
0
4.0


Magnesium Mg2+
1.5
1.0
1.5
1.5


Sodium Na+
140
140
140
1140


Chloride Cl
113
111.5
109
123


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical
300 mOsm/L
296 mOsm/L
292 mOsm/L
300 mOsm/L






in mEq/L except where noted
PrismaSol
BGK 4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0


Calcium Ca2+
0
0
0
0


Bicarbonate HCO3
32
32
22
22


Potassium K+
4.0
2.0
4.0
2.0


Magnesium Mg2+
1.2
1.0
1.5
1.5


Sodium Na+
140
140
140
140


Chloride Cl
110.2
108
120.5
118.5


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical Osmolarity
295 mOsm/L
295 mOsm/L
295 mOsm/L
295 mOsm/L






In mEq/L except where noted
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium Ca2+
0
3.5


Bicarbonate HCO3
32
32


Potassium K+
0
0


Magnesium Mg2+
1.2
1.0


Sodium Na+
140
140


Chloride Cl
,106.2
109.5


Lactate
3.0
3.0


Dextrose
0
0


Theoretical Osmolarity
282 mOsm/L
287 mOsm/L



Calcium chloride, USP, is chemically designated calcium chloride dihydrate
(CaCl2•2 H2O).
Magnesium chloride, USP, is chemically designated magnesium chloride hexahydrate
(MgCl2•6H2O).
Dextrose, USP, is chemically designated D-Glucose anhydrous (C6H12O6)
or D-Glucose monohydrate (C6H12O6•H2O).
Lactic acid, USP, is chemically designated CH3CH(OH)COOH.
Sodium chloride, USP, is chemically designated NaCl.
Potassium chloride, USP, is chemically designated KCl.
Sodium bicarbonate, USP, is chemically designated NaHCO3.
The pH of the final solution is in the range of 7.0 to 8.5.
Solutions in contact with the plastic container can leach out certain of its
chemical components in very small amounts within the expiration period, e.g.
di 2-ethylhexyl phthalate (DEHP), up to 3 parts per milion; however, the safety
of the plastic has been confirmed in tests in animals according to USP biological
tests for plastic containers as well as by in-vitro toxicity studies.Last reviewed on RxList: 12/29/2008




PrismaSol Solution Drug Description
PrismaSol Solution
PrismaSol BGK 4/2.5
PrismaSol BGK 4/0/1.2
PrismaSol BK 0/0/1.2
PrismaSol BGK 2/3.5
PrismaSol BGK 2/0
PrismaSol BK 0/3.5
PrismaSol BGK 0/2.5
PrismaSol B22GK 4/0
PrismaSol B22GK 4/2.5
PrismaSol B22GK 2/0
Sterile Hemofitration and Hemodiafiltration Solution
DRUG DESCRIPTION
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins.
This solution is used in Continuous Renal Replacement Therapies (CRRT) as a
replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol solution is packaged in a two-compartment bag. The small compartment
A contains electrolytes and the large compartment B contains buffer. The final
reconstituted solution (5000 mL) is obtained after breaking the red frangible
pin between compartments A and B and mixing both solutions. The compositions
of the solution before and after reconstitution are described in the following
tables.
BEFORE RECONSTITUTION
1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Calcium chloride•2H2O
3.68
5.15
3.68
3.68


Magnesium chloride•6H2O
3.05
2.03
3.05
3.05


Dextrose anhydrous
20.0
20.0
20.0
20.0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0


Lactic acid
5.40
5.40
5.40
5.40



1000mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Sodium chloride
6.46
6.46
6.46
7 .07


Sodium bicarbonate
3.09
3.09
3.09
2.21


Potassium chloride
0.314
0.157
0
0.314



1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium chloride•2H2O
0
0
0
0
0
5.15


Magnesium chloride•6H2O
2.44
2.03
3.05
3.05
2.44
2.03


Dextrose anhydrous
20.0
20.0
20.0
20.0
0
0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0
0
0


