Reviews Morphine Sulfate Extended-Release


No reviews yet.

Kadian Drug Description
Kadian
(morphine sulfate) Extended-Release Capsules
CII (Schedule II controlled substance)
Kadian® 20 mg Capsules
Kadian® 30 mg Capsules
Kadian® 50 mg Capsules
Kadian® 60 mg Capsules
Kadian® 80 mg Capsules
Kadian® 100 mg Capsules

WARNING
Kadian® contains morphine sulfate, an opioid agonist and a Schedule II
controlled substance, with an abuse liability similar to other opioid analgesics.
Kadian® can be abused in a manner similar to other opioid agonists, legal
or illicit. This should be considered when prescribing or dispensing Kadian®
in situations where the physician or pharmacist is concerned about an increased
risk of misuse, abuse or diversion.
Kadian® capsules are an extended-release oral formulation of morphine sulfate
indicated for the management of moderate to severe pain when a continuous, around-the-clock
opioid analgesic is needed for an extended period of time.
Kadian® Capsules are NOT for use as a prn analgesic.

Kadian® 100 mg Capsules ARE FOR USE IN OPIOID-TOLERANT PATIENTS ONLY.
Ingestion of these capsules or of the pellets within the capsules may cause
fatal respiratory depression when administered to patients not already tolerant
to high doses of opioids. KADIAN CAPSULES ARE TO BE SWALLOWED WHOLE
OR THE CONTENTS OF THE CAPSULES SPRINKLED ON APPLE SAUCE. THE PELLETS IN THE
CAPSULES ARE NOT TO BE CHEWED, CRUSHED, OR DISSOLVED DUE TO THE RISK OF RAPID
RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF MORPHINE.

DRUG DESCRIPTION



What are the possible side effects of morphine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to...
Read All Potential Side Effects for Kadian »




Kadian® (morphine sulfate) capsules are an opioid analgesic supplied in
20 mg, 30 mg, 50 mg, 60 mg, 80 mg, and 100 mg strengths for oral administration.

Chemically, morphine sulfate is 7,8-didehydro-4,5 α-
epoxy-17-methyl-morphinan-3,6 α- diol sulfate (2:1)
(salt) pentahydrate and has the following structural formula:








Morphine sulfate is an odorless, white, crystalline powder with
a bitter taste and a molecular weight of 758 (as the sulfate). It has a solubility
of 1 in 21 parts of water and 1 in 1000 parts of alcohol, but is practically
insoluble in chloroform or ether. The octanol: water partition coefficient
of morphine is 1.42 at physiologic pH and the pKb is 7.9 for the
tertiary nitrogen (mostly ionized at pH 7.4).
Each Kadian® extended-release capsule contains either 20 mg, 30 mg, 50
mg, 60 mg, 80 mg, or 100 mg of Morphine Sulfate USP and the following inactive
ingredients common to all strengths: hypromellose, ethylcellulose, methacrylic
acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and
sucrose. The capsule shells contain gelatin, silicon dioxide, sodium lauryl
sulfate, titanium dioxide, and black ink, D&C yellow #10 (20 mg), FD&C
red #3, FD&C blue #1 (30 mg), D&C red #28, FD&C red #40, FD&C
blue #1 (50 mg), D&C red #28, FD&C red #40, FD&C blue #1 (60 mg),
FD&C blue #1, FD&C red #40, FD&C yellow #6 (80 mg), D&C yellow
#10, FD&C blue #1 (100 mg).
Last reviewed on RxList: 1/14/2008




Kadian Drug Description
Kadian
(morphine sulfate) Extended-Release Capsules
CII (Schedule II controlled substance)
Kadian® 20 mg Capsules
Kadian® 30 mg Capsules
Kadian® 50 mg Capsules
Kadian® 60 mg Capsules
Kadian® 80 mg Capsules
Kadian® 100 mg Capsules

WARNING
Kadian® contains morphine sulfate, an opioid agonist and a Schedule II
controlled substance, with an abuse liability similar to other opioid analgesics.
Kadian® can be abused in a manner similar to other opioid agonists, legal
or illicit. This should be considered when prescribing or dispensing Kadian®
in situations where the physician or pharmacist is concerned about an increased
risk of misuse, abuse or diversion.
Kadian® capsules are an extended-release oral formulation of morphine sulfate
indicated for the management of moderate to severe pain when a continuous, around-the-clock
opioid analgesic is needed for an extended period of time.
Kadian® Capsules are NOT for use as a prn analgesic.

