Reviews Prandimet


No reviews yet.

Prandimet Drug Description
PrandiMet®
(repaglinide and metformin HCl) Tablets.

WARNING: LACTIC ACIDOSIS
Lactic acidosis is a rare but serious complication that can occur due to
metformin accumulation. The risk increases with conditions such as sepsis, dehydration,
excess alcohol intake, hepatic impairment, renal impairment, and acute congestive
heart failure.
The onset of lactic acidosis often is subtle, and accompanied only by nonspecific
symptoms such as malaise, myalgias, respiratory distress, increasing somnolence,
and nonspecific abdominal distress.
Laboratory abnormalities include low pH, increased anion gap and elevated
blood lactate.
If acidosis is suspected, PrandiMet should be discontinued and the patient
hospitalized immediately [See WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of metformin and repaglinide (PrandiMet)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

chest pain;
sudden numbness or weakness, especially on one side of the body; or
stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side...
Read All Potential Side Effects for Prandimet »




PrandiMet (repaglinide and metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: repaglinide and metformin HCl. The concomitant use of repaglinide and metformin HCl has been previously approved based on clinical trials in patients with type 2 diabetes inadequately controlled on exercise, diet, and metformin HCl alone.
Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl)
amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea
insulin secretagogues. Repaglinide is a white to off-white powder with molecular
formula C27H36N2O4 and a molecular
weight of 452.6 with the structural formula as shown below. Repaglinide is freely
soluble in methanol and ethanol. The pKa of repaglinide in acid is 3.9, and
the pKa in amine is 6.0.
Structural formula of Repaglinide







Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not
chemically or pharmacologically related to any other classes of oral antihyperglycemic
agents. Metformin HCl is a white to off-white crystalline compound with a molecular
formula of C4H11N5•HCl and a molecular weight
of 165.63. Metformin HCl is freely soluble in water and is practically insoluble
in acetone, ether, and chloroform. The pKa of metformin HCl is 12.4. The pH
of a 1% aqueous solution of metformin HCl is 6.68. The structural formula of
metformin HCl is:
Structural formula of Metformin HCl







PrandiMet is available as a tablet for oral administration containing 1 mg repaglinide with 500 mg metformin HCl (1 mg/500 mg) or 2 mg repaglinide with 500 mg metformin HCl (2 mg/500 mg) formulated with the following inactive ingredients: poloxamer 188, microcrystalline cellulose, polacrillin potassium, magnesium stearate, hypromellose 3cp or 6cp, povidone, meglumine, sorbitol, talc, titanium dioxide, red or yellow iron oxide, and polyethylene glycol. Propylene glycol is present in the 2 mg/500 mg PrandiMet tablets.
Last reviewed on RxList: 6/25/2010




Prandimet Drug Description
PrandiMet®
(repaglinide and metformin HCl) Tablets.

WARNING: LACTIC ACIDOSIS
Lactic acidosis is a rare but serious complication that can occur due to
metformin accumulation. The risk increases with conditions such as sepsis, dehydration,
excess alcohol intake, hepatic impairment, renal impairment, and acute congestive
heart failure.
The onset of lactic acidosis often is subtle, and accompanied only by nonspecific
symptoms such as malaise, myalgias, respiratory distress, increasing somnolence,
and nonspecific abdominal distress.
Laboratory abnormalities include low pH, increased anion gap and elevated
blood lactate.
If acidosis is suspected, PrandiMet should be discontinued and the patient
hospitalized immediately [See WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of metformin and repaglinide (PrandiMet)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

chest pain;
sudden numbness or weakness, especially on one side of the body; or
stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side...
Read All Potential Side Effects for Prandimet »




PrandiMet (repaglinide and metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: repaglinide and metformin HCl. The concomitant use of repaglinide and metformin HCl has been previously approved based on clinical trials in patients with type 2 diabetes inadequately controlled on exercise, diet, and metformin HCl alone.
Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl)
amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea
insulin secretagogues. Repaglinide is a white to off-white powder with molecular
formula C27H36N2O4 and a molecular
weight of 452.6 with the structural formula as shown below. Repaglinide is freely
soluble in methanol and ethanol. The pKa of repaglinide in acid is 3.9, and
the pKa in amine is 6.0.
Structural formula of Repaglinide







Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not
chemically or pharmacologically related to any other classes of oral antihyperglycemic
agents. Metformin HCl is a white to off-white crystalline compound with a molecular
formula of C4H11N5•HCl and a molecular weight
of 165.63. Metformin HCl is freely soluble in water and is practically insoluble
in acetone, ether, and chloroform. The pKa of metformin HCl is 12.4. The pH
of a 1% aqueous solution of metformin HCl is 6.68. The structural formula of
metformin HCl is:
Structural formula of Metformin HCl







PrandiMet is available as a tablet for oral administration containing 1 mg repaglinide with 500 mg metformin HCl (1 mg/500 mg) or 2 mg repaglinide with 500 mg metformin HCl (2 mg/500 mg) formulated with the following inactive ingredients: poloxamer 188, microcrystalline cellulose, polacrillin potassium, magnesium stearate, hypromellose 3cp or 6cp, povidone, meglumine, sorbitol, talc, titanium dioxide, red or yellow iron oxide, and polyethylene glycol. Propylene glycol is present in the 2 mg/500 mg PrandiMet tablets.
Last reviewed on RxList: 6/25/2010




Prandimet Drug Description
PrandiMet®
(repaglinide and metformin HCl) Tablets.

WARNING: LACTIC ACIDOSIS
Lactic acidosis is a rare but serious complication that can occur due to
metformin accumulation. The risk increases with conditions such as sepsis, dehydration,
excess alcohol intake, hepatic impairment, renal impairment, and acute congestive
heart failure.
The onset of lactic acidosis often is subtle, and accompanied only by nonspecific
symptoms such as malaise, myalgias, respiratory distress, increasing somnolence,
and nonspecific abdominal distress.
Laboratory abnormalities include low pH, increased anion gap and elevated
blood lactate.
If acidosis is suspected, PrandiMet should be discontinued and the patient
hospitalized immediately [See WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of metformin and repaglinide (PrandiMet)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

chest pain;
sudden numbness or weakness, especially on one side of the body; or
stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side...
Read All Potential Side Effects for Prandimet »




PrandiMet (repaglinide and metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: repaglinide and metformin HCl. The concomitant use of repaglinide and metformin HCl has been previously approved based on clinical trials in patients with type 2 diabetes inadequately controlled on exercise, diet, and metformin HCl alone.
Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl)
amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea
insulin secretagogues. Repaglinide is a white to off-white powder with molecular
formula C27H36N2O4 and a molecular
weight of 452.6 with the structural formula as shown below. Repaglinide is freely
soluble in methanol and ethanol. The pKa of repaglinide in acid is 3.9, and
the pKa in amine is 6.0.
Structural formula of Repaglinide







Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not
chemically or pharmacologically related to any other classes of oral antihyperglycemic
agents. Metformin HCl is a white to off-white crystalline compound with a molecular
formula of C4H11N5•HCl and a molecular weight
of 165.63. Metformin HCl is freely soluble in water and is practically insoluble
in acetone, ether, and chloroform. The pKa of metformin HCl is 12.4. The pH
of a 1% aqueous solution of metformin HCl is 6.68. The structural formula of
metformin HCl is:
Structural formula of Metformin HCl







PrandiMet is available as a tablet for oral administration containing 1 mg repaglinide with 500 mg metformin HCl (1 mg/500 mg) or 2 mg repaglinide with 500 mg metformin HCl (2 mg/500 mg) formulated with the following inactive ingredients: poloxamer 188, microcrystalline cellulose, polacrillin potassium, magnesium stearate, hypromellose 3cp or 6cp, povidone, meglumine, sorbitol, talc, titanium dioxide, red or yellow iron oxide, and polyethylene glycol. Propylene glycol is present in the 2 mg/500 mg PrandiMet tablets.
Last reviewed on RxList: 6/25/2010




Prandimet Drug Description
PrandiMet®
(repaglinide and metformin HCl) Tablets.

WARNING: LACTIC ACIDOSIS
Lactic acidosis is a rare but serious complication that can occur due to
metformin accumulation. The risk increases with conditions such as sepsis, dehydration,
excess alcohol intake, hepatic impairment, renal impairment, and acute congestive
heart failure.
The onset of lactic acidosis often is subtle, and accompanied only by nonspecific
symptoms such as malaise, myalgias, respiratory distress, increasing somnolence,
and nonspecific abdominal distress.
Laboratory abnormalities include low pH, increased anion gap and elevated
blood lactate.
If acidosis is suspected, PrandiMet should be discontinued and the patient
hospitalized immediately [See WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of metformin and repaglinide (PrandiMet)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

chest pain;
sudden numbness or weakness, especially on one side of the body; or
stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side...
Read All Potential Side Effects for Prandimet »




