Reviews Immune Globulin


No reviews yet.

Baygam Drug Description
BayGam™
Immune Globulin (Human)
Solvent/Detergent Treated
DRUG DESCRIPTION
Immune Globulin (Human) — BayGam™ treated with solvent/detergent is a
sterile solution of immune globulin for intramuscular administration; it contains
no preservative. BayGam is prepared by cold ethanol fractionation from human
plasma. The immune globulin is isolated from solubilized Cohn fraction II. The
fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl
phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP)
and detergent (sodium cholate), the solution is heated to 30°C and maintained
at that temperature for not less than 6 hours. After the viral inactivation
step, the reactants are removed by precipitation, filtration and finally ultrafiltration
and diafiltra-tion. BayGam is formulated as a 15–18% protein solution at a pH
of 6.4–7.2 in 0.21–0.32 M glycine. BayGam is then incubated in the final container
for 21–28 days at 20–27°C.
The removal and inactivation of spiked model enveloped and non-enveloped viruses
during the manufacturing process for BayGam has been validated in laboratory
studies. Human Immunodeficiency Virus, Type 1 (HIV-1), was chosen as the relevant
virus for blood products; Bovine Viral Diarrhea Virus (BVDV) was chosen to model
Hepatitis C virus; Pseudorabies virus (PRV) was chosen to model Hepatitis B
virus and the Herpes viruses; and Reo virus type 3 (Reo) was chosen to model
non-enveloped viruses and for its resistance to physical and chemical inactivation.
Significant removal of model enveloped and non-enveloped viruses is achieved
at two steps in the Cohn fractionation process leading to the collection of
Cohn Fraction II:the precipitation and removal of Fraction III in the processing
of Fraction II + IIIW suspension to Effluent IIIand the filtration step in the
processing of Effluent III to Filtrate III. Significant inactivation of enveloped
viruses is achieved at the time of treatment of solubilized Cohn Fraction II
with TNBP/sodium cholate.Last reviewed on RxList: 11/13/2008




Baygam Drug Description
BayGam™
Immune Globulin (Human)
Solvent/Detergent Treated
DRUG DESCRIPTION
Immune Globulin (Human) — BayGam™ treated with solvent/detergent is a
sterile solution of immune globulin for intramuscular administration; it contains
no preservative. BayGam is prepared by cold ethanol fractionation from human
plasma. The immune globulin is isolated from solubilized Cohn fraction II. The
fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl
phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP)
and detergent (sodium cholate), the solution is heated to 30°C and maintained
at that temperature for not less than 6 hours. After the viral inactivation
step, the reactants are removed by precipitation, filtration and finally ultrafiltration
and diafiltra-tion. BayGam is formulated as a 15–18% protein solution at a pH
of 6.4–7.2 in 0.21–0.32 M glycine. BayGam is then incubated in the final container
for 21–28 days at 20–27°C.
The removal and inactivation of spiked model enveloped and non-enveloped viruses
during the manufacturing process for BayGam has been validated in laboratory
studies. Human Immunodeficiency Virus, Type 1 (HIV-1), was chosen as the relevant
virus for blood products; Bovine Viral Diarrhea Virus (BVDV) was chosen to model
Hepatitis C virus; Pseudorabies virus (PRV) was chosen to model Hepatitis B
virus and the Herpes viruses; and Reo virus type 3 (Reo) was chosen to model
non-enveloped viruses and for its resistance to physical and chemical inactivation.
Significant removal of model enveloped and non-enveloped viruses is achieved
at two steps in the Cohn fractionation process leading to the collection of
Cohn Fraction II:the precipitation and removal of Fraction III in the processing
of Fraction II + IIIW suspension to Effluent IIIand the filtration step in the
processing of Effluent III to Filtrate III. Significant inactivation of enveloped
viruses is achieved at the time of treatment of solubilized Cohn Fraction II
with TNBP/sodium cholate.Last reviewed on RxList: 11/13/2008




