Reviews Sodium Iodide I 131 Capsules


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Sodium Iodide I 131 Drug Description
SODIUM IODIDE I 131
(sodium iodide, i-131) Capsule
DRUG DESCRIPTION
Sodium Iodide 131 (Na 131I) for diagnostic use is
supplied for oral administration in opaque white gelatin capsules. The capsules
are available in a strength of 3.7 megabecquerels (100 microcuries) iodine
I-131 at the time of calibration.
Sodium Iodide I 131 Capsules are prepared by absorbing a
solution of carrier-free sodium iodide I-131 into inert fillers. The iodine I-131
utilized in the preparation of the capsules contains not less than 99% iodine
I-131 at the time of calibration.
Physical Characteristics
Iodine I-131 decays by beta and associated gamma emissions
with a physical half-life of 8.04 days.1 The principle beta
emissions and gamma photons are listed in Table 1.
Table 1. Principal Radiation Emission Data



Radiation
Mean Percent Per
Disintegration
Energy (keV)


Beta-1
2.12
69.4 Avg.


Beta-3
7.36
96.6 Avg.


Beta-4
89.3
191.6 Avg.


Gamma-7
6.05
284.3


Gamma-14
81.2
364.5


Gamma-17
7.26
637.0




External Radiation
The specific gamma ray constant for iodine I-131 is 2.27
R/hr-mCi at 1 cm. The first half-value thickness of lead (Pb) for iodine I-131 is
0.24 cm. A range of values for the relative attenuation of the radiation
emitted by this radionuclide that results from interposition of various
thicknesses of Pb is shown in Table 2. For example, the use of 4.6 cm of Pb
will decrease the external radiation exposure by a factor of about 1,000.
Table 2. Radiation Attenuation by Lead Shielding*



Shield Thickness (Pb), cm
Coefficient of Attenuation


0.24
0.5


0.95
10-1


2.6
10-2


4.6
10-3


6.5
10-4


*Data supplied by Oak Ridge Associated Universities, Radiopharmaceutical Internal Dose Information Center, Oak Ridge, TN, 1987.




To correct for physical decay of this radionuclide, the
fractions that remain at selected time intervals after the date of calibration
are shown in Table 3.
Table 3. Physical Decay Chart, Iodine I-131, Half Life 8.04 Days



Days
Fraction Remaining
Days
Fraction Remaining


0*
1.000
16
0.252


1
0.917
17
0.231


2
0.842
18
0.212


3
0.772
19
0.194


4
0.708
20
0.178


5
0.650
21
0.164


6
0.596
22
0.150


7
0.547
23
0.138


8
0.502
24
0.126


9
0.460
25
0.116


10
0.422
26
0.106


11
0.387
27
0.098


12
0.355
28
0.089


13
0.326
29
0.082


14
0.299
30
0.075


15
0.274
 
 


*Calibration Day




1Kocher, David C., “Radioactive Decay Data
Tables,” DOE/TIC 11026, page 133 (1981).Last reviewed on RxList: 5/19/2009




Sodium Iodide I 131 Drug Description
SODIUM IODIDE I 131
(sodium iodide, i-131) Capsule
DRUG DESCRIPTION
Sodium Iodide 131 (Na 131I) for diagnostic use is
supplied for oral administration in opaque white gelatin capsules. The capsules
are available in a strength of 3.7 megabecquerels (100 microcuries) iodine
I-131 at the time of calibration.
Sodium Iodide I 131 Capsules are prepared by absorbing a
solution of carrier-free sodium iodide I-131 into inert fillers. The iodine I-131
utilized in the preparation of the capsules contains not less than 99% iodine
I-131 at the time of calibration.
Physical Characteristics
Iodine I-131 decays by beta and associated gamma emissions
with a physical half-life of 8.04 days.1 The principle beta
emissions and gamma photons are listed in Table 1.
Table 1. Principal Radiation Emission Data



Radiation
Mean Percent Per
Disintegration
Energy (keV)


Beta-1
2.12
69.4 Avg.


Beta-3
7.36
96.6 Avg.


Beta-4
89.3
191.6 Avg.


