Reviews Preservative-Free Heparin Lock Flush Solution


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HEP-LOCK U/P Drug Description
HEP-LOCK U/P
Preservative-Free
(Heparin Lock Flush) Solution, USP
DRUG DESCRIPTION
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides,
called glycosaminoglycans, having anticoagulant properties. Although others
may be present, the main sugars occurring in heparin are: (1) α-L-iduronic
acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid.
These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5),
and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin
is strongly acidic because of its content of covalently linked sulfate and carboxylic
acid groups. In heparin sodium, the acidic protons of the sulfate units are
partially replaced by sodium ions.
Structural formula of Heparin Sodium (representative sub-units):








HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is a sterile
solution for intravenous flush only. It is not to be used for anticoagulant
therapy. HEP-LOCK U/P is specially formulated for use in situations where the
use of preservatives is not advisable. Each mL contains heparin sodium 10 or
100 USP units, derived from porcine intestines and standardized for use as an
anticoagulant, sodium chloride 8 mg, monobasic sodium phosphate monohydrate
2.3 mg, and dibasic sodium phosphate anhydrous 0.5 mg in Water for Injection.
pH 5.0-7.5. The potency is determined by biological assay using a USP reference
standard based on units of heparin activity per milligram.Last reviewed on RxList: 1/26/2009




HEP-LOCK U/P Drug Description
HEP-LOCK U/P
Preservative-Free
(Heparin Lock Flush) Solution, USP
DRUG DESCRIPTION
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides,
called glycosaminoglycans, having anticoagulant properties. Although others
may be present, the main sugars occurring in heparin are: (1) α-L-iduronic
acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid.
These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5),
and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin
is strongly acidic because of its content of covalently linked sulfate and carboxylic
acid groups. In heparin sodium, the acidic protons of the sulfate units are
partially replaced by sodium ions.
Structural formula of Heparin Sodium (representative sub-units):








HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is a sterile
solution for intravenous flush only. It is not to be used for anticoagulant
therapy. HEP-LOCK U/P is specially formulated for use in situations where the
use of preservatives is not advisable. Each mL contains heparin sodium 10 or
100 USP units, derived from porcine intestines and standardized for use as an
anticoagulant, sodium chloride 8 mg, monobasic sodium phosphate monohydrate
2.3 mg, and dibasic sodium phosphate anhydrous 0.5 mg in Water for Injection.
pH 5.0-7.5. The potency is determined by biological assay using a USP reference
standard based on units of heparin activity per milligram.Last reviewed on RxList: 1/26/2009




HEP-LOCK U/P Drug Description
HEP-LOCK U/P
Preservative-Free
(Heparin Lock Flush) Solution, USP
DRUG DESCRIPTION
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides,
called glycosaminoglycans, having anticoagulant properties. Although others
may be present, the main sugars occurring in heparin are: (1) α-L-iduronic
acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid.
These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5),
and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin
is strongly acidic because of its content of covalently linked sulfate and carboxylic
acid groups. In heparin sodium, the acidic protons of the sulfate units are
partially replaced by sodium ions.
Structural formula of Heparin Sodium (representative sub-units):








HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is a sterile
solution for intravenous flush only. It is not to be used for anticoagulant
therapy. HEP-LOCK U/P is specially formulated for use in situations where the
use of preservatives is not advisable. Each mL contains heparin sodium 10 or
100 USP units, derived from porcine intestines and standardized for use as an
anticoagulant, sodium chloride 8 mg, monobasic sodium phosphate monohydrate
2.3 mg, and dibasic sodium phosphate anhydrous 0.5 mg in Water for Injection.
pH 5.0-7.5. The potency is determined by biological assay using a USP reference
standard based on units of heparin activity per milligram.Last reviewed on RxList: 1/26/2009




HEP-LOCK U/P Drug Description
HEP-LOCK U/P
Preservative-Free
(Heparin Lock Flush) Solution, USP
DRUG DESCRIPTION
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides,
called glycosaminoglycans, having anticoagulant properties. Although others
may be present, the main sugars occurring in heparin are: (1) α-L-iduronic
acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid.
These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5),
and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin
is strongly acidic because of its content of covalently linked sulfate and carboxylic
acid groups. In heparin sodium, the acidic protons of the sulfate units are
partially replaced by sodium ions.
Structural formula of Heparin Sodium (representative sub-units):








HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is a sterile
solution for intravenous flush only. It is not to be used for anticoagulant
therapy. HEP-LOCK U/P is specially formulated for use in situations where the
use of preservatives is not advisable. Each mL contains heparin sodium 10 or
100 USP units, derived from porcine intestines and standardized for use as an
anticoagulant, sodium chloride 8 mg, monobasic sodium phosphate monohydrate
2.3 mg, and dibasic sodium phosphate anhydrous 0.5 mg in Water for Injection.
pH 5.0-7.5. The potency is determined by biological assay using a USP reference
standard based on units of heparin activity per milligram.Last reviewed on RxList: 1/26/2009




HEP-LOCK U/P Drug Description
HEP-LOCK U/P
Preservative-Free
(Heparin Lock Flush) Solution, USP
DRUG DESCRIPTION
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides,
called glycosaminoglycans, having anticoagulant properties. Although others
may be present, the main sugars occurring in heparin are: (1) α-L-iduronic
acid 2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose and (5) α-L-iduronic acid.
These sugars are present in decreasing amounts, usually in the order (2) > (1) > (4) > (3) > (5),
and are joined by glycosidic linkages, forming polymers of varying sizes. Heparin
is strongly acidic because of its content of covalently linked sulfate and carboxylic
acid groups. In heparin sodium, the acidic protons of the sulfate units are
partially replaced by sodium ions.
Structural formula of Heparin Sodium (representative sub-units):








HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is a sterile
solution for intravenous flush only. It is not to be used for anticoagulant
therapy. HEP-LOCK U/P is specially formulated for use in situations where the
use of preservatives is not advisable. Each mL contains heparin sodium 10 or
100 USP units, derived from porcine intestines and standardized for use as an
anticoagulant, sodium chloride 8 mg, monobasic sodium phosphate monohydrate
2.3 mg, and dibasic sodium phosphate anhydrous 0.5 mg in Water for Injection.
pH 5.0-7.5. The potency is determined by biological assay using a USP reference
standard based on units of heparin activity per milligram.Last reviewed on RxList: 1/26/2009





Other reviews about Preservative-Free Heparin Lock Flush Solution on wordpress

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Other reviews about Preservative-Free Heparin Lock Flush Solution on web:

Learn about the prescription medication HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution), drug uses, dosage, side effects, drug interactions, warnings, reviews and ... HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution) Drug ...


APP Pharmaceuticals, Inc. announced today that it has received clearance from the U.S. Food and Drug Administration to market preservative-free Heparin Lock Flush Solution in two ... APP Pharmaceuticals Announces Marketing Clearance of Preservative ...


Heparin Lock Flush Solution, USP is a sterile preparation of heparin sodium ... HEPFLUSH®-10 (Heparin Lock Flush Solution, USP, Preservative Free), 10 USP Units/mL, in a 10 ... Hepflush 10 (Heparin Lock Flush Solution) Drug Information: Uses ...


“The FDA clearance to market a preservative-free Heparin Lock Flush Solution provides healthcare professionals with a safer alternative to maintain the patency of ... APP Pharmaceuticals Announces Marketing Clearance of Preservative ...


APP Pharmaceuticals Announces Marketing Clearance of Preservative-Free Heparin Lock Flush Solution, USP Tue Jul 6, 1:01 AM APP Pharmaceuticals Announces Marketing Clearance of Preservative ...


Use in Neonates Preservative-Free Heparin Lock Flush Solution, USP should be used for maintaining the patency of intravenous injection devices in neonates. HEPARIN LOCK FLUSH SOLUTION, USP


"The FDA clearance to market a preservative-free Heparin Lock Flush Solution provides healthcare professionals with a safer alternative to maintain the patency of intravenous ... APP receives FDA marketing clearance for preservative-free Heparin ...


The U.S. Food and Drug Administration has cleared APP Pharmaceuticals to market its preservative-free Heparin Lock Flush Solution, USP in two dosage strengths, 10 USP Units/1 mL ... FDA Clears APP Heparin Lock Flush Solution


Hep-Lock U/P Injection - HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution, USP) is intended to maintain patency ... Hep-Lock U/P Injection drug information | MIMS USA


100 unit/mL preservative-free, 1 mL vial, package of 25 (NDC 00641-0273-25) ... Recall of Heparin Sodium Injection and Heparin Lock Flush Solution (Baxter). Bulletin





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