Reviews Oxybutynin Chloride Extended Release Tablets


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Ditropan XL Drug Description
DITROPAN XL®
(oxybutynin chloride) Extended Release Tablets
DRUG DESCRIPTION



What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:

hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.

Less serious...
Read All Potential Side Effects for Ditropan XL »




DITROPAN XL® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. Each DITROPAN XL Extended Release Tablet contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R- and S-enantiomers.
Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate
hydrochloride. The empirical formula of oxybutynin chloride is C22H31NO3•HCl.
Its structural formula is:








Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.
DITROPAN XL also contains the following inert ingredients: cellulose acetate, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyethylene oxide, synthetic iron oxides, titanium dioxide, polysorbate 80, sodium chloride, and butylated hydroxytoluene.
System Components and Performance
DITROPAN XL uses osmotic pressure to deliver oxybutynin chloride at a controlled
rate over approximately 24 hours. The system, which resembles a conventional
tablet in appearance, comprises an osmotically active bilayer core surrounded
by a semipermeable membrane. The bilayer core is composed of a drug layer containing
the drug and excipients, and a push layer containing osmotically active components.
There is a precision-laser drilled orifice in the semipermeable membrane on
the drug-layer side of the tablet. In an aqueous environment, such as the gastrointestinal
tract, water permeates through the membrane into the tablet core, causing the
drug to go into suspension and the push layer to expand. This expansion pushes
the suspended drug out through the orifice. The semipermeable membrane controls
the rate at which water permeates into the tablet core, which in turn controls
the rate of drug delivery. The controlled rate of drug delivery into the gastrointestinal
lumen is thus independent of pH or gastrointestinal motility. The function of
DITROPAN XL depends on the existence of an osmotic gradient between the contents
of the bilayer core and the fluid in the gastrointestinal tract. Since the osmotic
gradient remains constant, drug delivery remains essentially constant. The biologically
inert components of the tablet remain intact during gastrointestinal transit
and are eliminated in the feces as an insoluble shell.Last reviewed on RxList: 8/4/2009




Ditropan XL Drug Description
DITROPAN XL®
(oxybutynin chloride) Extended Release Tablets
DRUG DESCRIPTION



What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:

hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.

Less serious...
Read All Potential Side Effects for Ditropan XL »




DITROPAN XL® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. Each DITROPAN XL Extended Release Tablet contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R- and S-enantiomers.
Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate
hydrochloride. The empirical formula of oxybutynin chloride is C22H31NO3•HCl.
Its structural formula is:








Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.
DITROPAN XL also contains the following inert ingredients: cellulose acetate, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyethylene oxide, synthetic iron oxides, titanium dioxide, polysorbate 80, sodium chloride, and butylated hydroxytoluene.
System Components and Performance
DITROPAN XL uses osmotic pressure to deliver oxybutynin chloride at a controlled
rate over approximately 24 hours. The system, which resembles a conventional
tablet in appearance, comprises an osmotically active bilayer core surrounded
by a semipermeable membrane. The bilayer core is composed of a drug layer containing
the drug and excipients, and a push layer containing osmotically active components.
There is a precision-laser drilled orifice in the semipermeable membrane on
the drug-layer side of the tablet. In an aqueous environment, such as the gastrointestinal
tract, water permeates through the membrane into the tablet core, causing the
drug to go into suspension and the push layer to expand. This expansion pushes
the suspended drug out through the orifice. The semipermeable membrane controls
the rate at which water permeates into the tablet core, which in turn controls
the rate of drug delivery. The controlled rate of drug delivery into the gastrointestinal
lumen is thus independent of pH or gastrointestinal motility. The function of
DITROPAN XL depends on the existence of an osmotic gradient between the contents
of the bilayer core and the fluid in the gastrointestinal tract. Since the osmotic
gradient remains constant, drug delivery remains essentially constant. The biologically
inert components of the tablet remain intact during gastrointestinal transit
and are eliminated in the feces as an insoluble shell.Last reviewed on RxList: 8/4/2009




Ditropan XL Drug Description
DITROPAN XL®
(oxybutynin chloride) Extended Release Tablets
DRUG DESCRIPTION



What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:

hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.