Gamma-7
6.05
284.3


Gamma-14
81.2
364.5


Gamma-17
7.26
637.0




External Radiation
The specific gamma ray constant for iodine I-131 is 2.27
R/hr-mCi at 1 cm. The first half-value thickness of lead (Pb) for iodine I-131 is
0.24 cm. A range of values for the relative attenuation of the radiation
emitted by this radionuclide that results from interposition of various
thicknesses of Pb is shown in Table 2. For example, the use of 4.6 cm of Pb
will decrease the external radiation exposure by a factor of about 1,000.
Table 2. Radiation Attenuation by Lead Shielding*



Shield Thickness (Pb), cm
Coefficient of Attenuation


0.24
0.5


0.95
10-1


2.6
10-2


4.6
10-3


6.5
10-4


*Data supplied by Oak Ridge Associated Universities, Radiopharmaceutical Internal Dose Information Center, Oak Ridge, TN, 1987.




To correct for physical decay of this radionuclide, the
fractions that remain at selected time intervals after the date of calibration
are shown in Table 3.
Table 3. Physical Decay Chart, Iodine I-131, Half Life 8.04 Days



Days
Fraction Remaining
Days
Fraction Remaining


0*
1.000
16
0.252


1
0.917
17
0.231


2
0.842
18
0.212


3
0.772
19
0.194


4
0.708
20
0.178


5
0.650
21
0.164


6
0.596
22
0.150


7
0.547
23
0.138


8
0.502
24
0.126


9
0.460
25
0.116


10
0.422
26
0.106


11
0.387
27
0.098


12
0.355
28
0.089


13
0.326
29
0.082


14
0.299
30
0.075


15
0.274
 
 


*Calibration Day




1Kocher, David C., “Radioactive Decay Data
Tables,” DOE/TIC 11026, page 133 (1981).Last reviewed on RxList: 5/19/2009




Sodium Iodide I 131 Drug Description
SODIUM IODIDE I 131
(sodium iodide, i-131) Capsule
DRUG DESCRIPTION
Sodium Iodide 131 (Na 131I) for diagnostic use is
supplied for oral administration in opaque white gelatin capsules. The capsules
are available in a strength of 3.7 megabecquerels (100 microcuries) iodine
I-131 at the time of calibration.
Sodium Iodide I 131 Capsules are prepared by absorbing a
solution of carrier-free sodium iodide I-131 into inert fillers. The iodine I-131
utilized in the preparation of the capsules contains not less than 99% iodine
I-131 at the time of calibration.
Physical Characteristics
Iodine I-131 decays by beta and associated gamma emissions
with a physical half-life of 8.04 days.1 The principle beta
emissions and gamma photons are listed in Table 1.
Table 1. Principal Radiation Emission Data



Radiation
Mean Percent Per
Disintegration
Energy (keV)


Beta-1
2.12
69.4 Avg.


Beta-3
7.36
96.6 Avg.


Beta-4
89.3
191.6 Avg.


Gamma-7
6.05
284.3


Gamma-14
81.2
364.5


Gamma-17
7.26
637.0




External Radiation
The specific gamma ray constant for iodine I-131 is 2.27
R/hr-mCi at 1 cm. The first half-value thickness of lead (Pb) for iodine I-131 is
0.24 cm. A range of values for the relative attenuation of the radiation
emitted by this radionuclide that results from interposition of various
thicknesses of Pb is shown in Table 2. For example, the use of 4.6 cm of Pb
will decrease the external radiation exposure by a factor of about 1,000.
Table 2. Radiation Attenuation by Lead Shielding*



Shield Thickness (Pb), cm
Coefficient of Attenuation


0.24
0.5


0.95
10-1


2.6
10-2


4.6
10-3


6.5
10-4


*Data supplied by Oak Ridge Associated Universities, Radiopharmaceutical Internal Dose Information Center, Oak Ridge, TN, 1987.




