Reviews Sargramostim


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Leukine Drug Description
LEUKINE®
(sargramostim)
DRUG DESCRIPTION



What are the possible side effects of sargramostim (Leukine)?

If you experience any of the following serious side effects, stop using sargramostim and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
dizziness or fainting;
a fever (over 100.5 degrees Fahrenheit or 38 degrees Celsius);
signs of infection including chills, sore throat, or congestion or redness, pain, or swelling around a...
Read All Potential Side Effects for Leukine »




LEUKINE® (sargramostim) is a recombinant human granulocyte macrophage colony
stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a
yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth
factor which stimulates proliferation and differentiation of hematopoietic progenitor
cells. LEUKINE is a glycoprotein of 127 amino acids characterized by three primary
molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons.
The amino acid sequence of LEUKINE differs from the natural human GM-CSF by
a substitution of leucine at position 23, and the carbohydrate moiety may be
different from the native protein. Sargramostim has been selected as the proper
name for yeast derived rhu GM-CSF.
The liquid LEUKINE presentation is formulated as a sterile, preserved (1.1%
benzyl alcohol), injectable solution (500 mcg/mL) in a vial. Lyophilized LEUKINE
is a sterile, white, preservative free powder (250 mcg) that requires reconstitution
with 1 mL Sterile Water for Injection, USP or 1 mL Bacteriostatic Water for
Injection, USP. Liquid LEUKINE has a pH range of 6.7 - 7.7 and lyophilized LEUKINE
has a pH range of 7.1 - 7.7.
Liquid LEUKINE and reconstituted lyophilized LEUKINE are clear, colorless liquids
suitable for subcutaneous injection (SC) or intravenous infusion (IV). Liquid
LEUKINE contains 500 mcg (2.8 x 106 IU/mL) sargramostim and 1.1%
benzyl alcohol in a 1 mL solution. The vial of lyophilized LEUKINE contains
250 mcg (1.4 x 106 IU/vial) sargramostim. The liquid LEUKINE vial
and reconstituted lyophilized LEUKINE vial also contain 40 mg/mL mannitol, USP;
10 mg/mL sucrose, NF; and 1.2 mg/mL tromethamine, USP, as excipients. Biological
potency is expressed in International Units (IU) as tested against the WHO First
International Reference Standard. The specific activity of LEUKINE is approximately
5.6 x 106 IU/mg.Last reviewed on RxList: 8/12/2008




Leukine Drug Description
LEUKINE®
(sargramostim)
DRUG DESCRIPTION



What are the possible side effects of sargramostim (Leukine)?

If you experience any of the following serious side effects, stop using sargramostim and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
dizziness or fainting;
a fever (over 100.5 degrees Fahrenheit or 38 degrees Celsius);
signs of infection including chills, sore throat, or congestion or redness, pain, or swelling around a...
Read All Potential Side Effects for Leukine »




LEUKINE® (sargramostim) is a recombinant human granulocyte macrophage colony
stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a
yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth
factor which stimulates proliferation and differentiation of hematopoietic progenitor
cells. LEUKINE is a glycoprotein of 127 amino acids characterized by three primary
molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons.
The amino acid sequence of LEUKINE differs from the natural human GM-CSF by
a substitution of leucine at position 23, and the carbohydrate moiety may be
different from the native protein. Sargramostim has been selected as the proper
name for yeast derived rhu GM-CSF.
The liquid LEUKINE presentation is formulated as a sterile, preserved (1.1%
benzyl alcohol), injectable solution (500 mcg/mL) in a vial. Lyophilized LEUKINE
is a sterile, white, preservative free powder (250 mcg) that requires reconstitution
with 1 mL Sterile Water for Injection, USP or 1 mL Bacteriostatic Water for
Injection, USP. Liquid LEUKINE has a pH range of 6.7 - 7.7 and lyophilized LEUKINE
has a pH range of 7.1 - 7.7.
Liquid LEUKINE and reconstituted lyophilized LEUKINE are clear, colorless liquids
suitable for subcutaneous injection (SC) or intravenous infusion (IV). Liquid
LEUKINE contains 500 mcg (2.8 x 106 IU/mL) sargramostim and 1.1%
benzyl alcohol in a 1 mL solution. The vial of lyophilized LEUKINE contains
250 mcg (1.4 x 106 IU/vial) sargramostim. The liquid LEUKINE vial
and reconstituted lyophilized LEUKINE vial also contain 40 mg/mL mannitol, USP;
10 mg/mL sucrose, NF; and 1.2 mg/mL tromethamine, USP, as excipients. Biological
potency is expressed in International Units (IU) as tested against the WHO First
International Reference Standard. The specific activity of LEUKINE is approximately
5.6 x 106 IU/mg.Last reviewed on RxList: 8/12/2008




Leukine Drug Description
LEUKINE®
(sargramostim)
DRUG DESCRIPTION



What are the possible side effects of sargramostim (Leukine)?

