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Fanapt Drug Description
FANAPT™
(iloperidone) Tablets

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analysis of seventeen placebo-controlled
trials (modal duration 10 weeks), largely in patients taking atypical antipsychotic
drugs, revealed a risk of death in the drug-treated patients of between 1.6
to 1.7 times the risk of death in placebo-treated patients. Over the course
of a typical 10-week controlled trial, the rate of death in drug-treated patients
was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although
the causes of death were varied, most of the deaths appeared to be either cardiovascular
(e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Observational studies suggest that, similar to atypical antipsychotic drugs,
treatment with conventional antipsychotic drugs may increase mortality. The
extent to which the findings of increased mortality in observational studies
may be attributed to the antipsychotic drug as opposed to some characteristics(s)
of the patients is not clear. FANAPT is not approved for the treatment of
patients with Dementia-Related Psychosis. [see WARNINGS AND PRECAUTIONS]

DRUG DESCRIPTION



What are the possible side effects of iloperidone (Fanapt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
...
Read All Potential Side Effects for Fanapt »




FANAPT is a psychotropic agent belonging to the chemical class of piperidinyl-benzisoxazole
derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone.
Its molecular formula is C24H27FN2O4
and its molecular weight is 426.48. The structural formula is:








Iloperidone is a white to off-white finely crystalline powder. It is practically insoluble in water, very slightly soluble in 0.1 N HCl and freely soluble in chloroform, ethanol, methanol, and acetonitrile.
FANAPT tablets are intended for oral administration only. Each round, uncoated
tablet contains 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, or 12 mg of iloperidone.
Inactive ingredients are: lactose monohydrate, microcrystalline cellulose, hydroxypropylmethylcellulose,
crospovidone, magnesium stearate, colloidal silicon dioxide, and purified water
(removed during processing). The tablets are white, round, flat, beveled- edged
and identified with a logo “ ” debossed on one side and tablet strength “1”,
“2”, “4”, “6”, “8”, “10”, or “12” debossed on the other side.
Last reviewed on RxList: 5/21/2009




Fanapt Drug Description
FANAPT™
(iloperidone) Tablets

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analysis of seventeen placebo-controlled
trials (modal duration 10 weeks), largely in patients taking atypical antipsychotic
drugs, revealed a risk of death in the drug-treated patients of between 1.6
to 1.7 times the risk of death in placebo-treated patients. Over the course
of a typical 10-week controlled trial, the rate of death in drug-treated patients
was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although
the causes of death were varied, most of the deaths appeared to be either cardiovascular
(e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Observational studies suggest that, similar to atypical antipsychotic drugs,
treatment with conventional antipsychotic drugs may increase mortality. The
extent to which the findings of increased mortality in observational studies
may be attributed to the antipsychotic drug as opposed to some characteristics(s)
of the patients is not clear. FANAPT is not approved for the treatment of
patients with Dementia-Related Psychosis. [see WARNINGS AND PRECAUTIONS]

DRUG DESCRIPTION



What are the possible side effects of iloperidone (Fanapt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
...
Read All Potential Side Effects for Fanapt »




FANAPT is a psychotropic agent belonging to the chemical class of piperidinyl-benzisoxazole
derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone.
Its molecular formula is C24H27FN2O4
and its molecular weight is 426.48. The structural formula is:








Iloperidone is a white to off-white finely crystalline powder. It is practically insoluble in water, very slightly soluble in 0.1 N HCl and freely soluble in chloroform, ethanol, methanol, and acetonitrile.
FANAPT tablets are intended for oral administration only. Each round, uncoated
tablet contains 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, or 12 mg of iloperidone.
Inactive ingredients are: lactose monohydrate, microcrystalline cellulose, hydroxypropylmethylcellulose,
crospovidone, magnesium stearate, colloidal silicon dioxide, and purified water
(removed during processing). The tablets are white, round, flat, beveled- edged
and identified with a logo “ ” debossed on one side and tablet strength “1”,
“2”, “4”, “6”, “8”, “10”, or “12” debossed on the other side.
Last reviewed on RxList: 5/21/2009




Fanapt Drug Description
FANAPT™
(iloperidone) Tablets

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analysis of seventeen placebo-controlled
trials (modal duration 10 weeks), largely in patients taking atypical antipsychotic
drugs, revealed a risk of death in the drug-treated patients of between 1.6
to 1.7 times the risk of death in placebo-treated patients. Over the course
of a typical 10-week controlled trial, the rate of death in drug-treated patients
was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although
the causes of death were varied, most of the deaths appeared to be either cardiovascular
(e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Observational studies suggest that, similar to atypical antipsychotic drugs,
treatment with conventional antipsychotic drugs may increase mortality. The
extent to which the findings of increased mortality in observational studies
may be attributed to the antipsychotic drug as opposed to some characteristics(s)
of the patients is not clear. FANAPT is not approved for the treatment of
patients with Dementia-Related Psychosis. [see WARNINGS AND PRECAUTIONS]

