Reviews Metformin Hcl


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Fortamet Drug Description
FORTAMET®
(metformin hydrochloride) Extended-Release Tablets
DRUG DESCRIPTION



What are the possible side effects of metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)?

Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Stop using metformin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of...
Read All Potential Side Effects for Fortamet »




FORTAMET® (metformin hydrochloride) Extended-Release Tablets contain an
oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin
hydrochloride (N, N­ dimethylimidodicarbonimidic diamide hydrochloride) is a
member of the biguanide class of oral antihyperglycemics and is not chemically
or pharmacologically related to any other class of oral antihyperglycemic agents.
The empirical formula of metformin hydrochloride is C4H11N5•HCl
and its molecular weight is 165.63. Its structural formula is:







Metformin hydrochloride is a white to off-white crystalline powder that is
freely soluble in water and is practically insoluble in acetone, ether, and
chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of
metformin hydrochloride is 6.68.
FORTAMET® Extended-Release Tablets are designed for once-a-day oral administration
and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the
active ingredient metformin hydrochloride, each tablet contains the following
inactive ingredients: candellila wax, cellulose acetate, hypromellose, magnesium
stearate, polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone,
sodium lauryl sulfate, synthetic black iron oxides, titanium dioxide, and triacetin.
FORTAMET® meets USP Dissolution Test 5.
System Components And performance
FORTAMET® was developed as an extended-release formulation of metformin hydrochloride and designed for once-a-day oral administration using the patented single-composition osmotic technology (SCOT™). The tablet is similar in appearance to other film-coated oral administered tablets but it consists of an osmotically active core formulation that is surrounded by a semipermeable membrane. Two laser drilled exit ports exist in the membrane, one on either side of the tablet. The core formulation is composed primarily of drug with small concentrations of excipients. The semipermeable membrane is permeable to water but not to higher molecular weight components of biological fluids. Upon ingestion, water is taken up through the membrane, which in turn dissolves the drug and excipients in the core formulation. The dissolved drug and excipients exit through the laser drilled ports in the membrane. The rate of drug delivery is constant and dependent upon the maintenance of a constant osmotic gradient across the membrane. This situation exists so long as there is undissolved drug present in the core tablet. Following the dissolution of the core materials, the rate of drug delivery slowly decreases until the osmotic gradient across the membrane falls to zero at which time delivery ceases. The membrane coating remains intact during the transit of the dosage form through the gastrointestinal tract and is excreted in the feces.
Last reviewed on RxList: 9/25/2008




Fortamet Drug Description
FORTAMET®
(metformin hydrochloride) Extended-Release Tablets
DRUG DESCRIPTION



What are the possible side effects of metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)?

Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Stop using metformin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of...
Read All Potential Side Effects for Fortamet »




FORTAMET® (metformin hydrochloride) Extended-Release Tablets contain an
oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin
hydrochloride (N, N­ dimethylimidodicarbonimidic diamide hydrochloride) is a
member of the biguanide class of oral antihyperglycemics and is not chemically
or pharmacologically related to any other class of oral antihyperglycemic agents.
The empirical formula of metformin hydrochloride is C4H11N5•HCl
and its molecular weight is 165.63. Its structural formula is:







Metformin hydrochloride is a white to off-white crystalline powder that is
freely soluble in water and is practically insoluble in acetone, ether, and
chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of
metformin hydrochloride is 6.68.
FORTAMET® Extended-Release Tablets are designed for once-a-day oral administration
and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the
active ingredient metformin hydrochloride, each tablet contains the following
inactive ingredients: candellila wax, cellulose acetate, hypromellose, magnesium
stearate, polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone,
sodium lauryl sulfate, synthetic black iron oxides, titanium dioxide, and triacetin.
FORTAMET® meets USP Dissolution Test 5.
System Components And performance
FORTAMET® was developed as an extended-release formulation of metformin hydrochloride and designed for once-a-day oral administration using the patented single-composition osmotic technology (SCOT™). The tablet is similar in appearance to other film-coated oral administered tablets but it consists of an osmotically active core formulation that is surrounded by a semipermeable membrane. Two laser drilled exit ports exist in the membrane, one on either side of the tablet. The core formulation is composed primarily of drug with small concentrations of excipients. The semipermeable membrane is permeable to water but not to higher molecular weight components of biological fluids. Upon ingestion, water is taken up through the membrane, which in turn dissolves the drug and excipients in the core formulation. The dissolved drug and excipients exit through the laser drilled ports in the membrane. The rate of drug delivery is constant and dependent upon the maintenance of a constant osmotic gradient across the membrane. This situation exists so long as there is undissolved drug present in the core tablet. Following the dissolution of the core materials, the rate of drug delivery slowly decreases until the osmotic gradient across the membrane falls to zero at which time delivery ceases. The membrane coating remains intact during the transit of the dosage form through the gastrointestinal tract and is excreted in the feces.
Last reviewed on RxList: 9/25/2008




Fortamet Drug Description
FORTAMET®
(metformin hydrochloride) Extended-Release Tablets
DRUG DESCRIPTION



What are the possible side effects of metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)?

Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Stop using metformin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of...
Read All Potential Side Effects for Fortamet »




FORTAMET® (metformin hydrochloride) Extended-Release Tablets contain an
oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin
hydrochloride (N, N­ dimethylimidodicarbonimidic diamide hydrochloride) is a
member of the biguanide class of oral antihyperglycemics and is not chemically
or pharmacologically related to any other class of oral antihyperglycemic agents.
The empirical formula of metformin hydrochloride is C4H11N5•HCl
and its molecular weight is 165.63. Its structural formula is:







Metformin hydrochloride is a white to off-white crystalline powder that is
freely soluble in water and is practically insoluble in acetone, ether, and
chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of
metformin hydrochloride is 6.68.
FORTAMET® Extended-Release Tablets are designed for once-a-day oral administration
and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the
active ingredient metformin hydrochloride, each tablet contains the following
inactive ingredients: candellila wax, cellulose acetate, hypromellose, magnesium
stearate, polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone,
sodium lauryl sulfate, synthetic black iron oxides, titanium dioxide, and triacetin.
FORTAMET® meets USP Dissolution Test 5.
System Components And performance
FORTAMET® was developed as an extended-release formulation of metformin hydrochloride and designed for once-a-day oral administration using the patented single-composition osmotic technology (SCOT™). The tablet is similar in appearance to other film-coated oral administered tablets but it consists of an osmotically active core formulation that is surrounded by a semipermeable membrane. Two laser drilled exit ports exist in the membrane, one on either side of the tablet. The core formulation is composed primarily of drug with small concentrations of excipients. The semipermeable membrane is permeable to water but not to higher molecular weight components of biological fluids. Upon ingestion, water is taken up through the membrane, which in turn dissolves the drug and excipients in the core formulation. The dissolved drug and excipients exit through the laser drilled ports in the membrane. The rate of drug delivery is constant and dependent upon the maintenance of a constant osmotic gradient across the membrane. This situation exists so long as there is undissolved drug present in the core tablet. Following the dissolution of the core materials, the rate of drug delivery slowly decreases until the osmotic gradient across the membrane falls to zero at which time delivery ceases. The membrane coating remains intact during the transit of the dosage form through the gastrointestinal tract and is excreted in the feces.
Last reviewed on RxList: 9/25/2008




Fortamet Drug Description
FORTAMET®
(metformin hydrochloride) Extended-Release Tablets
DRUG DESCRIPTION



What are the possible side effects of metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)?

Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Stop using metformin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of...
Read All Potential Side Effects for Fortamet »




FORTAMET® (metformin hydrochloride) Extended-Release Tablets contain an
oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin
hydrochloride (N, N­ dimethylimidodicarbonimidic diamide hydrochloride) is a
member of the biguanide class of oral antihyperglycemics and is not chemically
or pharmacologically related to any other class of oral antihyperglycemic agents.
The empirical formula of metformin hydrochloride is C4H11N5•HCl
and its molecular weight is 165.63. Its structural formula is:







Metformin hydrochloride is a white to off-white crystalline powder that is
freely soluble in water and is practically insoluble in acetone, ether, and
chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of
metformin hydrochloride is 6.68.
FORTAMET® Extended-Release Tablets are designed for once-a-day oral administration
and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the
active ingredient metformin hydrochloride, each tablet contains the following
inactive ingredients: candellila wax, cellulose acetate, hypromellose, magnesium
stearate, polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone,
sodium lauryl sulfate, synthetic black iron oxides, titanium dioxide, and triacetin.
FORTAMET® meets USP Dissolution Test 5.
System Components And performance
FORTAMET® was developed as an extended-release formulation of metformin hydrochloride and designed for once-a-day oral administration using the patented single-composition osmotic technology (SCOT™). The tablet is similar in appearance to other film-coated oral administered tablets but it consists of an osmotically active core formulation that is surrounded by a semipermeable membrane. Two laser drilled exit ports exist in the membrane, one on either side of the tablet. The core formulation is composed primarily of drug with small concentrations of excipients. The semipermeable membrane is permeable to water but not to higher molecular weight components of biological fluids. Upon ingestion, water is taken up through the membrane, which in turn dissolves the drug and excipients in the core formulation. The dissolved drug and excipients exit through the laser drilled ports in the membrane. The rate of drug delivery is constant and dependent upon the maintenance of a constant osmotic gradient across the membrane. This situation exists so long as there is undissolved drug present in the core tablet. Following the dissolution of the core materials, the rate of drug delivery slowly decreases until the osmotic gradient across the membrane falls to zero at which time delivery ceases. The membrane coating remains intact during the transit of the dosage form through the gastrointestinal tract and is excreted in the feces.
Last reviewed on RxList: 9/25/2008




Fortamet Drug Description
FORTAMET®
(metformin hydrochloride) Extended-Release Tablets
DRUG DESCRIPTION



What are the possible side effects of metformin (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)?

Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Stop using metformin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of...
Read All Potential Side Effects for Fortamet »




FORTAMET® (metformin hydrochloride) Extended-Release Tablets contain an
oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin
hydrochloride (N, N­ dimethylimidodicarbonimidic diamide hydrochloride) is a
member of the biguanide class of oral antihyperglycemics and is not chemically
or pharmacologically related to any other class of oral antihyperglycemic agents.
The empirical formula of metformin hydrochloride is C4H11N5•HCl
and its molecular weight is 165.63. Its structural formula is:







Metformin hydrochloride is a white to off-white crystalline powder that is
freely soluble in water and is practically insoluble in acetone, ether, and
chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of
metformin hydrochloride is 6.68.
FORTAMET® Extended-Release Tablets are designed for once-a-day oral administration
and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the
active ingredient metformin hydrochloride, each tablet contains the following
inactive ingredients: candellila wax, cellulose acetate, hypromellose, magnesium
stearate, polyethylene glycols (PEG 400, PEG 8000), polysorbate 80, povidone,
sodium lauryl sulfate, synthetic black iron oxides, titanium dioxide, and triacetin.
FORTAMET® meets USP Dissolution Test 5.
System Components And performance
FORTAMET® was developed as an extended-release formulation of metformin hydrochloride and designed for once-a-day oral administration using the patented single-composition osmotic technology (SCOT™). The tablet is similar in appearance to other film-coated oral administered tablets but it consists of an osmotically active core formulation that is surrounded by a semipermeable membrane. Two laser drilled exit ports exist in the membrane, one on either side of the tablet. The core formulation is composed primarily of drug with small concentrations of excipients. The semipermeable membrane is permeable to water but not to higher molecular weight components of biological fluids. Upon ingestion, water is taken up through the membrane, which in turn dissolves the drug and excipients in the core formulation. The dissolved drug and excipients exit through the laser drilled ports in the membrane. The rate of drug delivery is constant and dependent upon the maintenance of a constant osmotic gradient across the membrane. This situation exists so long as there is undissolved drug present in the core tablet. Following the dissolution of the core materials, the rate of drug delivery slowly decreases until the osmotic gradient across the membrane falls to zero at which time delivery ceases. The membrane coating remains intact during the transit of the dosage form through the gastrointestinal tract and is excreted in the feces.
Last reviewed on RxList: 9/25/2008





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Other reviews about Metformin Hcl on web:

Learn about the prescription medication Glucophage, Glucophage XR (Metformin Hcl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Glucophage, Glucophage XR (Metformin Hcl) Drug Information: Uses ...


Metformin HCl is a prescription medicine licensed to treat diabetes. This article on the eMedTV site describes the effects of metformin and explains what different forms this ... Metformin HCL


Metformin (pronounced /mɛtˈfɔrmɪn/; originally sold as Glucophage) is an oral anti-diabetic drug in the biguanide class. It is the first-line drug of choice for the treatment of ... Metformin - Wikipedia, the free encyclopedia


Metformin information from Drugs.com, includes Metformin side effects, interactions and indications. Metformin Information from Drugs.com


MetFORMIN HCl is a biguanide antidiabetic used along with a diet and exercise program to control high blood sugar in patients with type 2 diabetes. Side effects and ... Metformin Hcl - drugstore.com. Low prices, side effects, interactions.


Learn about the prescription medication Riomet (Metformin Hcl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Riomet (Metformin Hcl) Drug Information: Uses, Side Effects, Drug ...


Glipizide/Metformin HCl professional patient advice. Specific and up to date information about Glipizide/Metformin HCl. Complete Glipizide/Metformin HCl information from Drugs.com


What Is Metformin HCL?. Metformin hydrochloride or HCL is a generic prescription oral medication available in liquid or capsule form. Doctors typically prescribe metformin HCL for ... What Is Metformin HCL? | eHow.com


Member since: April 17, 2006 Total points: 69306 (Level 7) Badge Image: Contributing In: Software Diabetes Printers Other - Hardware. Add to My Contacts What is metformin hcl er? - Yahoo! Answers


PCOS and Metformin (Glucophage) Metformin (brand name ... Metformin is available in three different forms: Generic Metformin Hcl Metformin for PCOS: Discover the Benefits and Side Effects of ...





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