Reviews Dornase alfa


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Pulmozyme Drug Description
Pulmozyme®
(dornase alfa) Inhalation Solution
DRUG DESCRIPTION



What are the possible side effects of dornase alfa (Pulmozyme)?

If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
increased difficulty breathing;
chest pain; or
fever.

Less serious side effects may be more likely to occur with the use of dornase alfa. Talk to your doctor if you experience...
Read All Potential Side Effects for Pulmozyme »




Pulmozyme® (dornase alfa) Inhalation Solution is a sterile, clear, colorless,
highly purified solution of recombinant human deoxyribonuclease I (rhDNase),
an enzyme which selectively cleaves DNA. The protein is produced by genetically
engineered Chinese Hamster Ovary (CHO) cells containing DNA encoding for the
native human protein, deoxyribonuclease I (DNase). Fermentation is carried out
in a nutrient medium containing the antibiotic gentamicin, 100-200 mg/L. However,
the presence of the antibiotic is not detectable in the final product. The product
is purified by tangential flow filtration and column chromatography. The purified
glycoprotein contains 260 amino acids with an approximate molecular weight of
37,000 daltons1. The primary amino acid sequence is identical to
that of the native human enzyme.
Pulmozyme is administered by inhalation of an aerosol mist produced by a compressed
air driven nebulizer system (see Clinical Experience,
DOSAGE AND ADMINISTRATION). Each Pulmozyme
single-use ampule will deliver 2.5 mL of the solution to the nebulizer bowl.
The aqueous solution contains 1.0 mg/mL dornase alfa, 0.15 mg/mL calcium chloride
dihydrate and 8.77 mg/mL sodium chloride. The solution contains no preservative.
The nominal pH of the solution is 6.3.Last reviewed on RxList: 12/16/2008




Pulmozyme Drug Description
Pulmozyme®
(dornase alfa) Inhalation Solution
DRUG DESCRIPTION



What are the possible side effects of dornase alfa (Pulmozyme)?

If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
increased difficulty breathing;
chest pain; or
fever.

Less serious side effects may be more likely to occur with the use of dornase alfa. Talk to your doctor if you experience...
Read All Potential Side Effects for Pulmozyme »




Pulmozyme® (dornase alfa) Inhalation Solution is a sterile, clear, colorless,
highly purified solution of recombinant human deoxyribonuclease I (rhDNase),
an enzyme which selectively cleaves DNA. The protein is produced by genetically
engineered Chinese Hamster Ovary (CHO) cells containing DNA encoding for the
native human protein, deoxyribonuclease I (DNase). Fermentation is carried out
in a nutrient medium containing the antibiotic gentamicin, 100-200 mg/L. However,
the presence of the antibiotic is not detectable in the final product. The product
is purified by tangential flow filtration and column chromatography. The purified
glycoprotein contains 260 amino acids with an approximate molecular weight of
37,000 daltons1. The primary amino acid sequence is identical to
that of the native human enzyme.
Pulmozyme is administered by inhalation of an aerosol mist produced by a compressed
air driven nebulizer system (see Clinical Experience,
DOSAGE AND ADMINISTRATION). Each Pulmozyme
single-use ampule will deliver 2.5 mL of the solution to the nebulizer bowl.
The aqueous solution contains 1.0 mg/mL dornase alfa, 0.15 mg/mL calcium chloride
dihydrate and 8.77 mg/mL sodium chloride. The solution contains no preservative.
The nominal pH of the solution is 6.3.Last reviewed on RxList: 12/16/2008




Pulmozyme Drug Description
Pulmozyme®
(dornase alfa) Inhalation Solution
DRUG DESCRIPTION



What are the possible side effects of dornase alfa (Pulmozyme)?

If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
increased difficulty breathing;
chest pain; or
fever.

Less serious side effects may be more likely to occur with the use of dornase alfa. Talk to your doctor if you experience...
Read All Potential Side Effects for Pulmozyme »




Pulmozyme® (dornase alfa) Inhalation Solution is a sterile, clear, colorless,
highly purified solution of recombinant human deoxyribonuclease I (rhDNase),
an enzyme which selectively cleaves DNA. The protein is produced by genetically
engineered Chinese Hamster Ovary (CHO) cells containing DNA encoding for the
native human protein, deoxyribonuclease I (DNase). Fermentation is carried out
in a nutrient medium containing the antibiotic gentamicin, 100-200 mg/L. However,
the presence of the antibiotic is not detectable in the final product. The product
is purified by tangential flow filtration and column chromatography. The purified
glycoprotein contains 260 amino acids with an approximate molecular weight of
37,000 daltons1. The primary amino acid sequence is identical to
that of the native human enzyme.
Pulmozyme is administered by inhalation of an aerosol mist produced by a compressed
air driven nebulizer system (see Clinical Experience,
DOSAGE AND ADMINISTRATION). Each Pulmozyme
single-use ampule will deliver 2.5 mL of the solution to the nebulizer bowl.
The aqueous solution contains 1.0 mg/mL dornase alfa, 0.15 mg/mL calcium chloride
dihydrate and 8.77 mg/mL sodium chloride. The solution contains no preservative.
The nominal pH of the solution is 6.3.Last reviewed on RxList: 12/16/2008




Pulmozyme Drug Description
Pulmozyme®
(dornase alfa) Inhalation Solution
DRUG DESCRIPTION



What are the possible side effects of dornase alfa (Pulmozyme)?

If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
increased difficulty breathing;
chest pain; or
fever.

