Reviews Estrogens


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Menest Drug Description
Menest®
(esterified estrogens) Tablets, USP

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important.Adequate
diagnostic measures,including endometrial sampling when indicated, should
be undertaken to rule out malignancy in all cases of undiagnosed persistent
or recurring abnormal vaginal bleeding. There is no evidence that the use
of "natural" estrogens results in a different endometrial risk profile
than synthetic estrogens at equivalent estrogen doses. (See WARNINGS,
Malignant neoplasms, Endometrial cancer.)
CARDIOVASCULAR AND OTHER RISKS
Estrogens with and without progestins should not be used for the prevention
of cardiovascular disease. (See WARNINGS, Cardiovascular
disorders.)
The Women's Health Initiative (WHI) study reported increased risks of myocardial
infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein
thrombosis in postmenopausal women (50 to 79 years of age) during 5 years
of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone
acetate (MPA 2.5 mg) relative to placebo (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
The Women's Health Initiative Memory Study (WHIMS), a sub-study of WHI, reported
increased risk of developing probable dementia in postmenopausal women 65
years of age or older during 4 years of treatment with oral conjugated estrogens
plus medroxyprogesterone acetate relative to placebo. It is unknown whether
this finding applies to younger postmenopausal women or to women taking estrogen
alone therapy. (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
Other doses of conjugated estrogens with medroxyprogesterone acetate,and other
combinations and dosage forms of estrogens and progestins were not studied in
the WHI clinical trials and,in the absence of comparable data,these risks should
be assumed to be similar. Because of these risks, estrogens with or without
progestins should be prescribed at the lowest effective doses and for the shortest
duration consistent with treatment goals and risks for the individual woman.

DRUG DESCRIPTION



What are the possible side effects of esterified estrogens (Estratab, Menest)?

If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
a lump in a breast; or
liver damage (yellowing of the skin or...
Read All Potential Side Effects for Menest »




Esterified estrogens is a mixture of the sodium salts of the sulfate esters
of the estrogenic substances, principally estrone, that are of the type excreted
by pregnant mares. The content of total esterified estrogens is not less than
90 percent and not more than 110 percent of the labeled amount. Esterified estrogens
contain not less than 75 percent and not more than 85 percent of sodium estrone
sulfate, and not less than 6 percent and not more than 15 percent of sodium
equilin sulfate, in such proportion that the total of these two components is
not less than 90 percent, all percentages being calculated on the basis of the
total esterified estrogens content.
Inactive Ingredients: Ethyl cellulose, fragrances, hydroxypropyl cellulose,
hypromellose 2910, lactose, magnesium stearate, methylcellulose, polyethylene
glycol, sodium bicarbonate, shellac, starch, stearic acid, titanium dioxide,
and vanillin. Dyes in the form of aluminum lakes are contained in each tablet
strength as follows: 0.3 mg Tablet: FD&C Yellow No. 6, D&C Yellow
No. 10. 0.625 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10.
1.25 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10, FD&C
Blue No.1. 2.5 mg Tablet: D&C Red No.30.Last reviewed on RxList: 10/28/2008




Menest Drug Description
Menest®
(esterified estrogens) Tablets, USP

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important.Adequate
diagnostic measures,including endometrial sampling when indicated, should
be undertaken to rule out malignancy in all cases of undiagnosed persistent
or recurring abnormal vaginal bleeding. There is no evidence that the use
of "natural" estrogens results in a different endometrial risk profile
than synthetic estrogens at equivalent estrogen doses. (See WARNINGS,
Malignant neoplasms, Endometrial cancer.)
CARDIOVASCULAR AND OTHER RISKS
Estrogens with and without progestins should not be used for the prevention
of cardiovascular disease. (See WARNINGS, Cardiovascular
disorders.)
The Women's Health Initiative (WHI) study reported increased risks of myocardial
infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein
thrombosis in postmenopausal women (50 to 79 years of age) during 5 years
of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone
acetate (MPA 2.5 mg) relative to placebo (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
The Women's Health Initiative Memory Study (WHIMS), a sub-study of WHI, reported
increased risk of developing probable dementia in postmenopausal women 65
years of age or older during 4 years of treatment with oral conjugated estrogens
plus medroxyprogesterone acetate relative to placebo. It is unknown whether
this finding applies to younger postmenopausal women or to women taking estrogen
alone therapy. (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
Other doses of conjugated estrogens with medroxyprogesterone acetate,and other
combinations and dosage forms of estrogens and progestins were not studied in
the WHI clinical trials and,in the absence of comparable data,these risks should
be assumed to be similar. Because of these risks, estrogens with or without
progestins should be prescribed at the lowest effective doses and for the shortest
duration consistent with treatment goals and risks for the individual woman.

