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Invirase Drug Description
INVIRASE®
(saquinavir mesylate) Capsules and Tablets
Product identification in this document includes: INVIRASE in reference
to saquinavir mesylate; saquinavir soft gel capsules in reference to saquinavir
200 mg soft gel capsule formulation1, and saquinavir in reference
to the active base.
DRUG DESCRIPTION



What are the possible side effects of saquinavir (Invirase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or...
Read All Potential Side Effects for Invirase »




INVIRASE brand of saquinavir mesylate is an inhibitor of the human immunodeficiency
virus (HIV) protease. INVIRASE is available as light brown and green, opaque
hard gelatin capsules for oral administration in a 200-mg strength (as saquinavir
free base). Each capsule also contains the inactive ingredients lactose, microcrystalline
cellulose, povidone K30, sodium starch glycolate, talc, and magnesium stearate.
Each capsule shell contains gelatin and water with the following dye systems:
red iron oxide, yellow iron oxide, black iron oxide, FD&C Blue #2, and titanium
dioxide.
INVIRASE is also available as a light orange to greyish- or brownish-orange,
oval cylindrical, biconvex film-coated tablet for oral administration in a 500-mg
strength (as saquinavir free base). Each tablet also contains the inactive ingredients
lactose, microcrystalline cellulose, povidone K30, croscarmellose sodium, and
magnesium stearate. Each film coat contains hypromellose, titanium dioxide,
talc, iron oxide yellow, iron oxide red, and triacetin.
The chemical name for saquinavir mesylate is N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)isoquinoline-3(S)-carboxamide
methanesulfonate with a molecular formula C38H50N6O5路CH4O3S
and a molecular weight of 766.96. The molecular weight of the free base is 670.86.
Saquinavir mesylate has the following structural formula:








Saquinavir mesylate is a white to off-white, very fine powder with an aqueous
solubility of 2.22 mg/mL at 25°C.
1 The term “saquinavir soft gel capsules” used in this label refers
to the drug product formerly marketed as “Fortovase” (saquinavir
200 mg soft gel capsule formulation). This formulation has been withdrawn from
the market.
Last reviewed on RxList: 5/25/2010




Invirase Drug Description
INVIRASE®
(saquinavir mesylate) Capsules and Tablets
Product identification in this document includes: INVIRASE in reference
to saquinavir mesylate; saquinavir soft gel capsules in reference to saquinavir
200 mg soft gel capsule formulation1, and saquinavir in reference
to the active base.
DRUG DESCRIPTION



What are the possible side effects of saquinavir (Invirase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or...
Read All Potential Side Effects for Invirase »




INVIRASE brand of saquinavir mesylate is an inhibitor of the human immunodeficiency
virus (HIV) protease. INVIRASE is available as light brown and green, opaque
hard gelatin capsules for oral administration in a 200-mg strength (as saquinavir
free base). Each capsule also contains the inactive ingredients lactose, microcrystalline
cellulose, povidone K30, sodium starch glycolate, talc, and magnesium stearate.
Each capsule shell contains gelatin and water with the following dye systems:
red iron oxide, yellow iron oxide, black iron oxide, FD&C Blue #2, and titanium
dioxide.
INVIRASE is also available as a light orange to greyish- or brownish-orange,
oval cylindrical, biconvex film-coated tablet for oral administration in a 500-mg
strength (as saquinavir free base). Each tablet also contains the inactive ingredients
lactose, microcrystalline cellulose, povidone K30, croscarmellose sodium, and
magnesium stearate. Each film coat contains hypromellose, titanium dioxide,
talc, iron oxide yellow, iron oxide red, and triacetin.
The chemical name for saquinavir mesylate is N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)isoquinoline-3(S)-carboxamide
methanesulfonate with a molecular formula C38H50N6O5路CH4O3S
and a molecular weight of 766.96. The molecular weight of the free base is 670.86.
Saquinavir mesylate has the following structural formula:








Saquinavir mesylate is a white to off-white, very fine powder with an aqueous
solubility of 2.22 mg/mL at 25°C.
1 The term “saquinavir soft gel capsules” used in this label refers
to the drug product formerly marketed as “Fortovase” (saquinavir
200 mg soft gel capsule formulation). This formulation has been withdrawn from
the market.
Last reviewed on RxList: 5/25/2010




Invirase Drug Description
INVIRASE®
(saquinavir mesylate) Capsules and Tablets
Product identification in this document includes: INVIRASE in reference
to saquinavir mesylate; saquinavir soft gel capsules in reference to saquinavir
200 mg soft gel capsule formulation1, and saquinavir in reference
to the active base.
DRUG DESCRIPTION