Lactic acid
5.40
5.40
5.40
5.40
5.40
5.40



1000 mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Sodium chloride
6.46
6.46
7.07
7.07
6.46
6.46


Sodium bicarbonate
3.09
3.09
2.21
2.21
3.09
3.09


Potassium chloride
0.314
0.157
0.314
0.157
0
0



AFTER RECONSTITUTION of compartments A and B
1000 mL of the reconstituted solution contains



in mEq/L except where noted
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


CalciumCa2+
2.5
3.5
2.5
2.5


Bicarbonate HCO3
32
32
32
22


Potassium K+
4.0
2.0
0
4.0


Magnesium Mg2+
1.5
1.0
1.5
1.5


Sodium Na+
140
140
140
1140


Chloride Cl
113
111.5
109
123


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical
300 mOsm/L
296 mOsm/L
292 mOsm/L
300 mOsm/L






in mEq/L except where noted
PrismaSol
BGK 4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0


Calcium Ca2+
0
0
0
0


Bicarbonate HCO3
32
32
22
22


Potassium K+
4.0
2.0
4.0
2.0


Magnesium Mg2+
1.2
1.0
1.5
1.5


Sodium Na+
140
140
140
140


Chloride Cl
110.2
108
120.5
118.5


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical Osmolarity
295 mOsm/L
295 mOsm/L
295 mOsm/L
295 mOsm/L






In mEq/L except where noted
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium Ca2+
0
3.5


Bicarbonate HCO3
32
32


Potassium K+
0
0


Magnesium Mg2+
1.2
1.0


Sodium Na+
140
140


Chloride Cl
,106.2
109.5


Lactate
3.0
3.0


Dextrose
0
0


Theoretical Osmolarity
282 mOsm/L
287 mOsm/L



Calcium chloride, USP, is chemically designated calcium chloride dihydrate
(CaCl2•2 H2O).
Magnesium chloride, USP, is chemically designated magnesium chloride hexahydrate
(MgCl2•6H2O).
Dextrose, USP, is chemically designated D-Glucose anhydrous (C6H12O6)
or D-Glucose monohydrate (C6H12O6•H2O).
Lactic acid, USP, is chemically designated CH3CH(OH)COOH.
Sodium chloride, USP, is chemically designated NaCl.
Potassium chloride, USP, is chemically designated KCl.
Sodium bicarbonate, USP, is chemically designated NaHCO3.
The pH of the final solution is in the range of 7.0 to 8.5.
Solutions in contact with the plastic container can leach out certain of its
chemical components in very small amounts within the expiration period, e.g.
di 2-ethylhexyl phthalate (DEHP), up to 3 parts per milion; however, the safety
of the plastic has been confirmed in tests in animals according to USP biological
tests for plastic containers as well as by in-vitro toxicity studies.Last reviewed on RxList: 12/29/2008




PrismaSol Solution Drug Description
PrismaSol Solution
PrismaSol BGK 4/2.5
PrismaSol BGK 4/0/1.2
PrismaSol BK 0/0/1.2
PrismaSol BGK 2/3.5
PrismaSol BGK 2/0
PrismaSol BK 0/3.5
PrismaSol BGK 0/2.5
PrismaSol B22GK 4/0
PrismaSol B22GK 4/2.5
PrismaSol B22GK 2/0
Sterile Hemofitration and Hemodiafiltration Solution
DRUG DESCRIPTION
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins.
This solution is used in Continuous Renal Replacement Therapies (CRRT) as a
replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol solution is packaged in a two-compartment bag. The small compartment
A contains electrolytes and the large compartment B contains buffer. The final
reconstituted solution (5000 mL) is obtained after breaking the red frangible
pin between compartments A and B and mixing both solutions. The compositions
of the solution before and after reconstitution are described in the following
tables.
BEFORE RECONSTITUTION
1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Calcium chloride•2H2O
3.68
5.15
3.68
3.68


