Reviews Pegaspargase


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Oncaspar Drug Description
Oncaspar®
(pegaspargase) Intravenous -or- Intramuscular Injection
DRUG DESCRIPTION



What are the possible side effects of pegaspargase (Oncaspar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
...
Read All Potential Side Effects for Oncaspar »




Oncaspar® (pegaspargase) is a modified version of the enzyme L-asparaginase.
To produce Oncaspar®, L-asparaginase is modified by covalently conjugating
units of monomethoxypolyethylene glycol (PEG), molecular weight of 5,000, to
the enzyme, forming the active ingredient PEG-L-asparaginase. The L-asparaginase
(L-asparagine amidohydrolase, type EC-2, EC 3.5.1.1) used in the manufacture
of Oncaspar® is derived from E coli and supplied by Ovation Pharmaceuticals
(U.S. License No. 1688) under a shared manufacturing arrangement. Oncaspar®
activity is expressed in International Units (IU) according to the recommendation
of the International Union of Biochemistry. One IU of L-asparaginase is defined
as that amount of enzyme required to generate 1 umol of ammonia per minute at
pH 7.3 and 37°C.
Oncaspar® is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains Oncaspar® 750 IU ± 20% (based on specific activity of at least 85 IU per milligram protein), 1.20 mg monobasic sodium phosphate, USP, 5.58 mg dibasic sodium phosphate, USP, and 8.50 mg sodium chloride, USP, in water for injection, USP.Last reviewed on RxList: 3/2/2009




Oncaspar Drug Description
Oncaspar®
(pegaspargase) Intravenous -or- Intramuscular Injection
DRUG DESCRIPTION



What are the possible side effects of pegaspargase (Oncaspar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
...
Read All Potential Side Effects for Oncaspar »




Oncaspar® (pegaspargase) is a modified version of the enzyme L-asparaginase.
To produce Oncaspar®, L-asparaginase is modified by covalently conjugating
units of monomethoxypolyethylene glycol (PEG), molecular weight of 5,000, to
the enzyme, forming the active ingredient PEG-L-asparaginase. The L-asparaginase
(L-asparagine amidohydrolase, type EC-2, EC 3.5.1.1) used in the manufacture
of Oncaspar® is derived from E coli and supplied by Ovation Pharmaceuticals
(U.S. License No. 1688) under a shared manufacturing arrangement. Oncaspar®
activity is expressed in International Units (IU) according to the recommendation
of the International Union of Biochemistry. One IU of L-asparaginase is defined
as that amount of enzyme required to generate 1 umol of ammonia per minute at
pH 7.3 and 37°C.
Oncaspar® is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains Oncaspar® 750 IU ± 20% (based on specific activity of at least 85 IU per milligram protein), 1.20 mg monobasic sodium phosphate, USP, 5.58 mg dibasic sodium phosphate, USP, and 8.50 mg sodium chloride, USP, in water for injection, USP.Last reviewed on RxList: 3/2/2009




Oncaspar Drug Description
Oncaspar®
(pegaspargase) Intravenous -or- Intramuscular Injection
DRUG DESCRIPTION



What are the possible side effects of pegaspargase (Oncaspar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
...
Read All Potential Side Effects for Oncaspar »




Oncaspar® (pegaspargase) is a modified version of the enzyme L-asparaginase.
To produce Oncaspar®, L-asparaginase is modified by covalently conjugating
units of monomethoxypolyethylene glycol (PEG), molecular weight of 5,000, to
the enzyme, forming the active ingredient PEG-L-asparaginase. The L-asparaginase
(L-asparagine amidohydrolase, type EC-2, EC 3.5.1.1) used in the manufacture
of Oncaspar® is derived from E coli and supplied by Ovation Pharmaceuticals
(U.S. License No. 1688) under a shared manufacturing arrangement. Oncaspar®
activity is expressed in International Units (IU) according to the recommendation
of the International Union of Biochemistry. One IU of L-asparaginase is defined
as that amount of enzyme required to generate 1 umol of ammonia per minute at
pH 7.3 and 37°C.
Oncaspar® is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains Oncaspar® 750 IU ± 20% (based on specific activity of at least 85 IU per milligram protein), 1.20 mg monobasic sodium phosphate, USP, 5.58 mg dibasic sodium phosphate, USP, and 8.50 mg sodium chloride, USP, in water for injection, USP.Last reviewed on RxList: 3/2/2009




Oncaspar Drug Description
Oncaspar®
(pegaspargase) Intravenous -or- Intramuscular Injection
DRUG DESCRIPTION