PrandiMet (repaglinide and metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: repaglinide and metformin HCl. The concomitant use of repaglinide and metformin HCl has been previously approved based on clinical trials in patients with type 2 diabetes inadequately controlled on exercise, diet, and metformin HCl alone.
Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl)
amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea
insulin secretagogues. Repaglinide is a white to off-white powder with molecular
formula C27H36N2O4 and a molecular
weight of 452.6 with the structural formula as shown below. Repaglinide is freely
soluble in methanol and ethanol. The pKa of repaglinide in acid is 3.9, and
the pKa in amine is 6.0.
Structural formula of Repaglinide







Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not
chemically or pharmacologically related to any other classes of oral antihyperglycemic
agents. Metformin HCl is a white to off-white crystalline compound with a molecular
formula of C4H11N5•HCl and a molecular weight
of 165.63. Metformin HCl is freely soluble in water and is practically insoluble
in acetone, ether, and chloroform. The pKa of metformin HCl is 12.4. The pH
of a 1% aqueous solution of metformin HCl is 6.68. The structural formula of
metformin HCl is:
Structural formula of Metformin HCl







PrandiMet is available as a tablet for oral administration containing 1 mg repaglinide with 500 mg metformin HCl (1 mg/500 mg) or 2 mg repaglinide with 500 mg metformin HCl (2 mg/500 mg) formulated with the following inactive ingredients: poloxamer 188, microcrystalline cellulose, polacrillin potassium, magnesium stearate, hypromellose 3cp or 6cp, povidone, meglumine, sorbitol, talc, titanium dioxide, red or yellow iron oxide, and polyethylene glycol. Propylene glycol is present in the 2 mg/500 mg PrandiMet tablets.
Last reviewed on RxList: 6/25/2010




Prandimet Drug Description
PrandiMet®
(repaglinide and metformin HCl) Tablets.

WARNING: LACTIC ACIDOSIS
Lactic acidosis is a rare but serious complication that can occur due to
metformin accumulation. The risk increases with conditions such as sepsis, dehydration,
excess alcohol intake, hepatic impairment, renal impairment, and acute congestive
heart failure.
The onset of lactic acidosis often is subtle, and accompanied only by nonspecific
symptoms such as malaise, myalgias, respiratory distress, increasing somnolence,
and nonspecific abdominal distress.
Laboratory abnormalities include low pH, increased anion gap and elevated
blood lactate.
If acidosis is suspected, PrandiMet should be discontinued and the patient
hospitalized immediately [See WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of metformin and repaglinide (PrandiMet)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

chest pain;
sudden numbness or weakness, especially on one side of the body; or
stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side...
Read All Potential Side Effects for Prandimet »




PrandiMet (repaglinide and metformin HCl) tablets contain two oral antihyperglycemic drugs used in the management of type 2 diabetes: repaglinide and metformin HCl. The concomitant use of repaglinide and metformin HCl has been previously approved based on clinical trials in patients with type 2 diabetes inadequately controlled on exercise, diet, and metformin HCl alone.
Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl)
amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea
insulin secretagogues. Repaglinide is a white to off-white powder with molecular
formula C27H36N2O4 and a molecular
weight of 452.6 with the structural formula as shown below. Repaglinide is freely
soluble in methanol and ethanol. The pKa of repaglinide in acid is 3.9, and
the pKa in amine is 6.0.
Structural formula of Repaglinide







Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not
chemically or pharmacologically related to any other classes of oral antihyperglycemic
agents. Metformin HCl is a white to off-white crystalline compound with a molecular
formula of C4H11N5•HCl and a molecular weight
of 165.63. Metformin HCl is freely soluble in water and is practically insoluble
in acetone, ether, and chloroform. The pKa of metformin HCl is 12.4. The pH
of a 1% aqueous solution of metformin HCl is 6.68. The structural formula of
metformin HCl is:
Structural formula of Metformin HCl







PrandiMet is available as a tablet for oral administration containing 1 mg repaglinide with 500 mg metformin HCl (1 mg/500 mg) or 2 mg repaglinide with 500 mg metformin HCl (2 mg/500 mg) formulated with the following inactive ingredients: poloxamer 188, microcrystalline cellulose, polacrillin potassium, magnesium stearate, hypromellose 3cp or 6cp, povidone, meglumine, sorbitol, talc, titanium dioxide, red or yellow iron oxide, and polyethylene glycol. Propylene glycol is present in the 2 mg/500 mg PrandiMet tablets.
Last reviewed on RxList: 6/25/2010