Kadian® 100 mg Capsules ARE FOR USE IN OPIOID-TOLERANT PATIENTS ONLY.
Ingestion of these capsules or of the pellets within the capsules may cause
fatal respiratory depression when administered to patients not already tolerant
to high doses of opioids. KADIAN CAPSULES ARE TO BE SWALLOWED WHOLE
OR THE CONTENTS OF THE CAPSULES SPRINKLED ON APPLE SAUCE. THE PELLETS IN THE
CAPSULES ARE NOT TO BE CHEWED, CRUSHED, OR DISSOLVED DUE TO THE RISK OF RAPID
RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF MORPHINE.

DRUG DESCRIPTION



What are the possible side effects of morphine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to...
Read All Potential Side Effects for Kadian »




Kadian® (morphine sulfate) capsules are an opioid analgesic supplied in
20 mg, 30 mg, 50 mg, 60 mg, 80 mg, and 100 mg strengths for oral administration.

Chemically, morphine sulfate is 7,8-didehydro-4,5 α-
epoxy-17-methyl-morphinan-3,6 α- diol sulfate (2:1)
(salt) pentahydrate and has the following structural formula:








Morphine sulfate is an odorless, white, crystalline powder with
a bitter taste and a molecular weight of 758 (as the sulfate). It has a solubility
of 1 in 21 parts of water and 1 in 1000 parts of alcohol, but is practically
insoluble in chloroform or ether. The octanol: water partition coefficient
of morphine is 1.42 at physiologic pH and the pKb is 7.9 for the
tertiary nitrogen (mostly ionized at pH 7.4).
Each Kadian® extended-release capsule contains either 20 mg, 30 mg, 50
mg, 60 mg, 80 mg, or 100 mg of Morphine Sulfate USP and the following inactive
ingredients common to all strengths: hypromellose, ethylcellulose, methacrylic
acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and
sucrose. The capsule shells contain gelatin, silicon dioxide, sodium lauryl
sulfate, titanium dioxide, and black ink, D&C yellow #10 (20 mg), FD&C
red #3, FD&C blue #1 (30 mg), D&C red #28, FD&C red #40, FD&C
blue #1 (50 mg), D&C red #28, FD&C red #40, FD&C blue #1 (60 mg),
FD&C blue #1, FD&C red #40, FD&C yellow #6 (80 mg), D&C yellow
#10, FD&C blue #1 (100 mg).
Last reviewed on RxList: 1/14/2008




Kadian Drug Description
Kadian
(morphine sulfate) Extended-Release Capsules
CII (Schedule II controlled substance)
Kadian® 20 mg Capsules
Kadian® 30 mg Capsules
Kadian® 50 mg Capsules
Kadian® 60 mg Capsules
Kadian® 80 mg Capsules
Kadian® 100 mg Capsules

WARNING
Kadian® contains morphine sulfate, an opioid agonist and a Schedule II
controlled substance, with an abuse liability similar to other opioid analgesics.
Kadian® can be abused in a manner similar to other opioid agonists, legal
or illicit. This should be considered when prescribing or dispensing Kadian®
in situations where the physician or pharmacist is concerned about an increased
risk of misuse, abuse or diversion.
Kadian® capsules are an extended-release oral formulation of morphine sulfate
indicated for the management of moderate to severe pain when a continuous, around-the-clock
opioid analgesic is needed for an extended period of time.
Kadian® Capsules are NOT for use as a prn analgesic.