Magnesium chloride•6H2O
3.05
2.03
3.05
3.05


Dextrose anhydrous
20.0
20.0
20.0
20.0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0


Lactic acid
5.40
5.40
5.40
5.40



1000mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Sodium chloride
6.46
6.46
6.46
7 .07


Sodium bicarbonate
3.09
3.09
3.09
2.21


Potassium chloride
0.314
0.157
0
0.314



1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium chloride•2H2O
0
0
0
0
0
5.15


Magnesium chloride•6H2O
2.44
2.03
3.05
3.05
2.44
2.03


Dextrose anhydrous
20.0
20.0
20.0
20.0
0
0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0
0
0


Lactic acid
5.40
5.40
5.40
5.40
5.40
5.40



1000 mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Sodium chloride
6.46
6.46
7.07
7.07
6.46
6.46


Sodium bicarbonate
3.09
3.09
2.21
2.21
3.09
3.09


Potassium chloride
0.314
0.157
0.314
0.157
0
0



AFTER RECONSTITUTION of compartments A and B
1000 mL of the reconstituted solution contains



in mEq/L except where noted
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


CalciumCa2+
2.5
3.5
2.5
2.5


Bicarbonate HCO3
32
32
32
22


Potassium K+
4.0
2.0
0
4.0


Magnesium Mg2+
1.5
1.0
1.5
1.5


Sodium Na+
140
140
140
1140


Chloride Cl
113
111.5
109
123


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical
300 mOsm/L
296 mOsm/L
292 mOsm/L
300 mOsm/L






in mEq/L except where noted
PrismaSol
BGK 4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0


Calcium Ca2+
0
0
0
0


Bicarbonate HCO3
32
32
22
22


Potassium K+
4.0
2.0
4.0
2.0


Magnesium Mg2+
1.2
1.0
1.5
1.5


Sodium Na+
140
140
140
140


Chloride Cl
110.2
108
120.5
118.5


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical Osmolarity
295 mOsm/L
295 mOsm/L
295 mOsm/L
295 mOsm/L






In mEq/L except where noted
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium Ca2+
0
3.5


Bicarbonate HCO3
32
32


Potassium K+
0
0


Magnesium Mg2+
1.2
1.0


Sodium Na+
140
140


Chloride Cl
,106.2
109.5


Lactate
3.0
3.0


Dextrose
0
0


Theoretical Osmolarity
282 mOsm/L
287 mOsm/L



Calcium chloride, USP, is chemically designated calcium chloride dihydrate
(CaCl2•2 H2O).
Magnesium chloride, USP, is chemically designated magnesium chloride hexahydrate
(MgCl2•6H2O).
Dextrose, USP, is chemically designated D-Glucose anhydrous (C6H12O6)
or D-Glucose monohydrate (C6H12O6•H2O).
Lactic acid, USP, is chemically designated CH3CH(OH)COOH.
Sodium chloride, USP, is chemically designated NaCl.
Potassium chloride, USP, is chemically designated KCl.
Sodium bicarbonate, USP, is chemically designated NaHCO3.
The pH of the final solution is in the range of 7.0 to 8.5.
Solutions in contact with the plastic container can leach out certain of its
chemical components in very small amounts within the expiration period, e.g.
di 2-ethylhexyl phthalate (DEHP), up to 3 parts per milion; however, the safety
of the plastic has been confirmed in tests in animals according to USP biological
tests for plastic containers as well as by in-vitro toxicity studies.Last reviewed on RxList: 12/29/2008




