Reviews Forane


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Forane Drug Description
FORANE
(isoflurane, USP) Liquid For Inhalation
DRUG DESCRIPTION
FORANE (isoflurane, USP), a nonflammable liquid administered by vaporizing,
is a general inhalation anesthetic drug. It is 1-chloro-2, 2,2-trifluoroethyl
difluoromethyl ether, and its structural formula is:








Some physical constants are:
Molecular weight..............................184.5
Boiling point at 760 mm Hg...................48.5ツーC (uncorr.)
Refractive index n20D..........................1.2990-1.3005
Specific gravity 25ツー/25ツーC....................1.496
Vapor pressure in mm Hg**
20ツーC........238
25ツーC...........295
30ツーC...........367
35ツーC...........450
**Equation for vapor pressure calculation:
log10Pvap = A + B/T where A = 8.056 T
B = -1664.58
T = ツーC + 273.16 (Kelvin)
Partition coefficients at 37ツーC:
Water/gas.................0.61
Blood/gas.................1.43
Oil/gas.......................90.8
Partition coefficients at 25ツーC - rubber and plastic
Conductive rubber/gas.................62.0
Butyl rubber/gas.................75.0
Polyvinyl chloride/gas.................110.0
Polyethylene/gas.................~2.0
Polyurethane/gas................. ~1.4
Polyolefin/gas .................~1.1
Butyl acetate/gas................. ~2.5
Purity by gas chromatography ................. > 99.9%
Lower limit of flammability in oxygen or nitrous oxide at 9 joules/sec. and
23ツーC.................None
Lower limit of flammability in oxygen or nitrous oxide at 900 joules/sec. and
23ツーC.................Greater than useful concentration in anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures), and does not attack aluminum, tin, brass, iron or copper.Last reviewed on RxList: 3/12/2010




Forane Drug Description
FORANE
(isoflurane, USP) Liquid For Inhalation
DRUG DESCRIPTION
FORANE (isoflurane, USP), a nonflammable liquid administered by vaporizing,
is a general inhalation anesthetic drug. It is 1-chloro-2, 2,2-trifluoroethyl
difluoromethyl ether, and its structural formula is:








Some physical constants are:
Molecular weight..............................184.5
Boiling point at 760 mm Hg...................48.5ツーC (uncorr.)
Refractive index n20D..........................1.2990-1.3005
Specific gravity 25ツー/25ツーC....................1.496
Vapor pressure in mm Hg**
20ツーC........238
25ツーC...........295
30ツーC...........367
35ツーC...........450
**Equation for vapor pressure calculation:
log10Pvap = A + B/T where A = 8.056 T
B = -1664.58
T = ツーC + 273.16 (Kelvin)
Partition coefficients at 37ツーC:
Water/gas.................0.61
Blood/gas.................1.43
Oil/gas.......................90.8
Partition coefficients at 25ツーC - rubber and plastic
Conductive rubber/gas.................62.0
Butyl rubber/gas.................75.0
Polyvinyl chloride/gas.................110.0
Polyethylene/gas.................~2.0
Polyurethane/gas................. ~1.4
Polyolefin/gas .................~1.1
Butyl acetate/gas................. ~2.5
Purity by gas chromatography ................. > 99.9%
Lower limit of flammability in oxygen or nitrous oxide at 9 joules/sec. and
23ツーC.................None
Lower limit of flammability in oxygen or nitrous oxide at 900 joules/sec. and
23ツーC.................Greater than useful concentration in anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures), and does not attack aluminum, tin, brass, iron or copper.Last reviewed on RxList: 3/12/2010




Forane Drug Description
FORANE
(isoflurane, USP) Liquid For Inhalation
DRUG DESCRIPTION
FORANE (isoflurane, USP), a nonflammable liquid administered by vaporizing,
is a general inhalation anesthetic drug. It is 1-chloro-2, 2,2-trifluoroethyl
difluoromethyl ether, and its structural formula is:








Some physical constants are:
Molecular weight..............................184.5
Boiling point at 760 mm Hg...................48.5ツーC (uncorr.)
Refractive index n20D..........................1.2990-1.3005
Specific gravity 25ツー/25ツーC....................1.496
Vapor pressure in mm Hg**
20ツーC........238
25ツーC...........295
30ツーC...........367
35ツーC...........450
**Equation for vapor pressure calculation:
log10Pvap = A + B/T where A = 8.056 T
B = -1664.58
T = ツーC + 273.16 (Kelvin)
Partition coefficients at 37ツーC:
Water/gas.................0.61
Blood/gas.................1.43
Oil/gas.......................90.8
Partition coefficients at 25ツーC - rubber and plastic
Conductive rubber/gas.................62.0
Butyl rubber/gas.................75.0
Polyvinyl chloride/gas.................110.0
Polyethylene/gas.................~2.0
Polyurethane/gas................. ~1.4
Polyolefin/gas .................~1.1
Butyl acetate/gas................. ~2.5
Purity by gas chromatography ................. > 99.9%
Lower limit of flammability in oxygen or nitrous oxide at 9 joules/sec. and
23ツーC.................None
Lower limit of flammability in oxygen or nitrous oxide at 900 joules/sec. and
23ツーC.................Greater than useful concentration in anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures), and does not attack aluminum, tin, brass, iron or copper.Last reviewed on RxList: 3/12/2010




Forane Drug Description
FORANE
(isoflurane, USP) Liquid For Inhalation
DRUG DESCRIPTION
FORANE (isoflurane, USP), a nonflammable liquid administered by vaporizing,
is a general inhalation anesthetic drug. It is 1-chloro-2, 2,2-trifluoroethyl
difluoromethyl ether, and its structural formula is:








Some physical constants are:
Molecular weight..............................184.5
Boiling point at 760 mm Hg...................48.5ツーC (uncorr.)
Refractive index n20D..........................1.2990-1.3005
Specific gravity 25ツー/25ツーC....................1.496
Vapor pressure in mm Hg**
20ツーC........238
25ツーC...........295
30ツーC...........367
35ツーC...........450
**Equation for vapor pressure calculation:
log10Pvap = A + B/T where A = 8.056 T
B = -1664.58
T = ツーC + 273.16 (Kelvin)
Partition coefficients at 37ツーC:
Water/gas.................0.61
Blood/gas.................1.43
Oil/gas.......................90.8
Partition coefficients at 25ツーC - rubber and plastic
Conductive rubber/gas.................62.0
Butyl rubber/gas.................75.0
Polyvinyl chloride/gas.................110.0
Polyethylene/gas.................~2.0
Polyurethane/gas................. ~1.4
Polyolefin/gas .................~1.1
Butyl acetate/gas................. ~2.5
Purity by gas chromatography ................. > 99.9%
Lower limit of flammability in oxygen or nitrous oxide at 9 joules/sec. and
23ツーC.................None
Lower limit of flammability in oxygen or nitrous oxide at 900 joules/sec. and
23ツーC.................Greater than useful concentration in anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures), and does not attack aluminum, tin, brass, iron or copper.Last reviewed on RxList: 3/12/2010




Forane Drug Description
FORANE
(isoflurane, USP) Liquid For Inhalation
DRUG DESCRIPTION
FORANE (isoflurane, USP), a nonflammable liquid administered by vaporizing,
is a general inhalation anesthetic drug. It is 1-chloro-2, 2,2-trifluoroethyl
difluoromethyl ether, and its structural formula is:








Some physical constants are:
Molecular weight..............................184.5
Boiling point at 760 mm Hg...................48.5ツーC (uncorr.)
Refractive index n20D..........................1.2990-1.3005
Specific gravity 25ツー/25ツーC....................1.496
Vapor pressure in mm Hg**
20ツーC........238
25ツーC...........295
30ツーC...........367
35ツーC...........450
**Equation for vapor pressure calculation:
log10Pvap = A + B/T where A = 8.056 T
B = -1664.58
T = ツーC + 273.16 (Kelvin)
Partition coefficients at 37ツーC:
Water/gas.................0.61
Blood/gas.................1.43
Oil/gas.......................90.8
Partition coefficients at 25ツーC - rubber and plastic
Conductive rubber/gas.................62.0
Butyl rubber/gas.................75.0
Polyvinyl chloride/gas.................110.0
Polyethylene/gas.................~2.0
Polyurethane/gas................. ~1.4
Polyolefin/gas .................~1.1
Butyl acetate/gas................. ~2.5
Purity by gas chromatography ................. > 99.9%
Lower limit of flammability in oxygen or nitrous oxide at 9 joules/sec. and
23ツーC.................None
Lower limit of flammability in oxygen or nitrous oxide at 900 joules/sec. and
23ツーC.................Greater than useful concentration in anesthesia.
Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp, 115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures), and does not attack aluminum, tin, brass, iron or copper.Last reviewed on RxList: 3/12/2010





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Other reviews about Forane on web:

Learn about the prescription medication Forane (Isoflurane), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Forane (Isoflurane) Drug Information: Uses, Side Effects, Drug ...


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