Reviews Filgrastim


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Neupogen Drug Description
NEUPOGEN®
(filgrastim)
DRUG DESCRIPTION



What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or...
Read All Potential Side Effects for Neupogen »




Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1
NEUPOGEN® is produced by Escherichia coli (E coli) bacteria
into which has been inserted the human granulocyte colony-stimulating factor
gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has
an amino acid sequence that is identical to the natural sequence predicted from
human DNA sequence analysis‚ except for the addition of an N-terminal methionine
necessary for expression in E coli. Because NEUPOGEN® is produced
in E coli‚ the product is nonglycosylated and thus differs from G-CSF
isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for
parenteral administration containing Filgrastim at a specific activity of 1.0
± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay).
The product is available in single use vials and prefilled syringes. The single
use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0
mL or 1.6 mL, respectively. The single use prefilled syringes contain either
300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively.
See table below for product composition of each single use vial or prefilled
syringe.



 
300 mcg/1.0 mL Vial
480 mcg/1.6 mL Vial
300 mcg/0.5 mL Syringe
480 mcg/0.8 mL Syringe


Filgrastim
300 mcg
480 mcg
300 mcg
480 mcg


Acetate
0.59 mg
0.94 mg
0.295 mg
0.472 mg


Sorbitol
50.0 mg
80.0 mg
25.0 mg
40.0 mg


Polysorbate 80
0.04 mg
0.064 mg
0.02 mg
0.032 mg


Sodium
0.035 mg
0.056 mg
0.0175 mg
0.028 mg


Water for Injection USP q.s. ad
1.0 mL
1.6 mL
0.5 mL
0.8 mL



REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte
colony- stimulating factor: Molecular and biological characterization. Immunobiol.
1986;172:175-184.

Last reviewed on RxList: 4/18/2008




Neupogen Drug Description
NEUPOGEN®
(filgrastim)
DRUG DESCRIPTION



What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or...
Read All Potential Side Effects for Neupogen »




Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1
NEUPOGEN® is produced by Escherichia coli (E coli) bacteria
into which has been inserted the human granulocyte colony-stimulating factor
gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has
an amino acid sequence that is identical to the natural sequence predicted from
human DNA sequence analysis‚ except for the addition of an N-terminal methionine
necessary for expression in E coli. Because NEUPOGEN® is produced
in E coli‚ the product is nonglycosylated and thus differs from G-CSF
isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for
parenteral administration containing Filgrastim at a specific activity of 1.0
± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay).
The product is available in single use vials and prefilled syringes. The single
use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0
mL or 1.6 mL, respectively. The single use prefilled syringes contain either
300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively.
See table below for product composition of each single use vial or prefilled
syringe.



 
300 mcg/1.0 mL Vial
480 mcg/1.6 mL Vial
300 mcg/0.5 mL Syringe
480 mcg/0.8 mL Syringe


Filgrastim
300 mcg
480 mcg
300 mcg
480 mcg


Acetate
0.59 mg
0.94 mg
0.295 mg
0.472 mg


Sorbitol
50.0 mg
80.0 mg
25.0 mg
40.0 mg


Polysorbate 80
0.04 mg
0.064 mg
0.02 mg
0.032 mg


Sodium
0.035 mg
0.056 mg
0.0175 mg
0.028 mg


Water for Injection USP q.s. ad
1.0 mL
1.6 mL
0.5 mL
0.8 mL



REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte
colony- stimulating factor: Molecular and biological characterization. Immunobiol.
1986;172:175-184.

Last reviewed on RxList: 4/18/2008




Neupogen Drug Description
NEUPOGEN®
(filgrastim)
DRUG DESCRIPTION



What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or...
Read All Potential Side Effects for Neupogen »




Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1
NEUPOGEN® is produced by Escherichia coli (E coli) bacteria
into which has been inserted the human granulocyte colony-stimulating factor
gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has
an amino acid sequence that is identical to the natural sequence predicted from
human DNA sequence analysis‚ except for the addition of an N-terminal methionine
necessary for expression in E coli. Because NEUPOGEN® is produced
in E coli‚ the product is nonglycosylated and thus differs from G-CSF
isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for
parenteral administration containing Filgrastim at a specific activity of 1.0
± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay).
The product is available in single use vials and prefilled syringes. The single
use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0
mL or 1.6 mL, respectively. The single use prefilled syringes contain either
300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively.
See table below for product composition of each single use vial or prefilled
syringe.