To correct for physical decay of this radionuclide, the
fractions that remain at selected time intervals after the date of calibration
are shown in Table 3.
Table 3. Physical Decay Chart, Iodine I-131, Half Life 8.04 Days



Days
Fraction Remaining
Days
Fraction Remaining


0*
1.000
16
0.252


1
0.917
17
0.231


2
0.842
18
0.212


3
0.772
19
0.194


4
0.708
20
0.178


5
0.650
21
0.164


6
0.596
22
0.150


7
0.547
23
0.138


8
0.502
24
0.126


9
0.460
25
0.116


10
0.422
26
0.106


11
0.387
27
0.098


12
0.355
28
0.089


13
0.326
29
0.082


14
0.299
30
0.075


15
0.274
 
 


*Calibration Day




1Kocher, David C., “Radioactive Decay Data
Tables,” DOE/TIC 11026, page 133 (1981).Last reviewed on RxList: 5/19/2009




Sodium Iodide I 131 Drug Description
SODIUM IODIDE I 131
(sodium iodide, i-131) Capsule
DRUG DESCRIPTION
Sodium Iodide 131 (Na 131I) for diagnostic use is
supplied for oral administration in opaque white gelatin capsules. The capsules
are available in a strength of 3.7 megabecquerels (100 microcuries) iodine
I-131 at the time of calibration.
Sodium Iodide I 131 Capsules are prepared by absorbing a
solution of carrier-free sodium iodide I-131 into inert fillers. The iodine I-131
utilized in the preparation of the capsules contains not less than 99% iodine
I-131 at the time of calibration.
Physical Characteristics
Iodine I-131 decays by beta and associated gamma emissions
with a physical half-life of 8.04 days.1 The principle beta
emissions and gamma photons are listed in Table 1.
Table 1. Principal Radiation Emission Data



Radiation
Mean Percent Per
Disintegration
Energy (keV)


Beta-1
2.12
69.4 Avg.


Beta-3
7.36
96.6 Avg.


Beta-4
89.3
191.6 Avg.


Gamma-7
6.05
284.3


Gamma-14
81.2
364.5


Gamma-17
7.26
637.0




External Radiation
The specific gamma ray constant for iodine I-131 is 2.27
R/hr-mCi at 1 cm. The first half-value thickness of lead (Pb) for iodine I-131 is
0.24 cm. A range of values for the relative attenuation of the radiation
emitted by this radionuclide that results from interposition of various
thicknesses of Pb is shown in Table 2. For example, the use of 4.6 cm of Pb
will decrease the external radiation exposure by a factor of about 1,000.
Table 2. Radiation Attenuation by Lead Shielding*



Shield Thickness (Pb), cm
Coefficient of Attenuation


0.24
0.5


0.95
10-1


2.6
10-2


4.6
10-3


6.5
10-4


*Data supplied by Oak Ridge Associated Universities, Radiopharmaceutical Internal Dose Information Center, Oak Ridge, TN, 1987.




To correct for physical decay of this radionuclide, the
fractions that remain at selected time intervals after the date of calibration
are shown in Table 3.
Table 3. Physical Decay Chart, Iodine I-131, Half Life 8.04 Days



Days
Fraction Remaining
Days
Fraction Remaining


0*
1.000
16
0.252


1
0.917
17
0.231


2
0.842
18
0.212


3
0.772
19
0.194


4
0.708
20
0.178


5
0.650
21
0.164


6
0.596
22
0.150


7
0.547
23
0.138


8
0.502
24
0.126


9
0.460
25
0.116


10
0.422
26
0.106


11
0.387
27
0.098


12
0.355
28
0.089


13
0.326
29
0.082


14
0.299
30
0.075


15
0.274
 
 


*Calibration Day




1Kocher, David C., “Radioactive Decay Data
Tables,” DOE/TIC 11026, page 133 (1981).Last reviewed on RxList: 5/19/2009




Sodium Iodide I 131 Drug Description
SODIUM IODIDE I 131
(sodium iodide, i-131) Capsule
DRUG DESCRIPTION
Sodium Iodide 131 (Na 131I) for diagnostic use is
supplied for oral administration in opaque white gelatin capsules. The capsules
are available in a strength of 3.7 megabecquerels (100 microcuries) iodine
I-131 at the time of calibration.
Sodium Iodide I 131 Capsules are prepared by absorbing a
solution of carrier-free sodium iodide I-131 into inert fillers. The iodine I-131
utilized in the preparation of the capsules contains not less than 99% iodine
I-131 at the time of calibration.
Physical Characteristics
Iodine I-131 decays by beta and associated gamma emissions
with a physical half-life of 8.04 days.1 The principle beta
emissions and gamma photons are listed in Table 1.
Table 1. Principal Radiation Emission Data



Radiation
Mean Percent Per
Disintegration
Energy (keV)


Beta-1
2.12
69.4 Avg.


