Reviews Hepatitis B Vaccine


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Recombivax Drug Description
RECOMBIVAX HB®
Hepatitis B Vaccine (Recombinant)
DRUG DESCRIPTION



What are the possible side effects of this vaccine (Engerix-B, Engerix-B Pediatric, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent)?

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with hepatitis B is much more dangerous to your health than...
Read All Potential Side Effects for Recombivax »




RECOMBIVAX HB* Hepatitis B Vaccine (Recombinant) is a non-infectious subunit
viral vaccine derived from hepatitis B surface antigen (HBsAg) produced in yeast
cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned
into yeast, and the vaccine for hepatitis B is produced from cultures of this
recombinant yeast strain according to methods developed in the Merck Research
Laboratories.
The antigen is harvested and purified from fermentation cultures of a recombinant
strain of the yeast Saccharomyces cerevisiae containing the gene for
the adw subtype of HBsAg. The fermentation process involves growth of
Saccharomyces cerevisiae on a complex fermentation medium which consists
of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.
The HBsAg protein is released from the yeast cells by cell disruption and purified
by a series of physical and chemical methods. The purified protein is treated
in phosphate buffer with formaldehyde and then coprecipitated with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate
sulfate. The vaccine contains no detectable yeast DNA but may contain not more
than 1% yeast protein. The vaccine produced by the Merck method has been shown
to be comparable to the plasma-derived vaccine in terms of animal potency (mouse,
monkey, and chimpanzee) and protective efficacy (chimpanzee and human).
The vaccine against hepatitis B, prepared from recombinant yeast cultures,
is free of association with human blood or blood products.
Each lot of hepatitis B vaccine is tested for sterility.
RECOMBIVAX HB is a sterile suspension for intramuscular injection. However,
for persons at risk of hemorrhage following intramuscular injection, the vaccine
may be administered subcutaneously. (See DOSAGE AND ADMINISTRATION).
RECOMBIVAX HB Hepatitis B Vaccine (Recombinant) is supplied in three formulations.
(See HOW SUPPLIED.)
Pediatric/Adolescent Formulation (Without Preservative), 10 mcg/mL:
each 0.5 mL dose contains 5 mcg of hepatitis B surface antigen.
Adult Formulation (Without Preservative), 10 mcg/mL: each 1 mL dose
contains 10 mcg of hepatitis B surface antigen.
Dialysis Formulation (Without Preservative), 40 mcg/mL: each 1 mL dose
contains 40 mcg of hepatitis B surface antigen.
All formulations contain approximately 0.5 mg of aluminum (provided as amorphous
aluminum hydroxyphosphate sulfate, previously referred to as aluminum hydroxide)
per mL of vaccine. In each formulation, hepatitis B surface antigen is adsorbed
onto approximately 0.5 mg of aluminum (provided as amorphous aluminum hydroxyphosphate
sulfate) per mL of vaccine. The vaccine is of the adw subtype. RECOMBIVAX
HB is indicated for vaccination of persons at risk of infection from hepatitis
B virus including all known subtypes. RECOMBIVAX HB Dialysis Formulation is
indicated for vaccination of adult predialysis and dialysis patients against
infection caused by all known subtypes of hepatitis B virus.
* Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998 MERCK
& CO., Inc. All rights reserved
Last reviewed on RxList: 9/2/2008




Recombivax Drug Description
RECOMBIVAX HB®
Hepatitis B Vaccine (Recombinant)
DRUG DESCRIPTION



What are the possible side effects of this vaccine (Engerix-B, Engerix-B Pediatric, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent)?

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with hepatitis B is much more dangerous to your health than...
Read All Potential Side Effects for Recombivax »