If you experience any of the following serious side effects, stop using sargramostim and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
dizziness or fainting;
a fever (over 100.5 degrees Fahrenheit or 38 degrees Celsius);
signs of infection including chills, sore throat, or congestion or redness, pain, or swelling around a...
Read All Potential Side Effects for Leukine »




LEUKINE® (sargramostim) is a recombinant human granulocyte macrophage colony
stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a
yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth
factor which stimulates proliferation and differentiation of hematopoietic progenitor
cells. LEUKINE is a glycoprotein of 127 amino acids characterized by three primary
molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons.
The amino acid sequence of LEUKINE differs from the natural human GM-CSF by
a substitution of leucine at position 23, and the carbohydrate moiety may be
different from the native protein. Sargramostim has been selected as the proper
name for yeast derived rhu GM-CSF.
The liquid LEUKINE presentation is formulated as a sterile, preserved (1.1%
benzyl alcohol), injectable solution (500 mcg/mL) in a vial. Lyophilized LEUKINE
is a sterile, white, preservative free powder (250 mcg) that requires reconstitution
with 1 mL Sterile Water for Injection, USP or 1 mL Bacteriostatic Water for
Injection, USP. Liquid LEUKINE has a pH range of 6.7 - 7.7 and lyophilized LEUKINE
has a pH range of 7.1 - 7.7.
Liquid LEUKINE and reconstituted lyophilized LEUKINE are clear, colorless liquids
suitable for subcutaneous injection (SC) or intravenous infusion (IV). Liquid
LEUKINE contains 500 mcg (2.8 x 106 IU/mL) sargramostim and 1.1%
benzyl alcohol in a 1 mL solution. The vial of lyophilized LEUKINE contains
250 mcg (1.4 x 106 IU/vial) sargramostim. The liquid LEUKINE vial
and reconstituted lyophilized LEUKINE vial also contain 40 mg/mL mannitol, USP;
10 mg/mL sucrose, NF; and 1.2 mg/mL tromethamine, USP, as excipients. Biological
potency is expressed in International Units (IU) as tested against the WHO First
International Reference Standard. The specific activity of LEUKINE is approximately
5.6 x 106 IU/mg.Last reviewed on RxList: 8/12/2008




Leukine Drug Description
LEUKINE®
(sargramostim)
DRUG DESCRIPTION



What are the possible side effects of sargramostim (Leukine)?

If you experience any of the following serious side effects, stop using sargramostim and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
dizziness or fainting;
a fever (over 100.5 degrees Fahrenheit or 38 degrees Celsius);
signs of infection including chills, sore throat, or congestion or redness, pain, or swelling around a...
Read All Potential Side Effects for Leukine »




LEUKINE® (sargramostim) is a recombinant human granulocyte macrophage colony
stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a
yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth
factor which stimulates proliferation and differentiation of hematopoietic progenitor
cells. LEUKINE is a glycoprotein of 127 amino acids characterized by three primary
molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons.
The amino acid sequence of LEUKINE differs from the natural human GM-CSF by
a substitution of leucine at position 23, and the carbohydrate moiety may be
different from the native protein. Sargramostim has been selected as the proper
name for yeast derived rhu GM-CSF.
The liquid LEUKINE presentation is formulated as a sterile, preserved (1.1%
benzyl alcohol), injectable solution (500 mcg/mL) in a vial. Lyophilized LEUKINE
is a sterile, white, preservative free powder (250 mcg) that requires reconstitution
with 1 mL Sterile Water for Injection, USP or 1 mL Bacteriostatic Water for
Injection, USP. Liquid LEUKINE has a pH range of 6.7 - 7.7 and lyophilized LEUKINE
has a pH range of 7.1 - 7.7.
Liquid LEUKINE and reconstituted lyophilized LEUKINE are clear, colorless liquids
suitable for subcutaneous injection (SC) or intravenous infusion (IV). Liquid
LEUKINE contains 500 mcg (2.8 x 106 IU/mL) sargramostim and 1.1%
benzyl alcohol in a 1 mL solution. The vial of lyophilized LEUKINE contains
250 mcg (1.4 x 106 IU/vial) sargramostim. The liquid LEUKINE vial
and reconstituted lyophilized LEUKINE vial also contain 40 mg/mL mannitol, USP;
10 mg/mL sucrose, NF; and 1.2 mg/mL tromethamine, USP, as excipients. Biological
potency is expressed in International Units (IU) as tested against the WHO First
International Reference Standard. The specific activity of LEUKINE is approximately
5.6 x 106 IU/mg.Last reviewed on RxList: 8/12/2008




Leukine Drug Description
LEUKINE®
(sargramostim)
DRUG DESCRIPTION



What are the possible side effects of sargramostim (Leukine)?

