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Mustargen Drug Description
MUSTARGEN®
(mechlorethamine HCl) for Injection

WARNINGS
MUSTARGEN (Mechlorethamine HCl) should be administered only under the supervision
of a physician who is experienced in the use of cancer chemotherapeutic agents.
This drug is HIGHLY TOXIC and both powder and solution must be handled
and administered with care. Inhalation of dust or vapors and contact with skin
or mucous membranes, especially those of the eyes, must be avoided. Avoid exposure
during pregnancy. Due to the toxic properties of mechlorethamine (e.g., corrosivity,
carcinogenicity, mutagenicity, teratogenicity), special handling procedures
should be reviewed prior to handling and followed diligently.
Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

DRUG DESCRIPTION



What are the possible side effects of mechlorethamine (Mustargen)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
blood in the urine;
black or tarry stools;
signs of infection such as fever; chills, or sore throat;
joint pain and stiffness similar to gout (high levels of uric acid in the...
Read All Potential Side Effects for Mustargen »




MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a light yellow brown, crystalline, hygroscopic powder that is very soluble in water and also soluble in alcohol.
Mechlorethamine hydrochloride is designated chemically as 2-chloro-N-(2-chloroethyl)-N-methylethanamine
hydrochloride. The molecular weight is 192.52 and the melting point is 108-111°C.
The empirical formula is C5H11Cl2N•HCl, and
the structural formula is: CH3N(CH2CH2Cl)2•HCl.
Trituration of MUSTARGEN is a sterile, light yellow brown crystalline powder for injection by the intravenous or intracavitary routes after dissolution. Each vial of MUSTARGEN contains 10 mg of mechlorethamine hydrochloride triturated with sodium chloride q.s. 100 mg. When dissolved with 10 mL Sterile Water for Injection or 0.9% Sodium Chloride Injection, the resulting solution has a pH of 3-5 at a concentration of 1 mg mechlorethamine HCl per mL.
Last reviewed on RxList: 5/21/2009




Mustargen Drug Description
MUSTARGEN®
(mechlorethamine HCl) for Injection

WARNINGS
MUSTARGEN (Mechlorethamine HCl) should be administered only under the supervision
of a physician who is experienced in the use of cancer chemotherapeutic agents.
This drug is HIGHLY TOXIC and both powder and solution must be handled
and administered with care. Inhalation of dust or vapors and contact with skin
or mucous membranes, especially those of the eyes, must be avoided. Avoid exposure
during pregnancy. Due to the toxic properties of mechlorethamine (e.g., corrosivity,
carcinogenicity, mutagenicity, teratogenicity), special handling procedures
should be reviewed prior to handling and followed diligently.
Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

DRUG DESCRIPTION



What are the possible side effects of mechlorethamine (Mustargen)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
blood in the urine;
black or tarry stools;
signs of infection such as fever; chills, or sore throat;
joint pain and stiffness similar to gout (high levels of uric acid in the...
Read All Potential Side Effects for Mustargen »




MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a light yellow brown, crystalline, hygroscopic powder that is very soluble in water and also soluble in alcohol.
Mechlorethamine hydrochloride is designated chemically as 2-chloro-N-(2-chloroethyl)-N-methylethanamine
hydrochloride. The molecular weight is 192.52 and the melting point is 108-111°C.
The empirical formula is C5H11Cl2N•HCl, and
the structural formula is: CH3N(CH2CH2Cl)2•HCl.
Trituration of MUSTARGEN is a sterile, light yellow brown crystalline powder for injection by the intravenous or intracavitary routes after dissolution. Each vial of MUSTARGEN contains 10 mg of mechlorethamine hydrochloride triturated with sodium chloride q.s. 100 mg. When dissolved with 10 mL Sterile Water for Injection or 0.9% Sodium Chloride Injection, the resulting solution has a pH of 3-5 at a concentration of 1 mg mechlorethamine HCl per mL.
Last reviewed on RxList: 5/21/2009




