Reviews Methylprednisolone Sodium Succinate

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A-Methapred Drug Description
A-METHAPRED
(methylprednisolone sodium succinate) Injection, Powder, Lyophilized, for Solution

For Intravenous or Intramuscular Administration
DRUG DESCRIPTION
A-Methapred (methylprednisolone sodium succinate for injection, USP) sterile
powder contains methylprednisolone sodium succinate as the active ingredient.
Methylprednisolone sodium succinate, USP, occurs as a white, or nearly white,
odorless hygroscopic, amorphous solid. It is very soluble in water and in alcohol;
it is insoluble in chloroform and is very slightly soluble in acetone.
The chemical name for methylprednisolone sodium succinate is pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxo-propoxy)-11,17-dihydroxy-6-methyl-monosodium
salt, (6a, 11ß), and the molecular weight is 496.53.
The structural formula is represented below:







Methylprednisolone sodium succinate is so extremely soluble in water that
it may be administered in a small volume of diluent and is especially well suited
for intravenous use in situations in which high blood levels of methylprednisolone
are required rapidly.
A-Methapred is available in several strengths and packages for intravenous
or intramuscular administration.
40 mg Single-Dose Vial- Each mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 40 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.46 mg dibasic sodium phosphate anhydrous; 25
mg lactose anhydrous; 8.8 mg benzyl alcohol added as preservative.
125 mg Single-Dose Vial- Each 2 mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 125 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.4 mg dibasic sodium phosphate anhydrous; 17.6
mg benzyl alcohol added as preservative.
When necessary, the pH of each formula was adjusted with sodium hydroxide
so that the pH of the reconstituted solution is within the USP specified range
of 7 to 8 and the tonicities are, for the 40 mg per mL solution, 0.50 osmolar;
for the 125 mg per 2 mL, 0.40 osmolar; (Isotonic saline = 0.28 osmolar).
IMPORTANT- Use only Bacteriostatic Water For Injection with Benzyl Alcohol
when reconstituting A-Methapred.
Use within 48 hours after mixing. Last reviewed on RxList: 2/13/2009




A-Methapred Drug Description
A-METHAPRED
(methylprednisolone sodium succinate) Injection, Powder, Lyophilized, for Solution

For Intravenous or Intramuscular Administration
DRUG DESCRIPTION
A-Methapred (methylprednisolone sodium succinate for injection, USP) sterile
powder contains methylprednisolone sodium succinate as the active ingredient.
Methylprednisolone sodium succinate, USP, occurs as a white, or nearly white,
odorless hygroscopic, amorphous solid. It is very soluble in water and in alcohol;
it is insoluble in chloroform and is very slightly soluble in acetone.
The chemical name for methylprednisolone sodium succinate is pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxo-propoxy)-11,17-dihydroxy-6-methyl-monosodium
salt, (6a, 11ß), and the molecular weight is 496.53.
The structural formula is represented below:







Methylprednisolone sodium succinate is so extremely soluble in water that
it may be administered in a small volume of diluent and is especially well suited
for intravenous use in situations in which high blood levels of methylprednisolone
are required rapidly.
A-Methapred is available in several strengths and packages for intravenous
or intramuscular administration.
40 mg Single-Dose Vial- Each mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 40 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.46 mg dibasic sodium phosphate anhydrous; 25
mg lactose anhydrous; 8.8 mg benzyl alcohol added as preservative.
125 mg Single-Dose Vial- Each 2 mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 125 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.4 mg dibasic sodium phosphate anhydrous; 17.6
mg benzyl alcohol added as preservative.
When necessary, the pH of each formula was adjusted with sodium hydroxide
so that the pH of the reconstituted solution is within the USP specified range
of 7 to 8 and the tonicities are, for the 40 mg per mL solution, 0.50 osmolar;
for the 125 mg per 2 mL, 0.40 osmolar; (Isotonic saline = 0.28 osmolar).
IMPORTANT- Use only Bacteriostatic Water For Injection with Benzyl Alcohol
when reconstituting A-Methapred.
Use within 48 hours after mixing. Last reviewed on RxList: 2/13/2009