DRUG DESCRIPTION



What are the possible side effects of iloperidone (Fanapt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
...
Read All Potential Side Effects for Fanapt »




FANAPT is a psychotropic agent belonging to the chemical class of piperidinyl-benzisoxazole
derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone.
Its molecular formula is C24H27FN2O4
and its molecular weight is 426.48. The structural formula is:








Iloperidone is a white to off-white finely crystalline powder. It is practically insoluble in water, very slightly soluble in 0.1 N HCl and freely soluble in chloroform, ethanol, methanol, and acetonitrile.
FANAPT tablets are intended for oral administration only. Each round, uncoated
tablet contains 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, or 12 mg of iloperidone.
Inactive ingredients are: lactose monohydrate, microcrystalline cellulose, hydroxypropylmethylcellulose,
crospovidone, magnesium stearate, colloidal silicon dioxide, and purified water
(removed during processing). The tablets are white, round, flat, beveled- edged
and identified with a logo “ ” debossed on one side and tablet strength “1”,
“2”, “4”, “6”, “8”, “10”, or “12” debossed on the other side.
Last reviewed on RxList: 5/21/2009




Fanapt Drug Description
FANAPT™
(iloperidone) Tablets

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analysis of seventeen placebo-controlled
trials (modal duration 10 weeks), largely in patients taking atypical antipsychotic
drugs, revealed a risk of death in the drug-treated patients of between 1.6
to 1.7 times the risk of death in placebo-treated patients. Over the course
of a typical 10-week controlled trial, the rate of death in drug-treated patients
was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although
the causes of death were varied, most of the deaths appeared to be either cardiovascular
(e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Observational studies suggest that, similar to atypical antipsychotic drugs,
treatment with conventional antipsychotic drugs may increase mortality. The
extent to which the findings of increased mortality in observational studies
may be attributed to the antipsychotic drug as opposed to some characteristics(s)
of the patients is not clear. FANAPT is not approved for the treatment of
patients with Dementia-Related Psychosis. [see WARNINGS AND PRECAUTIONS]

DRUG DESCRIPTION



What are the possible side effects of iloperidone (Fanapt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
...
Read All Potential Side Effects for Fanapt »




FANAPT is a psychotropic agent belonging to the chemical class of piperidinyl-benzisoxazole
derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone.
Its molecular formula is C24H27FN2O4
and its molecular weight is 426.48. The structural formula is:








Iloperidone is a white to off-white finely crystalline powder. It is practically insoluble in water, very slightly soluble in 0.1 N HCl and freely soluble in chloroform, ethanol, methanol, and acetonitrile.
FANAPT tablets are intended for oral administration only. Each round, uncoated
tablet contains 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, or 12 mg of iloperidone.
Inactive ingredients are: lactose monohydrate, microcrystalline cellulose, hydroxypropylmethylcellulose,
crospovidone, magnesium stearate, colloidal silicon dioxide, and purified water
(removed during processing). The tablets are white, round, flat, beveled- edged
and identified with a logo “ ” debossed on one side and tablet strength “1”,
“2”, “4”, “6”, “8”, “10”, or “12” debossed on the other side.
Last reviewed on RxList: 5/21/2009




Fanapt Drug Description
FANAPT™
(iloperidone) Tablets

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
Elderly patients with dementia-related psychosis treated with antipsychotic
drugs are at an increased risk of death. Analysis of seventeen placebo-controlled
trials (modal duration 10 weeks), largely in patients taking atypical antipsychotic
drugs, revealed a risk of death in the drug-treated patients of between 1.6
to 1.7 times the risk of death in placebo-treated patients. Over the course
of a typical 10-week controlled trial, the rate of death in drug-treated patients
was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although
the causes of death were varied, most of the deaths appeared to be either cardiovascular
(e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.
Observational studies suggest that, similar to atypical antipsychotic drugs,
treatment with conventional antipsychotic drugs may increase mortality. The
extent to which the findings of increased mortality in observational studies
may be attributed to the antipsychotic drug as opposed to some characteristics(s)
of the patients is not clear. FANAPT is not approved for the treatment of
patients with Dementia-Related Psychosis. [see WARNINGS AND PRECAUTIONS]

DRUG DESCRIPTION



What are the possible side effects of iloperidone (Fanapt)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medication and call your doctor at once if you have a serious side effect such as:

very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
...
Read All Potential Side Effects for Fanapt »




FANAPT is a psychotropic agent belonging to the chemical class of piperidinyl-benzisoxazole
derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone.
Its molecular formula is C24H27FN2O4
and its molecular weight is 426.48. The structural formula is:








