Reviews Lopinavir, Ritonavir Tablets


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Kaletra Tablets Drug Description
KALETRA
(lopinavir and ritonavir) Tablet, Film Coated
KALETRA
(lopinavir and ritonavir) Solution
DRUG DESCRIPTION



What are the possible side effects of lopinavir and ritonavir (Kaletra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ritonavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as...
Read All Potential Side Effects for Kaletra Tablets »




KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir.
Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA,
ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing
increased plasma levels of lopinavir.
Lopinavir is chemically designated as [1S-[1R*,(R*), 3R*, 4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide.
Its molecular formula is C37H48N4O5,
and its molecular weight is 628.80. Lopinavir is a white to light tan powder.
It is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Lopinavir has the following structural formula:








Ritonavir is chemically designated as 10-hydroxy-2-methyl-5-(1-methylethyl)-1-
[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula
is C37H48N6O5S2, and
its molecular weight is 720.95. Ritonavir is a white to light tan powder. It
is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Ritonavir has the following structural formula:








KALETRA film-coated tablets are available for oral administration in two strengths:

Yellow tablets containing 200 mg of lopinavir and 50 mg of ritonavir
Pale yellow tablets containing 100 mg of lopinavir and 25 mg of ritonavir.

The yellow, 200 mg lopinavir/50 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose,
talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide
E172, and polysorbate 80.
The pale yellow, 100 mg lopinavir/25 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, and yellow
ferric oxide E172.
KALETRA oral solution is available for oral administration as 80 mg lopinavir
and 20 mg ritonavir per milliliter with the following inactive ingredients:
acesulfame potassium, alcohol, artificial cotton candy flavor, citric acid,
glycerin, high fructose corn syrup, Magnasweet-110 flavor, menthol, natural
& artificial vanilla flavor, peppermint oil, polyoxyl 40 hydrogenated castor
oil, povidone, propylene glycol, saccharin sodium, sodium chloride, sodium citrate,
and water.
KALETRA oral solution contains 42.4% alcohol (v/v).
Last reviewed on RxList: 7/13/2010




Kaletra Tablets Drug Description
KALETRA
(lopinavir and ritonavir) Tablet, Film Coated
KALETRA
(lopinavir and ritonavir) Solution
DRUG DESCRIPTION



What are the possible side effects of lopinavir and ritonavir (Kaletra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ritonavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as...
Read All Potential Side Effects for Kaletra Tablets »




KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir.
Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA,
ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing
increased plasma levels of lopinavir.
Lopinavir is chemically designated as [1S-[1R*,(R*), 3R*, 4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide.
Its molecular formula is C37H48N4O5,
and its molecular weight is 628.80. Lopinavir is a white to light tan powder.
It is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Lopinavir has the following structural formula:








Ritonavir is chemically designated as 10-hydroxy-2-methyl-5-(1-methylethyl)-1-
[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula
is C37H48N6O5S2, and
its molecular weight is 720.95. Ritonavir is a white to light tan powder. It
is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Ritonavir has the following structural formula:








KALETRA film-coated tablets are available for oral administration in two strengths:

Yellow tablets containing 200 mg of lopinavir and 50 mg of ritonavir
Pale yellow tablets containing 100 mg of lopinavir and 25 mg of ritonavir.

The yellow, 200 mg lopinavir/50 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose,
talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide
E172, and polysorbate 80.
The pale yellow, 100 mg lopinavir/25 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, and yellow
ferric oxide E172.
KALETRA oral solution is available for oral administration as 80 mg lopinavir
and 20 mg ritonavir per milliliter with the following inactive ingredients:
acesulfame potassium, alcohol, artificial cotton candy flavor, citric acid,
glycerin, high fructose corn syrup, Magnasweet-110 flavor, menthol, natural
& artificial vanilla flavor, peppermint oil, polyoxyl 40 hydrogenated castor
oil, povidone, propylene glycol, saccharin sodium, sodium chloride, sodium citrate,
and water.
KALETRA oral solution contains 42.4% alcohol (v/v).
Last reviewed on RxList: 7/13/2010




Kaletra Tablets Drug Description
KALETRA
(lopinavir and ritonavir) Tablet, Film Coated
KALETRA
(lopinavir and ritonavir) Solution
DRUG DESCRIPTION



