Reviews Enalapril Maleate-Felodipine


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Lexxel Drug Description
LEXXEL®
(enalapril maleate-felodipine ER) Tablets

USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, LEXXEL should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION



What are the possible side effects of enalapril and felodipine (Lexxel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
chest pain;
swelling in your hands or feet;
fast, pounding, or uneven heartbeats;
fever, chills, body aches, flu symptoms; or
nausea,...
Read All Potential Side Effects for Lexxel »




LEXXEL (enalapril maleate-felodipine ER) is a combination product, consisting of an outer layer of enalapril maleate surrounding a core tablet of an extended-release felodipine formulation.
Enalapril maleate is the maleate salt of enalapril, the ethyl ester of a long-acting
angiotensin converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically
described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L- alanyl]-L-proline,
(Z)-2-butenedioate salt (1:1). Its empirical formula is C20H28N2O5•C4H4O4,
and its structural formula is:







Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.
Felodipine, a calcium channel blocker, is a dihydropyridine derivative that
is chemically described as ± ethyl methyl 4- (2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-
pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4
and its structural formula is:







Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture; however, S-felodipine is the more biologically active enantiomer.
LEXXEL is available for oral use as tablets containing 5 mg of enalapril maleate and 5 mg of felodipine as an extended release formulation.
Inactive ingredients include: propyl gallate, polyoxyl 40 hydrogenated castor oil, cellulose compounds, lactose, aluminum silicate, sodium stearyl fumarate, carnauba wax, and black iron oxide. The tablets are imprinted with an ink of synthetic black iron oxide which contains pharmaceutical glaze in SD-45, n-butyl alcohol, propylene glycol, isopropyl alcohol, ammonium hydroxide, and methyl alcohol.
Last reviewed on RxList: 10/25/2007




Lexxel Drug Description
LEXXEL®
(enalapril maleate-felodipine ER) Tablets

USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, LEXXEL should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION



What are the possible side effects of enalapril and felodipine (Lexxel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
chest pain;
swelling in your hands or feet;
fast, pounding, or uneven heartbeats;
fever, chills, body aches, flu symptoms; or
nausea,...
Read All Potential Side Effects for Lexxel »




LEXXEL (enalapril maleate-felodipine ER) is a combination product, consisting of an outer layer of enalapril maleate surrounding a core tablet of an extended-release felodipine formulation.
Enalapril maleate is the maleate salt of enalapril, the ethyl ester of a long-acting
angiotensin converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically
described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L- alanyl]-L-proline,
(Z)-2-butenedioate salt (1:1). Its empirical formula is C20H28N2O5•C4H4O4,
and its structural formula is:







Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.
Felodipine, a calcium channel blocker, is a dihydropyridine derivative that
is chemically described as ± ethyl methyl 4- (2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-
pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4
and its structural formula is:







Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture; however, S-felodipine is the more biologically active enantiomer.
LEXXEL is available for oral use as tablets containing 5 mg of enalapril maleate and 5 mg of felodipine as an extended release formulation.
Inactive ingredients include: propyl gallate, polyoxyl 40 hydrogenated castor oil, cellulose compounds, lactose, aluminum silicate, sodium stearyl fumarate, carnauba wax, and black iron oxide. The tablets are imprinted with an ink of synthetic black iron oxide which contains pharmaceutical glaze in SD-45, n-butyl alcohol, propylene glycol, isopropyl alcohol, ammonium hydroxide, and methyl alcohol.
Last reviewed on RxList: 10/25/2007




Lexxel Drug Description
LEXXEL®
(enalapril maleate-felodipine ER) Tablets

USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, LEXXEL should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION



What are the possible side effects of enalapril and felodipine (Lexxel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
chest pain;
swelling in your hands or feet;
fast, pounding, or uneven heartbeats;
fever, chills, body aches, flu symptoms; or
nausea,...
Read All Potential Side Effects for Lexxel »




LEXXEL (enalapril maleate-felodipine ER) is a combination product, consisting of an outer layer of enalapril maleate surrounding a core tablet of an extended-release felodipine formulation.
Enalapril maleate is the maleate salt of enalapril, the ethyl ester of a long-acting
angiotensin converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically
described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L- alanyl]-L-proline,
(Z)-2-butenedioate salt (1:1). Its empirical formula is C20H28N2O5•C4H4O4,
and its structural formula is:







Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.
Felodipine, a calcium channel blocker, is a dihydropyridine derivative that
is chemically described as ± ethyl methyl 4- (2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-
pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4
and its structural formula is:







Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture; however, S-felodipine is the more biologically active enantiomer.
LEXXEL is available for oral use as tablets containing 5 mg of enalapril maleate and 5 mg of felodipine as an extended release formulation.
Inactive ingredients include: propyl gallate, polyoxyl 40 hydrogenated castor oil, cellulose compounds, lactose, aluminum silicate, sodium stearyl fumarate, carnauba wax, and black iron oxide. The tablets are imprinted with an ink of synthetic black iron oxide which contains pharmaceutical glaze in SD-45, n-butyl alcohol, propylene glycol, isopropyl alcohol, ammonium hydroxide, and methyl alcohol.
Last reviewed on RxList: 10/25/2007




Lexxel Drug Description
LEXXEL®
(enalapril maleate-felodipine ER) Tablets

USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, LEXXEL should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION



What are the possible side effects of enalapril and felodipine (Lexxel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
chest pain;
swelling in your hands or feet;
fast, pounding, or uneven heartbeats;
fever, chills, body aches, flu symptoms; or
nausea,...
Read All Potential Side Effects for Lexxel »




LEXXEL (enalapril maleate-felodipine ER) is a combination product, consisting of an outer layer of enalapril maleate surrounding a core tablet of an extended-release felodipine formulation.
Enalapril maleate is the maleate salt of enalapril, the ethyl ester of a long-acting
angiotensin converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically
described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L- alanyl]-L-proline,
(Z)-2-butenedioate salt (1:1). Its empirical formula is C20H28N2O5•C4H4O4,
and its structural formula is:







Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.
Felodipine, a calcium channel blocker, is a dihydropyridine derivative that
is chemically described as ± ethyl methyl 4- (2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-
pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4
and its structural formula is:







Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture; however, S-felodipine is the more biologically active enantiomer.
LEXXEL is available for oral use as tablets containing 5 mg of enalapril maleate and 5 mg of felodipine as an extended release formulation.
Inactive ingredients include: propyl gallate, polyoxyl 40 hydrogenated castor oil, cellulose compounds, lactose, aluminum silicate, sodium stearyl fumarate, carnauba wax, and black iron oxide. The tablets are imprinted with an ink of synthetic black iron oxide which contains pharmaceutical glaze in SD-45, n-butyl alcohol, propylene glycol, isopropyl alcohol, ammonium hydroxide, and methyl alcohol.
Last reviewed on RxList: 10/25/2007




Lexxel Drug Description
LEXXEL®
(enalapril maleate-felodipine ER) Tablets

USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, LEXXEL should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION



What are the possible side effects of enalapril and felodipine (Lexxel)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
chest pain;
swelling in your hands or feet;
fast, pounding, or uneven heartbeats;
fever, chills, body aches, flu symptoms; or
nausea,...
Read All Potential Side Effects for Lexxel »




LEXXEL (enalapril maleate-felodipine ER) is a combination product, consisting of an outer layer of enalapril maleate surrounding a core tablet of an extended-release felodipine formulation.
Enalapril maleate is the maleate salt of enalapril, the ethyl ester of a long-acting
angiotensin converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically
described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L- alanyl]-L-proline,
(Z)-2-butenedioate salt (1:1). Its empirical formula is C20H28N2O5•C4H4O4,
and its structural formula is:







Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.
Felodipine, a calcium channel blocker, is a dihydropyridine derivative that
is chemically described as ± ethyl methyl 4- (2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-
pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4
and its structural formula is:







Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture; however, S-felodipine is the more biologically active enantiomer.
LEXXEL is available for oral use as tablets containing 5 mg of enalapril maleate and 5 mg of felodipine as an extended release formulation.
Inactive ingredients include: propyl gallate, polyoxyl 40 hydrogenated castor oil, cellulose compounds, lactose, aluminum silicate, sodium stearyl fumarate, carnauba wax, and black iron oxide. The tablets are imprinted with an ink of synthetic black iron oxide which contains pharmaceutical glaze in SD-45, n-butyl alcohol, propylene glycol, isopropyl alcohol, ammonium hydroxide, and methyl alcohol.
Last reviewed on RxList: 10/25/2007





Other reviews about Enalapril Maleate-Felodipine on web:

Learn about the prescription medication Lexxel (Enalapril Maleate-Felodipine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Lexxel (Enalapril Maleate-Felodipine) Drug Information: Uses, Side ...


Enalapril Maleate/Felodipine professional patient advice. Specific and up to date information about Enalapril Maleate/Felodipine. Complete Enalapril Maleate/Felodipine information from Drugs.com


Comprehensive and trusted information about Enalapril maleate, Felodipine - plus advice on 24,000 other FDA approved drugs and medications from Drugs.com. Enalapril maleate, Felodipine patient advice including side effects


Find patient medical information for Enalapril Maleate-Felodipine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Enalapril Maleate-Felodipine Oral : Uses, Side Effects ...


Enalapril Maleate, Felodipine Oral tablet, extended-release To return to the main entry click here . What is this medicine? ENALAPRIL; FELODIPINE (e Enalapril Maleate, Felodipine Oral tablet, extended-release ...


Dietary Advice Enalapril maleate/felodipine is best taken without food. The drug can, however, be taken with grapefruit juice. Reference Library | WholeHealthMD


Rate Enalapril maleate + Felodipine to receive MedCheck, Discover best treatments based on user reviews of side effects, efficacy, health benefits, uses, safety and medical advice Enalapril maleate + Felodipine Survey. Reviews and Patient ...


Learn about Enalapril Maleate-Felodipine Oral - its uses, dosage, side effects, drug interactions, and safety information on RxList. Enalapril Maleate-Felodipine Oral Drug information on Uses, Side ...


LEXXEL ® (enalapril maleate-felodipine ER) TABLETS USE IN PREGNANCY When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the ... enalapril maleate-felodipine er


Enalapril Maleate, Felodipine Oral tablet, extended-release What is this medicine? ENALAPRIL; FELODIPINE (e NAL a pril; fe LOE di peen) is a combination of two drugs. Enalapril; Felodipine





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