PrismaSol Solution Drug Description
PrismaSol Solution
PrismaSol BGK 4/2.5
PrismaSol BGK 4/0/1.2
PrismaSol BK 0/0/1.2
PrismaSol BGK 2/3.5
PrismaSol BGK 2/0
PrismaSol BK 0/3.5
PrismaSol BGK 0/2.5
PrismaSol B22GK 4/0
PrismaSol B22GK 4/2.5
PrismaSol B22GK 2/0
Sterile Hemofitration and Hemodiafiltration Solution
DRUG DESCRIPTION
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins.
This solution is used in Continuous Renal Replacement Therapies (CRRT) as a
replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol solution is packaged in a two-compartment bag. The small compartment
A contains electrolytes and the large compartment B contains buffer. The final
reconstituted solution (5000 mL) is obtained after breaking the red frangible
pin between compartments A and B and mixing both solutions. The compositions
of the solution before and after reconstitution are described in the following
tables.
BEFORE RECONSTITUTION
1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Calcium chloride•2H2O
3.68
5.15
3.68
3.68


Magnesium chloride•6H2O
3.05
2.03
3.05
3.05


Dextrose anhydrous
20.0
20.0
20.0
20.0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0


Lactic acid
5.40
5.40
5.40
5.40



1000mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


Sodium chloride
6.46
6.46
6.46
7 .07


Sodium bicarbonate
3.09
3.09
3.09
2.21


Potassium chloride
0.314
0.157
0
0.314



1000 mL of electrolyte solution (small compartment A) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium chloride•2H2O
0
0
0
0
0
5.15


Magnesium chloride•6H2O
2.44
2.03
3.05
3.05
2.44
2.03


Dextrose anhydrous
20.0
20.0
20.0
20.0
0
0


(as dextrose monohydrate)
22.0
22.0
22.0
22.0
0
0


Lactic acid
5.40
5.40
5.40
5.40
5.40
5.40



1000 mL of buffer solution (large compartment B) contains
(g)



 
PrismaSol
BGK4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Sodium chloride
6.46
6.46
7.07
7.07
6.46
6.46


Sodium bicarbonate
3.09
3.09
2.21
2.21
3.09
3.09


Potassium chloride
0.314
0.157
0.314
0.157
0
0



AFTER RECONSTITUTION of compartments A and B
1000 mL of the reconstituted solution contains



in mEq/L except where noted
PrismaSol
BGK 4/2.5
PrismaSol
BGK 2/3.5
PrismaSol
BGK 0/2.5
PrismaSol
B22GK 4/2.5


CalciumCa2+
2.5
3.5
2.5
2.5


Bicarbonate HCO3
32
32
32
22


Potassium K+
4.0
2.0
0
4.0


Magnesium Mg2+
1.5
1.0
1.5
1.5


Sodium Na+
140
140
140
1140


Chloride Cl
113
111.5
109
123


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical
300 mOsm/L
296 mOsm/L
292 mOsm/L
300 mOsm/L






in mEq/L except where noted
PrismaSol
BGK 4/0/1.2
PrismaSol
BGK 2/0
PrismaSol
B22GK 4/0
PrismaSol
B22GK 2/0


