Reviews Interferon beta-1a


No reviews yet.

Avonex Drug Description
AVONEX®
(Interferon beta-1a) IM Injection
DRUG DESCRIPTION



What are the possible side effects of interferon beta-1a (Avonex, Avonex Prefilled Syringe, Rebif)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
easy bruising or bleeding, weakness;
seizure (convulsions);
numbness or tingling in your...
Read All Potential Side Effects for Avonex »




AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted
molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into
which the human interferon beta gene has been introduced. The amino acid sequence
of AVONEX® is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) natural interferon beta standard,
Second International Standard for Interferon, Human Fibroblast (Gb-23-902-531),
AVONEX® has a specific activity of approximately 200 million international
units (IU) of antiviral activity per mg of Interferon beta-1a determined specifically
by an in vitro cytopathic effect bioassay using lung carcinoma cells
(A549) and Encephalomyocarditis virus (ECM). AVONEX® 30 mcg contains approximately
6 million IU of antiviral activity using this method. The activity against other
standards is not known. Comparison of the activity of AVONEX® with other
Interferon betas is not appropriate, because of differences in the reference
standards and assays used to measure activity.
30 mcg Lyophilized Powder Vial
A vial of AVONEX® is formulated as a sterile, white to off-white lyophilized
powder for intramuscular injection after reconstitution with supplied diluent
(Sterile Water for Injection, USP). Each vial of reconstituted AVONEX® contains
30 mcg of Interferon beta-1a; 15 mg Albumin (Human), USP; 5.8 mg Sodium Chloride,
USP; 5.7 mg Dibasic Sodium Phosphate, USP; and 1.2 mg Monobasic Sodium Phosphate,
USP, in 1.0 mL at a pH of approximately 7.3.
30 mcg Prefilled Syringe
A prefilled syringe of AVONEX® is formulated as a sterile liquid for intramuscular
injection. Each 0.5 mL (30 mcg dose) of AVONEX® in a prefilled glass syringe
contains 30 mcg of Interferon beta-1a, 0.79 mg Sodium Acetate Trihydrate, USP;
0.25 mg Glacial Acetic Acid, USP; 15.8 mg Arginine Hydrochloride, USP; and 0.025
mg Polysorbate 20 in Water for Injection, USP at a pH of approximately 4.8.
Last reviewed on RxList: 2/21/2008




Avonex Drug Description
AVONEX®
(Interferon beta-1a) IM Injection
DRUG DESCRIPTION



What are the possible side effects of interferon beta-1a (Avonex, Avonex Prefilled Syringe, Rebif)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
easy bruising or bleeding, weakness;
seizure (convulsions);
numbness or tingling in your...
Read All Potential Side Effects for Avonex »




AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted
molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into
which the human interferon beta gene has been introduced. The amino acid sequence
of AVONEX® is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) natural interferon beta standard,
Second International Standard for Interferon, Human Fibroblast (Gb-23-902-531),
AVONEX® has a specific activity of approximately 200 million international
units (IU) of antiviral activity per mg of Interferon beta-1a determined specifically
by an in vitro cytopathic effect bioassay using lung carcinoma cells
(A549) and Encephalomyocarditis virus (ECM). AVONEX® 30 mcg contains approximately
6 million IU of antiviral activity using this method. The activity against other
standards is not known. Comparison of the activity of AVONEX® with other
Interferon betas is not appropriate, because of differences in the reference
standards and assays used to measure activity.
30 mcg Lyophilized Powder Vial
A vial of AVONEX® is formulated as a sterile, white to off-white lyophilized
powder for intramuscular injection after reconstitution with supplied diluent
(Sterile Water for Injection, USP). Each vial of reconstituted AVONEX® contains
30 mcg of Interferon beta-1a; 15 mg Albumin (Human), USP; 5.8 mg Sodium Chloride,
USP; 5.7 mg Dibasic Sodium Phosphate, USP; and 1.2 mg Monobasic Sodium Phosphate,
USP, in 1.0 mL at a pH of approximately 7.3.
30 mcg Prefilled Syringe
A prefilled syringe of AVONEX® is formulated as a sterile liquid for intramuscular
injection. Each 0.5 mL (30 mcg dose) of AVONEX® in a prefilled glass syringe
contains 30 mcg of Interferon beta-1a, 0.79 mg Sodium Acetate Trihydrate, USP;
0.25 mg Glacial Acetic Acid, USP; 15.8 mg Arginine Hydrochloride, USP; and 0.025
mg Polysorbate 20 in Water for Injection, USP at a pH of approximately 4.8.
Last reviewed on RxList: 2/21/2008