Iloperidone is a white to off-white finely crystalline powder. It is practically insoluble in water, very slightly soluble in 0.1 N HCl and freely soluble in chloroform, ethanol, methanol, and acetonitrile.
FANAPT tablets are intended for oral administration only. Each round, uncoated
tablet contains 1 mg, 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, or 12 mg of iloperidone.
Inactive ingredients are: lactose monohydrate, microcrystalline cellulose, hydroxypropylmethylcellulose,
crospovidone, magnesium stearate, colloidal silicon dioxide, and purified water
(removed during processing). The tablets are white, round, flat, beveled- edged
and identified with a logo “ ” debossed on one side and tablet strength “1”,
“2”, “4”, “6”, “8”, “10”, or “12” debossed on the other side.
Last reviewed on RxList: 5/21/2009





Other reviews about Fanapt on wordpress

FDA approves new antipsychotic for schizophrenia -- Fanapt
  by giannakali
As you know drugs that get approved for Schizophrenia quickly get used off-label for everything. Risperdal was on the market only for one month, approved for schizophrenia, when […]


Vanda Pharmaceuticals Inc (NASDAQ:VNDA) up on FDA approval; Greenbackd exits
  by greenbackd
Vanda Pharmaceuticals Inc. (NASDAQ:VNDA) yesterday announced that the US Food and Drug Administration (FDA) had granted marketing approval following its Phase III clinical study of Fanapt™ (iloperidone). Tang […]


Fanapt Sanctioned for Schizophrenia
  by timeinctemp
THURSDAY, May 7 (HealthDay News) — A new pill to treat adults with schizophrenia has been approved by the U.S. Food and Drug Administration. Fanapt (iloperidone), which belongs to […]


Trends Update -- Comparative Effectiveness: To Head-to-Head or Not To Head-to-Head?
  by Jeremy G
One of the challenges of comparative effectiveness implementation is figuring out when to look for comparative data. Two developments this week shed light on current comparative effectiveness […]


Vanda Pharmaceuticals signs agreement with Novartis
  by silico
Vanda Pharmaceuticals has announced that it has entered into an agreement with Novartis to commercialize and develop Fanapt, Vanda's anti-psychotic, in the U.S. and Canada. Fanapt was […]


New Antipsychotic Targets a Different Combination of Neurotransmitters in Schizophrenia.
  by abrandemihl
The Washington Post (11/2, Musgrove http://tinyurl.com/new-antipsychotic-Fanapt) reports that , "Early next year, if all goes according to plan, doctors will be able to prescribe a new antipsychotic drug for patients […]


Partnering Profile: Novartis
  by silico
How many partners does Novartis have? Novartis lists 67 current alliances on its website. How Novartis forms alliances Novartis's Pharmaceuticals Division and the Novartis Institutes for BioMedical Research form alliances with […]


Abrupt
  by Gemma
My mood has abruptly dropped, feeling quite shite actually. I'm getting worried because Fanapt is so similar to Risperdal, and this is what Risperdal did to me. It […]


Square One
  by Gemma
I don't know how I'm supposed to do this. I'm right back at square one, denying my diagnosis and trying to find ways to refute it. I think […]


Impactiviti Daily 052010 Top Pharma News
  by Steve Woodruff
***** TODAY’S NEWS Novartis: huge punitive fine in discrimination case. $250 million game-changing dollars. FDA to the public - let's talk more. Or, tell us more about what we should tell […]



Other reviews about Fanapt on web:

Fanapt (iloperidone) tablets — Now Available - Official U.S. Website Fanapt (iloperidone) tablets — Official U.S. Website


Learn about the prescription medication Fanapt (Iloperidone Tablets), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Fanapt (Iloperidone Tablets) Drug Information: Uses, Side Effects ...


Fanapt (iloperidone) is an antipsychotic medication used to treat schizophrenia. Includes Fanapt side effects, interactions and indications. Fanapt Information from Drugs.com


Accurate, FDA approved Fanapt information for healthcare professionals and patients - brought to you by Drugs.com. Fanapt Official FDA information, side effects and uses.


The U.S. Food and Drug Administration (FDA) yesterday approved a new psychiatric medication for the treatment of adults with schizophrenia called Fanapt FDA Approves Fanapt for Treatment of Schizophrenia | Psych Central ...


Organized by therapeutic area, this comprehensive listing of FDA-Approved Drugs by the Food and Drug Administration features facts on clinical trial results, side effects and other ... Newly Approved Drug Therapies (1021) Fanapt (iloperidone), Vanda,


View all media releases. January 11, 2010 07:15 CET. Novartis launches schizophrenia treatment Fanapt in the US, offering patients an attractive alternative to existing medications Novartis launches schizophrenia treatment Fanapt in the US ...


A healthcare provider may prescribe Fanapt to treat schizophrenia. This selection from the eMedTV Web site offers an overview of this medication, including how it works, dosing ... Fanapt


Fanapt is an atypical antipsychotic agent used to treat schizophrenia. Side effects and interactions are available at drugstore.com; plus get home delivery from a trusted and ... Fanapt - drugstore.com. Low prices, side effects, interactions.


Iloperidone, also known as Fanapt, Fanapta, and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia. It was approved by the U.S. Food and ... Iloperidone - Wikipedia, the free encyclopedia





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