Reviews Hepsera


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Hepsera Drug Description
HEPSERA
(adefovir dipivoxil) Tablets

WARNING: SEVERE ACUTE EXACERBATIONS OF HEPATITIS, NEPHROTOXICITY, HIV RESISTANCE,
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS
Severe acute exacerbations of hepatitis have been reported in patients who
have discontinued anti-Hepatitis B therapy including HEPSERA. Hepatic function
should be monitored closely with both clinical and laboratory follow-up for
at least several months in patients who discontinue anti-Hepatitis B therapy.
If appropriate, resumption of anti-Hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].
In patients at risk of or having underlying renal dysfunction, chronic
administration of HEPSERA may result in nephrotoxicity. These patients should
be monitored closely for renal function and may require dose adjustment [see
WARNINGS AND PRECAUTIONS and DOSAGE
AND ADMINISTRATION]. HIV resistance may emerge in chronic hepatitis B patients with unrecognized
or untreated Human Immunodeficiency Virus (HIV) infection treated with anti-hepatitis
B therapies, such as therapy with HEPSERA, that may have activity against
HIV [WARNINGS AND PRECAUTIONS].
Lactic acidosis and severe hepatomegaly with steatosis, including fatal
cases, have been reported with the use of nucleoside analogs alone or in combination
with other antiretrovirals [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of adefovir (Hepsera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle pain, tenderness, or weakness (may occur several weeks or months after you start taking adefovir);
numbness or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, fast or...
Read All Potential Side Effects for Hepsera »




HEPSERA® is the tradename for adefovir dipivoxil, a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV).
The chemical name of adefovir dipivoxil is 9-[2-[[bis[(pivaloyloxy)methoxy]-phosphinyl]-methoxy]ethyl]adenine.
It has a molecular formula of C20H32N5O8P,
a molecular weight of 501.48 and the following structural formula:








Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
HEPSERA tablets are for oral administration. Each tablet contains 10 mg of adefovir dipivoxil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized starch, and talc.Last reviewed on RxList: 11/5/2009




Hepsera Drug Description
HEPSERA
(adefovir dipivoxil) Tablets

WARNING: SEVERE ACUTE EXACERBATIONS OF HEPATITIS, NEPHROTOXICITY, HIV RESISTANCE,
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS
Severe acute exacerbations of hepatitis have been reported in patients who
have discontinued anti-Hepatitis B therapy including HEPSERA. Hepatic function
should be monitored closely with both clinical and laboratory follow-up for
at least several months in patients who discontinue anti-Hepatitis B therapy.
If appropriate, resumption of anti-Hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].
In patients at risk of or having underlying renal dysfunction, chronic
administration of HEPSERA may result in nephrotoxicity. These patients should
be monitored closely for renal function and may require dose adjustment [see
WARNINGS AND PRECAUTIONS and DOSAGE
AND ADMINISTRATION]. HIV resistance may emerge in chronic hepatitis B patients with unrecognized
or untreated Human Immunodeficiency Virus (HIV) infection treated with anti-hepatitis
B therapies, such as therapy with HEPSERA, that may have activity against
HIV [WARNINGS AND PRECAUTIONS].
Lactic acidosis and severe hepatomegaly with steatosis, including fatal
cases, have been reported with the use of nucleoside analogs alone or in combination
with other antiretrovirals [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of adefovir (Hepsera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle pain, tenderness, or weakness (may occur several weeks or months after you start taking adefovir);
numbness or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, fast or...
Read All Potential Side Effects for Hepsera »




HEPSERA® is the tradename for adefovir dipivoxil, a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV).
The chemical name of adefovir dipivoxil is 9-[2-[[bis[(pivaloyloxy)methoxy]-phosphinyl]-methoxy]ethyl]adenine.
It has a molecular formula of C20H32N5O8P,
a molecular weight of 501.48 and the following structural formula:








Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
HEPSERA tablets are for oral administration. Each tablet contains 10 mg of adefovir dipivoxil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized starch, and talc.Last reviewed on RxList: 11/5/2009




Hepsera Drug Description
HEPSERA
(adefovir dipivoxil) Tablets

WARNING: SEVERE ACUTE EXACERBATIONS OF HEPATITIS, NEPHROTOXICITY, HIV RESISTANCE,
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS
Severe acute exacerbations of hepatitis have been reported in patients who
have discontinued anti-Hepatitis B therapy including HEPSERA. Hepatic function
should be monitored closely with both clinical and laboratory follow-up for
at least several months in patients who discontinue anti-Hepatitis B therapy.
If appropriate, resumption of anti-Hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].
In patients at risk of or having underlying renal dysfunction, chronic
administration of HEPSERA may result in nephrotoxicity. These patients should
be monitored closely for renal function and may require dose adjustment [see
WARNINGS AND PRECAUTIONS and DOSAGE
AND ADMINISTRATION]. HIV resistance may emerge in chronic hepatitis B patients with unrecognized
or untreated Human Immunodeficiency Virus (HIV) infection treated with anti-hepatitis
B therapies, such as therapy with HEPSERA, that may have activity against
HIV [WARNINGS AND PRECAUTIONS].
Lactic acidosis and severe hepatomegaly with steatosis, including fatal
cases, have been reported with the use of nucleoside analogs alone or in combination
with other antiretrovirals [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of adefovir (Hepsera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle pain, tenderness, or weakness (may occur several weeks or months after you start taking adefovir);
numbness or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, fast or...
Read All Potential Side Effects for Hepsera »