RECOMBIVAX HB* Hepatitis B Vaccine (Recombinant) is a non-infectious subunit
viral vaccine derived from hepatitis B surface antigen (HBsAg) produced in yeast
cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned
into yeast, and the vaccine for hepatitis B is produced from cultures of this
recombinant yeast strain according to methods developed in the Merck Research
Laboratories.
The antigen is harvested and purified from fermentation cultures of a recombinant
strain of the yeast Saccharomyces cerevisiae containing the gene for
the adw subtype of HBsAg. The fermentation process involves growth of
Saccharomyces cerevisiae on a complex fermentation medium which consists
of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.
The HBsAg protein is released from the yeast cells by cell disruption and purified
by a series of physical and chemical methods. The purified protein is treated
in phosphate buffer with formaldehyde and then coprecipitated with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate
sulfate. The vaccine contains no detectable yeast DNA but may contain not more
than 1% yeast protein. The vaccine produced by the Merck method has been shown
to be comparable to the plasma-derived vaccine in terms of animal potency (mouse,
monkey, and chimpanzee) and protective efficacy (chimpanzee and human).
The vaccine against hepatitis B, prepared from recombinant yeast cultures,
is free of association with human blood or blood products.
Each lot of hepatitis B vaccine is tested for sterility.
RECOMBIVAX HB is a sterile suspension for intramuscular injection. However,
for persons at risk of hemorrhage following intramuscular injection, the vaccine
may be administered subcutaneously. (See DOSAGE AND ADMINISTRATION).
RECOMBIVAX HB Hepatitis B Vaccine (Recombinant) is supplied in three formulations.
(See HOW SUPPLIED.)
Pediatric/Adolescent Formulation (Without Preservative), 10 mcg/mL:
each 0.5 mL dose contains 5 mcg of hepatitis B surface antigen.
Adult Formulation (Without Preservative), 10 mcg/mL: each 1 mL dose
contains 10 mcg of hepatitis B surface antigen.
Dialysis Formulation (Without Preservative), 40 mcg/mL: each 1 mL dose
contains 40 mcg of hepatitis B surface antigen.
All formulations contain approximately 0.5 mg of aluminum (provided as amorphous
aluminum hydroxyphosphate sulfate, previously referred to as aluminum hydroxide)
per mL of vaccine. In each formulation, hepatitis B surface antigen is adsorbed
onto approximately 0.5 mg of aluminum (provided as amorphous aluminum hydroxyphosphate
sulfate) per mL of vaccine. The vaccine is of the adw subtype. RECOMBIVAX
HB is indicated for vaccination of persons at risk of infection from hepatitis
B virus including all known subtypes. RECOMBIVAX HB Dialysis Formulation is
indicated for vaccination of adult predialysis and dialysis patients against
infection caused by all known subtypes of hepatitis B virus.
* Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998 MERCK
& CO., Inc. All rights reserved
Last reviewed on RxList: 9/2/2008




Recombivax Drug Description
RECOMBIVAX HB®
Hepatitis B Vaccine (Recombinant)
DRUG DESCRIPTION



What are the possible side effects of this vaccine (Engerix-B, Engerix-B Pediatric, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent)?

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with hepatitis B is much more dangerous to your health than...
Read All Potential Side Effects for Recombivax »




RECOMBIVAX HB* Hepatitis B Vaccine (Recombinant) is a non-infectious subunit
viral vaccine derived from hepatitis B surface antigen (HBsAg) produced in yeast
cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned
into yeast, and the vaccine for hepatitis B is produced from cultures of this
recombinant yeast strain according to methods developed in the Merck Research
Laboratories.
The antigen is harvested and purified from fermentation cultures of a recombinant
strain of the yeast Saccharomyces cerevisiae containing the gene for
the adw subtype of HBsAg. The fermentation process involves growth of
Saccharomyces cerevisiae on a complex fermentation medium which consists
of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.
The HBsAg protein is released from the yeast cells by cell disruption and purified
by a series of physical and chemical methods. The purified protein is treated
in phosphate buffer with formaldehyde and then coprecipitated with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate
sulfate. The vaccine contains no detectable yeast DNA but may contain not more
than 1% yeast protein. The vaccine produced by the Merck method has been shown
to be comparable to the plasma-derived vaccine in terms of animal potency (mouse,
monkey, and chimpanzee) and protective efficacy (chimpanzee and human).
The vaccine against hepatitis B, prepared from recombinant yeast cultures,
is free of association with human blood or blood products.
Each lot of hepatitis B vaccine is tested for sterility.
RECOMBIVAX HB is a sterile suspension for intramuscular injection. However,
for persons at risk of hemorrhage following intramuscular injection, the vaccine
may be administered subcutaneously. (See DOSAGE AND ADMINISTRATION).
RECOMBIVAX HB Hepatitis B Vaccine (Recombinant) is supplied in three formulations.
(See HOW SUPPLIED.)
Pediatric/Adolescent Formulation (Without Preservative), 10 mcg/mL:
each 0.5 mL dose contains 5 mcg of hepatitis B surface antigen.
Adult Formulation (Without Preservative), 10 mcg/mL: each 1 mL dose
contains 10 mcg of hepatitis B surface antigen.
Dialysis Formulation (Without Preservative), 40 mcg/mL: each 1 mL dose
contains 40 mcg of hepatitis B surface antigen.
All formulations contain approximately 0.5 mg of aluminum (provided as amorphous
aluminum hydroxyphosphate sulfate, previously referred to as aluminum hydroxide)
per mL of vaccine. In each formulation, hepatitis B surface antigen is adsorbed
onto approximately 0.5 mg of aluminum (provided as amorphous aluminum hydroxyphosphate
sulfate) per mL of vaccine. The vaccine is of the adw subtype. RECOMBIVAX
HB is indicated for vaccination of persons at risk of infection from hepatitis
B virus including all known subtypes. RECOMBIVAX HB Dialysis Formulation is
indicated for vaccination of adult predialysis and dialysis patients against
infection caused by all known subtypes of hepatitis B virus.
* Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998 MERCK
& CO., Inc. All rights reserved
Last reviewed on RxList: 9/2/2008