DRUG DESCRIPTION



What are the possible side effects of esterified estrogens (Estratab, Menest)?

If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
a lump in a breast; or
liver damage (yellowing of the skin or...
Read All Potential Side Effects for Menest »




Esterified estrogens is a mixture of the sodium salts of the sulfate esters
of the estrogenic substances, principally estrone, that are of the type excreted
by pregnant mares. The content of total esterified estrogens is not less than
90 percent and not more than 110 percent of the labeled amount. Esterified estrogens
contain not less than 75 percent and not more than 85 percent of sodium estrone
sulfate, and not less than 6 percent and not more than 15 percent of sodium
equilin sulfate, in such proportion that the total of these two components is
not less than 90 percent, all percentages being calculated on the basis of the
total esterified estrogens content.
Inactive Ingredients: Ethyl cellulose, fragrances, hydroxypropyl cellulose,
hypromellose 2910, lactose, magnesium stearate, methylcellulose, polyethylene
glycol, sodium bicarbonate, shellac, starch, stearic acid, titanium dioxide,
and vanillin. Dyes in the form of aluminum lakes are contained in each tablet
strength as follows: 0.3 mg Tablet: FD&C Yellow No. 6, D&C Yellow
No. 10. 0.625 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10.
1.25 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10, FD&C
Blue No.1. 2.5 mg Tablet: D&C Red No.30.Last reviewed on RxList: 10/28/2008




Menest Drug Description
Menest®
(esterified estrogens) Tablets, USP

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important.Adequate
diagnostic measures,including endometrial sampling when indicated, should
be undertaken to rule out malignancy in all cases of undiagnosed persistent
or recurring abnormal vaginal bleeding. There is no evidence that the use
of "natural" estrogens results in a different endometrial risk profile
than synthetic estrogens at equivalent estrogen doses. (See WARNINGS,
Malignant neoplasms, Endometrial cancer.)
CARDIOVASCULAR AND OTHER RISKS
Estrogens with and without progestins should not be used for the prevention
of cardiovascular disease. (See WARNINGS, Cardiovascular
disorders.)
The Women's Health Initiative (WHI) study reported increased risks of myocardial
infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein
thrombosis in postmenopausal women (50 to 79 years of age) during 5 years
of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone
acetate (MPA 2.5 mg) relative to placebo (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
The Women's Health Initiative Memory Study (WHIMS), a sub-study of WHI, reported
increased risk of developing probable dementia in postmenopausal women 65
years of age or older during 4 years of treatment with oral conjugated estrogens
plus medroxyprogesterone acetate relative to placebo. It is unknown whether
this finding applies to younger postmenopausal women or to women taking estrogen
alone therapy. (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
Other doses of conjugated estrogens with medroxyprogesterone acetate,and other
combinations and dosage forms of estrogens and progestins were not studied in
the WHI clinical trials and,in the absence of comparable data,these risks should
be assumed to be similar. Because of these risks, estrogens with or without
progestins should be prescribed at the lowest effective doses and for the shortest
duration consistent with treatment goals and risks for the individual woman.

DRUG DESCRIPTION



What are the possible side effects of esterified estrogens (Estratab, Menest)?