What are the possible side effects of lopinavir and ritonavir (Kaletra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ritonavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as...
Read All Potential Side Effects for Kaletra Tablets »




KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir.
Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA,
ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing
increased plasma levels of lopinavir.
Lopinavir is chemically designated as [1S-[1R*,(R*), 3R*, 4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide.
Its molecular formula is C37H48N4O5,
and its molecular weight is 628.80. Lopinavir is a white to light tan powder.
It is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Lopinavir has the following structural formula:








Ritonavir is chemically designated as 10-hydroxy-2-methyl-5-(1-methylethyl)-1-
[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula
is C37H48N6O5S2, and
its molecular weight is 720.95. Ritonavir is a white to light tan powder. It
is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Ritonavir has the following structural formula:








KALETRA film-coated tablets are available for oral administration in two strengths:

Yellow tablets containing 200 mg of lopinavir and 50 mg of ritonavir
Pale yellow tablets containing 100 mg of lopinavir and 25 mg of ritonavir.

The yellow, 200 mg lopinavir/50 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose,
talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide
E172, and polysorbate 80.
The pale yellow, 100 mg lopinavir/25 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, and yellow
ferric oxide E172.
KALETRA oral solution is available for oral administration as 80 mg lopinavir
and 20 mg ritonavir per milliliter with the following inactive ingredients:
acesulfame potassium, alcohol, artificial cotton candy flavor, citric acid,
glycerin, high fructose corn syrup, Magnasweet-110 flavor, menthol, natural
& artificial vanilla flavor, peppermint oil, polyoxyl 40 hydrogenated castor
oil, povidone, propylene glycol, saccharin sodium, sodium chloride, sodium citrate,
and water.
KALETRA oral solution contains 42.4% alcohol (v/v).
Last reviewed on RxList: 7/13/2010




Kaletra Tablets Drug Description
KALETRA
(lopinavir and ritonavir) Tablet, Film Coated
KALETRA
(lopinavir and ritonavir) Solution
DRUG DESCRIPTION



What are the possible side effects of lopinavir and ritonavir (Kaletra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ritonavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as...
Read All Potential Side Effects for Kaletra Tablets »




KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir.
Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA,
ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing
increased plasma levels of lopinavir.
Lopinavir is chemically designated as [1S-[1R*,(R*), 3R*, 4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide.
Its molecular formula is C37H48N4O5,
and its molecular weight is 628.80. Lopinavir is a white to light tan powder.
It is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Lopinavir has the following structural formula:








Ritonavir is chemically designated as 10-hydroxy-2-methyl-5-(1-methylethyl)-1-
[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula
is C37H48N6O5S2, and
its molecular weight is 720.95. Ritonavir is a white to light tan powder. It
is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Ritonavir has the following structural formula:








KALETRA film-coated tablets are available for oral administration in two strengths:

Yellow tablets containing 200 mg of lopinavir and 50 mg of ritonavir
Pale yellow tablets containing 100 mg of lopinavir and 25 mg of ritonavir.

The yellow, 200 mg lopinavir/50 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose,
talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide
E172, and polysorbate 80.
The pale yellow, 100 mg lopinavir/25 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, and yellow
ferric oxide E172.
KALETRA oral solution is available for oral administration as 80 mg lopinavir
and 20 mg ritonavir per milliliter with the following inactive ingredients:
acesulfame potassium, alcohol, artificial cotton candy flavor, citric acid,
glycerin, high fructose corn syrup, Magnasweet-110 flavor, menthol, natural
& artificial vanilla flavor, peppermint oil, polyoxyl 40 hydrogenated castor
oil, povidone, propylene glycol, saccharin sodium, sodium chloride, sodium citrate,
and water.
KALETRA oral solution contains 42.4% alcohol (v/v).
Last reviewed on RxList: 7/13/2010




Kaletra Tablets Drug Description
KALETRA
(lopinavir and ritonavir) Tablet, Film Coated
KALETRA
(lopinavir and ritonavir) Solution
DRUG DESCRIPTION



What are the possible side effects of lopinavir and ritonavir (Kaletra)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking ritonavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as...
Read All Potential Side Effects for Kaletra Tablets »




KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir.
Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA,
ritonavir inhibits the CYP3A-mediated metabolism of lopinavir, thereby providing
increased plasma levels of lopinavir.
Lopinavir is chemically designated as [1S-[1R*,(R*), 3R*, 4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide.
Its molecular formula is C37H48N4O5,
and its molecular weight is 628.80. Lopinavir is a white to light tan powder.
It is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Lopinavir has the following structural formula:








Ritonavir is chemically designated as 10-hydroxy-2-methyl-5-(1-methylethyl)-1-
[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic
acid, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula
is C37H48N6O5S2, and
its molecular weight is 720.95. Ritonavir is a white to light tan powder. It
is freely soluble in methanol and ethanol, soluble in isopropanol and practically
insoluble in water. Ritonavir has the following structural formula:








KALETRA film-coated tablets are available for oral administration in two strengths:

Yellow tablets containing 200 mg of lopinavir and 50 mg of ritonavir
Pale yellow tablets containing 100 mg of lopinavir and 25 mg of ritonavir.

The yellow, 200 mg lopinavir/50 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose,
talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide
E172, and polysorbate 80.
The pale yellow, 100 mg lopinavir/25 mg ritonavir, tablets contain the following
inactive ingredients: copovidone, sorbitan monolaurate, colloidal silicon dioxide,
and sodium stearyl fumarate. The following are the ingredients in the film coating:
polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, and yellow
ferric oxide E172.
KALETRA oral solution is available for oral administration as 80 mg lopinavir
and 20 mg ritonavir per milliliter with the following inactive ingredients:
acesulfame potassium, alcohol, artificial cotton candy flavor, citric acid,
glycerin, high fructose corn syrup, Magnasweet-110 flavor, menthol, natural
& artificial vanilla flavor, peppermint oil, polyoxyl 40 hydrogenated castor
oil, povidone, propylene glycol, saccharin sodium, sodium chloride, sodium citrate,
and water.
KALETRA oral solution contains 42.4% alcohol (v/v).
Last reviewed on RxList: 7/13/2010





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Other reviews about Lopinavir, Ritonavir Tablets on web:

Lopinavir; Ritonavir tablets To return to the main entry click here . What are lopinavir; ritonavir tablets? LOPINAVIR; RITONAVIR is an antiretroviral Lopinavir; Ritonavir tablets: Information from Answers.com


Lopinavir/ritonavir was approved by the US FDA on 15 September 2000, and in Europe in April ... Abbott: Kaletra (lopinavir/ritonavir) tablets; Lopinavir Product Insert and Packaging ... Lopinavir - Wikipedia, the free encyclopedia


Learn about the prescription medication Kaletra Tablets (Lopinavir, Ritonavir Tablets), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Kaletra Tablets (Lopinavir, Ritonavir Tablets) Drug Information ...


Subsequent follow-up of a noncontrolled study showed that viral load suppression with this lopinavir/ritonavir combination persists through 4 years. A tablet formulation of ... Lopinavir/Ritonavir (Kaletra, Aluvia)


No dosing adjustment in treatment-naive patients is necessary when lopinavir/ritonavir tablets are administered as part of a twice-daily regimen with efavirenz, nevirapine ... AIDSinfo - HIV/AIDS Drug Information - Lopinavir/ritonavir


Accessed 12/20/07. Abbott Laboratories Press Release: Abbott Receives U.S. Food and Drug Administration Approval for New Lower-Strength Kaletra (lopinavir/ritonavir) Tablet for ... AIDSinfo - HIV/AIDS Drug Information - Lopinavir/ritonavir


036-395109 KALETRA ® (lopinavir/ritonavir) tablets (lopinavir/ritonavir) oral solution only HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information ... KALETRA® (lopinavir/ritonavir) tablets (lopinavir/ritonavir) oral ...


Lopinavir; Ritonavir Brand names: Kaletra® Chemical formula: Drug Forms: Lopinavir; Ritonavir tablets (below) Lopinavir, Ritonavir Oral capsule Lopinavir: Information from Answers.com


If you are taking lopinavir and ritonavir tablets, you may take them on an empty stomach at the same time as you take didanosine. tell your doctor what herbal products you are ... Lopinavir and Ritonavir: MedlinePlus Drug Information


All about Lopinavir/Ritonavir Tablets. View complete and up to date Lopinavir/Ritonavir information - part of the Drugs.com trusted medication database. Lopinavir/Ritonavir Tablets Facts and Comparisons at Drugs.com





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