A-Methapred Drug Description
A-METHAPRED
(methylprednisolone sodium succinate) Injection, Powder, Lyophilized, for Solution

For Intravenous or Intramuscular Administration
DRUG DESCRIPTION
A-Methapred (methylprednisolone sodium succinate for injection, USP) sterile
powder contains methylprednisolone sodium succinate as the active ingredient.
Methylprednisolone sodium succinate, USP, occurs as a white, or nearly white,
odorless hygroscopic, amorphous solid. It is very soluble in water and in alcohol;
it is insoluble in chloroform and is very slightly soluble in acetone.
The chemical name for methylprednisolone sodium succinate is pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxo-propoxy)-11,17-dihydroxy-6-methyl-monosodium
salt, (6a, 11ß), and the molecular weight is 496.53.
The structural formula is represented below:







Methylprednisolone sodium succinate is so extremely soluble in water that
it may be administered in a small volume of diluent and is especially well suited
for intravenous use in situations in which high blood levels of methylprednisolone
are required rapidly.
A-Methapred is available in several strengths and packages for intravenous
or intramuscular administration.
40 mg Single-Dose Vial- Each mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 40 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.46 mg dibasic sodium phosphate anhydrous; 25
mg lactose anhydrous; 8.8 mg benzyl alcohol added as preservative.
125 mg Single-Dose Vial- Each 2 mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 125 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.4 mg dibasic sodium phosphate anhydrous; 17.6
mg benzyl alcohol added as preservative.
When necessary, the pH of each formula was adjusted with sodium hydroxide
so that the pH of the reconstituted solution is within the USP specified range
of 7 to 8 and the tonicities are, for the 40 mg per mL solution, 0.50 osmolar;
for the 125 mg per 2 mL, 0.40 osmolar; (Isotonic saline = 0.28 osmolar).
IMPORTANT- Use only Bacteriostatic Water For Injection with Benzyl Alcohol
when reconstituting A-Methapred.
Use within 48 hours after mixing. Last reviewed on RxList: 2/13/2009




A-Methapred Drug Description
A-METHAPRED
(methylprednisolone sodium succinate) Injection, Powder, Lyophilized, for Solution

For Intravenous or Intramuscular Administration
DRUG DESCRIPTION
A-Methapred (methylprednisolone sodium succinate for injection, USP) sterile
powder contains methylprednisolone sodium succinate as the active ingredient.
Methylprednisolone sodium succinate, USP, occurs as a white, or nearly white,
odorless hygroscopic, amorphous solid. It is very soluble in water and in alcohol;
it is insoluble in chloroform and is very slightly soluble in acetone.
The chemical name for methylprednisolone sodium succinate is pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxo-propoxy)-11,17-dihydroxy-6-methyl-monosodium
salt, (6a, 11ß), and the molecular weight is 496.53.
The structural formula is represented below:







Methylprednisolone sodium succinate is so extremely soluble in water that
it may be administered in a small volume of diluent and is especially well suited
for intravenous use in situations in which high blood levels of methylprednisolone
are required rapidly.
A-Methapred is available in several strengths and packages for intravenous
or intramuscular administration.
40 mg Single-Dose Vial- Each mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 40 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.46 mg dibasic sodium phosphate anhydrous; 25
mg lactose anhydrous; 8.8 mg benzyl alcohol added as preservative.
125 mg Single-Dose Vial- Each 2 mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 125 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.4 mg dibasic sodium phosphate anhydrous; 17.6
mg benzyl alcohol added as preservative.
When necessary, the pH of each formula was adjusted with sodium hydroxide
so that the pH of the reconstituted solution is within the USP specified range
of 7 to 8 and the tonicities are, for the 40 mg per mL solution, 0.50 osmolar;
for the 125 mg per 2 mL, 0.40 osmolar; (Isotonic saline = 0.28 osmolar).
IMPORTANT- Use only Bacteriostatic Water For Injection with Benzyl Alcohol
when reconstituting A-Methapred.
Use within 48 hours after mixing. Last reviewed on RxList: 2/13/2009




A-Methapred Drug Description
A-METHAPRED
(methylprednisolone sodium succinate) Injection, Powder, Lyophilized, for Solution