Avonex Drug Description
AVONEX®
(Interferon beta-1a) IM Injection
DRUG DESCRIPTION



What are the possible side effects of interferon beta-1a (Avonex, Avonex Prefilled Syringe, Rebif)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
easy bruising or bleeding, weakness;
seizure (convulsions);
numbness or tingling in your...
Read All Potential Side Effects for Avonex »




AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted
molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into
which the human interferon beta gene has been introduced. The amino acid sequence
of AVONEX® is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) natural interferon beta standard,
Second International Standard for Interferon, Human Fibroblast (Gb-23-902-531),
AVONEX® has a specific activity of approximately 200 million international
units (IU) of antiviral activity per mg of Interferon beta-1a determined specifically
by an in vitro cytopathic effect bioassay using lung carcinoma cells
(A549) and Encephalomyocarditis virus (ECM). AVONEX® 30 mcg contains approximately
6 million IU of antiviral activity using this method. The activity against other
standards is not known. Comparison of the activity of AVONEX® with other
Interferon betas is not appropriate, because of differences in the reference
standards and assays used to measure activity.
30 mcg Lyophilized Powder Vial
A vial of AVONEX® is formulated as a sterile, white to off-white lyophilized
powder for intramuscular injection after reconstitution with supplied diluent
(Sterile Water for Injection, USP). Each vial of reconstituted AVONEX® contains
30 mcg of Interferon beta-1a; 15 mg Albumin (Human), USP; 5.8 mg Sodium Chloride,
USP; 5.7 mg Dibasic Sodium Phosphate, USP; and 1.2 mg Monobasic Sodium Phosphate,
USP, in 1.0 mL at a pH of approximately 7.3.
30 mcg Prefilled Syringe
A prefilled syringe of AVONEX® is formulated as a sterile liquid for intramuscular
injection. Each 0.5 mL (30 mcg dose) of AVONEX® in a prefilled glass syringe
contains 30 mcg of Interferon beta-1a, 0.79 mg Sodium Acetate Trihydrate, USP;
0.25 mg Glacial Acetic Acid, USP; 15.8 mg Arginine Hydrochloride, USP; and 0.025
mg Polysorbate 20 in Water for Injection, USP at a pH of approximately 4.8.
Last reviewed on RxList: 2/21/2008




Avonex Drug Description
AVONEX®
(Interferon beta-1a) IM Injection
DRUG DESCRIPTION



What are the possible side effects of interferon beta-1a (Avonex, Avonex Prefilled Syringe, Rebif)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
easy bruising or bleeding, weakness;
seizure (convulsions);
numbness or tingling in your...
Read All Potential Side Effects for Avonex »




AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted
molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into
which the human interferon beta gene has been introduced. The amino acid sequence
of AVONEX® is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) natural interferon beta standard,
Second International Standard for Interferon, Human Fibroblast (Gb-23-902-531),
AVONEX® has a specific activity of approximately 200 million international
units (IU) of antiviral activity per mg of Interferon beta-1a determined specifically
by an in vitro cytopathic effect bioassay using lung carcinoma cells
(A549) and Encephalomyocarditis virus (ECM). AVONEX® 30 mcg contains approximately
6 million IU of antiviral activity using this method. The activity against other
standards is not known. Comparison of the activity of AVONEX® with other
Interferon betas is not appropriate, because of differences in the reference
standards and assays used to measure activity.
30 mcg Lyophilized Powder Vial
A vial of AVONEX® is formulated as a sterile, white to off-white lyophilized
powder for intramuscular injection after reconstitution with supplied diluent
(Sterile Water for Injection, USP). Each vial of reconstituted AVONEX® contains
30 mcg of Interferon beta-1a; 15 mg Albumin (Human), USP; 5.8 mg Sodium Chloride,
USP; 5.7 mg Dibasic Sodium Phosphate, USP; and 1.2 mg Monobasic Sodium Phosphate,
USP, in 1.0 mL at a pH of approximately 7.3.
30 mcg Prefilled Syringe
A prefilled syringe of AVONEX® is formulated as a sterile liquid for intramuscular
injection. Each 0.5 mL (30 mcg dose) of AVONEX® in a prefilled glass syringe
contains 30 mcg of Interferon beta-1a, 0.79 mg Sodium Acetate Trihydrate, USP;
0.25 mg Glacial Acetic Acid, USP; 15.8 mg Arginine Hydrochloride, USP; and 0.025
mg Polysorbate 20 in Water for Injection, USP at a pH of approximately 4.8.
Last reviewed on RxList: 2/21/2008




