Reviews Hycamtin


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Hycamtin Drug Description
HYCAMTIN®
(topotecan hydrochloride) for Injection

WARNING
BONE MARROW SUPPRESSION
Do not give HYCAMTIN to patients with baseline neutrophil counts less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection and death,
monitor peripheral blood counts frequently on all patients receiving HYCAMTIN
[see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of topotecan (Hycamtin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
diarrhea with fever and stomach cramps;
pain or burning when you urinate;
pale skin, easy bruising or bleeding, unusual weakness;


white patches or sores inside your...
Read All Potential Side Effects for Hycamtin »




HYCAMTIN (topotecan hydrochloride) is a semi-synthetic derivative of camptothecin
and is an anti-tumor drug with topoisomerase I-inhibitory activity.
HYCAMTIN for Injection is supplied as a sterile lyophilized, buffered, light
yellow to greenish powder available in single-dose vials. Each vial contains
topotecan hydrochloride equivalent to 4 mg of topotecan as free base. The reconstituted
solution ranges in color from yellow to yellow-green and is intended for administration
by intravenous infusion.
Inactive ingredients are mannitol, 48 mg, and tartaric acid, 20 mg. Hydrochloric
acid and sodium hydroxide may be used to adjust the pH. The solution pH ranges
from 2.5 to 3.5.
The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4
ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione
monohydrochloride. It has the molecular formula C23H23N3O5•HCl and a molecular
weight of 457.9.
Topotecan hydrochloride has the following structural formula:








It is soluble in water and melts with decomposition at 213° to 218°C.
Last reviewed on RxList: 4/16/2010




Hycamtin Drug Description
HYCAMTIN®
(topotecan hydrochloride) for Injection

WARNING
BONE MARROW SUPPRESSION
Do not give HYCAMTIN to patients with baseline neutrophil counts less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection and death,
monitor peripheral blood counts frequently on all patients receiving HYCAMTIN
[see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of topotecan (Hycamtin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
diarrhea with fever and stomach cramps;
pain or burning when you urinate;
pale skin, easy bruising or bleeding, unusual weakness;


white patches or sores inside your...
Read All Potential Side Effects for Hycamtin »




HYCAMTIN (topotecan hydrochloride) is a semi-synthetic derivative of camptothecin
and is an anti-tumor drug with topoisomerase I-inhibitory activity.
HYCAMTIN for Injection is supplied as a sterile lyophilized, buffered, light
yellow to greenish powder available in single-dose vials. Each vial contains
topotecan hydrochloride equivalent to 4 mg of topotecan as free base. The reconstituted
solution ranges in color from yellow to yellow-green and is intended for administration
by intravenous infusion.
Inactive ingredients are mannitol, 48 mg, and tartaric acid, 20 mg. Hydrochloric
acid and sodium hydroxide may be used to adjust the pH. The solution pH ranges
from 2.5 to 3.5.
The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4
ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione
monohydrochloride. It has the molecular formula C23H23N3O5•HCl and a molecular
weight of 457.9.
Topotecan hydrochloride has the following structural formula:








It is soluble in water and melts with decomposition at 213° to 218°C.
Last reviewed on RxList: 4/16/2010




Hycamtin Drug Description
HYCAMTIN®
(topotecan hydrochloride) for Injection

WARNING
BONE MARROW SUPPRESSION
Do not give HYCAMTIN to patients with baseline neutrophil counts less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection and death,
monitor peripheral blood counts frequently on all patients receiving HYCAMTIN
[see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of topotecan (Hycamtin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
diarrhea with fever and stomach cramps;
pain or burning when you urinate;
pale skin, easy bruising or bleeding, unusual weakness;


white patches or sores inside your...
Read All Potential Side Effects for Hycamtin »




