Reviews Prasugrel Tablets


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Effient Drug Description
EFFIENT
(prasugrel) Tablets

WARNING: BLEEDING RISK
Effient can cause significant, sometimes fatal, bleeding [see WARNINGS
AND PRECAUTIONS and ADVERSE
REACTIONS].
Do not use Effient in patients with active pathological bleeding or a history
of transient ischemic attack or stroke [see CONTRAINDICATIONS].
In patients ≥ 75 years of age, Effient is generally not recommended,
because of the increased risk of fatal and intracranial bleeding and uncertain
benefit, except in high-risk situations (patients with diabetes or a history
of prior MI) where its effect appears to be greater and its use may be considered
[see Use in Specific Populations].
Do not start Effient in patients likely to undergo urgent coronary artery
bypass graft surgery (CABG). When possible, discontinue Effient at least 7 days
prior to any surgery. Additional risk factors for bleeding include:

body weight < 60 kg
propensity to bleed
concomitant use of medications that increase the risk of bleeding (e.g.,
warfarin, heparin, fibrinolytic therapy, chronic use of non-steroidal anti-inflammatory
drugs [NSAIDS])

Suspect bleeding in any patient who is hypotensive and has recently undergone
coronary angiography, percutaneous coronary intervention (PCI), CABG, or other
surgical procedures in the setting of Effient.
If possible, manage bleeding without discontinuing Effient. Discontinuing
Effient, particularly in the first few weeks after acute coronary syndrome,
increases the risk of subsequent cardiovascular events [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of prasugrel (Effient)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;
pale skin, fever, easy bruising, purple or red spots under your skin;
jaundice (yellowing of the skin or eyes);
unexpected vaginal...
Read All Potential Side Effects for Effient »




Effient contains prasugrel, a thienopyridine class inhibitor of platelet activation
and aggregation mediated by the P2Y12 ADP receptor. Effient is formulated
as the hydrochloride salt, a racemate, which is chemically designated as 5-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl
acetate hydrochloride. Prasugrel hydrochloride has the empirical formula C20H20FNO3S•HCl
representing a molecular weight of 409.90. The chemical structure of prasugrel
hydrochloride is:








Prasugrel hydrochloride is a white to practically white solid. It is soluble at pH 2, slightly soluble at pH 3 to 4, and practically insoluble at pH 6 to 7.5. It also dissolves freely in methanol and is slightly soluble in 1- and 2-propanol and acetone. It is practically insoluble in diethyl ether and ethyl acetate.
Effient is available for oral administration as 5 mg or 10 mg elongated hexagonal,
film-coated, non-scored tablets, debossed on each side. Each yellow 5 mg tablet
is manufactured with 5.49 mg prasugrel hydrochloride, equivalent to 5 mg prasugrel
and each beige 10 mg tablet with 10.98 mg prasugrel hydrochloride, equivalent
to 10 mg of prasugrel. During manufacture and storage, partial conversion from
prasugrel hydrochloride to prasugrel free base may occur. Other ingredients
include mannitol, hypromellose, croscarmellose sodium, microcrystalline cellulose,
and vegetable magnesium stearate. The color coatings contain lactose, hypromellose,
titanium dioxide, triacetin, iron oxide yellow, and iron oxide red (only in
Effient 10 mg tablet).
Last reviewed on RxList: 7/21/2009




Effient Drug Description
EFFIENT
(prasugrel) Tablets

WARNING: BLEEDING RISK
Effient can cause significant, sometimes fatal, bleeding [see WARNINGS
AND PRECAUTIONS and ADVERSE
REACTIONS].
Do not use Effient in patients with active pathological bleeding or a history
of transient ischemic attack or stroke [see CONTRAINDICATIONS].
In patients ≥ 75 years of age, Effient is generally not recommended,
because of the increased risk of fatal and intracranial bleeding and uncertain
benefit, except in high-risk situations (patients with diabetes or a history
of prior MI) where its effect appears to be greater and its use may be considered
[see Use in Specific Populations].
Do not start Effient in patients likely to undergo urgent coronary artery
bypass graft surgery (CABG). When possible, discontinue Effient at least 7 days
prior to any surgery. Additional risk factors for bleeding include:

body weight < 60 kg
propensity to bleed
concomitant use of medications that increase the risk of bleeding (e.g.,
warfarin, heparin, fibrinolytic therapy, chronic use of non-steroidal anti-inflammatory
drugs [NSAIDS])

Suspect bleeding in any patient who is hypotensive and has recently undergone
coronary angiography, percutaneous coronary intervention (PCI), CABG, or other
surgical procedures in the setting of Effient.
If possible, manage bleeding without discontinuing Effient. Discontinuing
Effient, particularly in the first few weeks after acute coronary syndrome,
increases the risk of subsequent cardiovascular events [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of prasugrel (Effient)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;
pale skin, fever, easy bruising, purple or red spots under your skin;
jaundice (yellowing of the skin or eyes);
unexpected vaginal...
Read All Potential Side Effects for Effient »