If you experience any of the following serious side effects, stop using sargramostim and seek emergency medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
dizziness or fainting;
a fever (over 100.5 degrees Fahrenheit or 38 degrees Celsius);
signs of infection including chills, sore throat, or congestion or redness, pain, or swelling around a...
Read All Potential Side Effects for Leukine »




LEUKINE® (sargramostim) is a recombinant human granulocyte macrophage colony
stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a
yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth
factor which stimulates proliferation and differentiation of hematopoietic progenitor
cells. LEUKINE is a glycoprotein of 127 amino acids characterized by three primary
molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons.
The amino acid sequence of LEUKINE differs from the natural human GM-CSF by
a substitution of leucine at position 23, and the carbohydrate moiety may be
different from the native protein. Sargramostim has been selected as the proper
name for yeast derived rhu GM-CSF.
The liquid LEUKINE presentation is formulated as a sterile, preserved (1.1%
benzyl alcohol), injectable solution (500 mcg/mL) in a vial. Lyophilized LEUKINE
is a sterile, white, preservative free powder (250 mcg) that requires reconstitution
with 1 mL Sterile Water for Injection, USP or 1 mL Bacteriostatic Water for
Injection, USP. Liquid LEUKINE has a pH range of 6.7 - 7.7 and lyophilized LEUKINE
has a pH range of 7.1 - 7.7.
Liquid LEUKINE and reconstituted lyophilized LEUKINE are clear, colorless liquids
suitable for subcutaneous injection (SC) or intravenous infusion (IV). Liquid
LEUKINE contains 500 mcg (2.8 x 106 IU/mL) sargramostim and 1.1%
benzyl alcohol in a 1 mL solution. The vial of lyophilized LEUKINE contains
250 mcg (1.4 x 106 IU/vial) sargramostim. The liquid LEUKINE vial
and reconstituted lyophilized LEUKINE vial also contain 40 mg/mL mannitol, USP;
10 mg/mL sucrose, NF; and 1.2 mg/mL tromethamine, USP, as excipients. Biological
potency is expressed in International Units (IU) as tested against the WHO First
International Reference Standard. The specific activity of LEUKINE is approximately
5.6 x 106 IU/mg.Last reviewed on RxList: 8/12/2008





Other reviews about Sargramostim on wordpress

Leukine (sargramostim)
  by Law Offices of Sadaka Associates
Bayer and FDA informed healthcare professionals of the market withdrawal of the current liquid formulation of Leukine, a growth factor that helps fight infection and disease in appropriate […]


Bayer Announces Upcoming Presentations Of Campath(R) And Leukine(R) Data At The 50th Annual Meeting Of The American Society Of Hematology
  by yestelli
Bayer HealthCare Pharmaceuticals Inc. announced that data on Campath(R) (alemtuzumab) and Leukine(R) (sargramostim) will be presented at the 50th Annual Meeting of the American Society of Hematology (ASH) […]


Bayer Announces Upcoming Presentations Of Campath(R) And Leukine(R) Data At The 50th Annual Meeting Of The American Society Of Hematology
  by healtherm2
Bayer HealthCare Pharmaceuticals Inc. announced that data on Campath(R) (alemtuzumab) and Leukine(R) (sargramostim) will be presented at the 50th Annual Meeting of the American Society of Hematology (ASH) […]


Managing Side Effects
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Quality of Life
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Care for people with blood cancer includes providing good quality of life. Supportive care is given to prevent or treat psychosocial and physical aspects of disease and/or treatment. Psychosocial […]


ASCO 2010 Sunday June 6: Melanoma General Poster Session
  by drericwhitman
I went through the general poster session and selected what I thought were the top 10 posters. I based this loosely on two criteria: innovation and clinical relevance. […]


Breast cancer prophylaxis
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Other reviews about Sargramostim on web:

Sargramostim (marketed by Bayer under the tradename Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as an immunostimulator. Sargramostim - Wikipedia, the free encyclopedia


Leukine (sargramostim) is used to help prevent infection in certain types of cancer therapy. Leukine (sargramostim) - Leukine.com


Sargramostim Key Terms: Antibiotics , Apheresis , Bone marrow transplant , Chemotherapy , Intravenous , Food and Drug Administration , Neutropenia , Sargramostim: Information from Answers.com


Physician reviewed sargramostim patient information - includes sargramostim description, dosage and directions. sargramostim medical facts from Drugs.com


Learn about the prescription medication Leukine (Sargramostim), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Leukine (Sargramostim) Drug Information: Uses, Side Effects, Drug ...


Sargramostim is a biologic response modifier. It is classified as a colony stimulating factor. Leukine, GM-CSF Sargramostim, Leukine, GM-CSF - Chemotherapy Drugs, Chemo Drug ...


Consumer information about the medication SARGRAMOSTIM - INJECTION (Leukine), includes side effects, drug interactions, recommended dosages, and storage information. Read more ... SARGRAMOSTIM - INJECTION (Leukine) side effects, medical uses, and ...


sargramostim /sar·gram·os·tim/ (sahr-gram´o-stim) granulocyte-macrophage colony-stimulating factor developed by recombinant technology; used to enhance neutrophil function ... Sargramostim - definition of Sargramostim in the Medical ...


Information on many different cancers includes symptoms, cancer detection and prevention, and treatment options. sargramostim - Cancer Information (Cancers, Symptoms, Treatment ...


Britannica online encyclopedia article on sargramostim (biology), ... Email " is the e-mail address you used when you registered. " Password" is case sensitive. sargramostim (biology ...





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