Kadian® 100 mg Capsules ARE FOR USE IN OPIOID-TOLERANT PATIENTS ONLY.
Ingestion of these capsules or of the pellets within the capsules may cause
fatal respiratory depression when administered to patients not already tolerant
to high doses of opioids. KADIAN CAPSULES ARE TO BE SWALLOWED WHOLE
OR THE CONTENTS OF THE CAPSULES SPRINKLED ON APPLE SAUCE. THE PELLETS IN THE
CAPSULES ARE NOT TO BE CHEWED, CRUSHED, OR DISSOLVED DUE TO THE RISK OF RAPID
RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF MORPHINE.

DRUG DESCRIPTION



What are the possible side effects of morphine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to...
Read All Potential Side Effects for Kadian »




Kadian® (morphine sulfate) capsules are an opioid analgesic supplied in
20 mg, 30 mg, 50 mg, 60 mg, 80 mg, and 100 mg strengths for oral administration.

Chemically, morphine sulfate is 7,8-didehydro-4,5 α-
epoxy-17-methyl-morphinan-3,6 α- diol sulfate (2:1)
(salt) pentahydrate and has the following structural formula:








Morphine sulfate is an odorless, white, crystalline powder with
a bitter taste and a molecular weight of 758 (as the sulfate). It has a solubility
of 1 in 21 parts of water and 1 in 1000 parts of alcohol, but is practically
insoluble in chloroform or ether. The octanol: water partition coefficient
of morphine is 1.42 at physiologic pH and the pKb is 7.9 for the
tertiary nitrogen (mostly ionized at pH 7.4).
Each Kadian® extended-release capsule contains either 20 mg, 30 mg, 50
mg, 60 mg, 80 mg, or 100 mg of Morphine Sulfate USP and the following inactive
ingredients common to all strengths: hypromellose, ethylcellulose, methacrylic
acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and
sucrose. The capsule shells contain gelatin, silicon dioxide, sodium lauryl
sulfate, titanium dioxide, and black ink, D&C yellow #10 (20 mg), FD&C
red #3, FD&C blue #1 (30 mg), D&C red #28, FD&C red #40, FD&C
blue #1 (50 mg), D&C red #28, FD&C red #40, FD&C blue #1 (60 mg),
FD&C blue #1, FD&C red #40, FD&C yellow #6 (80 mg), D&C yellow
#10, FD&C blue #1 (100 mg).
Last reviewed on RxList: 1/14/2008




Kadian Drug Description
Kadian
(morphine sulfate) Extended-Release Capsules
CII (Schedule II controlled substance)
Kadian® 20 mg Capsules
Kadian® 30 mg Capsules
Kadian® 50 mg Capsules
Kadian® 60 mg Capsules
Kadian® 80 mg Capsules
Kadian® 100 mg Capsules

WARNING
Kadian® contains morphine sulfate, an opioid agonist and a Schedule II
controlled substance, with an abuse liability similar to other opioid analgesics.
Kadian® can be abused in a manner similar to other opioid agonists, legal
or illicit. This should be considered when prescribing or dispensing Kadian®
in situations where the physician or pharmacist is concerned about an increased
risk of misuse, abuse or diversion.
Kadian® capsules are an extended-release oral formulation of morphine sulfate
indicated for the management of moderate to severe pain when a continuous, around-the-clock
opioid analgesic is needed for an extended period of time.
Kadian® Capsules are NOT for use as a prn analgesic.

Kadian® 100 mg Capsules ARE FOR USE IN OPIOID-TOLERANT PATIENTS ONLY.
Ingestion of these capsules or of the pellets within the capsules may cause
fatal respiratory depression when administered to patients not already tolerant
to high doses of opioids. KADIAN CAPSULES ARE TO BE SWALLOWED WHOLE
OR THE CONTENTS OF THE CAPSULES SPRINKLED ON APPLE SAUCE. THE PELLETS IN THE
CAPSULES ARE NOT TO BE CHEWED, CRUSHED, OR DISSOLVED DUE TO THE RISK OF RAPID
RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF MORPHINE.