Calcium Ca2+
0
0
0
0


Bicarbonate HCO3
32
32
22
22


Potassium K+
4.0
2.0
4.0
2.0


Magnesium Mg2+
1.2
1.0
1.5
1.5


Sodium Na+
140
140
140
140


Chloride Cl
110.2
108
120.5
118.5


Lactate
3.0
3.0
3.0
3.0


Dextrose
100 mg/dL
100 mg/dL
100 mg/dL
100 mg/dL


Theoretical Osmolarity
295 mOsm/L
295 mOsm/L
295 mOsm/L
295 mOsm/L






In mEq/L except where noted
PrismaSol
BK 0/0/1.2
PrismaSol
BK 0/3.5


Calcium Ca2+
0
3.5


Bicarbonate HCO3
32
32


Potassium K+
0
0


Magnesium Mg2+
1.2
1.0


Sodium Na+
140
140


Chloride Cl
,106.2
109.5


Lactate
3.0
3.0


Dextrose
0
0


Theoretical Osmolarity
282 mOsm/L
287 mOsm/L



Calcium chloride, USP, is chemically designated calcium chloride dihydrate
(CaCl2•2 H2O).
Magnesium chloride, USP, is chemically designated magnesium chloride hexahydrate
(MgCl2•6H2O).
Dextrose, USP, is chemically designated D-Glucose anhydrous (C6H12O6)
or D-Glucose monohydrate (C6H12O6•H2O).
Lactic acid, USP, is chemically designated CH3CH(OH)COOH.
Sodium chloride, USP, is chemically designated NaCl.
Potassium chloride, USP, is chemically designated KCl.
Sodium bicarbonate, USP, is chemically designated NaHCO3.
The pH of the final solution is in the range of 7.0 to 8.5.
Solutions in contact with the plastic container can leach out certain of its
chemical components in very small amounts within the expiration period, e.g.
di 2-ethylhexyl phthalate (DEHP), up to 3 parts per milion; however, the safety
of the plastic has been confirmed in tests in animals according to USP biological
tests for plastic containers as well as by in-vitro toxicity studies.Last reviewed on RxList: 12/29/2008





Other reviews about Sterile Hemofiltration Hemodiafiltration Solution on wordpress

PBL: End Stage Renal Disease
  by terrichan
Theme: Love my cheesecake but hate my injections Keywords: 37 y/o woman visited nephrologist history of diabetes (since 15) & […]



Other reviews about Sterile Hemofiltration Hemodiafiltration Solution on web:

Learn about the prescription medication PrismaSol Solution (Sterile Hemofiltration Hemodiafiltration Solution), drug uses, dosage, side effects, drug interactions, warnings ... PrismaSol Solution (Sterile Hemofiltration Hemodiafiltration ...


From anevins: RSS Subscribe: Buy Order Sterile Hemofiltration Hemodiafiltration Solution Prismasol Solution Online Cheap Purchase Buy Order Sterile Hemofiltration Hemodiafiltration Solution ...


Use of sterile, pre-packaged substitution fluid ... current economic environment. Continuous hemofiltration (CHF) or hemodiafiltration ... of replacement fluid from dialysis solution. With ... Hemofiltration - Wikipedia, the free encyclopedia


Sterile Hemofiltration and Hemodiafiltration Solution. DESCRIPTION. PrismaSol solution is a clear, sterile solution free of bacterial endotoxins. This solution is used in Continuous ... DESCRIPTION


Use of sterile, pre-packaged substitution fluid ... Continuous hemofiltration (CHF) or hemodiafiltration (CHDF) ... of replacement fluid from dialysis solution. With ... Hemofiltration: Definition from Answers.com


Use of sterile, pre-packaged substitution fluid ... Continuous hemofiltration (CHF) or hemodiafiltration (CHDF) ... of replacement fluid from dialysis solution. With ... Hemofiltration - wikidoc


... mg/dL100 mg/dL100 mg/dL0 0 Theoretical Osmolarity 300 mOsm/L296 mOsm/L292 mOsm/L291 mOsm/L295 mOsm/L292 mOsm/L282 mOsm/L287 mOsm/L Sterile Hemofiltration and Hemodiafiltration Solution ... PrismaSOL® CRRT Replacement Solution


PrismaSol solution is a clear, sterile solution free of bacterial endotoxins ... before use in order to obtain the reconstituted solution suitable for hemofiltration / hemodiafiltration PrismaSol Official FDA information, side effects and uses.


Use of sterile, pre-packaged substitution fluid ... Continuous hemofiltration (CHF) or hemodiafiltration (CHDF) ... of replacement fluid from dialysis solution.With ... Hemofiltration


... the flow speed of an infusion solution, such as with hemofiltration or hemodiafiltration. ... by one or more bags with sterile infusion solution, such as hemofiltration solution. Method and device for monitoring the flow speed of an infusion ...





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