Reviews Dynacirc CR


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Dynacirc CR Drug Description
DynaCirc CR®
(isradipine) Controlled Release Tablets
DRUG DESCRIPTION



What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
feeling short of breath, even with mild exertion;
swelling in your hands and feet;
fast or pounding heartbeats; or
chest pain.

Less serious side effects...
Read All Potential Side Effects for Dynacirc CR »




DynaCirc CR® contains isradipine, a calcium antagonist. It is available for once-daily oral administration as a controlled release 5 mg and 10 mg tablet for DynaCirc CR® (isradipine). DynaCirc CR® is a registered trademark for isradipine GITS (Gastrointestinal Therapeutic System) tablets.
The structural formula of isradipine is:








Chemically, isradipine is 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester. Isradipine is a yellow, fine crystalline powder which is odorless or has a faint characteristic odor. Isradipine is practically insoluble in water ( < 10 mg/L at 37°C), but is soluble in ethanol and freely soluble in acetone,chloroform and methylene chloride.
Active Ingredient: isradipine
Inactive Ingredients: butylated hydroxytoluene; cellulose acetate;
hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene
oxide; polysorbate 80; propylene glycol; red ferric oxide; silicon dioxide;
sodium chloride; titanium dioxide; yellow ferric oxide.
System Components and Performance
Isradipine is delivered from the DynaCirc CR® (isradipine) Controlled Release
Tablet as follows: a semipermeable membrane surrounds an osmotically active
drug core.The core is composed of two layers: an "active"layer containing
the drug, and a pharmacologically inert but osmotically active "push"
layer. After ingestion, the tablet overcoating is quickly dissipated in the
gastrointestinal tract,allowing water to enter the tablet through the semipermeable
membrane. The polyethylene oxide polymer swells in the osmotic ("push")
layer and exerts pressure against the "active"drug layer, releasing
isradipine as a fine suspension through the laser-drilled tablet orifice which
has been positioned on the "active" drug layer side. Drug delivery
is essentially constant as long as the osmotic gradient remains constant and,
after either 5 mg or 10 mg of isradipine is released, gradually falls to a negligible
amount.The controlled rate of drug delivery into the gastrointestinal lumen
is independent of pH or gastrointestinal motility. The delivery of isradipine
in DynaCirc CR® (isradipine) Controlled Release Tablets depends on the existence
of an osmotic gradient between the contents of the bilayer core and the fluid
in the GI tract.The biologically inert core of the tablet remains intact and,unless
it becomes trapped, is eliminated in the feces.Last reviewed on RxList: 12/30/2008




Dynacirc CR Drug Description
DynaCirc CR®
(isradipine) Controlled Release Tablets
DRUG DESCRIPTION



What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
feeling short of breath, even with mild exertion;
swelling in your hands and feet;
fast or pounding heartbeats; or
chest pain.

Less serious side effects...
Read All Potential Side Effects for Dynacirc CR »




DynaCirc CR® contains isradipine, a calcium antagonist. It is available for once-daily oral administration as a controlled release 5 mg and 10 mg tablet for DynaCirc CR® (isradipine). DynaCirc CR® is a registered trademark for isradipine GITS (Gastrointestinal Therapeutic System) tablets.
The structural formula of isradipine is:








Chemically, isradipine is 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester. Isradipine is a yellow, fine crystalline powder which is odorless or has a faint characteristic odor. Isradipine is practically insoluble in water ( < 10 mg/L at 37°C), but is soluble in ethanol and freely soluble in acetone,chloroform and methylene chloride.
Active Ingredient: isradipine
Inactive Ingredients: butylated hydroxytoluene; cellulose acetate;
hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene
oxide; polysorbate 80; propylene glycol; red ferric oxide; silicon dioxide;
sodium chloride; titanium dioxide; yellow ferric oxide.
System Components and Performance
Isradipine is delivered from the DynaCirc CR® (isradipine) Controlled Release
Tablet as follows: a semipermeable membrane surrounds an osmotically active
drug core.The core is composed of two layers: an "active"layer containing
the drug, and a pharmacologically inert but osmotically active "push"
layer. After ingestion, the tablet overcoating is quickly dissipated in the
gastrointestinal tract,allowing water to enter the tablet through the semipermeable
membrane. The polyethylene oxide polymer swells in the osmotic ("push")
layer and exerts pressure against the "active"drug layer, releasing
isradipine as a fine suspension through the laser-drilled tablet orifice which
has been positioned on the "active" drug layer side. Drug delivery
is essentially constant as long as the osmotic gradient remains constant and,
after either 5 mg or 10 mg of isradipine is released, gradually falls to a negligible
amount.The controlled rate of drug delivery into the gastrointestinal lumen
is independent of pH or gastrointestinal motility. The delivery of isradipine
in DynaCirc CR® (isradipine) Controlled Release Tablets depends on the existence
of an osmotic gradient between the contents of the bilayer core and the fluid
in the GI tract.The biologically inert core of the tablet remains intact and,unless
it becomes trapped, is eliminated in the feces.Last reviewed on RxList: 12/30/2008




Dynacirc CR Drug Description
DynaCirc CR®
(isradipine) Controlled Release Tablets
DRUG DESCRIPTION



What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
feeling short of breath, even with mild exertion;
swelling in your hands and feet;
fast or pounding heartbeats; or
chest pain.