What are the possible side effects of saquinavir (Invirase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or...
Read All Potential Side Effects for Invirase »




INVIRASE brand of saquinavir mesylate is an inhibitor of the human immunodeficiency
virus (HIV) protease. INVIRASE is available as light brown and green, opaque
hard gelatin capsules for oral administration in a 200-mg strength (as saquinavir
free base). Each capsule also contains the inactive ingredients lactose, microcrystalline
cellulose, povidone K30, sodium starch glycolate, talc, and magnesium stearate.
Each capsule shell contains gelatin and water with the following dye systems:
red iron oxide, yellow iron oxide, black iron oxide, FD&C Blue #2, and titanium
dioxide.
INVIRASE is also available as a light orange to greyish- or brownish-orange,
oval cylindrical, biconvex film-coated tablet for oral administration in a 500-mg
strength (as saquinavir free base). Each tablet also contains the inactive ingredients
lactose, microcrystalline cellulose, povidone K30, croscarmellose sodium, and
magnesium stearate. Each film coat contains hypromellose, titanium dioxide,
talc, iron oxide yellow, iron oxide red, and triacetin.
The chemical name for saquinavir mesylate is N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)isoquinoline-3(S)-carboxamide
methanesulfonate with a molecular formula C38H50N6O5路CH4O3S
and a molecular weight of 766.96. The molecular weight of the free base is 670.86.
Saquinavir mesylate has the following structural formula:








Saquinavir mesylate is a white to off-white, very fine powder with an aqueous
solubility of 2.22 mg/mL at 25°C.
1 The term “saquinavir soft gel capsules” used in this label refers
to the drug product formerly marketed as “Fortovase” (saquinavir
200 mg soft gel capsule formulation). This formulation has been withdrawn from
the market.
Last reviewed on RxList: 5/25/2010




Invirase Drug Description
INVIRASE®
(saquinavir mesylate) Capsules and Tablets
Product identification in this document includes: INVIRASE in reference
to saquinavir mesylate; saquinavir soft gel capsules in reference to saquinavir
200 mg soft gel capsule formulation1, and saquinavir in reference
to the active base.
DRUG DESCRIPTION



What are the possible side effects of saquinavir (Invirase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or...
Read All Potential Side Effects for Invirase »




INVIRASE brand of saquinavir mesylate is an inhibitor of the human immunodeficiency
virus (HIV) protease. INVIRASE is available as light brown and green, opaque
hard gelatin capsules for oral administration in a 200-mg strength (as saquinavir
free base). Each capsule also contains the inactive ingredients lactose, microcrystalline
cellulose, povidone K30, sodium starch glycolate, talc, and magnesium stearate.
Each capsule shell contains gelatin and water with the following dye systems:
red iron oxide, yellow iron oxide, black iron oxide, FD&C Blue #2, and titanium
dioxide.
INVIRASE is also available as a light orange to greyish- or brownish-orange,
oval cylindrical, biconvex film-coated tablet for oral administration in a 500-mg
strength (as saquinavir free base). Each tablet also contains the inactive ingredients
lactose, microcrystalline cellulose, povidone K30, croscarmellose sodium, and
magnesium stearate. Each film coat contains hypromellose, titanium dioxide,
talc, iron oxide yellow, iron oxide red, and triacetin.
The chemical name for saquinavir mesylate is N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)isoquinoline-3(S)-carboxamide
methanesulfonate with a molecular formula C38H50N6O5路CH4O3S
and a molecular weight of 766.96. The molecular weight of the free base is 670.86.
Saquinavir mesylate has the following structural formula:








Saquinavir mesylate is a white to off-white, very fine powder with an aqueous
solubility of 2.22 mg/mL at 25°C.
1 The term “saquinavir soft gel capsules” used in this label refers
to the drug product formerly marketed as “Fortovase” (saquinavir
200 mg soft gel capsule formulation). This formulation has been withdrawn from
the market.
Last reviewed on RxList: 5/25/2010




Invirase Drug Description
INVIRASE®
(saquinavir mesylate) Capsules and Tablets
Product identification in this document includes: INVIRASE in reference
to saquinavir mesylate; saquinavir soft gel capsules in reference to saquinavir
200 mg soft gel capsule formulation1, and saquinavir in reference
to the active base.
DRUG DESCRIPTION



What are the possible side effects of saquinavir (Invirase)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or...
Read All Potential Side Effects for Invirase »