HYCAMTIN (topotecan hydrochloride) is a semi-synthetic derivative of camptothecin
and is an anti-tumor drug with topoisomerase I-inhibitory activity.
HYCAMTIN for Injection is supplied as a sterile lyophilized, buffered, light
yellow to greenish powder available in single-dose vials. Each vial contains
topotecan hydrochloride equivalent to 4 mg of topotecan as free base. The reconstituted
solution ranges in color from yellow to yellow-green and is intended for administration
by intravenous infusion.
Inactive ingredients are mannitol, 48 mg, and tartaric acid, 20 mg. Hydrochloric
acid and sodium hydroxide may be used to adjust the pH. The solution pH ranges
from 2.5 to 3.5.
The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4
ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione
monohydrochloride. It has the molecular formula C23H23N3O5•HCl and a molecular
weight of 457.9.
Topotecan hydrochloride has the following structural formula:








It is soluble in water and melts with decomposition at 213° to 218°C.
Last reviewed on RxList: 4/16/2010




Hycamtin Drug Description
HYCAMTIN®
(topotecan hydrochloride) for Injection

WARNING
BONE MARROW SUPPRESSION
Do not give HYCAMTIN to patients with baseline neutrophil counts less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection and death,
monitor peripheral blood counts frequently on all patients receiving HYCAMTIN
[see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of topotecan (Hycamtin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
diarrhea with fever and stomach cramps;
pain or burning when you urinate;
pale skin, easy bruising or bleeding, unusual weakness;


white patches or sores inside your...
Read All Potential Side Effects for Hycamtin »




HYCAMTIN (topotecan hydrochloride) is a semi-synthetic derivative of camptothecin
and is an anti-tumor drug with topoisomerase I-inhibitory activity.
HYCAMTIN for Injection is supplied as a sterile lyophilized, buffered, light
yellow to greenish powder available in single-dose vials. Each vial contains
topotecan hydrochloride equivalent to 4 mg of topotecan as free base. The reconstituted
solution ranges in color from yellow to yellow-green and is intended for administration
by intravenous infusion.
Inactive ingredients are mannitol, 48 mg, and tartaric acid, 20 mg. Hydrochloric
acid and sodium hydroxide may be used to adjust the pH. The solution pH ranges
from 2.5 to 3.5.
The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4
ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione
monohydrochloride. It has the molecular formula C23H23N3O5•HCl and a molecular
weight of 457.9.
Topotecan hydrochloride has the following structural formula:








It is soluble in water and melts with decomposition at 213° to 218°C.
Last reviewed on RxList: 4/16/2010




Hycamtin Drug Description
HYCAMTIN®
(topotecan hydrochloride) for Injection

WARNING
BONE MARROW SUPPRESSION
Do not give HYCAMTIN to patients with baseline neutrophil counts less than
1,500 cells/mm³. In order to monitor the occurrence of bone marrow suppression,
primarily neutropenia, which may be severe and result in infection and death,
monitor peripheral blood counts frequently on all patients receiving HYCAMTIN
[see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of topotecan (Hycamtin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
diarrhea with fever and stomach cramps;
pain or burning when you urinate;
pale skin, easy bruising or bleeding, unusual weakness;


white patches or sores inside your...
Read All Potential Side Effects for Hycamtin »




HYCAMTIN (topotecan hydrochloride) is a semi-synthetic derivative of camptothecin
and is an anti-tumor drug with topoisomerase I-inhibitory activity.
HYCAMTIN for Injection is supplied as a sterile lyophilized, buffered, light
yellow to greenish powder available in single-dose vials. Each vial contains
topotecan hydrochloride equivalent to 4 mg of topotecan as free base. The reconstituted
solution ranges in color from yellow to yellow-green and is intended for administration
by intravenous infusion.
Inactive ingredients are mannitol, 48 mg, and tartaric acid, 20 mg. Hydrochloric
acid and sodium hydroxide may be used to adjust the pH. The solution pH ranges
from 2.5 to 3.5.
The chemical name for topotecan hydrochloride is (S)-10-[(dimethylamino)methyl]-4
ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione
monohydrochloride. It has the molecular formula C23H23N3O5•HCl and a molecular
weight of 457.9.
Topotecan hydrochloride has the following structural formula:








It is soluble in water and melts with decomposition at 213° to 218°C.
Last reviewed on RxList: 4/16/2010