Mustargen Drug Description
MUSTARGEN®
(mechlorethamine HCl) for Injection

WARNINGS
MUSTARGEN (Mechlorethamine HCl) should be administered only under the supervision
of a physician who is experienced in the use of cancer chemotherapeutic agents.
This drug is HIGHLY TOXIC and both powder and solution must be handled
and administered with care. Inhalation of dust or vapors and contact with skin
or mucous membranes, especially those of the eyes, must be avoided. Avoid exposure
during pregnancy. Due to the toxic properties of mechlorethamine (e.g., corrosivity,
carcinogenicity, mutagenicity, teratogenicity), special handling procedures
should be reviewed prior to handling and followed diligently.
Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

DRUG DESCRIPTION



What are the possible side effects of mechlorethamine (Mustargen)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
blood in the urine;
black or tarry stools;
signs of infection such as fever; chills, or sore throat;
joint pain and stiffness similar to gout (high levels of uric acid in the...
Read All Potential Side Effects for Mustargen »




MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a light yellow brown, crystalline, hygroscopic powder that is very soluble in water and also soluble in alcohol.
Mechlorethamine hydrochloride is designated chemically as 2-chloro-N-(2-chloroethyl)-N-methylethanamine
hydrochloride. The molecular weight is 192.52 and the melting point is 108-111°C.
The empirical formula is C5H11Cl2N•HCl, and
the structural formula is: CH3N(CH2CH2Cl)2•HCl.
Trituration of MUSTARGEN is a sterile, light yellow brown crystalline powder for injection by the intravenous or intracavitary routes after dissolution. Each vial of MUSTARGEN contains 10 mg of mechlorethamine hydrochloride triturated with sodium chloride q.s. 100 mg. When dissolved with 10 mL Sterile Water for Injection or 0.9% Sodium Chloride Injection, the resulting solution has a pH of 3-5 at a concentration of 1 mg mechlorethamine HCl per mL.
Last reviewed on RxList: 5/21/2009




Mustargen Drug Description
MUSTARGEN®
(mechlorethamine HCl) for Injection

WARNINGS
MUSTARGEN (Mechlorethamine HCl) should be administered only under the supervision
of a physician who is experienced in the use of cancer chemotherapeutic agents.
This drug is HIGHLY TOXIC and both powder and solution must be handled
and administered with care. Inhalation of dust or vapors and contact with skin
or mucous membranes, especially those of the eyes, must be avoided. Avoid exposure
during pregnancy. Due to the toxic properties of mechlorethamine (e.g., corrosivity,
carcinogenicity, mutagenicity, teratogenicity), special handling procedures
should be reviewed prior to handling and followed diligently.
Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

DRUG DESCRIPTION



What are the possible side effects of mechlorethamine (Mustargen)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
blood in the urine;
black or tarry stools;
signs of infection such as fever; chills, or sore throat;
joint pain and stiffness similar to gout (high levels of uric acid in the...
Read All Potential Side Effects for Mustargen »




MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a light yellow brown, crystalline, hygroscopic powder that is very soluble in water and also soluble in alcohol.
Mechlorethamine hydrochloride is designated chemically as 2-chloro-N-(2-chloroethyl)-N-methylethanamine
hydrochloride. The molecular weight is 192.52 and the melting point is 108-111°C.
The empirical formula is C5H11Cl2N•HCl, and
the structural formula is: CH3N(CH2CH2Cl)2•HCl.
Trituration of MUSTARGEN is a sterile, light yellow brown crystalline powder for injection by the intravenous or intracavitary routes after dissolution. Each vial of MUSTARGEN contains 10 mg of mechlorethamine hydrochloride triturated with sodium chloride q.s. 100 mg. When dissolved with 10 mL Sterile Water for Injection or 0.9% Sodium Chloride Injection, the resulting solution has a pH of 3-5 at a concentration of 1 mg mechlorethamine HCl per mL.
Last reviewed on RxList: 5/21/2009