Recombivax Drug Description
RECOMBIVAX HB®
Hepatitis B Vaccine (Recombinant)
DRUG DESCRIPTION



What are the possible side effects of this vaccine (Engerix-B, Engerix-B Pediatric, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent)?

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with hepatitis B is much more dangerous to your health than...
Read All Potential Side Effects for Recombivax »




RECOMBIVAX HB* Hepatitis B Vaccine (Recombinant) is a non-infectious subunit
viral vaccine derived from hepatitis B surface antigen (HBsAg) produced in yeast
cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned
into yeast, and the vaccine for hepatitis B is produced from cultures of this
recombinant yeast strain according to methods developed in the Merck Research
Laboratories.
The antigen is harvested and purified from fermentation cultures of a recombinant
strain of the yeast Saccharomyces cerevisiae containing the gene for
the adw subtype of HBsAg. The fermentation process involves growth of
Saccharomyces cerevisiae on a complex fermentation medium which consists
of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.
The HBsAg protein is released from the yeast cells by cell disruption and purified
by a series of physical and chemical methods. The purified protein is treated
in phosphate buffer with formaldehyde and then coprecipitated with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate
sulfate. The vaccine contains no detectable yeast DNA but may contain not more
than 1% yeast protein. The vaccine produced by the Merck method has been shown
to be comparable to the plasma-derived vaccine in terms of animal potency (mouse,
monkey, and chimpanzee) and protective efficacy (chimpanzee and human).
The vaccine against hepatitis B, prepared from recombinant yeast cultures,
is free of association with human blood or blood products.
Each lot of hepatitis B vaccine is tested for sterility.
RECOMBIVAX HB is a sterile suspension for intramuscular injection. However,
for persons at risk of hemorrhage following intramuscular injection, the vaccine
may be administered subcutaneously. (See DOSAGE AND ADMINISTRATION).
RECOMBIVAX HB Hepatitis B Vaccine (Recombinant) is supplied in three formulations.
(See HOW SUPPLIED.)
Pediatric/Adolescent Formulation (Without Preservative), 10 mcg/mL:
each 0.5 mL dose contains 5 mcg of hepatitis B surface antigen.
Adult Formulation (Without Preservative), 10 mcg/mL: each 1 mL dose
contains 10 mcg of hepatitis B surface antigen.
Dialysis Formulation (Without Preservative), 40 mcg/mL: each 1 mL dose
contains 40 mcg of hepatitis B surface antigen.
All formulations contain approximately 0.5 mg of aluminum (provided as amorphous
aluminum hydroxyphosphate sulfate, previously referred to as aluminum hydroxide)
per mL of vaccine. In each formulation, hepatitis B surface antigen is adsorbed
onto approximately 0.5 mg of aluminum (provided as amorphous aluminum hydroxyphosphate
sulfate) per mL of vaccine. The vaccine is of the adw subtype. RECOMBIVAX
HB is indicated for vaccination of persons at risk of infection from hepatitis
B virus including all known subtypes. RECOMBIVAX HB Dialysis Formulation is
indicated for vaccination of adult predialysis and dialysis patients against
infection caused by all known subtypes of hepatitis B virus.
* Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998 MERCK
& CO., Inc. All rights reserved
Last reviewed on RxList: 9/2/2008




Recombivax Drug Description
RECOMBIVAX HB®
Hepatitis B Vaccine (Recombinant)
DRUG DESCRIPTION



What are the possible side effects of this vaccine (Engerix-B, Engerix-B Pediatric, Recombivax HB Adult, Recombivax HB Dialysis Formulation, Recombivax HB Pediatric/Adolescent)?