Other reviews about Hycamtin on wordpress

IV HYCAMTIN(R) Receives European Marketing Approval As Treatment For Relapsed Small Cell Lung Cancer
  by rognar
GlaxoSmithKline (GSK) announced that the European Commission (EC) has granted Marketing Authorisation for HYCAMTIN(R) (topotecan powder for concentrate for solution for infusion) for the treatment of patients […]


Hycamtin(R) receives positive opinion in Europe for treatment of patients with relapsed small cell lung cancer
  by rognar
GlaxoSmithKline (GSK) announced that HYCAMTIN(R) (topotecan powder for concentration for solution for infusion) received positive opinion from the European Committee for Human Medicinal Products (CHMP) for the treatment […]


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Access to Investigational Drugs Investigational or experimental drugs are new drugs that have not yet been approved by the FDA or approved drugs that have not yet been approved […]


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  by Pithy
Stated briefly; in general  the treatment of breast cancer in India at present is suboptimal. I was reading a book regarding evolution and changes in management of breast […]


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Voreloxin (at a 48 mg/m² dosage) demonstrates single agent activity in advanced platinum-resistant ovarian cancer patients (24 patients with stable disease (SD) ≥90 days, 1 patent with complete […]


‘Miracle drug’ provides ray of hope in Jade’s desperate fight to stay alive
  by Dream Girl
Hope: Jade is to start a course of ‘miracle drug’ Topotecan which is usually introduced only in cases of advanced cervical cancer Cancer-stricken Jade Goody has been given a […]


WILL THIS HAPPEN IN THEUSA TO CANCER PATIENTS?
  by rotenochsen
Now that we have Obamacare as the law of the land it is appropriate to look at what has happened in England where government controled health care has […]


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  by marketsandmarkets
Original Source: Lung Cancer Drugs Market Buy Now: Lung Oncology Drugs Market INTRODUCTION To define and intensively analyze the Global Non Small Cell Lung Cancer/Oncology […]


Treatment
  by Tikto
Microinvasive cancer (stage IA) is usually treated by hysterectomy (removal of the whole uterus including part of the vagina). For stage IA2, the lymph nodes are removed […]


FDA MedWatch - June 2010 Drug Safety Labeling Changes
  by irbtipoftheweek
The MedWatch June 2010 Drug Safety Labeling Changes posting includes 28 products with safety labeling changes to the following sections: BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, PATIENT […]



Other reviews about Hycamtin on web:

The Products section includes non-promotional information about GSK products, including prescription medicines, consumer healthcare products and vaccines. Hycamtin - Prescription medicines - Our products - GlaxoSmithKline


Learn about the prescription medication Hycamtin (Topotecan Hydrochloride), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Hycamtin (Topotecan Hydrochloride) Drug Information: Uses, Side ...


HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use HYCAMTIN safely and effectively. See full prescribing information for ... HYCAMTIN Injection prescribing information


Topotecan hydrochloride (trade name Hycamtin) is a chemotherapy agent that is a topoisomerase I inhibitor. It is the water-soluble derivative of camptothecin. Topotecan - Wikipedia, the free encyclopedia


All about Hycamtin. View complete and up to date Hycamtin information - part of the Drugs.com trusted medication database. Hycamtin Facts and Comparisons at Drugs.com


Accurate, FDA approved Hycamtin information for healthcare professionals and patients - brought to you by Drugs.com. Hycamtin Official FDA information, side effects and uses.


Learn about the prescription medication Hycamtin Capsules (Topotecan Capsules), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Hycamtin Capsules (Topotecan Capsules) Drug Information: Uses ...


Hycamtin is the trade name for Topotecan. Hycamtin is an anti-cancer chemotherapy drug. This medication is classified as an topoisomerase 1 inhibitor. Hycamtin, Topotecan - Chemotherapy Drugs, Chemo Drug Side Effects


Consumer information about the medication TOPOTECAN - INJECTION (Hycamtin), includes side effects, drug interactions, recommended dosages, and storage information. Read more about ... TOPOTECAN - INJECTION (Hycamtin) side effects, medical uses, and ...


Find patient medical information for Hycamtin IV on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hycamtin IV : Uses, Side Effects, Interactions, Pictures, Warnings ...





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