If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
a lump in a breast; or
liver damage (yellowing of the skin or...
Read All Potential Side Effects for Menest »




Esterified estrogens is a mixture of the sodium salts of the sulfate esters
of the estrogenic substances, principally estrone, that are of the type excreted
by pregnant mares. The content of total esterified estrogens is not less than
90 percent and not more than 110 percent of the labeled amount. Esterified estrogens
contain not less than 75 percent and not more than 85 percent of sodium estrone
sulfate, and not less than 6 percent and not more than 15 percent of sodium
equilin sulfate, in such proportion that the total of these two components is
not less than 90 percent, all percentages being calculated on the basis of the
total esterified estrogens content.
Inactive Ingredients: Ethyl cellulose, fragrances, hydroxypropyl cellulose,
hypromellose 2910, lactose, magnesium stearate, methylcellulose, polyethylene
glycol, sodium bicarbonate, shellac, starch, stearic acid, titanium dioxide,
and vanillin. Dyes in the form of aluminum lakes are contained in each tablet
strength as follows: 0.3 mg Tablet: FD&C Yellow No. 6, D&C Yellow
No. 10. 0.625 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10.
1.25 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10, FD&C
Blue No.1. 2.5 mg Tablet: D&C Red No.30.Last reviewed on RxList: 10/28/2008




Menest Drug Description
Menest®
(esterified estrogens) Tablets, USP

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important.Adequate
diagnostic measures,including endometrial sampling when indicated, should
be undertaken to rule out malignancy in all cases of undiagnosed persistent
or recurring abnormal vaginal bleeding. There is no evidence that the use
of "natural" estrogens results in a different endometrial risk profile
than synthetic estrogens at equivalent estrogen doses. (See WARNINGS,
Malignant neoplasms, Endometrial cancer.)
CARDIOVASCULAR AND OTHER RISKS
Estrogens with and without progestins should not be used for the prevention
of cardiovascular disease. (See WARNINGS, Cardiovascular
disorders.)
The Women's Health Initiative (WHI) study reported increased risks of myocardial
infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein
thrombosis in postmenopausal women (50 to 79 years of age) during 5 years
of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone
acetate (MPA 2.5 mg) relative to placebo (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
The Women's Health Initiative Memory Study (WHIMS), a sub-study of WHI, reported
increased risk of developing probable dementia in postmenopausal women 65
years of age or older during 4 years of treatment with oral conjugated estrogens
plus medroxyprogesterone acetate relative to placebo. It is unknown whether
this finding applies to younger postmenopausal women or to women taking estrogen
alone therapy. (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
Other doses of conjugated estrogens with medroxyprogesterone acetate,and other
combinations and dosage forms of estrogens and progestins were not studied in
the WHI clinical trials and,in the absence of comparable data,these risks should
be assumed to be similar. Because of these risks, estrogens with or without
progestins should be prescribed at the lowest effective doses and for the shortest
duration consistent with treatment goals and risks for the individual woman.

DRUG DESCRIPTION



What are the possible side effects of esterified estrogens (Estratab, Menest)?

If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
a lump in a breast; or
liver damage (yellowing of the skin or...
Read All Potential Side Effects for Menest »




Esterified estrogens is a mixture of the sodium salts of the sulfate esters
of the estrogenic substances, principally estrone, that are of the type excreted
by pregnant mares. The content of total esterified estrogens is not less than
90 percent and not more than 110 percent of the labeled amount. Esterified estrogens
contain not less than 75 percent and not more than 85 percent of sodium estrone
sulfate, and not less than 6 percent and not more than 15 percent of sodium
equilin sulfate, in such proportion that the total of these two components is
not less than 90 percent, all percentages being calculated on the basis of the
total esterified estrogens content.
Inactive Ingredients: Ethyl cellulose, fragrances, hydroxypropyl cellulose,
hypromellose 2910, lactose, magnesium stearate, methylcellulose, polyethylene
glycol, sodium bicarbonate, shellac, starch, stearic acid, titanium dioxide,
and vanillin. Dyes in the form of aluminum lakes are contained in each tablet
strength as follows: 0.3 mg Tablet: FD&C Yellow No. 6, D&C Yellow
No. 10. 0.625 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10.
1.25 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10, FD&C
Blue No.1. 2.5 mg Tablet: D&C Red No.30.Last reviewed on RxList: 10/28/2008