DRUG DESCRIPTION



What are the possible side effects of morphine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to...
Read All Potential Side Effects for Kadian »




Kadian® (morphine sulfate) capsules are an opioid analgesic supplied in
20 mg, 30 mg, 50 mg, 60 mg, 80 mg, and 100 mg strengths for oral administration.

Chemically, morphine sulfate is 7,8-didehydro-4,5 α-
epoxy-17-methyl-morphinan-3,6 α- diol sulfate (2:1)
(salt) pentahydrate and has the following structural formula:








Morphine sulfate is an odorless, white, crystalline powder with
a bitter taste and a molecular weight of 758 (as the sulfate). It has a solubility
of 1 in 21 parts of water and 1 in 1000 parts of alcohol, but is practically
insoluble in chloroform or ether. The octanol: water partition coefficient
of morphine is 1.42 at physiologic pH and the pKb is 7.9 for the
tertiary nitrogen (mostly ionized at pH 7.4).
Each Kadian® extended-release capsule contains either 20 mg, 30 mg, 50
mg, 60 mg, 80 mg, or 100 mg of Morphine Sulfate USP and the following inactive
ingredients common to all strengths: hypromellose, ethylcellulose, methacrylic
acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and
sucrose. The capsule shells contain gelatin, silicon dioxide, sodium lauryl
sulfate, titanium dioxide, and black ink, D&C yellow #10 (20 mg), FD&C
red #3, FD&C blue #1 (30 mg), D&C red #28, FD&C red #40, FD&C
blue #1 (50 mg), D&C red #28, FD&C red #40, FD&C blue #1 (60 mg),
FD&C blue #1, FD&C red #40, FD&C yellow #6 (80 mg), D&C yellow
#10, FD&C blue #1 (100 mg).
Last reviewed on RxList: 1/14/2008




Kadian Drug Description
Kadian
(morphine sulfate) Extended-Release Capsules
CII (Schedule II controlled substance)
Kadian® 20 mg Capsules
Kadian® 30 mg Capsules
Kadian® 50 mg Capsules
Kadian® 60 mg Capsules
Kadian® 80 mg Capsules
Kadian® 100 mg Capsules

WARNING
Kadian® contains morphine sulfate, an opioid agonist and a Schedule II
controlled substance, with an abuse liability similar to other opioid analgesics.
Kadian® can be abused in a manner similar to other opioid agonists, legal
or illicit. This should be considered when prescribing or dispensing Kadian®
in situations where the physician or pharmacist is concerned about an increased
risk of misuse, abuse or diversion.
Kadian® capsules are an extended-release oral formulation of morphine sulfate
indicated for the management of moderate to severe pain when a continuous, around-the-clock
opioid analgesic is needed for an extended period of time.
Kadian® Capsules are NOT for use as a prn analgesic.

Kadian® 100 mg Capsules ARE FOR USE IN OPIOID-TOLERANT PATIENTS ONLY.
Ingestion of these capsules or of the pellets within the capsules may cause
fatal respiratory depression when administered to patients not already tolerant
to high doses of opioids. KADIAN CAPSULES ARE TO BE SWALLOWED WHOLE
OR THE CONTENTS OF THE CAPSULES SPRINKLED ON APPLE SAUCE. THE PELLETS IN THE
CAPSULES ARE NOT TO BE CHEWED, CRUSHED, OR DISSOLVED DUE TO THE RISK OF RAPID
RELEASE AND ABSORPTION OF A POTENTIALLY FATAL DOSE OF MORPHINE.

DRUG DESCRIPTION



What are the possible side effects of morphine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
seizure (convulsions);
cold, clammy skin;
confusion;
severe weakness or dizziness; or
feeling light-headed, fainting.