What are the possible side effects of pegaspargase (Oncaspar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
...
Read All Potential Side Effects for Oncaspar »




Oncaspar® (pegaspargase) is a modified version of the enzyme L-asparaginase.
To produce Oncaspar®, L-asparaginase is modified by covalently conjugating
units of monomethoxypolyethylene glycol (PEG), molecular weight of 5,000, to
the enzyme, forming the active ingredient PEG-L-asparaginase. The L-asparaginase
(L-asparagine amidohydrolase, type EC-2, EC 3.5.1.1) used in the manufacture
of Oncaspar® is derived from E coli and supplied by Ovation Pharmaceuticals
(U.S. License No. 1688) under a shared manufacturing arrangement. Oncaspar®
activity is expressed in International Units (IU) according to the recommendation
of the International Union of Biochemistry. One IU of L-asparaginase is defined
as that amount of enzyme required to generate 1 umol of ammonia per minute at
pH 7.3 and 37°C.
Oncaspar® is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains Oncaspar® 750 IU ± 20% (based on specific activity of at least 85 IU per milligram protein), 1.20 mg monobasic sodium phosphate, USP, 5.58 mg dibasic sodium phosphate, USP, and 8.50 mg sodium chloride, USP, in water for injection, USP.Last reviewed on RxList: 3/2/2009




Oncaspar Drug Description
Oncaspar®
(pegaspargase) Intravenous -or- Intramuscular Injection
DRUG DESCRIPTION



What are the possible side effects of pegaspargase (Oncaspar)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
...
Read All Potential Side Effects for Oncaspar »




Oncaspar® (pegaspargase) is a modified version of the enzyme L-asparaginase.
To produce Oncaspar®, L-asparaginase is modified by covalently conjugating
units of monomethoxypolyethylene glycol (PEG), molecular weight of 5,000, to
the enzyme, forming the active ingredient PEG-L-asparaginase. The L-asparaginase
(L-asparagine amidohydrolase, type EC-2, EC 3.5.1.1) used in the manufacture
of Oncaspar® is derived from E coli and supplied by Ovation Pharmaceuticals
(U.S. License No. 1688) under a shared manufacturing arrangement. Oncaspar®
activity is expressed in International Units (IU) according to the recommendation
of the International Union of Biochemistry. One IU of L-asparaginase is defined
as that amount of enzyme required to generate 1 umol of ammonia per minute at
pH 7.3 and 37°C.
Oncaspar® is supplied as a clear, colorless, preservative-free, isotonic sterile solution in phosphate-buffered saline, pH 7.3. Each milliliter contains Oncaspar® 750 IU ± 20% (based on specific activity of at least 85 IU per milligram protein), 1.20 mg monobasic sodium phosphate, USP, 5.58 mg dibasic sodium phosphate, USP, and 8.50 mg sodium chloride, USP, in water for injection, USP.Last reviewed on RxList: 3/2/2009





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Other reviews about Pegaspargase on web:

About Wikipedia; Community portal; Recent changes; Contact Wikipedia; Donate to Wikipedia; Help Pegaspargase - Wikipedia, the free encyclopedia


Pegaspargase Key Terms: Acute lymphocytic leukemia , Induction therapy . Definition Pegaspargase (also known as PEG-L-asparaginase and Oncaspar) is a Pegaspargase: Information from Answers.com


Pegaspargase Brand names: Oncaspar® Español: Pegaspargasa (E. coli) Solución para inyección Pegaspargase (E Pegaspargase: Information from Answers.com


Learn about the prescription medication Oncaspar (Pegaspargase), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Oncaspar (Pegaspargase) Drug Information: Uses, Side Effects, Drug ...


All about Pegaspargase. View complete and up to date Pegaspargase information - part of the Drugs.com trusted medication database. Pegaspargase Facts and Comparisons at Drugs.com


Pegaspargase is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. This medication is classified as an enzyme. Oncaspar, PEG-L-asparaginase Pegaspargase, Oncaspar, PEG-L-asparaginase - Chemotherapy Drugs ...


This page contains brief information about pegaspargase and a collection of links to more information about the use of this drug and ongoing clinical trials. Pegaspargase - National Cancer Institute


Physician reviewed pegaspargase patient information - includes pegaspargase description, dosage and directions. pegaspargase medical facts from Drugs.com


Features information about dosage, usage, warnings, and side effects. Pegaspargase: MedlinePlus Drug Information


The search textbox has an autosuggest feature. When you enter three or more characters, a list of up to 10 suggestions will popup under the ... Definition of pegaspargase - National Cancer Institute Drug ...





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