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Gliadel Drug Description
GLIADEL® WAFER
(polifeprosan 20 with carmustine) Implant
DRUG DESCRIPTION
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is a sterile, off-white to pale yellow wafer approximately 1.45 cm in diameter and 1 mm thick. Each wafer contains 192.3 mg of a biodegradable polyanhydride copolymer and 7.7 mg of carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea, or BCNU]. Carmustine is a nitrosourea oncolytic agent. The copolymer, polifeprosan 20, consists of poly[bis(p-carboxyphenoxy) propane: sebacic acid] in a 20:80 molar ratio and is used to control the local delivery of carmustine. Carmustine is homogeneously distributed in the copolymer matrix.
The structural formula for polifeprosan 20 is:








The structural formula for carmustine is:







Last reviewed on RxList: 3/6/2009




Gliadel Drug Description
GLIADEL® WAFER
(polifeprosan 20 with carmustine) Implant
DRUG DESCRIPTION
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is a sterile, off-white to pale yellow wafer approximately 1.45 cm in diameter and 1 mm thick. Each wafer contains 192.3 mg of a biodegradable polyanhydride copolymer and 7.7 mg of carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea, or BCNU]. Carmustine is a nitrosourea oncolytic agent. The copolymer, polifeprosan 20, consists of poly[bis(p-carboxyphenoxy) propane: sebacic acid] in a 20:80 molar ratio and is used to control the local delivery of carmustine. Carmustine is homogeneously distributed in the copolymer matrix.
The structural formula for polifeprosan 20 is:








The structural formula for carmustine is:







Last reviewed on RxList: 3/6/2009




Gliadel Drug Description
GLIADEL® WAFER
(polifeprosan 20 with carmustine) Implant
DRUG DESCRIPTION
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is a sterile, off-white to pale yellow wafer approximately 1.45 cm in diameter and 1 mm thick. Each wafer contains 192.3 mg of a biodegradable polyanhydride copolymer and 7.7 mg of carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea, or BCNU]. Carmustine is a nitrosourea oncolytic agent. The copolymer, polifeprosan 20, consists of poly[bis(p-carboxyphenoxy) propane: sebacic acid] in a 20:80 molar ratio and is used to control the local delivery of carmustine. Carmustine is homogeneously distributed in the copolymer matrix.
The structural formula for polifeprosan 20 is:








The structural formula for carmustine is:







Last reviewed on RxList: 3/6/2009




Gliadel Drug Description
GLIADEL® WAFER
(polifeprosan 20 with carmustine) Implant
DRUG DESCRIPTION
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is a sterile, off-white to pale yellow wafer approximately 1.45 cm in diameter and 1 mm thick. Each wafer contains 192.3 mg of a biodegradable polyanhydride copolymer and 7.7 mg of carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea, or BCNU]. Carmustine is a nitrosourea oncolytic agent. The copolymer, polifeprosan 20, consists of poly[bis(p-carboxyphenoxy) propane: sebacic acid] in a 20:80 molar ratio and is used to control the local delivery of carmustine. Carmustine is homogeneously distributed in the copolymer matrix.
The structural formula for polifeprosan 20 is:








The structural formula for carmustine is:







Last reviewed on RxList: 3/6/2009




Gliadel Drug Description
GLIADEL® WAFER
(polifeprosan 20 with carmustine) Implant
DRUG DESCRIPTION
GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is a sterile, off-white to pale yellow wafer approximately 1.45 cm in diameter and 1 mm thick. Each wafer contains 192.3 mg of a biodegradable polyanhydride copolymer and 7.7 mg of carmustine [1,3-bis (2-chloroethyl)-1-nitrosourea, or BCNU]. Carmustine is a nitrosourea oncolytic agent. The copolymer, polifeprosan 20, consists of poly[bis(p-carboxyphenoxy) propane: sebacic acid] in a 20:80 molar ratio and is used to control the local delivery of carmustine. Carmustine is homogeneously distributed in the copolymer matrix.
The structural formula for polifeprosan 20 is:








The structural formula for carmustine is:







Last reviewed on RxList: 3/6/2009





Other reviews about Gliadel on wordpress

Brain cancer treatment assigned new DRG
  by biomedne
Now Medicare patients with brain cancer will be able to benefit from Guilford Pharmaceuticals' brain implant wafer. The government has created a new classification for it*--and that means […]