Menest Drug Description
Menest®
(esterified estrogens) Tablets, USP

ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important.Adequate
diagnostic measures,including endometrial sampling when indicated, should
be undertaken to rule out malignancy in all cases of undiagnosed persistent
or recurring abnormal vaginal bleeding. There is no evidence that the use
of "natural" estrogens results in a different endometrial risk profile
than synthetic estrogens at equivalent estrogen doses. (See WARNINGS,
Malignant neoplasms, Endometrial cancer.)
CARDIOVASCULAR AND OTHER RISKS
Estrogens with and without progestins should not be used for the prevention
of cardiovascular disease. (See WARNINGS, Cardiovascular
disorders.)
The Women's Health Initiative (WHI) study reported increased risks of myocardial
infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein
thrombosis in postmenopausal women (50 to 79 years of age) during 5 years
of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone
acetate (MPA 2.5 mg) relative to placebo (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
The Women's Health Initiative Memory Study (WHIMS), a sub-study of WHI, reported
increased risk of developing probable dementia in postmenopausal women 65
years of age or older during 4 years of treatment with oral conjugated estrogens
plus medroxyprogesterone acetate relative to placebo. It is unknown whether
this finding applies to younger postmenopausal women or to women taking estrogen
alone therapy. (See CLINICAL PHARMACOLOGY, Clinical
Studies.)
Other doses of conjugated estrogens with medroxyprogesterone acetate,and other
combinations and dosage forms of estrogens and progestins were not studied in
the WHI clinical trials and,in the absence of comparable data,these risks should
be assumed to be similar. Because of these risks, estrogens with or without
progestins should be prescribed at the lowest effective doses and for the shortest
duration consistent with treatment goals and risks for the individual woman.

DRUG DESCRIPTION



What are the possible side effects of esterified estrogens (Estratab, Menest)?

If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
a lump in a breast; or
liver damage (yellowing of the skin or...
Read All Potential Side Effects for Menest »




Esterified estrogens is a mixture of the sodium salts of the sulfate esters
of the estrogenic substances, principally estrone, that are of the type excreted
by pregnant mares. The content of total esterified estrogens is not less than
90 percent and not more than 110 percent of the labeled amount. Esterified estrogens
contain not less than 75 percent and not more than 85 percent of sodium estrone
sulfate, and not less than 6 percent and not more than 15 percent of sodium
equilin sulfate, in such proportion that the total of these two components is
not less than 90 percent, all percentages being calculated on the basis of the
total esterified estrogens content.
Inactive Ingredients: Ethyl cellulose, fragrances, hydroxypropyl cellulose,
hypromellose 2910, lactose, magnesium stearate, methylcellulose, polyethylene
glycol, sodium bicarbonate, shellac, starch, stearic acid, titanium dioxide,
and vanillin. Dyes in the form of aluminum lakes are contained in each tablet
strength as follows: 0.3 mg Tablet: FD&C Yellow No. 6, D&C Yellow
No. 10. 0.625 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10.
1.25 mg Tablet: FD&C Yellow No.6, D&C Yellow No.10, FD&C
Blue No.1. 2.5 mg Tablet: D&C Red No.30.Last reviewed on RxList: 10/28/2008





Other reviews about Estrogens on wordpress

[Hormone dysregulators. Pseudo-estrogens in dental composite resins and sealanta?]
  by carlosprimeros
[Article in Dutch] Schuurs AH, Moorer WR. Afdeling Cariologie Endodontologie Pedodontologie, Academisch Centrum Tandheelkunde Amsterdam (ACTA). A number of polluting chemicals in the ecosystems must be characterized as hormone disruptors. Among […]


