Reviews Pantoprazole Sodium


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Protonix I.V. Drug Description
PROTONIX® I.V.
(pantoprazole sodium) for Injection
DRUG DESCRIPTION
The active ingredient in PROTONIX® I.V. (pantoprazole sodium) for Injection
is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]
sulfinyl]- 1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C16H14F2N3NaO4S,
with a molecular weight of 405.4. The structural formula is:







Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. The reconstituted solution of PROTONIX I.V. for Injection is in the pH range 9.0 to 10.5.
PROTONIX I.V. for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing pantoprazole sodium, equivalent to 40 mg of pantoprazole, edetate disodium (1 mg), and sodium hydroxide to adjust pH.
Last reviewed on RxList: 5/5/2008




Protonix I.V. Drug Description
PROTONIX® I.V.
(pantoprazole sodium) for Injection
DRUG DESCRIPTION
The active ingredient in PROTONIX® I.V. (pantoprazole sodium) for Injection
is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]
sulfinyl]- 1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C16H14F2N3NaO4S,
with a molecular weight of 405.4. The structural formula is:







Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. The reconstituted solution of PROTONIX I.V. for Injection is in the pH range 9.0 to 10.5.
PROTONIX I.V. for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing pantoprazole sodium, equivalent to 40 mg of pantoprazole, edetate disodium (1 mg), and sodium hydroxide to adjust pH.
Last reviewed on RxList: 5/5/2008




Protonix I.V. Drug Description
PROTONIX® I.V.
(pantoprazole sodium) for Injection
DRUG DESCRIPTION
The active ingredient in PROTONIX® I.V. (pantoprazole sodium) for Injection
is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]
sulfinyl]- 1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C16H14F2N3NaO4S,
with a molecular weight of 405.4. The structural formula is:







Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. The reconstituted solution of PROTONIX I.V. for Injection is in the pH range 9.0 to 10.5.
PROTONIX I.V. for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing pantoprazole sodium, equivalent to 40 mg of pantoprazole, edetate disodium (1 mg), and sodium hydroxide to adjust pH.
Last reviewed on RxList: 5/5/2008




Protonix I.V. Drug Description
PROTONIX® I.V.
(pantoprazole sodium) for Injection
DRUG DESCRIPTION
The active ingredient in PROTONIX® I.V. (pantoprazole sodium) for Injection
is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]
sulfinyl]- 1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C16H14F2N3NaO4S,
with a molecular weight of 405.4. The structural formula is:







Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. The reconstituted solution of PROTONIX I.V. for Injection is in the pH range 9.0 to 10.5.
PROTONIX I.V. for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing pantoprazole sodium, equivalent to 40 mg of pantoprazole, edetate disodium (1 mg), and sodium hydroxide to adjust pH.
Last reviewed on RxList: 5/5/2008




Protonix I.V. Drug Description
PROTONIX® I.V.
(pantoprazole sodium) for Injection
DRUG DESCRIPTION
The active ingredient in PROTONIX® I.V. (pantoprazole sodium) for Injection
is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]
sulfinyl]- 1H-benzimidazole, a compound that inhibits gastric acid secretion.
Its empirical formula is C16H14F2N3NaO4S,
with a molecular weight of 405.4. The structural formula is:







Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. The stability of the compound in aqueous solution is pH-dependent. The rate of degradation increases with decreasing pH. The reconstituted solution of PROTONIX I.V. for Injection is in the pH range 9.0 to 10.5.
PROTONIX I.V. for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing pantoprazole sodium, equivalent to 40 mg of pantoprazole, edetate disodium (1 mg), and sodium hydroxide to adjust pH.
Last reviewed on RxList: 5/5/2008





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Comprehensive and trusted information about Pantoprazole sodium - plus advice on 24,000 other FDA approved drugs and medications from Drugs.com. Pantoprazole sodium patient advice including side effects


Pantoprazole Sodium professional patient advice. Specific and up to date information about Pantoprazole Sodium. Complete Pantoprazole Sodium information from Drugs.com


... as drug screenings (pantoprazole can cause a false positive for THC, the psychoactive component of cannabis). [citation needed] The active ingredient in PROTONIX (pantoprazole sodium ... Pantoprazole - Wikipedia, the free encyclopedia


Pantoprazole sodium (Protonix) is a drug used to treat conditions such as gastroesophageal reflux disease. This eMedTV article discusses how this medication works, what ... Pantoprazole


pan·to·pra·zole sodium (p n-t pr-z l) n. A proton pump inhibitor drug used primarily to treat erosive esophagitis and hypersecretory conditions such as Zollinger-Ellison syndrome. pantoprazole sodium - definition of pantoprazole sodium in the ...


PROTONIX (pantoprazole sodium) is supplied as a for delayed-release oral suspension, available in one strength (40 mg), and as a delayed-release tablet, available in two ... Protonix (Pantoprazole) Drug Information: Uses, Side Effects, Drug ...


Pantoprazole Sodium is a proton pump inhibitor (PPI) used to treat ulcers, gastroesophageal reflux disease (GERD), erosive esophagitis, or Zollinger-Ellison syndrome. Side ... Pantoprazole Sodium - drugstore.com. Low prices, side effects ...


Pantoprazole (pantoprazole sodium) is sold under several brand names, including Protonix, Pantopan, Astropan, Controloc, Pantecta, Pantozol, Protium, Pantor, and Pantoloc. Each ... Pantoprazole - Medpedia


Equanil side effects, dosage, and drug interactions. All accurate, up-to-date information is written for the consumer by healthcare professionals. Equanil Oral Uses and How to Use


Pantoprazole Sodium (Protonix ®, Wyeth-Ayerst Pharmaceuticals) Drug Class: Proton Pump Inhibitor. Uses: Pantoprazole’s labeled indication is for the short-term treatment (no more ... Pantoprazole Sodium





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