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with hepatitis B is much more dangerous to your health than...
Read All Potential Side Effects for Recombivax »




RECOMBIVAX HB* Hepatitis B Vaccine (Recombinant) is a non-infectious subunit
viral vaccine derived from hepatitis B surface antigen (HBsAg) produced in yeast
cells. A portion of the hepatitis B virus gene, coding for HBsAg, is cloned
into yeast, and the vaccine for hepatitis B is produced from cultures of this
recombinant yeast strain according to methods developed in the Merck Research
Laboratories.
The antigen is harvested and purified from fermentation cultures of a recombinant
strain of the yeast Saccharomyces cerevisiae containing the gene for
the adw subtype of HBsAg. The fermentation process involves growth of
Saccharomyces cerevisiae on a complex fermentation medium which consists
of an extract of yeast, soy peptone, dextrose, amino acids and mineral salts.
The HBsAg protein is released from the yeast cells by cell disruption and purified
by a series of physical and chemical methods. The purified protein is treated
in phosphate buffer with formaldehyde and then coprecipitated with alum (potassium aluminum sulfate) to form bulk vaccine adjuvanted with amorphous aluminum hydroxyphosphate
sulfate. The vaccine contains no detectable yeast DNA but may contain not more
than 1% yeast protein. The vaccine produced by the Merck method has been shown
to be comparable to the plasma-derived vaccine in terms of animal potency (mouse,
monkey, and chimpanzee) and protective efficacy (chimpanzee and human).
The vaccine against hepatitis B, prepared from recombinant yeast cultures,
is free of association with human blood or blood products.
Each lot of hepatitis B vaccine is tested for sterility.
RECOMBIVAX HB is a sterile suspension for intramuscular injection. However,
for persons at risk of hemorrhage following intramuscular injection, the vaccine
may be administered subcutaneously. (See DOSAGE AND ADMINISTRATION).
RECOMBIVAX HB Hepatitis B Vaccine (Recombinant) is supplied in three formulations.
(See HOW SUPPLIED.)
Pediatric/Adolescent Formulation (Without Preservative), 10 mcg/mL:
each 0.5 mL dose contains 5 mcg of hepatitis B surface antigen.
Adult Formulation (Without Preservative), 10 mcg/mL: each 1 mL dose
contains 10 mcg of hepatitis B surface antigen.
Dialysis Formulation (Without Preservative), 40 mcg/mL: each 1 mL dose
contains 40 mcg of hepatitis B surface antigen.
All formulations contain approximately 0.5 mg of aluminum (provided as amorphous
aluminum hydroxyphosphate sulfate, previously referred to as aluminum hydroxide)
per mL of vaccine. In each formulation, hepatitis B surface antigen is adsorbed
onto approximately 0.5 mg of aluminum (provided as amorphous aluminum hydroxyphosphate
sulfate) per mL of vaccine. The vaccine is of the adw subtype. RECOMBIVAX
HB is indicated for vaccination of persons at risk of infection from hepatitis
B virus including all known subtypes. RECOMBIVAX HB Dialysis Formulation is
indicated for vaccination of adult predialysis and dialysis patients against
infection caused by all known subtypes of hepatitis B virus.
* Registered trademark of MERCK & CO., Inc. COPYRIGHT © 1998 MERCK
& CO., Inc. All rights reserved
Last reviewed on RxList: 9/2/2008





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Other reviews about Hepatitis B Vaccine on web:

Hepatitis B vaccine is a vaccine developed for the prevention of hepatitis B virus infection. The vaccine contains one of the viral envelope proteins, hepatitis B surface ... Hepatitis B vaccine - Wikipedia, the free encyclopedia


From the Immunization Action Coalition Vaccine Information for the public and health professionals Vaccine Information about Hepatitis B


HEPATITIS B VACCINE W H AT YO U N E E D T O K N O W Many Vaccine Information Statements are available in Spanish and other languages. See www.immunize.org/vis. 1 What is ... Hepatitis B Vaccine - What you need to know- 508 compliant.


Hepatitis B Vaccine, Recombinant Brand names: Engerix-B®Engerix-B® PediatricH-B-Vax™RDNA H B Vax II™Recombivax HB® Drug hepatitis B vaccine: Definition from Answers.com


Hepatitis B vaccine info for parents, public, and healthcare professionals Vaccines: VPD-VAC/HepB/main page


From the Immunization Action Coalition Vaccine Information for the public and health professionals Hepatitis B Vaccine Questions and Answers


HepB Vaccine Information: It takes only 3 shots to protect yourself and your loved ones against hepatitis B for a lifetime. Hepatitis B Vaccine Information from Hepatitis B Foundation:


Hepatitis B Vaccine professional patient advice. Specific and up to date information about Hepatitis B Vaccine. Complete Hepatitis B Vaccine information from Drugs.com


The hepatitis B vaccine has been linked to neurological disorders, multiple sclerosis, and death. In spite of medical denials, research indicates a likely connection. Hepatitis B Vaccines: Adverse Reactions. Thinktwice!


The hepatitis B vaccine protects against hepatitis B, a serious disease that damages the liver. The vaccine is one of the recommended childhood immunizations. Hepatitis B vaccine: MedlinePlus Medical Encyclopedia





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