Reviews Goserelin Acetate Implant


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Zoladex 10.8 mg Drug Description
ZOLADEX® 10.8 mg 3-Month Depot
(goserelin acetate) Implant
FOR USE IN MEN WITH PROSTATE CANCER
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 10.8 mg »




ZOLADEX® (goserelin acetate implant), contains a potent synthetic decapeptide
analogue of luteinizing hormone-releasing hormone (LHRH), also known as a gonadotropin
releasing hormone (GnRH) agonist analogue. Goserelin acetate is chemically described
as an acetate salt of [D-Ser(But)6,Azgly10]LHRH.
Its chemical structure is pyro-Glu-His-Trp-Ser-Tyr-D-Ser(But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)x
where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular weight of 1269 Daltons
(free base). It is freely soluble in glacial acetic acid. It is soluble in water,
0.1M hydrochloric acid, 0.1M sodium hydroxide, dimethylformamide and dimethyl
sulfoxide. Goserelin acetate is practically insoluble in acetone, chloroform
and ether.
ZOLADEX 10.8 mg implant is supplied as a sterile, biodegradable product containing
goserelin acetate equivalent to 10.8 mg of goserelin. ZOLADEX is designed for
subcutaneous implantation with continuous release over a 12-week period. Goserelin
acetate is dispersed in a matrix of D,L-lactic and glycolic acids copolymer
(12.82-14.76 mg/dose) containing less than 2% acetic acid and up to 10% goserelin-related
substances and presented as a sterile, white to cream colored 1.5 mm diameter
cylinder, preloaded in a special single-use syringe with a 14-gauge x 36 +/-
0.5 mm siliconized needle with protective needle sleeve (SafeSystem™ Syringe)
in a sealed, light- and moisture-proof, aluminum foil laminate pouch containing
a desiccant capsule.
Studies of the D,L-lactic and glycolic acids copolymer have indicated that
it is completely biodegradable and has no demonstrable antigenic potential.

ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin
acetate equivalent to 3.6 mg of goserelin designed for administration every
28 days.Last reviewed on RxList: 3/5/2009




Zoladex 10.8 mg Drug Description
ZOLADEX® 10.8 mg 3-Month Depot
(goserelin acetate) Implant
FOR USE IN MEN WITH PROSTATE CANCER
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 10.8 mg »




ZOLADEX® (goserelin acetate implant), contains a potent synthetic decapeptide
analogue of luteinizing hormone-releasing hormone (LHRH), also known as a gonadotropin
releasing hormone (GnRH) agonist analogue. Goserelin acetate is chemically described
as an acetate salt of [D-Ser(But)6,Azgly10]LHRH.
Its chemical structure is pyro-Glu-His-Trp-Ser-Tyr-D-Ser(But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)x
where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular weight of 1269 Daltons
(free base). It is freely soluble in glacial acetic acid. It is soluble in water,
0.1M hydrochloric acid, 0.1M sodium hydroxide, dimethylformamide and dimethyl
sulfoxide. Goserelin acetate is practically insoluble in acetone, chloroform
and ether.
ZOLADEX 10.8 mg implant is supplied as a sterile, biodegradable product containing
goserelin acetate equivalent to 10.8 mg of goserelin. ZOLADEX is designed for
subcutaneous implantation with continuous release over a 12-week period. Goserelin
acetate is dispersed in a matrix of D,L-lactic and glycolic acids copolymer
(12.82-14.76 mg/dose) containing less than 2% acetic acid and up to 10% goserelin-related
substances and presented as a sterile, white to cream colored 1.5 mm diameter
cylinder, preloaded in a special single-use syringe with a 14-gauge x 36 +/-
0.5 mm siliconized needle with protective needle sleeve (SafeSystem™ Syringe)
in a sealed, light- and moisture-proof, aluminum foil laminate pouch containing
a desiccant capsule.
Studies of the D,L-lactic and glycolic acids copolymer have indicated that
it is completely biodegradable and has no demonstrable antigenic potential.

ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin
acetate equivalent to 3.6 mg of goserelin designed for administration every
28 days.Last reviewed on RxList: 3/5/2009




Zoladex 10.8 mg Drug Description
ZOLADEX® 10.8 mg 3-Month Depot
(goserelin acetate) Implant
FOR USE IN MEN WITH PROSTATE CANCER
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 10.8 mg »




ZOLADEX® (goserelin acetate implant), contains a potent synthetic decapeptide
analogue of luteinizing hormone-releasing hormone (LHRH), also known as a gonadotropin
releasing hormone (GnRH) agonist analogue. Goserelin acetate is chemically described
as an acetate salt of [D-Ser(But)6,Azgly10]LHRH.
Its chemical structure is pyro-Glu-His-Trp-Ser-Tyr-D-Ser(But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)x
where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular weight of 1269 Daltons
(free base). It is freely soluble in glacial acetic acid. It is soluble in water,
0.1M hydrochloric acid, 0.1M sodium hydroxide, dimethylformamide and dimethyl
sulfoxide. Goserelin acetate is practically insoluble in acetone, chloroform
and ether.
ZOLADEX 10.8 mg implant is supplied as a sterile, biodegradable product containing
goserelin acetate equivalent to 10.8 mg of goserelin. ZOLADEX is designed for
subcutaneous implantation with continuous release over a 12-week period. Goserelin
acetate is dispersed in a matrix of D,L-lactic and glycolic acids copolymer
(12.82-14.76 mg/dose) containing less than 2% acetic acid and up to 10% goserelin-related
substances and presented as a sterile, white to cream colored 1.5 mm diameter
cylinder, preloaded in a special single-use syringe with a 14-gauge x 36 +/-
0.5 mm siliconized needle with protective needle sleeve (SafeSystem™ Syringe)
in a sealed, light- and moisture-proof, aluminum foil laminate pouch containing
a desiccant capsule.
Studies of the D,L-lactic and glycolic acids copolymer have indicated that
it is completely biodegradable and has no demonstrable antigenic potential.

ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin
acetate equivalent to 3.6 mg of goserelin designed for administration every
28 days.Last reviewed on RxList: 3/5/2009




Zoladex 10.8 mg Drug Description
ZOLADEX® 10.8 mg 3-Month Depot
(goserelin acetate) Implant
FOR USE IN MEN WITH PROSTATE CANCER
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 10.8 mg »




ZOLADEX® (goserelin acetate implant), contains a potent synthetic decapeptide
analogue of luteinizing hormone-releasing hormone (LHRH), also known as a gonadotropin
releasing hormone (GnRH) agonist analogue. Goserelin acetate is chemically described
as an acetate salt of [D-Ser(But)6,Azgly10]LHRH.
Its chemical structure is pyro-Glu-His-Trp-Ser-Tyr-D-Ser(But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)x
where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular weight of 1269 Daltons
(free base). It is freely soluble in glacial acetic acid. It is soluble in water,
0.1M hydrochloric acid, 0.1M sodium hydroxide, dimethylformamide and dimethyl
sulfoxide. Goserelin acetate is practically insoluble in acetone, chloroform
and ether.
ZOLADEX 10.8 mg implant is supplied as a sterile, biodegradable product containing
goserelin acetate equivalent to 10.8 mg of goserelin. ZOLADEX is designed for
subcutaneous implantation with continuous release over a 12-week period. Goserelin
acetate is dispersed in a matrix of D,L-lactic and glycolic acids copolymer
(12.82-14.76 mg/dose) containing less than 2% acetic acid and up to 10% goserelin-related
substances and presented as a sterile, white to cream colored 1.5 mm diameter
cylinder, preloaded in a special single-use syringe with a 14-gauge x 36 +/-
0.5 mm siliconized needle with protective needle sleeve (SafeSystem™ Syringe)
in a sealed, light- and moisture-proof, aluminum foil laminate pouch containing
a desiccant capsule.
Studies of the D,L-lactic and glycolic acids copolymer have indicated that
it is completely biodegradable and has no demonstrable antigenic potential.

ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin
acetate equivalent to 3.6 mg of goserelin designed for administration every
28 days.Last reviewed on RxList: 3/5/2009




Zoladex 10.8 mg Drug Description
ZOLADEX® 10.8 mg 3-Month Depot
(goserelin acetate) Implant
FOR USE IN MEN WITH PROSTATE CANCER
DRUG DESCRIPTION



What are the possible side effects of goserelin (Zoladex)?

Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if...
Read All Potential Side Effects for Zoladex 10.8 mg »




ZOLADEX® (goserelin acetate implant), contains a potent synthetic decapeptide
analogue of luteinizing hormone-releasing hormone (LHRH), also known as a gonadotropin
releasing hormone (GnRH) agonist analogue. Goserelin acetate is chemically described
as an acetate salt of [D-Ser(But)6,Azgly10]LHRH.
Its chemical structure is pyro-Glu-His-Trp-Ser-Tyr-D-Ser(But)-Leu-Arg-Pro-Azgly-NH2
acetate [C59H84N18O14 • (C2H4O2)x
where x = 1 to 2.4].
Goserelin acetate is an off-white powder with a molecular weight of 1269 Daltons
(free base). It is freely soluble in glacial acetic acid. It is soluble in water,
0.1M hydrochloric acid, 0.1M sodium hydroxide, dimethylformamide and dimethyl
sulfoxide. Goserelin acetate is practically insoluble in acetone, chloroform
and ether.
ZOLADEX 10.8 mg implant is supplied as a sterile, biodegradable product containing
goserelin acetate equivalent to 10.8 mg of goserelin. ZOLADEX is designed for
subcutaneous implantation with continuous release over a 12-week period. Goserelin
acetate is dispersed in a matrix of D,L-lactic and glycolic acids copolymer
(12.82-14.76 mg/dose) containing less than 2% acetic acid and up to 10% goserelin-related
substances and presented as a sterile, white to cream colored 1.5 mm diameter
cylinder, preloaded in a special single-use syringe with a 14-gauge x 36 +/-
0.5 mm siliconized needle with protective needle sleeve (SafeSystem™ Syringe)
in a sealed, light- and moisture-proof, aluminum foil laminate pouch containing
a desiccant capsule.
Studies of the D,L-lactic and glycolic acids copolymer have indicated that
it is completely biodegradable and has no demonstrable antigenic potential.

ZOLADEX is also supplied as a sterile, biodegradable product containing goserelin
acetate equivalent to 3.6 mg of goserelin designed for administration every
28 days.Last reviewed on RxList: 3/5/2009





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Other reviews about Goserelin Acetate Implant on web:

Goserelin acetate (Zoladex, AstraZeneca) is an injectable gonadotropin releasing hormone super ... 10.8mg implant syringe Goserelin - Wikipedia, the free encyclopedia


Goserelin Acetate Implant To return to the main entry click here . What is this medicine? GOSERELIN (GOE se rel in) is similar to a hormone found in Goserelin Acetate Implant: Information from Answers.com


Learn about the prescription medication Zoladex 10.8 mg (Goserelin Acetate Implant), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Zoladex 10.8 mg (Goserelin Acetate Implant) Drug Information: Uses ...


ZOLADEX ® (goserelin acetate implant) 3.6 mg Initial U.S. Approval: 1989-----RECENT MAJOR CHANGES-----Warnings and Precautions ... ZOLADEX


The new formation, 10.8 mg goserelin acetate implant given every three months, offers greater convenience to subjects choosing treatment with a luteinizing-hormone-releasing ... Newly Approved Drug Therapies (38) Zoladex (10.8 mg goserelin ...


DICP, The Annals of Pharmacotherapy: Vol. 25, No. 7, pp. 796-804. © 1991 Harvey Whitney Books Company. Goserelin acetate implant: a depot luteinizing hormone-releasing ...


1 Rev 12/03 SIC 64216-00 ZOLADEX (goserelin acetate implant) 3.6 MG Equivalent to 3.6 mg goserelin DESCRIPTION ZOLADEX® (goserelin acetate implant), contains a potent ... (goserelin acetate implant) 3.6 MG


Zoladex (goserelin acetate) implant Drug Safety Labeling Changes August 2009 -MedWatch Zoladex (goserelin acetate) implant


ZOLADEX ® (goserelin acetate implant) 10.8 mg Initial U.S. Approval: 1996-----RECENT MAJOR CHANGES-----Warnings and Precautions ... To report SUSPECTED ADVERSE REACTIONS, contact AstraZeneca at 1 ...


Goserelin Acetate Implant What is this medicine? GOSERELIN (GOE se rel in) is similar to a hormone found in the body. It lowers the amount of sex hormones that the body makes. Goserelin





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