Avonex Drug Description
AVONEX®
(Interferon beta-1a) IM Injection
DRUG DESCRIPTION



What are the possible side effects of interferon beta-1a (Avonex, Avonex Prefilled Syringe, Rebif)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
easy bruising or bleeding, weakness;
seizure (convulsions);
numbness or tingling in your...
Read All Potential Side Effects for Avonex »




AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted
molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into
which the human interferon beta gene has been introduced. The amino acid sequence
of AVONEX® is identical to that of natural human interferon beta.
Using the World Health Organization (WHO) natural interferon beta standard,
Second International Standard for Interferon, Human Fibroblast (Gb-23-902-531),
AVONEX® has a specific activity of approximately 200 million international
units (IU) of antiviral activity per mg of Interferon beta-1a determined specifically
by an in vitro cytopathic effect bioassay using lung carcinoma cells
(A549) and Encephalomyocarditis virus (ECM). AVONEX® 30 mcg contains approximately
6 million IU of antiviral activity using this method. The activity against other
standards is not known. Comparison of the activity of AVONEX® with other
Interferon betas is not appropriate, because of differences in the reference
standards and assays used to measure activity.
30 mcg Lyophilized Powder Vial
A vial of AVONEX® is formulated as a sterile, white to off-white lyophilized
powder for intramuscular injection after reconstitution with supplied diluent
(Sterile Water for Injection, USP). Each vial of reconstituted AVONEX® contains
30 mcg of Interferon beta-1a; 15 mg Albumin (Human), USP; 5.8 mg Sodium Chloride,
USP; 5.7 mg Dibasic Sodium Phosphate, USP; and 1.2 mg Monobasic Sodium Phosphate,
USP, in 1.0 mL at a pH of approximately 7.3.
30 mcg Prefilled Syringe
A prefilled syringe of AVONEX® is formulated as a sterile liquid for intramuscular
injection. Each 0.5 mL (30 mcg dose) of AVONEX® in a prefilled glass syringe
contains 30 mcg of Interferon beta-1a, 0.79 mg Sodium Acetate Trihydrate, USP;
0.25 mg Glacial Acetic Acid, USP; 15.8 mg Arginine Hydrochloride, USP; and 0.025
mg Polysorbate 20 in Water for Injection, USP at a pH of approximately 4.8.
Last reviewed on RxList: 2/21/2008





Other reviews about Interferon beta-1a on wordpress

Rash from interferon beta-1a (Betaseron and Rebif)
  by Thixia
 Widespread rash due to intramuscular interferon beta-1a during the treatment of multiple sclerosis.     We describe a 41-year-old woman with multiple sclerosis, who presented with redness of the skin; several […]


The different MS Drugs - a comparison
  by sofija
Drug Name Interferon beta-1a (Avonex) Description Prescribed in USA as Avonex, administered by IM route (Biogen). Avonex is indicated for treatment of patients with relapsing forms of […]


New Data on Disease-modifying Therapies for Multiple Sclerosis
  by Yasser Metwally
The author: Professor Yasser Metwally http://yassermetwally.com INTRODUCTION June 2, 2008 — New data from key clinical trials of disease-modifying therapy were presented at the 60th Annual Meeting of the American Academy […]


Interferon Beta-1a 15-Year Long-Term Follow-up Study
  by Thixia
Intramuscular Interferon Beta-1a Reduces Disability Progression and Improves Quality of Life in Relapsing Multiple Sclerosis: Presented at WCTRMS   MONTREAL, QUEBEC, CANADA –     Patients who have been taking intramuscular interferon […]


New Drug For MS
  by Johannes
Multiple sclerosis, or MS, is an autoimmune disease where the body's immune system attacks the myelin sheets around the neuronal axons, which causes disturbance in the conduction of […]


New hope for multiple sclerosis sufferers
  by Snowcrash
A drug which was developed in Cambridge and initially designed to treat a form of leukaemia has also proven effective against combating the debilitating neurological disease multiple sclerosis […]


No more injections for MS patients..? nice :o)
  by sofija
New Interferon formulations promise to eliminate injections in MS treatment. This is great news for all of us "needle-lovers" :o) Nerveda Inc. and Aegis Therapeutics LLC announced on January […]