 
300 mcg/1.0 mL Vial
480 mcg/1.6 mL Vial
300 mcg/0.5 mL Syringe
480 mcg/0.8 mL Syringe


Filgrastim
300 mcg
480 mcg
300 mcg
480 mcg


Acetate
0.59 mg
0.94 mg
0.295 mg
0.472 mg


Sorbitol
50.0 mg
80.0 mg
25.0 mg
40.0 mg


Polysorbate 80
0.04 mg
0.064 mg
0.02 mg
0.032 mg


Sodium
0.035 mg
0.056 mg
0.0175 mg
0.028 mg


Water for Injection USP q.s. ad
1.0 mL
1.6 mL
0.5 mL
0.8 mL



REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte
colony- stimulating factor: Molecular and biological characterization. Immunobiol.
1986;172:175-184.

Last reviewed on RxList: 4/18/2008




Neupogen Drug Description
NEUPOGEN®
(filgrastim)
DRUG DESCRIPTION



What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or...
Read All Potential Side Effects for Neupogen »




Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1
NEUPOGEN® is produced by Escherichia coli (E coli) bacteria
into which has been inserted the human granulocyte colony-stimulating factor
gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has
an amino acid sequence that is identical to the natural sequence predicted from
human DNA sequence analysis‚ except for the addition of an N-terminal methionine
necessary for expression in E coli. Because NEUPOGEN® is produced
in E coli‚ the product is nonglycosylated and thus differs from G-CSF
isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for
parenteral administration containing Filgrastim at a specific activity of 1.0
± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay).
The product is available in single use vials and prefilled syringes. The single
use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0
mL or 1.6 mL, respectively. The single use prefilled syringes contain either
300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively.
See table below for product composition of each single use vial or prefilled
syringe.



 
300 mcg/1.0 mL Vial
480 mcg/1.6 mL Vial
300 mcg/0.5 mL Syringe
480 mcg/0.8 mL Syringe


Filgrastim
300 mcg
480 mcg
300 mcg
480 mcg


Acetate
0.59 mg
0.94 mg
0.295 mg
0.472 mg


Sorbitol
50.0 mg
80.0 mg
25.0 mg
40.0 mg


Polysorbate 80
0.04 mg
0.064 mg
0.02 mg
0.032 mg


Sodium
0.035 mg
0.056 mg
0.0175 mg
0.028 mg


Water for Injection USP q.s. ad
1.0 mL
1.6 mL
0.5 mL
0.8 mL



REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte
colony- stimulating factor: Molecular and biological characterization. Immunobiol.
1986;172:175-184.

Last reviewed on RxList: 4/18/2008




Neupogen Drug Description
NEUPOGEN®
(filgrastim)
DRUG DESCRIPTION



What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or...
Read All Potential Side Effects for Neupogen »




Filgrastim is a human granulocyte colony-stimulating factor (G-CSF)‚ produced by recombinant DNA technology. NEUPOGEN® is the Amgen Inc. trademark for Filgrastim‚ which has been selected as the name for recombinant methionyl human granulocyte colony-stimulating factor (r-metHuG-CSF).
NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1
NEUPOGEN® is produced by Escherichia coli (E coli) bacteria
into which has been inserted the human granulocyte colony-stimulating factor
gene. NEUPOGEN® has a molecular weight of 18‚800 daltons. The protein has
an amino acid sequence that is identical to the natural sequence predicted from
human DNA sequence analysis‚ except for the addition of an N-terminal methionine
necessary for expression in E coli. Because NEUPOGEN® is produced
in E coli‚ the product is nonglycosylated and thus differs from G-CSF
isolated from a human cell.
NEUPOGEN® is a sterile‚ clear‚ colorless‚ preservative-free liquid for
parenteral administration containing Filgrastim at a specific activity of 1.0
± 0.6 x 108 U/mg (as measured by a cell mitogenesis assay).
The product is available in single use vials and prefilled syringes. The single
use vials contain either 300 mcg or 480 mcg Filgrastim at a fill volume of 1.0
mL or 1.6 mL, respectively. The single use prefilled syringes contain either
300 mcg or 480 mcg Filgrastim at a fill volume of 0.5 mL or 0.8 mL, respectively.
See table below for product composition of each single use vial or prefilled
syringe.