Effient contains prasugrel, a thienopyridine class inhibitor of platelet activation
and aggregation mediated by the P2Y12 ADP receptor. Effient is formulated
as the hydrochloride salt, a racemate, which is chemically designated as 5-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl
acetate hydrochloride. Prasugrel hydrochloride has the empirical formula C20H20FNO3S•HCl
representing a molecular weight of 409.90. The chemical structure of prasugrel
hydrochloride is:








Prasugrel hydrochloride is a white to practically white solid. It is soluble at pH 2, slightly soluble at pH 3 to 4, and practically insoluble at pH 6 to 7.5. It also dissolves freely in methanol and is slightly soluble in 1- and 2-propanol and acetone. It is practically insoluble in diethyl ether and ethyl acetate.
Effient is available for oral administration as 5 mg or 10 mg elongated hexagonal,
film-coated, non-scored tablets, debossed on each side. Each yellow 5 mg tablet
is manufactured with 5.49 mg prasugrel hydrochloride, equivalent to 5 mg prasugrel
and each beige 10 mg tablet with 10.98 mg prasugrel hydrochloride, equivalent
to 10 mg of prasugrel. During manufacture and storage, partial conversion from
prasugrel hydrochloride to prasugrel free base may occur. Other ingredients
include mannitol, hypromellose, croscarmellose sodium, microcrystalline cellulose,
and vegetable magnesium stearate. The color coatings contain lactose, hypromellose,
titanium dioxide, triacetin, iron oxide yellow, and iron oxide red (only in
Effient 10 mg tablet).
Last reviewed on RxList: 7/21/2009




Effient Drug Description
EFFIENT
(prasugrel) Tablets

WARNING: BLEEDING RISK
Effient can cause significant, sometimes fatal, bleeding [see WARNINGS
AND PRECAUTIONS and ADVERSE
REACTIONS].
Do not use Effient in patients with active pathological bleeding or a history
of transient ischemic attack or stroke [see CONTRAINDICATIONS].
In patients ≥ 75 years of age, Effient is generally not recommended,
because of the increased risk of fatal and intracranial bleeding and uncertain
benefit, except in high-risk situations (patients with diabetes or a history
of prior MI) where its effect appears to be greater and its use may be considered
[see Use in Specific Populations].
Do not start Effient in patients likely to undergo urgent coronary artery
bypass graft surgery (CABG). When possible, discontinue Effient at least 7 days
prior to any surgery. Additional risk factors for bleeding include:

body weight < 60 kg
propensity to bleed
concomitant use of medications that increase the risk of bleeding (e.g.,
warfarin, heparin, fibrinolytic therapy, chronic use of non-steroidal anti-inflammatory
drugs [NSAIDS])

Suspect bleeding in any patient who is hypotensive and has recently undergone
coronary angiography, percutaneous coronary intervention (PCI), CABG, or other
surgical procedures in the setting of Effient.
If possible, manage bleeding without discontinuing Effient. Discontinuing
Effient, particularly in the first few weeks after acute coronary syndrome,
increases the risk of subsequent cardiovascular events [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of prasugrel (Effient)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;
pale skin, fever, easy bruising, purple or red spots under your skin;
jaundice (yellowing of the skin or eyes);
unexpected vaginal...
Read All Potential Side Effects for Effient »




Effient contains prasugrel, a thienopyridine class inhibitor of platelet activation
and aggregation mediated by the P2Y12 ADP receptor. Effient is formulated
as the hydrochloride salt, a racemate, which is chemically designated as 5-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl
acetate hydrochloride. Prasugrel hydrochloride has the empirical formula C20H20FNO3S•HCl
representing a molecular weight of 409.90. The chemical structure of prasugrel
hydrochloride is:








Prasugrel hydrochloride is a white to practically white solid. It is soluble at pH 2, slightly soluble at pH 3 to 4, and practically insoluble at pH 6 to 7.5. It also dissolves freely in methanol and is slightly soluble in 1- and 2-propanol and acetone. It is practically insoluble in diethyl ether and ethyl acetate.
Effient is available for oral administration as 5 mg or 10 mg elongated hexagonal,
film-coated, non-scored tablets, debossed on each side. Each yellow 5 mg tablet
is manufactured with 5.49 mg prasugrel hydrochloride, equivalent to 5 mg prasugrel
and each beige 10 mg tablet with 10.98 mg prasugrel hydrochloride, equivalent
to 10 mg of prasugrel. During manufacture and storage, partial conversion from
prasugrel hydrochloride to prasugrel free base may occur. Other ingredients
include mannitol, hypromellose, croscarmellose sodium, microcrystalline cellulose,
and vegetable magnesium stearate. The color coatings contain lactose, hypromellose,
titanium dioxide, triacetin, iron oxide yellow, and iron oxide red (only in
Effient 10 mg tablet).
Last reviewed on RxList: 7/21/2009