Beta-3
7.36
96.6 Avg.


Beta-4
89.3
191.6 Avg.


Gamma-7
6.05
284.3


Gamma-14
81.2
364.5


Gamma-17
7.26
637.0




External Radiation
The specific gamma ray constant for iodine I-131 is 2.27
R/hr-mCi at 1 cm. The first half-value thickness of lead (Pb) for iodine I-131 is
0.24 cm. A range of values for the relative attenuation of the radiation
emitted by this radionuclide that results from interposition of various
thicknesses of Pb is shown in Table 2. For example, the use of 4.6 cm of Pb
will decrease the external radiation exposure by a factor of about 1,000.
Table 2. Radiation Attenuation by Lead Shielding*



Shield Thickness (Pb), cm
Coefficient of Attenuation


0.24
0.5


0.95
10-1


2.6
10-2


4.6
10-3


6.5
10-4


*Data supplied by Oak Ridge Associated Universities, Radiopharmaceutical Internal Dose Information Center, Oak Ridge, TN, 1987.




To correct for physical decay of this radionuclide, the
fractions that remain at selected time intervals after the date of calibration
are shown in Table 3.
Table 3. Physical Decay Chart, Iodine I-131, Half Life 8.04 Days



Days
Fraction Remaining
Days
Fraction Remaining


0*
1.000
16
0.252


1
0.917
17
0.231


2
0.842
18
0.212


3
0.772
19
0.194


4
0.708
20
0.178


5
0.650
21
0.164


6
0.596
22
0.150


7
0.547
23
0.138


8
0.502
24
0.126


9
0.460
25
0.116


10
0.422
26
0.106


11
0.387
27
0.098


12
0.355
28
0.089


13
0.326
29
0.082


14
0.299
30
0.075


15
0.274
 
 


*Calibration Day




1Kocher, David C., “Radioactive Decay Data
Tables,” DOE/TIC 11026, page 133 (1981).Last reviewed on RxList: 5/19/2009





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Other reviews about Sodium Iodide I 131 Capsules on web:

Learn about the prescription medication Sodium Iodide I 131 (Sodium Iodide I 131 Capsules), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Sodium Iodide I 131 (Sodium Iodide I 131 Capsules) Drug ...


Sodium Iodide I-131 Brand names: Iodotope™ Chemical formula: Drug Forms: Sodium Iodide I-131 Therapeutic capsules or solution (below) Sodium Sodium Iodide I-131: Information from Answers.com


Sodium Iodide I-131 Therapeutic capsules or solution To return to the main entry click here . What are Sodium Iodide I-131 therapeutic capsules or Sodium Iodide I-131 Therapeutic capsules or solution: Information ...


Animal reproduction studies have not been conducted with Sodium Iodide I 131 Diagnostic Capsules. It is also not known whether Sodium Iodide I 131 Diagnostic Capsules can cause ... Sodium Iodide I 131 Official FDA information, side effects and uses.


Sodium Iodide I 131 Pronunciation: (So-dee-uhm EYE-uh-dide I ... - Capsules 1 to 50 mCi - Oral Solution 7.05 mCi. Trade Names: Sodium Iodide I 131 Complete Sodium Iodide I 131 information from Drugs.com


Click for larger view MSDS for Sodium Iodide I 131 Capsules Therapeutic Package Insert for Sodium Iodide I 131 Capsules Therapeutic Sodium Iodide I 131 Therapy Capsule Decay-Order ... Sodium Iodide I 131


The present invention relates to radiopharmaceutical products used in the treatment of thyroid diseases. In particular, the present invention relates to sodium Sodium iodide .sup.131 I capsules - US 5314678


The present invention relates to radiopharmaceutical products used in the treatment of thyroid diseases. In particular, the present invention relates to sodium iodide 131 ... Sodium iodide 131 I capsules - Patent 5314678


Sodium Iodide I-131 Diagnostic capsules What are Sodium Iodide I-131 diagnostic capsules? SODIUM IODIDE I-131 is a drug that gives off radiation. Sodium Iodide I-131


PREPARATIONS: Sodium iodide I 131 is available as a capsule containing 0.75-100 millicuries (mCi) of radioactivity per capsule. (A millicurie is a unit for measuring radioactivity. sodium iodide I 131 - Cancer Information (Cancers, Symptoms ...





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