Less serious side effects...
Read All Potential Side Effects for Dynacirc CR »




DynaCirc CR® contains isradipine, a calcium antagonist. It is available for once-daily oral administration as a controlled release 5 mg and 10 mg tablet for DynaCirc CR® (isradipine). DynaCirc CR® is a registered trademark for isradipine GITS (Gastrointestinal Therapeutic System) tablets.
The structural formula of isradipine is:








Chemically, isradipine is 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester. Isradipine is a yellow, fine crystalline powder which is odorless or has a faint characteristic odor. Isradipine is practically insoluble in water ( < 10 mg/L at 37°C), but is soluble in ethanol and freely soluble in acetone,chloroform and methylene chloride.
Active Ingredient: isradipine
Inactive Ingredients: butylated hydroxytoluene; cellulose acetate;
hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene
oxide; polysorbate 80; propylene glycol; red ferric oxide; silicon dioxide;
sodium chloride; titanium dioxide; yellow ferric oxide.
System Components and Performance
Isradipine is delivered from the DynaCirc CR® (isradipine) Controlled Release
Tablet as follows: a semipermeable membrane surrounds an osmotically active
drug core.The core is composed of two layers: an "active"layer containing
the drug, and a pharmacologically inert but osmotically active "push"
layer. After ingestion, the tablet overcoating is quickly dissipated in the
gastrointestinal tract,allowing water to enter the tablet through the semipermeable
membrane. The polyethylene oxide polymer swells in the osmotic ("push")
layer and exerts pressure against the "active"drug layer, releasing
isradipine as a fine suspension through the laser-drilled tablet orifice which
has been positioned on the "active" drug layer side. Drug delivery
is essentially constant as long as the osmotic gradient remains constant and,
after either 5 mg or 10 mg of isradipine is released, gradually falls to a negligible
amount.The controlled rate of drug delivery into the gastrointestinal lumen
is independent of pH or gastrointestinal motility. The delivery of isradipine
in DynaCirc CR® (isradipine) Controlled Release Tablets depends on the existence
of an osmotic gradient between the contents of the bilayer core and the fluid
in the GI tract.The biologically inert core of the tablet remains intact and,unless
it becomes trapped, is eliminated in the feces.Last reviewed on RxList: 12/30/2008




Dynacirc CR Drug Description
DynaCirc CR®
(isradipine) Controlled Release Tablets
DRUG DESCRIPTION



What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
feeling short of breath, even with mild exertion;
swelling in your hands and feet;
fast or pounding heartbeats; or
chest pain.

Less serious side effects...
Read All Potential Side Effects for Dynacirc CR »




DynaCirc CR® contains isradipine, a calcium antagonist. It is available for once-daily oral administration as a controlled release 5 mg and 10 mg tablet for DynaCirc CR® (isradipine). DynaCirc CR® is a registered trademark for isradipine GITS (Gastrointestinal Therapeutic System) tablets.
The structural formula of isradipine is:








Chemically, isradipine is 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester. Isradipine is a yellow, fine crystalline powder which is odorless or has a faint characteristic odor. Isradipine is practically insoluble in water ( < 10 mg/L at 37°C), but is soluble in ethanol and freely soluble in acetone,chloroform and methylene chloride.
Active Ingredient: isradipine
Inactive Ingredients: butylated hydroxytoluene; cellulose acetate;
hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene
oxide; polysorbate 80; propylene glycol; red ferric oxide; silicon dioxide;
sodium chloride; titanium dioxide; yellow ferric oxide.
System Components and Performance
Isradipine is delivered from the DynaCirc CR® (isradipine) Controlled Release
Tablet as follows: a semipermeable membrane surrounds an osmotically active
drug core.The core is composed of two layers: an "active"layer containing
the drug, and a pharmacologically inert but osmotically active "push"
layer. After ingestion, the tablet overcoating is quickly dissipated in the
gastrointestinal tract,allowing water to enter the tablet through the semipermeable
membrane. The polyethylene oxide polymer swells in the osmotic ("push")
layer and exerts pressure against the "active"drug layer, releasing
isradipine as a fine suspension through the laser-drilled tablet orifice which
has been positioned on the "active" drug layer side. Drug delivery
is essentially constant as long as the osmotic gradient remains constant and,
after either 5 mg or 10 mg of isradipine is released, gradually falls to a negligible
amount.The controlled rate of drug delivery into the gastrointestinal lumen
is independent of pH or gastrointestinal motility. The delivery of isradipine
in DynaCirc CR® (isradipine) Controlled Release Tablets depends on the existence
of an osmotic gradient between the contents of the bilayer core and the fluid
in the GI tract.The biologically inert core of the tablet remains intact and,unless
it becomes trapped, is eliminated in the feces.Last reviewed on RxList: 12/30/2008




Dynacirc CR Drug Description
DynaCirc CR®
(isradipine) Controlled Release Tablets
DRUG DESCRIPTION



What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

feeling like you might pass out;
feeling short of breath, even with mild exertion;
swelling in your hands and feet;
fast or pounding heartbeats; or
chest pain.