Less serious...
Read All Potential Side Effects for Ditropan XL »




DITROPAN XL® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. Each DITROPAN XL Extended Release Tablet contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R- and S-enantiomers.
Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate
hydrochloride. The empirical formula of oxybutynin chloride is C22H31NO3•HCl.
Its structural formula is:








Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.
DITROPAN XL also contains the following inert ingredients: cellulose acetate, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyethylene oxide, synthetic iron oxides, titanium dioxide, polysorbate 80, sodium chloride, and butylated hydroxytoluene.
System Components and Performance
DITROPAN XL uses osmotic pressure to deliver oxybutynin chloride at a controlled
rate over approximately 24 hours. The system, which resembles a conventional
tablet in appearance, comprises an osmotically active bilayer core surrounded
by a semipermeable membrane. The bilayer core is composed of a drug layer containing
the drug and excipients, and a push layer containing osmotically active components.
There is a precision-laser drilled orifice in the semipermeable membrane on
the drug-layer side of the tablet. In an aqueous environment, such as the gastrointestinal
tract, water permeates through the membrane into the tablet core, causing the
drug to go into suspension and the push layer to expand. This expansion pushes
the suspended drug out through the orifice. The semipermeable membrane controls
the rate at which water permeates into the tablet core, which in turn controls
the rate of drug delivery. The controlled rate of drug delivery into the gastrointestinal
lumen is thus independent of pH or gastrointestinal motility. The function of
DITROPAN XL depends on the existence of an osmotic gradient between the contents
of the bilayer core and the fluid in the gastrointestinal tract. Since the osmotic
gradient remains constant, drug delivery remains essentially constant. The biologically
inert components of the tablet remain intact during gastrointestinal transit
and are eliminated in the feces as an insoluble shell.Last reviewed on RxList: 8/4/2009




Ditropan XL Drug Description
DITROPAN XL®
(oxybutynin chloride) Extended Release Tablets
DRUG DESCRIPTION



What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:

hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.

Less serious...
Read All Potential Side Effects for Ditropan XL »




DITROPAN XL® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. Each DITROPAN XL Extended Release Tablet contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R- and S-enantiomers.
Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate
hydrochloride. The empirical formula of oxybutynin chloride is C22H31NO3•HCl.
Its structural formula is:








Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.
DITROPAN XL also contains the following inert ingredients: cellulose acetate, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyethylene oxide, synthetic iron oxides, titanium dioxide, polysorbate 80, sodium chloride, and butylated hydroxytoluene.
System Components and Performance
DITROPAN XL uses osmotic pressure to deliver oxybutynin chloride at a controlled
rate over approximately 24 hours. The system, which resembles a conventional
tablet in appearance, comprises an osmotically active bilayer core surrounded
by a semipermeable membrane. The bilayer core is composed of a drug layer containing
the drug and excipients, and a push layer containing osmotically active components.
There is a precision-laser drilled orifice in the semipermeable membrane on
the drug-layer side of the tablet. In an aqueous environment, such as the gastrointestinal
tract, water permeates through the membrane into the tablet core, causing the
drug to go into suspension and the push layer to expand. This expansion pushes
the suspended drug out through the orifice. The semipermeable membrane controls
the rate at which water permeates into the tablet core, which in turn controls
the rate of drug delivery. The controlled rate of drug delivery into the gastrointestinal
lumen is thus independent of pH or gastrointestinal motility. The function of
DITROPAN XL depends on the existence of an osmotic gradient between the contents
of the bilayer core and the fluid in the gastrointestinal tract. Since the osmotic
gradient remains constant, drug delivery remains essentially constant. The biologically
inert components of the tablet remain intact during gastrointestinal transit
and are eliminated in the feces as an insoluble shell.Last reviewed on RxList: 8/4/2009




Ditropan XL Drug Description
DITROPAN XL®
(oxybutynin chloride) Extended Release Tablets
DRUG DESCRIPTION



What are the possible side effects of oxybutynin (Ditropan, Ditropan XL, Urotrol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:

hot, dry skin and extreme thirst;
severe stomach pain or constipation;
pain or burning when you urinate; or
urinating less than usual or not at all.