Baygam Drug Description
BayGam™
Immune Globulin (Human)
Solvent/Detergent Treated
DRUG DESCRIPTION
Immune Globulin (Human) — BayGam™ treated with solvent/detergent is a
sterile solution of immune globulin for intramuscular administration; it contains
no preservative. BayGam is prepared by cold ethanol fractionation from human
plasma. The immune globulin is isolated from solubilized Cohn fraction II. The
fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl
phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP)
and detergent (sodium cholate), the solution is heated to 30°C and maintained
at that temperature for not less than 6 hours. After the viral inactivation
step, the reactants are removed by precipitation, filtration and finally ultrafiltration
and diafiltra-tion. BayGam is formulated as a 15–18% protein solution at a pH
of 6.4–7.2 in 0.21–0.32 M glycine. BayGam is then incubated in the final container
for 21–28 days at 20–27°C.
The removal and inactivation of spiked model enveloped and non-enveloped viruses
during the manufacturing process for BayGam has been validated in laboratory
studies. Human Immunodeficiency Virus, Type 1 (HIV-1), was chosen as the relevant
virus for blood products; Bovine Viral Diarrhea Virus (BVDV) was chosen to model
Hepatitis C virus; Pseudorabies virus (PRV) was chosen to model Hepatitis B
virus and the Herpes viruses; and Reo virus type 3 (Reo) was chosen to model
non-enveloped viruses and for its resistance to physical and chemical inactivation.
Significant removal of model enveloped and non-enveloped viruses is achieved
at two steps in the Cohn fractionation process leading to the collection of
Cohn Fraction II:the precipitation and removal of Fraction III in the processing
of Fraction II + IIIW suspension to Effluent IIIand the filtration step in the
processing of Effluent III to Filtrate III. Significant inactivation of enveloped
viruses is achieved at the time of treatment of solubilized Cohn Fraction II
with TNBP/sodium cholate.Last reviewed on RxList: 11/13/2008




Baygam Drug Description
BayGam™
Immune Globulin (Human)
Solvent/Detergent Treated
DRUG DESCRIPTION
Immune Globulin (Human) — BayGam™ treated with solvent/detergent is a
sterile solution of immune globulin for intramuscular administration; it contains
no preservative. BayGam is prepared by cold ethanol fractionation from human
plasma. The immune globulin is isolated from solubilized Cohn fraction II. The
fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl
phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP)
and detergent (sodium cholate), the solution is heated to 30°C and maintained
at that temperature for not less than 6 hours. After the viral inactivation
step, the reactants are removed by precipitation, filtration and finally ultrafiltration
and diafiltra-tion. BayGam is formulated as a 15–18% protein solution at a pH
of 6.4–7.2 in 0.21–0.32 M glycine. BayGam is then incubated in the final container
for 21–28 days at 20–27°C.
The removal and inactivation of spiked model enveloped and non-enveloped viruses
during the manufacturing process for BayGam has been validated in laboratory
studies. Human Immunodeficiency Virus, Type 1 (HIV-1), was chosen as the relevant
virus for blood products; Bovine Viral Diarrhea Virus (BVDV) was chosen to model
Hepatitis C virus; Pseudorabies virus (PRV) was chosen to model Hepatitis B
virus and the Herpes viruses; and Reo virus type 3 (Reo) was chosen to model
non-enveloped viruses and for its resistance to physical and chemical inactivation.
Significant removal of model enveloped and non-enveloped viruses is achieved
at two steps in the Cohn fractionation process leading to the collection of
Cohn Fraction II:the precipitation and removal of Fraction III in the processing
of Fraction II + IIIW suspension to Effluent IIIand the filtration step in the
processing of Effluent III to Filtrate III. Significant inactivation of enveloped
viruses is achieved at the time of treatment of solubilized Cohn Fraction II
with TNBP/sodium cholate.Last reviewed on RxList: 11/13/2008