Is there a pain in your head?
  by htacio
By Henrylito D. Tacio   On May 3, 2002, 37-year-old Emma Salle and her three Filipino friends – all from Metro Manila -- went to the nature-laden Baguio for relaxation […]


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Pharmaceutical, Biotechnology, and Croaker Fuse Conciliarism Webcast
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MGI PHARMA so that Contribute at the 2007 Merrill Annihilate Cosmic Pharmaceutical, Biotechnology and Chiropractic AM-FM receiver Huddle MINNEAPOLIS--(Bounden duty Cord)--MGI PHARMA, INC. […]


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MGI PHARMA upon Give words to at the 2007 Merrill Purge Unconditioned Pharmaceutical, Biotechnology and Hydropathic Scurvy trick Powwow MINNEAPOLIS--(Syndicate Electric cable)--MGI PHARMA, […]


Pharmaceutical, Biotechnology, and Neurological Signet Round table Webcast
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MGI PHARMA upon Give words to at the 2007 Merrill Purge Unconditioned Pharmaceutical, Biotechnology and Hydropathic Scurvy trick Powwow MINNEAPOLIS--(Syndicate Electric cable)--MGI PHARMA, […]


Cancer Patient Beats the Odds, Hopes to Inspire Others
  by petersimpson006
James Nebus, 71, never expected to walk his daughter down the aisle or see the birth of his first grandson. While the holiday time is supposed to joyful, that […]


Management of Glioblastoma Multiforme
  by Yasser Metwally
The author: Professor Yasser Metwally http://yassermetwally.com INTRODUCTION March 14, 2009 — The treatment of patients with glioblastoma multiforme (GBM) is conventionally considered to be a palliative venture with no hope of […]


Current Management of High-grade Astrocytic Neoplasms: Small but Tangible Progress
  by Yasser Metwally
The author: Professor Yasser Metwally http://yassermetwally.com INTRODUCTION March15, 2009 — The last five years have seen an evolution in the management of highgrade astrocytic tumors comparable in scope yet greater in […]


Drug Ads that Lie
  by theresma
Well, misrepresent, anyway.http://online.wsj.com/article/BT-CO-20100617-712777.html?mod=dist_smartbriefJUNE 17, 2010, 4:00 P.M. ET 2nd UPDATE: FDA Warns Drug Makers On Misleading Promotional Efforts (Adds comment from Eisai in eighth paragraph.) […]



Other reviews about Gliadel on web:

GLIADEL® Wafer (polifeprosan 20 with carmustine implant) is indicated in patients with newly-diagnosed high-grade malignant glioma as an adjunct to surgery and radiation. GLIADEL® Wafer (polifeprosan 20 with carmustine implant ...


Indications and Important Safety Information GLIADEL ® Wafer (polifeprosan 20 with carmustine implant) is indicated in patients with newly-diagnosed high-grade malignant ... Indications


Brain tumor treatment information: new treatments, virtual brain tumor trial, brain tumor links, important papers: Brain Tumor Treatments: Gliadel® Wafer. Brain Tumor Treatments: Gliadel® Wafer


Learn about the prescription medication Gliadel (Polifeprosan 20 with Carmustine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Gliadel (Polifeprosan 20 with Carmustine) Drug Information: Uses ...


Physician reviewed Gliadel patient information - includes Gliadel description, dosage and directions. Gliadel (carmustine) medical facts from Drugs.com


Brain tumor treatment information: new treatments, virtual brain tumor trial, brain tumor links, important papers: Gliadel long term results. Gliadel long term results


Gliadel (carmustine) patient information. Detailed drug information for the consumer, includes dosage, Gliadel side effects and more. Gliadel consumer information from Drugs.com


Gliadel® (polifeprosan 20 with carmustine implant) Wafer for treatment of malignant gliomas and glioblastoma multiforme brain tumors GLIADEL | Brain Tumor Treatment for malignant giloma from Eisai


Gliadel® Neurosurgery A chemotherapy–polifeprosan + carmustine– saturated wafer implanted during surgery to ↓ local recurrence of glioblastoma Side effects Seizures ... Gliadel - definition of Gliadel in the Medical dictionary - by the ...


Gliadel News. Find breaking news, commentary, and archival information about Gliadel from the Baltimore Sun Articles about Gliadel - Baltimore Sun





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