Less serious...
Read All Potential Side Effects for Ditropan XL »




DITROPAN XL® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. Each DITROPAN XL Extended Release Tablet contains 5 mg, 10 mg, or 15 mg of oxybutynin chloride USP, formulated as a once-a-day controlled-release tablet for oral administration. Oxybutynin chloride is administered as a racemate of R- and S-enantiomers.
Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate
hydrochloride. The empirical formula of oxybutynin chloride is C22H31NO3•HCl.
Its structural formula is:








Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.
DITROPAN XL also contains the following inert ingredients: cellulose acetate, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyethylene oxide, synthetic iron oxides, titanium dioxide, polysorbate 80, sodium chloride, and butylated hydroxytoluene.
System Components and Performance
DITROPAN XL uses osmotic pressure to deliver oxybutynin chloride at a controlled
rate over approximately 24 hours. The system, which resembles a conventional
tablet in appearance, comprises an osmotically active bilayer core surrounded
by a semipermeable membrane. The bilayer core is composed of a drug layer containing
the drug and excipients, and a push layer containing osmotically active components.
There is a precision-laser drilled orifice in the semipermeable membrane on
the drug-layer side of the tablet. In an aqueous environment, such as the gastrointestinal
tract, water permeates through the membrane into the tablet core, causing the
drug to go into suspension and the push layer to expand. This expansion pushes
the suspended drug out through the orifice. The semipermeable membrane controls
the rate at which water permeates into the tablet core, which in turn controls
the rate of drug delivery. The controlled rate of drug delivery into the gastrointestinal
lumen is thus independent of pH or gastrointestinal motility. The function of
DITROPAN XL depends on the existence of an osmotic gradient between the contents
of the bilayer core and the fluid in the gastrointestinal tract. Since the osmotic
gradient remains constant, drug delivery remains essentially constant. The biologically
inert components of the tablet remain intact during gastrointestinal transit
and are eliminated in the feces as an insoluble shell.Last reviewed on RxList: 8/4/2009





Other reviews about Oxybutynin Chloride Extended Release Tablets on wordpress

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Oxybutynin (Oral Route)     Other Names:   Ditropan®, Ditropan® Syrup, Ditropan® XL   Description   Oxybutynin belongs to the group of medicines called antispasmodics. It helps decrease muscle spasms of the bladder and the frequent […]


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Other reviews about Oxybutynin Chloride Extended Release Tablets on web:

Learn about the prescription medication Ditropan XL (Oxybutynin Chloride Extended Release Tablets), drug uses, dosage, side effects, drug interactions, warnings, reviews and ... Ditropan XL (Oxybutynin Chloride Extended Release Tablets) Drug ...


Oxybutynin Chloride extended-release tablets are also indicated in the treatment of pediatric patients aged 6 years and older with symptoms of detrusor overactivity associated with ... Oxybutynin Chloride Official FDA information, side effects and uses.


Ditropan XL (oxybutynin chloride) Extended Release Tablets. Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) -- February 2008 Ditropan XL (oxybutynin chloride) Extended Release Tablets


Ditropan ® XL (oxybutynin chloride) Extended Release Tablets DESCRIPTION DITROPAN ® XL (oxybutynin chloride) is an antispasmodic, anticholinergic agent. (oxybutynin chloride) Extended Release Tablets


Keep Oxybutynin chloride in a tightly closed container and store it at room temperature. Protect the syrup from direct light. Protect the extended-release tablets from moisture and ... Oxybutynin chloride patient advice including side effects


The objective of this study was to investigate the single-dose relative bioavailability of Mylan's oxybutynin chloride extended-release tablets to ALZA's Ditropan XL® tablets ... Food Study of Oxybutynin Chloride Extended-Release Tablets 5 mg ...


OXYBUTYNIN CHLORIDE EXTENDED RELEASE TABLETS, 5 MG, 10 MG and 15 MG DESCRIPTION Oxybutynin chloride is an antispasmodic, anticholinergic agent. Each oxybutynin chloride ... OXYBUTYNIN CHLORIDE EXTENDED RELEASE TABLETS,


NDA 20-897/S-013 Page 3 DITROPAN XL  (oxybutynin chloride) Extended Release Tablets DESCRIPTION DITROPAN XL ® (oxybutynin chloride) is an antispasmodic, anticholinergic agent. DITROPAN XL (oxybutynin chloride) Extended Release Tablets


DITROPAN XL (oxybutynin chloride) Extended Release Tablets DITROPAN XL (oxybutynin chloride) Extended Release Tablets, Ortho-McNeil-Janssen Pharmaceuticals, Inc. DITROPAN XL (oxybutynin chloride) Extended Release Tablets, Ortho ...


Oxybutynin Chloride Oral tablet (below) Oxybutynin oral syrup; Oxybutynin Chloride Oral tablet, extended-release; Oxybutynin skin patch; Oxybutynin Chloride Oral solution Oxybutynin: Information from Answers.com





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