Baygam Drug Description
BayGam™
Immune Globulin (Human)
Solvent/Detergent Treated
DRUG DESCRIPTION
Immune Globulin (Human) — BayGam™ treated with solvent/detergent is a
sterile solution of immune globulin for intramuscular administration; it contains
no preservative. BayGam is prepared by cold ethanol fractionation from human
plasma. The immune globulin is isolated from solubilized Cohn fraction II. The
fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl
phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP)
and detergent (sodium cholate), the solution is heated to 30°C and maintained
at that temperature for not less than 6 hours. After the viral inactivation
step, the reactants are removed by precipitation, filtration and finally ultrafiltration
and diafiltra-tion. BayGam is formulated as a 15–18% protein solution at a pH
of 6.4–7.2 in 0.21–0.32 M glycine. BayGam is then incubated in the final container
for 21–28 days at 20–27°C.
The removal and inactivation of spiked model enveloped and non-enveloped viruses
during the manufacturing process for BayGam has been validated in laboratory
studies. Human Immunodeficiency Virus, Type 1 (HIV-1), was chosen as the relevant
virus for blood products; Bovine Viral Diarrhea Virus (BVDV) was chosen to model
Hepatitis C virus; Pseudorabies virus (PRV) was chosen to model Hepatitis B
virus and the Herpes viruses; and Reo virus type 3 (Reo) was chosen to model
non-enveloped viruses and for its resistance to physical and chemical inactivation.
Significant removal of model enveloped and non-enveloped viruses is achieved
at two steps in the Cohn fractionation process leading to the collection of
Cohn Fraction II:the precipitation and removal of Fraction III in the processing
of Fraction II + IIIW suspension to Effluent IIIand the filtration step in the
processing of Effluent III to Filtrate III. Significant inactivation of enveloped
viruses is achieved at the time of treatment of solubilized Cohn Fraction II
with TNBP/sodium cholate.Last reviewed on RxList: 11/13/2008





Other reviews about Immune Globulin on wordpress

Hepatitis A Vaccine Better than Immune Globulin
  by SearchMedica
Given after exposure, the hepatitis A vaccine provides as much protection against hepatitis A as immune globulin, according to a new randomized study in the New England Journal […]


Readers' Questions Regarding Rh-immune Globulin
  by heremias
Like GBS (see our last post), another common source of questions and confusion in uncomplicated pregnancies is the significance of being an Rh-negative woman. It is another one […]


Chemo Recovery - Week 1
  by Debora Dale
Hello from Colorado! Still no elk or deer sightings. :-( Yesterday was my grandmother's 94th birthday. Ninety-fourth!! One of the cards she received was musical and played the birthday […]


Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation
  by journaldokter
Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation Ashley A. Vo, Pharm.D., Marina Lukovsky, Pharm.D., Mieko Toyoda, Ph.D., Jennifer Wang, M.D., Nancy L. Reinsmoen, Ph.D., Chih-Hung Lai, […]


Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation
  by journaldokter
Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation Ashley A. Vo, Pharm.D., Marina Lukovsky, Pharm.D., Mieko Toyoda, Ph.D., Jennifer Wang, M.D., Nancy L. Reinsmoen, Ph.D., Chih-Hung Lai, […]


Hepatitis A Vaccine versus Immune Globulin for Postexposure Prophylaxis
  by andrewcraig
Source:N Engl J Med. 2007, 357(17) p. 1685-94 For abstract link here Year of publication: 2009 Publication Type: Journal Article Length of Publication: 10 page article In a nutshell: Background Hepatitis A […]


H1N1 (Swine Flu): Marketing Hand Washing to Kids and Low Levels of Immune Globulin May Lead to Severe Disease in Pregnant Women
  by Regina Phelps EMS Solutions
MARKETING HAND WASHING TO KIDS I suppose it was only a matter of time….The Disney corporation is now marketing Musical Hand Wash Timers featuring characters like the Little Mermaid, […]


Childhood Immunizations Pennsylvania
  by pittsburghbusiness
Today, children in the United States routinely get vaccines that protect them from more than a dozen diseases such as measles, polio and tetanus. Most of these diseases […]


Oh, oh, $100,000 in the hole...
  by WendyUsuallyWanders
I just spent 2 1/2 hours in the hospital. The nurse put an IV in me, then went to order the immune globulin from the pharmacy. Finally I […]


Rho(D) immune globulin I.V.
  by bookjunglejm
Wish to share this article with you all Rho(D) immune globulin I.V. WinRho SDF Pharmaceutical company: Baxter Healthcare Corporation www.baxter.com NEW WARNING Cangene Corporation and Baxter Healthcare Corporation issued a "Dear Healthcare […]