Effient Drug Description
EFFIENT
(prasugrel) Tablets

WARNING: BLEEDING RISK
Effient can cause significant, sometimes fatal, bleeding [see WARNINGS
AND PRECAUTIONS and ADVERSE
REACTIONS].
Do not use Effient in patients with active pathological bleeding or a history
of transient ischemic attack or stroke [see CONTRAINDICATIONS].
In patients ≥ 75 years of age, Effient is generally not recommended,
because of the increased risk of fatal and intracranial bleeding and uncertain
benefit, except in high-risk situations (patients with diabetes or a history
of prior MI) where its effect appears to be greater and its use may be considered
[see Use in Specific Populations].
Do not start Effient in patients likely to undergo urgent coronary artery
bypass graft surgery (CABG). When possible, discontinue Effient at least 7 days
prior to any surgery. Additional risk factors for bleeding include:

body weight < 60 kg
propensity to bleed
concomitant use of medications that increase the risk of bleeding (e.g.,
warfarin, heparin, fibrinolytic therapy, chronic use of non-steroidal anti-inflammatory
drugs [NSAIDS])

Suspect bleeding in any patient who is hypotensive and has recently undergone
coronary angiography, percutaneous coronary intervention (PCI), CABG, or other
surgical procedures in the setting of Effient.
If possible, manage bleeding without discontinuing Effient. Discontinuing
Effient, particularly in the first few weeks after acute coronary syndrome,
increases the risk of subsequent cardiovascular events [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of prasugrel (Effient)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;
pale skin, fever, easy bruising, purple or red spots under your skin;
jaundice (yellowing of the skin or eyes);
unexpected vaginal...
Read All Potential Side Effects for Effient »




Effient contains prasugrel, a thienopyridine class inhibitor of platelet activation
and aggregation mediated by the P2Y12 ADP receptor. Effient is formulated
as the hydrochloride salt, a racemate, which is chemically designated as 5-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl
acetate hydrochloride. Prasugrel hydrochloride has the empirical formula C20H20FNO3S•HCl
representing a molecular weight of 409.90. The chemical structure of prasugrel
hydrochloride is:








Prasugrel hydrochloride is a white to practically white solid. It is soluble at pH 2, slightly soluble at pH 3 to 4, and practically insoluble at pH 6 to 7.5. It also dissolves freely in methanol and is slightly soluble in 1- and 2-propanol and acetone. It is practically insoluble in diethyl ether and ethyl acetate.
Effient is available for oral administration as 5 mg or 10 mg elongated hexagonal,
film-coated, non-scored tablets, debossed on each side. Each yellow 5 mg tablet
is manufactured with 5.49 mg prasugrel hydrochloride, equivalent to 5 mg prasugrel
and each beige 10 mg tablet with 10.98 mg prasugrel hydrochloride, equivalent
to 10 mg of prasugrel. During manufacture and storage, partial conversion from
prasugrel hydrochloride to prasugrel free base may occur. Other ingredients
include mannitol, hypromellose, croscarmellose sodium, microcrystalline cellulose,
and vegetable magnesium stearate. The color coatings contain lactose, hypromellose,
titanium dioxide, triacetin, iron oxide yellow, and iron oxide red (only in
Effient 10 mg tablet).
Last reviewed on RxList: 7/21/2009




Effient Drug Description
EFFIENT
(prasugrel) Tablets

WARNING: BLEEDING RISK
Effient can cause significant, sometimes fatal, bleeding [see WARNINGS
AND PRECAUTIONS and ADVERSE
REACTIONS].
Do not use Effient in patients with active pathological bleeding or a history
of transient ischemic attack or stroke [see CONTRAINDICATIONS].
In patients ≥ 75 years of age, Effient is generally not recommended,
because of the increased risk of fatal and intracranial bleeding and uncertain
benefit, except in high-risk situations (patients with diabetes or a history
of prior MI) where its effect appears to be greater and its use may be considered
[see Use in Specific Populations].
Do not start Effient in patients likely to undergo urgent coronary artery
bypass graft surgery (CABG). When possible, discontinue Effient at least 7 days
prior to any surgery. Additional risk factors for bleeding include:

body weight < 60 kg
propensity to bleed
concomitant use of medications that increase the risk of bleeding (e.g.,
warfarin, heparin, fibrinolytic therapy, chronic use of non-steroidal anti-inflammatory
drugs [NSAIDS])