For Intravenous or Intramuscular Administration
DRUG DESCRIPTION
A-Methapred (methylprednisolone sodium succinate for injection, USP) sterile
powder contains methylprednisolone sodium succinate as the active ingredient.
Methylprednisolone sodium succinate, USP, occurs as a white, or nearly white,
odorless hygroscopic, amorphous solid. It is very soluble in water and in alcohol;
it is insoluble in chloroform and is very slightly soluble in acetone.
The chemical name for methylprednisolone sodium succinate is pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxo-propoxy)-11,17-dihydroxy-6-methyl-monosodium
salt, (6a, 11ß), and the molecular weight is 496.53.
The structural formula is represented below:







Methylprednisolone sodium succinate is so extremely soluble in water that
it may be administered in a small volume of diluent and is especially well suited
for intravenous use in situations in which high blood levels of methylprednisolone
are required rapidly.
A-Methapred is available in several strengths and packages for intravenous
or intramuscular administration.
40 mg Single-Dose Vial- Each mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 40 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.46 mg dibasic sodium phosphate anhydrous; 25
mg lactose anhydrous; 8.8 mg benzyl alcohol added as preservative.
125 mg Single-Dose Vial- Each 2 mL (when mixed) contains methylprednisolone
sodium succinate equivalent to 125 mg methylprednisolone; also 1.6 mg monobasic
sodium phosphate anhydrous; 17.4 mg dibasic sodium phosphate anhydrous; 17.6
mg benzyl alcohol added as preservative.
When necessary, the pH of each formula was adjusted with sodium hydroxide
so that the pH of the reconstituted solution is within the USP specified range
of 7 to 8 and the tonicities are, for the 40 mg per mL solution, 0.50 osmolar;
for the 125 mg per 2 mL, 0.40 osmolar; (Isotonic saline = 0.28 osmolar).
IMPORTANT- Use only Bacteriostatic Water For Injection with Benzyl Alcohol
when reconstituting A-Methapred.
Use within 48 hours after mixing. Last reviewed on RxList: 2/13/2009





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Other reviews about Methylprednisolone Sodium Succinate on web:

Your doctor has ordered methylprednisolone, a corticosteroid, to relieve inflammation (swelling, heat, redness, and pain). The drug will be added to an intravenous fluid that will ... Methylprednisolone Sodium Succinate Injection: MedlinePlus Drug ...


Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug. It is sold in the USA and Canada under the brand names Medrol, Solu-Medrol and Cadista. It is also available ... Methylprednisolone - Wikipedia, the free encyclopedia


Learn about the prescription medication Solu Medrol (Methylprednisolone sodium succinate), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling. Solu Medrol (Methylprednisolone sodium succinate) Drug Information ...


Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. methylprednisolone sodium succinate - definition of ...


Methylprednisolone sodium succinate, Solu-Medrol, Pfizer 40 mg vials (NDC 00009-0113-19) – discontinued 125 mg vials (NDC 00009-0190-16) – discontinued Bulletin


Methylprednisolone Sodium Succinate Solution for injection To return to the main entry click here . What is this medicine? METHYLPREDNISOLONE (meth Methylprednisolone Sodium Succinate Solution for injection ...


Accurate, FDA approved Methylprednisolone Sodium Succinate Injection information for healthcare professionals and patients - brought to you by Drugs.com. Methylprednisolone Sodium Succinate Injection Official FDA ...


1 SOLU-MEDROL ® methylprednisolone sodium succinate for injection, USP For Intravenous or Intramuscular Administration DESCRIPTION SOLU-MEDROL Sterile Powder contains ... SOLU-MEDROL® methylprednisolone sodium succinate for injection, USP


A-METHAPRED SUMMARY A-METHAPRED ® Methylprednisolone Sodium Succinate for Injection, USP. Methylprednisolone Sodium Succinate, USP, an adrenocortical-like steroid, is the sodium ... A-Methapred (Methylprednisolone) - Drug Info, Side Effects ...


Methylprednisolone belongs to a group of medicines known as corticosteroids. Corticosteroids, such as cortisol, are hormones that are produced naturally in our body, and ... Methylprednisolone sodium succinate (by Hospira) - Uses, Side ...





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