Other reviews about Immune Globulin on web:

Immune Globulin Key Terms: Autoimmune disease , Epinephrine , Immunoglobulins , Intramuscular administration , Intravenous administration Immune Globulin: Information from Answers.com


Antibodies (also known as immunoglobulins, abbreviated Ig) are gamma globulin proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immune system to ... Antibody - Wikipedia, the free encyclopedia


Consumer information about the medication IMMUNE GLOBULIN - INTRAVENOUS (Gamimune N, Gammagard, Gammar, Iveegam, Polygam, Sandoglobulin), includes side effects, drug interactions ... IMMUNE GLOBULIN - INTRAVENOUS (Gamimune N, Gammagard, Gammar ...


Immune globulin (also called gamma globulin or immune serum globulin) is a substance made from human blood plasma. The plasma, processed from donated human blood, contains ... Immune Globulin-Overview


Drug details for Immune globulin (IG) for hepatitis A. ... This drug is given by injection into a muscle (intramuscular injection). Immune globulin (IG) for hepatitis A


Features information about dosage, usage, warnings, and side effects. Immune Globulin Intravenous Injection: MedlinePlus Drug Information


Rh o (D) Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease (or hemolytic disease of ... Rho(D) immune globulin - Wikipedia, the free encyclopedia


Updates: Intravenous Immune Globulin Therapy for Neurologic Diseases . Marinos C. Dalakas; Ann Intern Med May 1, 1997 126: 721-730; doi: 10.1059/0003-4819-126-9-199705010-00008 Sign In — Ann Intern Med


All about Lymphocyte Immune Globulin. View complete and up to date Lymphocyte Immune Globulin information - part of the Drugs.com trusted medication database. Lymphocyte Immune Globulin Facts and Comparisons at Drugs.com


Rh0 [D] Immune Globulin Brand names: BayRho-D™HyperRHO™MICRhoGAM®RhoGAM®Rhophylac®WinRho® SDF Drug Forms: Rho(D) Immune Rh0 [D] Immune Globulin: Information from Answers.com





Featured Reviews

Reviews Hydrocodone Bitartrate and Acetaminophen Tablets

Lortab 7.5 Drug Description LORTAB® 7.5/500 (hydrocodone bitartrate and acetaminophen) Tablets, USP 7.5 mg/500 mg DRUG DESCRIPTION Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration. WARNING:...
Read More  |  Review This
Reviews Atacand HCT

Atacand HCT Drug Description ATACAND HCT (candesartan cilexetil - hydrochlorothiazide) Tablets USE IN PREGNANCY When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system...
Read More  |  Review This
Reviews Cyclophosphamide

Cytoxan Drug Description CYTOXAN® (cyclophosphamide) for Injection, USP CYTOXAN® Tablets (cyclophosphamide) Tablets, USP DRUG DESCRIPTION What are the possible side effects of cyclophosphamide (Cytoxan, Cytoxan Lyophilized,...
Read More  |  Review This
Reviews Retisert

Retisert Drug Description RETISERT (fluocinolone acetonide intravitreal) Implant 0.59mg DRUG DESCRIPTION What are the possible side effects of fluocinolone ophthalmic implant (Retisert)? For the first 1 to 4 weeks after receiving...
Read More  |  Review This
Reviews Alendronate Sodium

Fosamax Drug Description FOSAMAX® (alendronate sodium) Tablets and Oral Solution DRUG DESCRIPTION What are the possible side effects of alendronate (Fosamax)? Get emergency medical help if you have any of these signs of an...
Read More  |  Review This
Recent News
59sec - the BEST lead management system around!
We tested 59sec - THE lead management system and we love it. 59sec helps small and medium companies to answer leads in maximum 59 seconds. Why...
MOVEorPAY - our favorite facebook app
We do love MOVEorPAY motivational facebook app, because it is very cool and useful. It makes you finish stuff that you know are good for you, but from various reasons, you never do...
ReviewsAZ is almost ready to be officially launched
yes, we have just a few loose ends to tie and we are ready to go :) meanwhile, I am putting some reviews on the site, so people will not get an empty site at the launch....