Suspect bleeding in any patient who is hypotensive and has recently undergone
coronary angiography, percutaneous coronary intervention (PCI), CABG, or other
surgical procedures in the setting of Effient.
If possible, manage bleeding without discontinuing Effient. Discontinuing
Effient, particularly in the first few weeks after acute coronary syndrome,
increases the risk of subsequent cardiovascular events [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of prasugrel (Effient)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

unusual bleeding such as nosebleeds, bleeding gums, or any bleeding that will not stop;
pale skin, fever, easy bruising, purple or red spots under your skin;
jaundice (yellowing of the skin or eyes);
unexpected vaginal...
Read All Potential Side Effects for Effient »




Effient contains prasugrel, a thienopyridine class inhibitor of platelet activation
and aggregation mediated by the P2Y12 ADP receptor. Effient is formulated
as the hydrochloride salt, a racemate, which is chemically designated as 5-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl
acetate hydrochloride. Prasugrel hydrochloride has the empirical formula C20H20FNO3S•HCl
representing a molecular weight of 409.90. The chemical structure of prasugrel
hydrochloride is:








Prasugrel hydrochloride is a white to practically white solid. It is soluble at pH 2, slightly soluble at pH 3 to 4, and practically insoluble at pH 6 to 7.5. It also dissolves freely in methanol and is slightly soluble in 1- and 2-propanol and acetone. It is practically insoluble in diethyl ether and ethyl acetate.
Effient is available for oral administration as 5 mg or 10 mg elongated hexagonal,
film-coated, non-scored tablets, debossed on each side. Each yellow 5 mg tablet
is manufactured with 5.49 mg prasugrel hydrochloride, equivalent to 5 mg prasugrel
and each beige 10 mg tablet with 10.98 mg prasugrel hydrochloride, equivalent
to 10 mg of prasugrel. During manufacture and storage, partial conversion from
prasugrel hydrochloride to prasugrel free base may occur. Other ingredients
include mannitol, hypromellose, croscarmellose sodium, microcrystalline cellulose,
and vegetable magnesium stearate. The color coatings contain lactose, hypromellose,
titanium dioxide, triacetin, iron oxide yellow, and iron oxide red (only in
Effient 10 mg tablet).
Last reviewed on RxList: 7/21/2009





Other reviews about Prasugrel Tablets on wordpress

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The FDA has approved prasugrel (Effient) to reduce the risk of MI in ACS patients undergoing PCI. Lilly had hoped to claim a broader indication for the drug. The […]


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Other reviews about Prasugrel Tablets on web:

Learn about the prescription medication Effient (Prasugrel Tablets), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Effient (Prasugrel Tablets) Drug Information: Uses, Side Effects ...


Before taking prasugrel, tell your doctor and pharmacist if you are allergic to prasugrel, any other medications, or any of the ingredients in prasugrel tablets. Prasugrel: MedlinePlus Drug Information


The U.S. Food and Drug Administration has approved the blood-thinning drug Effient tablets (prasugrel) to reduce the risk of blood clots from forming in patients who undergo ... FDA Approves Effient to Reduce the Risk of Heart Attack in ...


Effient ® (prasugrel) is indicated to help reduce the risk of a future heart-related event, such as a heart attack or stent clot, in patients who had an acute coronary syndrome (ACS ... Oral Antiplatelet, Heart Stent, Percutaneous Coronary Intervention ...


Microsoft Word - prasugrel 5 and 10 mg tablets _Efient_ FINAL August 2009 Revised September 2009.doc for website.doc Scottish Medicines Consortium


Page 1 Risk Evaluation and Mitigation Strategy NDA 22-307 Proposed Trade Name: EFFIENT (prasugrel) United States Food and Drug Administration Division of Cardiovascular and ... Effient (prasugrel) Tablets, Eli Lilly and Company


Efient (prasugrel) 10mg is used in patients with heart disease (recent heart attack, unstable angina) who undergo a certain heart procedure (angioplasty). Efient (prasugrel) 10mg ... Buy Efient (prasugrel) 10mg Tablet Online


Effient (Prasugrel) tablets are available in the two strengths: Effient 5 mg, Effient 10 mg. Order cheap Effient online or contact Blue Sky Pharmacy: Generic Effient (Prasugrel) | Buy Effient Generic Pharmacy 1.866 ...


Prasugrel can cause severe and sometimes fatal bleeding. It should not be used in ... Hello, I need to find Effient (Prasugrel Tablets) for my dad, do you know where and how? Prasugrel Facts and Comparisons at Drugs.com


Prasugrel Español: Prasugrel, Tableta oral Prasugrel Oral tablet What is this medicine? PRASUGREL (PRA soo grel) helps to prevent blood clots Prasugrel: Information from Answers.com





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