Other reviews about Prandimet on wordpress

PrandiMet Coming Soon
  by stldiabetes
On June 23, the FDA approved a fixed-dose combination of the meglitinide, repaglinide, with the biguanide, metformin HCl (PrandiMet; Novo Nordisk, Inc, and marketed by Sciele Pharma) for […]


FDA MedWatch - May 2010 Drug Safety Labeling Changes
  by irbtipoftheweek
The MedWatch May 2010 Drug Safety Labeling Changes posting includes 23 products with safety labeling changes to the following sections: BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, PATIENT […]



Other reviews about Prandimet on web:

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use PrandiMet safely and effectively. See full prescribing information for ... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not ...


PrandiMet (repaglinide and metformin) is used to treat type 2 diabetes (non-insulin dependent diabetes). Includes PrandiMet side effects, interactions and indications. PrandiMet Information from Drugs.com


Accurate, FDA approved PrandiMet information for healthcare professionals and patients - brought to you by Drugs.com. PrandiMet Official FDA information, side effects and uses.


Learn about the prescription medication Prandimet (Repaglinide and Metformin HCl Tablets), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Prandimet (Repaglinide and Metformin HCl Tablets) Drug Information ...


PrandiMet is a prescription medication used to treat type 2 diabetes. This selection from the eMedTV Web library features an overview of PrandiMet, including information on how it ... PrandiMet


What is PrandiMet? Metformin and repaglinide are oral diabetes medications that help control blood sugar levels. Repaglinide works by causing the pancreas to produce insulin. PrandiMet - Drugs & Treatments - Revolution Health


Find patient medical information for Prandimet Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Prandimet Oral : Uses, Side Effects, Interactions, Pictures ...


Learn about Prandimet (Repaglinide and Metformin HCl Tablets) - Side Effects, Drug Interactions, Pictures, Patient Information on RxList Prandimet (Repaglinide and Metformin HCl Tablets) Patient Drug ...


Learn about PrandiMet from the publishers of the Physicians Desk Reference. Find prescription drug information resources including interactions, side effects, symptoms ... PrandiMet | Prescription Drug Information, Side Effects | PDRHealth


Prandimet Information, Learn About Prandimet, Prandimet Forums, How to Take Prandimet, Prandimet Side Effects, Prandimet Interactions, Discussion Threads, Medication Warnings ... Prandimet - The People's Medicine Community





Featured Reviews

Reviews Propoxyphene Napsylate and Acetaminophen

Darvocet-N Drug Description DARVOCET-N® 50 and DARVOCET-N® 100 (propoxyphene napsylate and acetaminophen) Tablets, USP WARNINGS There have been numerous cases of accidental and intentional overdose with propoxyphene...
Read More  |  Review This
Reviews Methocarbamol and Aspirin

Robaxisal Drug Description DRUG DESCRIPTION What are the possible side effects of aspirin and methocarbamol (Robaxisal)? If you experience any of the following serious side effects, stop taking aspirin and methocarbamol and seek...
Read More  |  Review This
Reviews Diazepam Rectal Gel

Diastat Drug Description Diastat® (diazepam) Rectal Gel DiastatAcuDial® (diazepam) Rectal Gel Rectal Delivery System DRUG DESCRIPTION What are the possible side effects of diazepam rectal (Diastat AcuDial, Diastat Pediatric)? Get...
Read More  |  Review This
Reviews Oxytetracycline and Hydrocortisone

Terra-Cortril Drug Description TERRA-CORTRIL ®         10 mg/mL Oxytetracycline         5 mg/mL Hydrocortisone Acetate        ...
Read More  |  Review This
Reviews Mumpsvax

Mumpsvax Drug Description MUMPSVAX® (Mumps Virus Vaccine Live) Jeryl Lynn™ Strain DRUG DESCRIPTION What are the possible side effects of this vaccine (Mumpsvax)? Keep track of any and all side effects your child has after...
Read More  |  Review This
Recent News
59sec - the BEST lead management system around!
We tested 59sec - THE lead management system and we love it. 59sec helps small and medium companies to answer leads in maximum 59 seconds. Why...
MOVEorPAY - our favorite facebook app
We do love MOVEorPAY motivational facebook app, because it is very cool and useful. It makes you finish stuff that you know are good for you, but from various reasons, you never do...
ReviewsAZ is almost ready to be officially launched
yes, we have just a few loose ends to tie and we are ready to go :) meanwhile, I am putting some reviews on the site, so people will not get an empty site at the launch....