Estrogens (Not to be confused with Phytoestrogens) in Skincare Show Link to Breast Cancer
  by doshacare
  Alarming reports surface from the Environmental Working Group about estrogens in some high end skincare creams. These reports are causing a stir in the skincare industry and confusing […]


Bye Bye, testes ?
  by loranablog
Do you remember the estrogen mimicking bisphenol (contained in every plastic product we use even for food)? And what about the sex disruption in that Canadian fish population […]


Bioidentical Estrogens Explained
  by thecompounder
In previous blog postings, I've discussed hormones that qualify as bioidentical and the power of progesterone.  Here I want to dig a little deeper into the bioidentical estrogens since they […]


Soy in research news again as possible protection against prostate cancer
  by Jim Tucker
JULY 26: URO TODAY:  High intake of secondary vegetable substances found in soy, called isoflavones, may protect against prostate cancer, according to findings in a study of […]


Anti-estrogens May Offer Protection Against Lung Cancer Mortality
  by AACR Communications Staff
• Anti-estrogen therapy significantly decreased the risk of lung cancer death. • Results support the role of estrogens in lung cancer management. SAN ANTONIO - Anti-estrogens as therapy for breast cancer may […]


Estrogens: Production, Functions and Applications
  by SinlorD
Estrogens: Production, Functions and Applications (Endocrinology Research and Clinical Developments) By James R. Bartos Publisher: Nova Science Publishers […]


Avoid using all the products that contain mimic estrogens...
  by periodvitamin
Women's hormonal health is depending on harmony of progesterone and estrogen. There are many causes for hormonal imbalance but the root of the cause is estrogen dominance. The […]


Estrogens shown to play part in boosting prostate cancer
  by Jim Tucker
URO TODAY: Estrogens play a pivotal role in the development and progression of prostate cancer, and a new study has examined new ways this may happen. READ […]


New study confirms preference of topical estrogens over oral estrogens
  by thecompounder
A recently published study in the journal Circulation looked at the thrombotic risk (i.e. risk of heart attack or stroke due to a blood clot) from oral and […]



Other reviews about Estrogens on web:

Estrogens , oestrogens , or œstrogens, are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone ... Estrogen - Wikipedia, the free encyclopedia


Estrogens are responsible for female sexual development and function, such as breast development and the menstrual cycle. In women, estrogens are produced mainly in the ... Estrogen Hormones (Estradiol, Estriol, and Estrone) and Estrogen Tests


Premarin is the commercial name for compound drug consisting primarily of conjugated estrogens. Isolated from mare's urine (PRE gnant MAR es' ur IN e), it is manufactured by Wyeth ... Premarin - Wikipedia, the free encyclopedia


Explains the medication estrogens conjugated (Premarin), a drug used for treating the symptoms of menopause including hot flashes, vaginal dryness, and vaginal atrophy. estrogens conjugated (Premarin) - drug class, medical uses ...


To search for endogenous estrogens that may have preferential binding affinity for human estrogen receptor (ER) alpha or beta subtype and also to gain insights into the structural ... estrogens - definition of estrogens in the Medical dictionary - by ...


Medical information about Menopause therapies, symptoms and treatment. estrogens (conjugated) and medroxyprogesterone - Menopause ...


Estrogens (AmE), oestrogens (BE), or œstrogens, are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex ... Estrogens - Kosmix : Reference, Videos, Images, News, Shopping and ...


Conjugated equine estrogens have been used most commonly in the United States, and most of the large epidemiological studies have been done with this form of oral estrogen. Estrogen


estrogens (es′trō-jenz) n.pl The collective term for substances capable of producing estrus. The term also applies to the estrogenic hormones in women estrogens: Definition from Answers.com


–noun Biochemistry. any of several major female sex hormones produced primarily by the ovarian follicles of female mammals, capable of inducing estrus, developing and maintaining ... Estrogens | Define Estrogens at Dictionary.com





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