Methylprednisolone plus IFN beta and relapsing-remitting MS: the NORMIMS study | News | MS Trust - Information, education, research and support
  by boldwheels
Image via WikipediaMethylprednisolone plus IFN beta and relapsing-remitting MS: the NORMIMS study | News | MS Trust - Information, education, research and support: "Adding oral methylprednisolone (MP) to […]


Understanding multiple sclerosis
  by techris
Understanding multiple sclerosis. the Sunday Times website, Sunday 21 June. Quite a simple and relatively easy to follow explanation. "Many have heard the tongue-twister, Multiple Sclerosis (MS), but given it scant […]


Neuropharmacology section: Immunomodulators in multiple sclerosis
  by Yasser Metwally
The author: Professor Yasser Metwally http://yassermetwally.com INTRODUCTION December 30, 2009 — Immunomodulators  delay progression to disability […]



Other reviews about Interferon beta-1a on web:

Interferon beta-1a is a drug in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian cells while Interferon beta-1b is produced in modified ... Interferon beta-1a - Wikipedia, the free encyclopedia


Interferon Beta-1a Brand names: Avonex®Rebif Titration PackRebif® Drug Forms: Interferon Beta-1a Solution for injection (below) Interferon Interferon beta-1a: Information from Answers.com


Learn about the prescription medication Avonex (Interferon beta-1a), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Avonex (Interferon beta-1a) Drug Information: Uses, Side Effects ...


All about Interferon Beta-1a. View complete and up to date Interferon Beta-1a information - part of the Drugs.com trusted medication database. Interferon Beta-1a Facts and Comparisons at Drugs.com


Physician reviewed interferon beta-1a patient information - includes interferon beta-1a description, dosage and directions. interferon beta-1a medical facts from Drugs.com


interferon beta-1a, an antiviral and immune system regulator. indications It is prescribed in the treatment of relapsing forms of multiple sclerosis. interferon beta-1a - definition of interferon beta-1a in the ...


Resource URI: http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00060 Interferon beta-1a | D2R Server publishing the DrugBank Database


Find patient medical information for Interferon Beta-1a IM on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Interferon Beta-1a IM : Uses, Side Effects, Interactions, Pictures ...


Interferon beta-1a is used to prevent episodes of symptoms and slow the development of disability in patients with relapsing-remitting multiple sclerosis (MS, a disease in ... Interferon beta-1a Subcutaneous Injection: MedlinePlus Drug ...


Interferon beta-1a is a medication that is prescribed for the treatment of multiple sclerosis. This eMedTV page describes the two different forms of interferon beta-1a ... Interferon Beta-1a





Featured Reviews

Reviews Multitrace 5 Concentrate

Multitrace 5 Concentrate Drug Description MULTITRACE® - 5 CONCENTRATE (trace elements) Injection 5 FOR IV USE AFTER DILUTION DRUG DESCRIPTION MULTITRACE® - 5 CONCENTRATE (TRACE ELEMENTS INJECTION 5, USP) is a sterile nonpyrogenic...
Read More  |  Review This
Reviews Flurbiprofen

Ansaid Drug Description Ansaid® (flurbiprofen) Tablets, USP 50 mg and 100 mg Cardiovascular Risk NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can...
Read More  |  Review This
Reviews Sectral

Sectral Drug Description Sectral® (acebutolol hydrochloride) Capsules DRUG DESCRIPTION What are the possible side effects of acebutolol (Sectral)? Get emergency medical help if you have any of these signs of an allergic reaction:...
Read More  |  Review This
Reviews Avandia

Avandia Drug Description AVANDIA® (rosiglitazone maleate) Tablets WARNING CONGESTIVE HEART FAILURE AND MYOCARDIAL ISCHEMIA Thiazolidinediones, including rosiglitazone, cause or exacerbate congestive heart failure in some...
Read More  |  Review This
Reviews Candesartan Cilexetil

Atacand Drug Description ATACAND® (candesartan cilexetil) Tablets WARNING USE IN PREGNANCY: When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury...
Read More  |  Review This
Recent News
59sec - the BEST lead management system around!
We tested 59sec - THE lead management system and we love it. 59sec helps small and medium companies to answer leads in maximum 59 seconds. Why...
MOVEorPAY - our favorite facebook app
We do love MOVEorPAY motivational facebook app, because it is very cool and useful. It makes you finish stuff that you know are good for you, but from various reasons, you never do...
ReviewsAZ is almost ready to be officially launched
yes, we have just a few loose ends to tie and we are ready to go :) meanwhile, I am putting some reviews on the site, so people will not get an empty site at the launch....