 
300 mcg/1.0 mL Vial
480 mcg/1.6 mL Vial
300 mcg/0.5 mL Syringe
480 mcg/0.8 mL Syringe


Filgrastim
300 mcg
480 mcg
300 mcg
480 mcg


Acetate
0.59 mg
0.94 mg
0.295 mg
0.472 mg


Sorbitol
50.0 mg
80.0 mg
25.0 mg
40.0 mg


Polysorbate 80
0.04 mg
0.064 mg
0.02 mg
0.032 mg


Sodium
0.035 mg
0.056 mg
0.0175 mg
0.028 mg


Water for Injection USP q.s. ad
1.0 mL
1.6 mL
0.5 mL
0.8 mL



REFERENCES
1. Zsebo KM‚ Cohen AM‚ Murdock DC‚ et al. Recombinant human granulocyte
colony- stimulating factor: Molecular and biological characterization. Immunobiol.
1986;172:175-184.

Last reviewed on RxList: 4/18/2008





Other reviews about Filgrastim on wordpress

Day 128 / Only 208 days left
  by Lynne
I had my bloods taken on Monday and I saw Dr Sree yesterday.  There is very little change in any of my results, the neuts continue to be […]


Day 130 / 206 days left
  by Lynne
Medical Notes on Filgrastim/Neupogen   Why is this medication prescribed?   Return to top Filgrastim is used to decrease the chance of infection in […]


Sandoz Receives Positive EU Opinion For Biosimilar Filgrastim
  by yestelli
Sandoz has received a positive opinion from European regulators for its third biosimilar medicine, filgrastim, marking another important milestone in its efforts to bring affordable high-quality biopharmaceuticals to […]


Sandoz Receives European Commission Approval For Biosimilar Filgrastim
  by enartion
Sandoz has received final approval for its third biosimilar, filgrastim, paving the way for this important oncology medicine to be made available to patients across the European Union. […]


Moderate Neutropenic at 420
  by James Gommel
Kaylee's first clinic visit was no surprise - her white blood-cell counts were low, which means she is Moderate Neutropenic.  What does this mean?  No visitors that have been, […]


Filgrastim, continued
  by hunterseeker
Today was the second day of my chemo. I had explained to the attending nurse the pain I had experienced from using Filgrastim over the past days. I […]


Return to Filgrastim
  by hunterseeker
Well after thinking that my experiences with Filgrastim injections were over I was reminded that I have to take the medication before and AFTER chemo. I am scheduled for […]


Filgrastim, Day 2!
  by Caitlin Emma
Today is the second day on the medication, Filgrastim, to grow my blood cells faster! Yesterday went well, we did not get anywhere close to lost thanks to […]


Sittin' in Bed...Allllllll Day Three.
  by Caitlin Emma
Today was my third day on Filgrastim. I still have a pretty decent headache, back pain and now hip pain. Sometimes I see spots, and there's an occasional […]



Other reviews about Filgrastim on web:

Filgrastim is a granulocyte colony-stimulating factor (G-CSF) analog used to stimulate the proliferation and differentiation of granulocytes It is produced by recombinant DNA ... Filgrastim - Wikipedia, the free encyclopedia


Consumer information. Typical dosage and length of treatment, possible side effects, how to store this drug. At Medline Plus. Filgrastim Injection: MedlinePlus Drug Information


Filgrastim Key Terms: Food and Drug Administration , Chemotherapy , Subcutaneous , Intravenous , Reinfusion , Neutropenia , Recovery , Apheresis , Filgrastim: Information from Answers.com


This site is currently being updated. Please check back shortly. Download PDF Version of NEUPOGEN ® Prescribing Information. Download PDF Version of NEUPOGEN ® Patient ... NEUPOGEN® Filgrastim - Product Information


Consumer information about the medication FILGRASTIM - INJECTION (Neupogen), includes side effects, drug interactions, recommended dosages, and storage information. Read more ... FILGRASTIM - INJECTION (Neupogen) side effects, medical uses, and ...


All about Filgrastim. View complete and up to date Filgrastim information - part of the Drugs.com trusted medication database. Filgrastim Facts and Comparisons at Drugs.com


Learn about the prescription medication Neupogen (Filgrastim), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Neupogen (Filgrastim) Drug Information: Uses, Side Effects, Drug ...


Filgrastim (G-CSF) professional patient advice. Specific and up to date information about Filgrastim (G-CSF). Complete Filgrastim (G-CSF) information from Drugs.com


This page contains brief information about filgrastim and a collection of links to more information about the use of this drug, related news and research results, and ongoing ... Filgrastim - National Cancer Institute


Filgrastim is a biologic response modifier. It is classified as a colony stimulating factor. G-CSF, Neupogen Filgrastim, G-CSF, Neupogen - Chemotherapy Drugs, Chemo Drug Side ...





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