Mustargen Drug Description
MUSTARGEN®
(mechlorethamine HCl) for Injection

WARNINGS
MUSTARGEN (Mechlorethamine HCl) should be administered only under the supervision
of a physician who is experienced in the use of cancer chemotherapeutic agents.
This drug is HIGHLY TOXIC and both powder and solution must be handled
and administered with care. Inhalation of dust or vapors and contact with skin
or mucous membranes, especially those of the eyes, must be avoided. Avoid exposure
during pregnancy. Due to the toxic properties of mechlorethamine (e.g., corrosivity,
carcinogenicity, mutagenicity, teratogenicity), special handling procedures
should be reviewed prior to handling and followed diligently.
Extravasation of the drug into subcutaneous tissues results in a painful inflammation. The area usually becomes indurated and sloughing may occur. If leakage of drug is obvious, prompt infiltration of the area with sterile isotonic sodium thiosulfate (1/6 molar) and application of an ice compress for 6 to 12 hours may minimize the local reaction. For a 1/6 molar solution of sodium thiosulfate, use 4.14 g of sodium thiosulfate per 100 mL of Sterile Water for Injection or 2.64 g of anhydrous sodium thiosulfate per 100 mL or dilute 4 mL of Sodium Thiosulfate Injection (10%) with 6 mL of Sterile Water for Injection.

DRUG DESCRIPTION



What are the possible side effects of mechlorethamine (Mustargen)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of your throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
blood in the urine;
black or tarry stools;
signs of infection such as fever; chills, or sore throat;
joint pain and stiffness similar to gout (high levels of uric acid in the...
Read All Potential Side Effects for Mustargen »




MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a light yellow brown, crystalline, hygroscopic powder that is very soluble in water and also soluble in alcohol.
Mechlorethamine hydrochloride is designated chemically as 2-chloro-N-(2-chloroethyl)-N-methylethanamine
hydrochloride. The molecular weight is 192.52 and the melting point is 108-111°C.
The empirical formula is C5H11Cl2N•HCl, and
the structural formula is: CH3N(CH2CH2Cl)2•HCl.
Trituration of MUSTARGEN is a sterile, light yellow brown crystalline powder for injection by the intravenous or intracavitary routes after dissolution. Each vial of MUSTARGEN contains 10 mg of mechlorethamine hydrochloride triturated with sodium chloride q.s. 100 mg. When dissolved with 10 mL Sterile Water for Injection or 0.9% Sodium Chloride Injection, the resulting solution has a pH of 3-5 at a concentration of 1 mg mechlorethamine HCl per mL.
Last reviewed on RxList: 5/21/2009





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Other reviews about Mustargen on web:

Learn about the prescription medication Mustargen (Mechlorethamine HCl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Mustargen (Mechlorethamine HCl) Drug Information: Uses, Side ...


All about Mustargen. View complete and up to date Mustargen information - part of the Drugs.com trusted medication database. Mustargen Facts and Comparisons at Drugs.com


Accurate, FDA approved Mustargen information for healthcare professionals and patients - brought to you by Drugs.com. Mustargen Official FDA information, side effects and uses.


Mustargen is the trade name for Mechlorethamine. Nitrogen Mustard, Mustine, and Mechlorethamine Hydrochloride are other names for Mustargen. Mustargen is an anti-cancer ... Mustargen, Mechlorethamine - Chemotherapy Drugs, Chemo Drug Side ...


(Redirected from Mustargen) ... The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas. Nitrogen mustard - Wikipedia, the free encyclopedia


Information for the Physician. Topical nitrogen mustard (Mustargen, mechlorethamine) can be used either mixed in Aquaphor ointment by a trained pharmacist or compounded in water by ... Topical Mustargen - Resources - Patient Care - Multidisciplinary ...


A description of mustargen / mechlorethamine, a chemotherapy drug used in lymphoma treatment Chemotherapy - Mustargen


Description. Mechlorethamine (me-klor-ETH-a-meen) belongs to the group of medicines called alkylating agents. It is used to treat some kinds of cancer as well as some noncancerous ... Mustargen Resource Site


Find patient medical information for Mustargen Inj on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Mustargen Inj : Uses, Side Effects, Interactions, Pictures ...


What is topical nitrogen mustard? Manufactured by Merck & Co., topical nitrogen mustard (mechlorethamine), also called Mustargen™ or NM, is a commonly used topical chemotherapy ... Topical Nitrogen Mustard (Mustargen) - Educational Resources ...





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