HEPSERA® is the tradename for adefovir dipivoxil, a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV).
The chemical name of adefovir dipivoxil is 9-[2-[[bis[(pivaloyloxy)methoxy]-phosphinyl]-methoxy]ethyl]adenine.
It has a molecular formula of C20H32N5O8P,
a molecular weight of 501.48 and the following structural formula:








Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
HEPSERA tablets are for oral administration. Each tablet contains 10 mg of adefovir dipivoxil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized starch, and talc.Last reviewed on RxList: 11/5/2009




Hepsera Drug Description
HEPSERA
(adefovir dipivoxil) Tablets

WARNING: SEVERE ACUTE EXACERBATIONS OF HEPATITIS, NEPHROTOXICITY, HIV RESISTANCE,
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS
Severe acute exacerbations of hepatitis have been reported in patients who
have discontinued anti-Hepatitis B therapy including HEPSERA. Hepatic function
should be monitored closely with both clinical and laboratory follow-up for
at least several months in patients who discontinue anti-Hepatitis B therapy.
If appropriate, resumption of anti-Hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].
In patients at risk of or having underlying renal dysfunction, chronic
administration of HEPSERA may result in nephrotoxicity. These patients should
be monitored closely for renal function and may require dose adjustment [see
WARNINGS AND PRECAUTIONS and DOSAGE
AND ADMINISTRATION]. HIV resistance may emerge in chronic hepatitis B patients with unrecognized
or untreated Human Immunodeficiency Virus (HIV) infection treated with anti-hepatitis
B therapies, such as therapy with HEPSERA, that may have activity against
HIV [WARNINGS AND PRECAUTIONS].
Lactic acidosis and severe hepatomegaly with steatosis, including fatal
cases, have been reported with the use of nucleoside analogs alone or in combination
with other antiretrovirals [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of adefovir (Hepsera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle pain, tenderness, or weakness (may occur several weeks or months after you start taking adefovir);
numbness or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, fast or...
Read All Potential Side Effects for Hepsera »




HEPSERA® is the tradename for adefovir dipivoxil, a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV).
The chemical name of adefovir dipivoxil is 9-[2-[[bis[(pivaloyloxy)methoxy]-phosphinyl]-methoxy]ethyl]adenine.
It has a molecular formula of C20H32N5O8P,
a molecular weight of 501.48 and the following structural formula:








Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
HEPSERA tablets are for oral administration. Each tablet contains 10 mg of adefovir dipivoxil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized starch, and talc.Last reviewed on RxList: 11/5/2009




Hepsera Drug Description
HEPSERA
(adefovir dipivoxil) Tablets

WARNING: SEVERE ACUTE EXACERBATIONS OF HEPATITIS, NEPHROTOXICITY, HIV RESISTANCE,
LACTIC ACIDOSIS AND SEVERE HEPATOMEGALY WITH STEATOSIS
Severe acute exacerbations of hepatitis have been reported in patients who
have discontinued anti-Hepatitis B therapy including HEPSERA. Hepatic function
should be monitored closely with both clinical and laboratory follow-up for
at least several months in patients who discontinue anti-Hepatitis B therapy.
If appropriate, resumption of anti-Hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].
In patients at risk of or having underlying renal dysfunction, chronic
administration of HEPSERA may result in nephrotoxicity. These patients should
be monitored closely for renal function and may require dose adjustment [see
WARNINGS AND PRECAUTIONS and DOSAGE
AND ADMINISTRATION]. HIV resistance may emerge in chronic hepatitis B patients with unrecognized
or untreated Human Immunodeficiency Virus (HIV) infection treated with anti-hepatitis
B therapies, such as therapy with HEPSERA, that may have activity against
HIV [WARNINGS AND PRECAUTIONS].
Lactic acidosis and severe hepatomegaly with steatosis, including fatal
cases, have been reported with the use of nucleoside analogs alone or in combination
with other antiretrovirals [see WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of adefovir (Hepsera)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle pain, tenderness, or weakness (may occur several weeks or months after you start taking adefovir);
numbness or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, fast or...
Read All Potential Side Effects for Hepsera »




HEPSERA® is the tradename for adefovir dipivoxil, a diester prodrug of adefovir. Adefovir is an acyclic nucleotide analog with activity against human hepatitis B virus (HBV).
The chemical name of adefovir dipivoxil is 9-[2-[[bis[(pivaloyloxy)methoxy]-phosphinyl]-methoxy]ethyl]adenine.
It has a molecular formula of C20H32N5O8P,
a molecular weight of 501.48 and the following structural formula:








Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
HEPSERA tablets are for oral administration. Each tablet contains 10 mg of adefovir dipivoxil and the following inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized starch, and talc.Last reviewed on RxList: 11/5/2009





Other reviews about Hepsera on wordpress

Original Article -Variant of Hepatitis B Virus with Primary Resistance to Adefovir
  by JOC
Source: N Engl J Med 27 Apr 2006 vol.354 N.17 p.1807-1812 Brief Report Oliver Schildgen, Ph.D., Hueseyin Sirma, M.D., Anneke Funk, Ph.D., Cynthia Olotu, M.S., Ulrike C. Wend, Heinz […]


Adefovir, Hepsera
  by hijadoo
U.S. BRAND NAMES — Hepseraâ„¢PHARMACOLOGIC CATEGORY Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)DOSING: ADULTS — Hepatitis B (chronic): Oral: 10 mg once dailyDOSING: ELDERLY — Refer to adult dosing.DOSING: […]


Tin Tức - News: Health Outreach Balances Challenges and Rewards
  by BPSOS
October 7, 2008: Alexia Dinh, program coordinator for BPSOS' Health Awareness and Prevention Program (HAPP), shares the wisdom gained with experience doing outreach around health issues in the […]


Hepatitis B [part 2]
  by pupumomo
Hepatitis B is one of the diseases that are dangerous world, this disease is caused by Hepatitis B virus (VHB), which attacks the liver and cause acute liver […]


Pharmaceutical giants eye China's booming market
  by infoseekchina
Source: (China Daily/Agencies)   China's ambitious $124-billion effort to provide basic health coverage for the vast majority of its 1.3 billion citizens by 2011 is a brimming opportunity for global […]


Gilead Sciences and GlaxoSmithKline enter licensing agreement for hepatitis B treatment
  by silico
On November 24 2009 Gilead Sciences Inc and GlaxoSmithKline entered a licensing agreement to commercialise Viread(R) (tenofovir disoproxil fumarate) for the treatment of chronic hepatitis B (HBV) infection […]


GlaxoSmithKline - Business
  by El Horror
About - Sales: £24.3 billion in 2008; £22.7 billion in 2007; £23.2 billion in 2006; £21.7 billion in 2005. - Profit: £7.8 billion in 2008, 2007, 2006; £6.7 billion in […]


Forecast Insight: Hepatitis B - Baraclude and Viread set to thrive in the face of limited competition now available at ReportsandReports
  by reportsnreports
Dallas, TX: ReportsandReports announce it will carry  Forecast Insight: Hepatitis B - Baraclude and Viread set to thrive in the face of limited competition Market Research […]


Vision Shopsters: Forecast Insight: Hepatitis B - Baraclude and Viread set to thrive in the face of limited competition
  by visionshopsters
Introduction In 2009, hepatitis B sales across the seven major markets totalled $954m, demonstrating a CAGR of 37.5% between 2005 and 2009. Datamonitor expects […]


ReportsandReports - Forecast Insight: Hepatitis B - Baraclude and Viread set to thrive in the face of limited competition
  by reportsnreports
Browse the complete Report Forecast Insight: Hepatitis B - Baraclude and Viread set to thrive in the face of limited competition Browse All Datamonitor Research Reports […]



Other reviews about Hepsera on web:

Discusses the antiviral drug Hepsera (adefovir dipivoxil), from Gilead Sciences. Hepsera


Learn about the prescription medication Hepsera (Adefovir Dipivoxil), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Hepsera (Adefovir Dipivoxil) Drug Information: Uses, Side Effects ...


Accurate, FDA approved Hepsera information for healthcare professionals and patients - brought to you by Drugs.com. Hepsera Official FDA information, side effects and uses.


Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). Adefovir - Wikipedia, the free encyclopedia


All about Hepsera. View complete and up to date Hepsera information - part of the Drugs.com trusted medication database. Hepsera Facts and Comparisons at Drugs.com


Up-to-date HIV and AIDS and Hepatitis treatment and care information Hepsera (Adefovir Dipivoxil)


Hepsera is a nucleotide analog used to treat chronic hepatitis B virus (HBV) infection. Side effects and interactions are available at drugstore.com; plus get home delivery from a ... Hepsera - drugstore.com. Low prices, side effects, interactions.


Hepsera, approved by the FDA last September, is as effective as the two standard therapies now used to treat chronic hepatitis B virus infections. New Hepatitis B Drug Hepsera Better Than Current Treatment


Find patient medical information for Hepsera Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hepsera Oral : Uses, Side Effects, Interactions, Pictures ...


Find lowest price for a Hepsera prescription. Save up to 70% on drug prices at verified online pharmacies. Buy Hepsera Online | Compare Hepsera Prices & Save - Pharmahelper.com





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