Less serious side effects are more likely to...
Read All Potential Side Effects for Kadian »




Kadian® (morphine sulfate) capsules are an opioid analgesic supplied in
20 mg, 30 mg, 50 mg, 60 mg, 80 mg, and 100 mg strengths for oral administration.

Chemically, morphine sulfate is 7,8-didehydro-4,5 α-
epoxy-17-methyl-morphinan-3,6 α- diol sulfate (2:1)
(salt) pentahydrate and has the following structural formula:








Morphine sulfate is an odorless, white, crystalline powder with
a bitter taste and a molecular weight of 758 (as the sulfate). It has a solubility
of 1 in 21 parts of water and 1 in 1000 parts of alcohol, but is practically
insoluble in chloroform or ether. The octanol: water partition coefficient
of morphine is 1.42 at physiologic pH and the pKb is 7.9 for the
tertiary nitrogen (mostly ionized at pH 7.4).
Each Kadian® extended-release capsule contains either 20 mg, 30 mg, 50
mg, 60 mg, 80 mg, or 100 mg of Morphine Sulfate USP and the following inactive
ingredients common to all strengths: hypromellose, ethylcellulose, methacrylic
acid copolymer, polyethylene glycol, diethyl phthalate, talc, corn starch, and
sucrose. The capsule shells contain gelatin, silicon dioxide, sodium lauryl
sulfate, titanium dioxide, and black ink, D&C yellow #10 (20 mg), FD&C
red #3, FD&C blue #1 (30 mg), D&C red #28, FD&C red #40, FD&C
blue #1 (50 mg), D&C red #28, FD&C red #40, FD&C blue #1 (60 mg),
FD&C blue #1, FD&C red #40, FD&C yellow #6 (80 mg), D&C yellow
#10, FD&C blue #1 (100 mg).
Last reviewed on RxList: 1/14/2008





Other reviews about Morphine Sulfate Extended-Release on wordpress

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  by swallowed
BETHESDA, MD, 10 June 2008 — A single lot of morphine sulfate has been recalled because some of the tablets may contain twice the labeled level of the […]


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Morphine sulfate extended-release tablets should be used in pregnant women only if the need for strong opioid analgesia clearly outweighs the potential risk to the fetus (see also ... Morphine ER Official FDA information, side effects and uses.


Morphine Sulfate Oral tablet, extended-release To return to the main entry click here . What is this medicine? MORPHINE (MOR feen) is a pain reliever Morphine Sulfate Oral tablet, extended-release: Information from ...


Morphine Sulfate Oral capsule, extended-release To return to the main entry click here . What is this medicine? MORPHINE (MOR feen) is a pain reliever Morphine Sulfate Oral capsule, extended-release: Information from ...


Morphine Sulfate Extended-Release Tabletsis only indicated for postoperative use if the patient is already receiving the drug prior to surgery or if the postoperative pain is ... Morphine Sulfate Official FDA information, side effects and uses.


Learn about the prescription medication Kadian (Morphine Sulfate Extended-Release), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Kadian (Morphine Sulfate Extended-Release) Drug Information: Uses ...


Section Contents Menu. MedWatch The FDA Safety Information and Adverse Event Reporting Program; Safety Information; Safety Alerts for Human Medical Products Morphine Sulfate 60 mg Extended Release Tablets


Morphine Sulfate. 16 April 2008. Products Affected - Description. Morphine sulfate extended-release oral tablets (MS Contin), Purdue Frederick 15 mg tablets, 120/package (NDC 00034-0514 ... Bulletin


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Reason for the Shortage. Morphine sulfate extended-release oral products are FDA approved. Mallinckrodt, Endo, and Xanodyne could not provide a reason for the shortage. Bulletin


Information about treatment of moderate to severe chronic pain with once-daily AVINZA® (morphine sulfate extended-release capsules). AVINZA® Official Home Page





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