INVIRASE brand of saquinavir mesylate is an inhibitor of the human immunodeficiency
virus (HIV) protease. INVIRASE is available as light brown and green, opaque
hard gelatin capsules for oral administration in a 200-mg strength (as saquinavir
free base). Each capsule also contains the inactive ingredients lactose, microcrystalline
cellulose, povidone K30, sodium starch glycolate, talc, and magnesium stearate.
Each capsule shell contains gelatin and water with the following dye systems:
red iron oxide, yellow iron oxide, black iron oxide, FD&C Blue #2, and titanium
dioxide.
INVIRASE is also available as a light orange to greyish- or brownish-orange,
oval cylindrical, biconvex film-coated tablet for oral administration in a 500-mg
strength (as saquinavir free base). Each tablet also contains the inactive ingredients
lactose, microcrystalline cellulose, povidone K30, croscarmellose sodium, and
magnesium stearate. Each film coat contains hypromellose, titanium dioxide,
talc, iron oxide yellow, iron oxide red, and triacetin.
The chemical name for saquinavir mesylate is N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)isoquinoline-3(S)-carboxamide
methanesulfonate with a molecular formula C38H50N6O5路CH4O3S
and a molecular weight of 766.96. The molecular weight of the free base is 670.86.
Saquinavir mesylate has the following structural formula:








Saquinavir mesylate is a white to off-white, very fine powder with an aqueous
solubility of 2.22 mg/mL at 25°C.
1 The term “saquinavir soft gel capsules” used in this label refers
to the drug product formerly marketed as “Fortovase” (saquinavir
200 mg soft gel capsule formulation). This formulation has been withdrawn from
the market.
Last reviewed on RxList: 5/25/2010





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  by irbtipoftheweek
FDA notified healthcare professionals and patients that it is reviewing clinical trial data about a potentially serious effect on the heart from the use of Invirase (saquinavir) in […]


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***** TODAY鈥橲 NEWS Why one hospital is restricting drug sales reps (news clip). Interesting perspectives on sampling. Possible heart problem with HIV drug combo - The U.S. Food and […]


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FDA NEWS RELEASEFor Immediate Release: Feb. 23, 2010Media Inquiries: Erica Jefferson, 301-796-4988; erica.jefferson@fda.hhs.govConsumer Inquiries: 888-INFO-FDA( from medscape for iphone)Review of data indicating life-threatening heart abnormality underwayThe U.S. Food […]


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Los Angeles Times聽聽聽聽 (02.23.10) On Tuesday, the Food and Drug Administration issued an announcement about an ongoing safety review of the combination of HIV drugs Invirase (saquinavir) and Norvir […]


Drug Information Update - Ongoing safety review of Invirase (saquinavir) and possible association with abnormal heart rhythms
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聽FDA's analysis of these data is ongoing. However, healthcare professionals should be aware of this potential risk for changes to the electrical activity of the heart. Invirase and […]


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Other reviews about Invirase on web:

Saquinavir mesylate. Product information for US residents. Genentech: Medicines: Invirase


Learn about the prescription medication Invirase (Saquinavir Mesylate), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Invirase (Saquinavir Mesylate) Drug Information: Uses, Side ...


Accurate, FDA approved Invirase information for healthcare professionals and patients - brought to you by Drugs.com. Invirase Official FDA information, side effects and uses.


Invirase (saquinavir) is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Includes Invirase side effects, interactions and indications. Invirase Information from Drugs.com


Roche announced in May 2005 that, owing to reduction in demand, Fortovase would cease being marketed early in 2006 in favour of Invirase boosted with ritonavir. Saquinavir - Wikipedia, the free encyclopedia


Complete info about Invirase (saquinavir), a protease inhibitor ... Invirase belongs to a class of anti-HIV drugs called Protease Inhibitors (PIs). AIDSmeds.com - Invirase


Invirase is an HIV protease inhibitor used in combination with other medicines to treat human immunodeficiency virus (HIV) infection. Side effects and interactions are available at ... Invirase - drugstore.com. Low prices, side effects, interactions.


Invirase is typically prescribed to treat HIV or AIDS. This selection from the eMedTV Web site provides an overview of this medication, including information on how it works ... Invirase


Why It Is Prescribed. Saquinavir is used in combination with other medications to treat human immunodeficiency virus (HIV) infection in patients with or without acquired ... Invirase - Kosmix : Reference, Videos, Images, News, Shopping and ...


1 INVI RASE 脙聜脗庐 (saquinavir mesylate) CAPSULES and TABLETS Product identification in this document includes: INVIRASE in reference to saquinavir mesylate; saquinavir soft gel capsules in ... INVI RASE脙聜脗庐 (saquinavir mesylate)





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