Less serious side effects may be more likely to occur with the use of dornase alfa. Talk to your doctor if you experience...
Read All Potential Side Effects for Pulmozyme »




Pulmozyme® (dornase alfa) Inhalation Solution is a sterile, clear, colorless,
highly purified solution of recombinant human deoxyribonuclease I (rhDNase),
an enzyme which selectively cleaves DNA. The protein is produced by genetically
engineered Chinese Hamster Ovary (CHO) cells containing DNA encoding for the
native human protein, deoxyribonuclease I (DNase). Fermentation is carried out
in a nutrient medium containing the antibiotic gentamicin, 100-200 mg/L. However,
the presence of the antibiotic is not detectable in the final product. The product
is purified by tangential flow filtration and column chromatography. The purified
glycoprotein contains 260 amino acids with an approximate molecular weight of
37,000 daltons1. The primary amino acid sequence is identical to
that of the native human enzyme.
Pulmozyme is administered by inhalation of an aerosol mist produced by a compressed
air driven nebulizer system (see Clinical Experience,
DOSAGE AND ADMINISTRATION). Each Pulmozyme
single-use ampule will deliver 2.5 mL of the solution to the nebulizer bowl.
The aqueous solution contains 1.0 mg/mL dornase alfa, 0.15 mg/mL calcium chloride
dihydrate and 8.77 mg/mL sodium chloride. The solution contains no preservative.
The nominal pH of the solution is 6.3.Last reviewed on RxList: 12/16/2008




Pulmozyme Drug Description
Pulmozyme®
(dornase alfa) Inhalation Solution
DRUG DESCRIPTION



What are the possible side effects of dornase alfa (Pulmozyme)?

If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
increased difficulty breathing;
chest pain; or
fever.

Less serious side effects may be more likely to occur with the use of dornase alfa. Talk to your doctor if you experience...
Read All Potential Side Effects for Pulmozyme »




Pulmozyme® (dornase alfa) Inhalation Solution is a sterile, clear, colorless,
highly purified solution of recombinant human deoxyribonuclease I (rhDNase),
an enzyme which selectively cleaves DNA. The protein is produced by genetically
engineered Chinese Hamster Ovary (CHO) cells containing DNA encoding for the
native human protein, deoxyribonuclease I (DNase). Fermentation is carried out
in a nutrient medium containing the antibiotic gentamicin, 100-200 mg/L. However,
the presence of the antibiotic is not detectable in the final product. The product
is purified by tangential flow filtration and column chromatography. The purified
glycoprotein contains 260 amino acids with an approximate molecular weight of
37,000 daltons1. The primary amino acid sequence is identical to
that of the native human enzyme.
Pulmozyme is administered by inhalation of an aerosol mist produced by a compressed
air driven nebulizer system (see Clinical Experience,
DOSAGE AND ADMINISTRATION). Each Pulmozyme
single-use ampule will deliver 2.5 mL of the solution to the nebulizer bowl.
The aqueous solution contains 1.0 mg/mL dornase alfa, 0.15 mg/mL calcium chloride
dihydrate and 8.77 mg/mL sodium chloride. The solution contains no preservative.
The nominal pH of the solution is 6.3.Last reviewed on RxList: 12/16/2008





Other reviews about Dornase alfa on wordpress

CYSTIC FIBROSIS
  by vanithagohi
                             MEANING:   Cystic fibrosis is a disease which is characterized by the production of abnormally viscous mucus by the affected glands, usually resulting in chronic respiratory infections and impaired […]


BioFocus DPI's innovative target discovery platform is poised to deliver promising targets for the treatment of cystic fibrosis
  by weiminson
There is still a pressing need for new treatments for cystic fibrosis. Despite nearly two decades of research since the discovery of the defective gene underlying the disease, […]



Other reviews about Dornase alfa on web:

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa - Wikipedia, the free encyclopedia


Learn about the prescription medication Pulmozyme (Dornase alfa), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Pulmozyme (Dornase alfa) Drug Information: Uses, Side Effects ...


dornase alfa ( ) n. A genetically engineered enzyme used to hydrolyze the DNA in bronchial mucus, facilitating its expectoration, in the treatment of dornase alfa: Definition from Answers.com


Pulmozyme (dornase alfa) - Find information about Cystic Fibrosis: its symptoms, treatment, and about Pulmozyme (dornase alfa) Inhalation Solution. Cystic Fibrosis Treatment Information - Pulmozyme (dornase alfa)


dornase alfa Inhalation, oral/nebulization patient information. Detailed drug information for the consumer, includes dosage, dornase alfa Inhalation, oral/nebulization side effects ... dornase alfa Inhalation, oral/nebulization consumer information ...


Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways ... Dornase Alfa: MedlinePlus Drug Information


All about Dornase Alfa. View complete and up to date Dornase Alfa information - part of the Drugs.com trusted medication database. Dornase Alfa Facts and Comparisons at Drugs.com


Dornase alfa is a drug used to improve lung function in people with cystic fibrosis. This eMedTV segment takes an in-depth look at the drug, explaining how it works, possible side ... Dornase Alfa


If you begin coughing during treatment, turn off the nebulizer taking care not to spill the drug. You can resume treatment when coughing stops. Do not dilute dornase alfa or use ... Reference Library | WholeHealthMD


dornase alfa /dor·nase al·fa/ (dor´nāz al´fah) recombinant human deoxyribonuclease I (DNase I) used to reduce the viscosity of sputum in cystic fibrosis. dornase alfa - definition of dornase alfa in the Medical ...





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