Less serious side effects...
Read All Potential Side Effects for Dynacirc CR »




DynaCirc CR® contains isradipine, a calcium antagonist. It is available for once-daily oral administration as a controlled release 5 mg and 10 mg tablet for DynaCirc CR® (isradipine). DynaCirc CR® is a registered trademark for isradipine GITS (Gastrointestinal Therapeutic System) tablets.
The structural formula of isradipine is:








Chemically, isradipine is 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester. Isradipine is a yellow, fine crystalline powder which is odorless or has a faint characteristic odor. Isradipine is practically insoluble in water ( < 10 mg/L at 37°C), but is soluble in ethanol and freely soluble in acetone,chloroform and methylene chloride.
Active Ingredient: isradipine
Inactive Ingredients: butylated hydroxytoluene; cellulose acetate;
hydroxypropyl methylcellulose; magnesium stearate; polyethylene glycol; polyethylene
oxide; polysorbate 80; propylene glycol; red ferric oxide; silicon dioxide;
sodium chloride; titanium dioxide; yellow ferric oxide.
System Components and Performance
Isradipine is delivered from the DynaCirc CR® (isradipine) Controlled Release
Tablet as follows: a semipermeable membrane surrounds an osmotically active
drug core.The core is composed of two layers: an "active"layer containing
the drug, and a pharmacologically inert but osmotically active "push"
layer. After ingestion, the tablet overcoating is quickly dissipated in the
gastrointestinal tract,allowing water to enter the tablet through the semipermeable
membrane. The polyethylene oxide polymer swells in the osmotic ("push")
layer and exerts pressure against the "active"drug layer, releasing
isradipine as a fine suspension through the laser-drilled tablet orifice which
has been positioned on the "active" drug layer side. Drug delivery
is essentially constant as long as the osmotic gradient remains constant and,
after either 5 mg or 10 mg of isradipine is released, gradually falls to a negligible
amount.The controlled rate of drug delivery into the gastrointestinal lumen
is independent of pH or gastrointestinal motility. The delivery of isradipine
in DynaCirc CR® (isradipine) Controlled Release Tablets depends on the existence
of an osmotic gradient between the contents of the bilayer core and the fluid
in the GI tract.The biologically inert core of the tablet remains intact and,unless
it becomes trapped, is eliminated in the feces.Last reviewed on RxList: 12/30/2008





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Other reviews about Dynacirc CR on web:

PRESCRIBING INFORMATION DYNACIRC CR ® (isradipine) Controlled Release Tablets DESCRIPTION DYNACIRC CR contains isradipine, a calcium antagonist. It is available for once-daily oral ... DYNACIRC CR prescribing information


Learn about the prescription medication Dynacirc CR (Isradipine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Dynacirc CR (Isradipine) Drug Information: Uses, Side Effects ...


All about DynaCirc CR Extended-Release Tablets. View complete and up to date DynaCirc CR information - part of the Drugs.com trusted medication database. DynaCirc CR Extended-Release Tablets Facts and Comparisons at ...


Accurate, FDA approved DynaCirc CR information for healthcare professionals and patients - brought to you by Drugs.com. DynaCirc CR Official FDA information, side effects and uses.


Dynacirc CR is a prescription drug that is used for controlling high blood pressure. This part of the eMedTV archives describes Dynacirc CR in more detail and offers information on ... Dynacirc CR


What are the possible side effects of isradipine (Dynacirc, Dynacirc CR)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty ... Dynacirc (Isradipine) Drug Information: Uses, Side Effects, Drug ...


Since blood pressure declines gradually, it may be several weeks before you get the full benefit of DynaCirc CR; continue taking it even if you are feeling well. DynaCirc | Prescription Drug Information, Side Effects | PDRHealth


DynaCirc CR is a calcium channel blocker used to treat high blood pressure. Side effects and interactions are available at drugstore.com; plus get home delivery from a trusted and ... DynaCirc CR - drugstore.com. Low prices, side effects, interactions.


Important Note: The Following Information Is Intended To Supplement, Not Substitute For, The Expertise And Judgment Of Your Physician, Pharmacist Or Other Healthcare Professional. DYNACIRC CR Patient Assistance Program


Dynacirc Cr (isradipine) 5mg is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart ... Buy Dynacirc Cr (isradipine) 5mg Tablet Online





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