Reviews Desflurane


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Suprane Drug Description
Suprane
(desflurane, USP) Volatile Liquid for Inhalation
DRUG DESCRIPTION
SUPRANE, a nonflammable liquid administered via vaporizer, is a general inhalation anesthetic. It is (±)1,2,2,2-tetrafluoroethyl difluoromethyl ether:
Some physical constants are:








Some physical constants are:



Molecular weight
168.04


Specific gravity (at 20°C/4°C)
1.465


Vapor pressure in mm Hg
669 mm Hg @ 20°C


 
731 mm Hg @ 22°C


 
757 mm Hg @


 
22.8°C (boiling point;1atm)


 
764 mm Hg @ 23°C


 
798 mm Hg @ 24°C


 
869 mm Hg @ 26°C



Partition coefficients at 37°C:



Blood/Gas
0.424


Olive Oil/Gas
18.7


Brain/Gas
0.54



Mean Component/Gas Partition Coefficients:



Polypropylene (Y piece)
6.7


Polyethylene (circuit tube)
16.2


Latex rubber (bag)
19.3


Latex rubber (bellows)
10.4


Polyvinylchloride
34.7


(endotracheal tube)
 



SUPRANE is nonflammable as defined by the requirements of International Electrotechnical
Commission 601-2-13.
SUPRANE is a colorless, volatile liquid below 22.8°C. Data indicate that SUPRANE is stable when stored under normal room lighting conditions according to instructions.
SUPRANE is chemically stable. The only known degradation reaction is through prolonged direct contact with soda lime producing low levels of fluoroform (CHF3). The amount of CHF3 obtained is similar to that produced with MAC-equivalent doses of isoflurane. No discernible degradation occurs in the presence of strong acids.
SUPRANE does not corrode stainless steel, brass, aluminum, anodized aluminum, nickel plated brass, copper, or beryllium.
Last reviewed on RxList: 4/27/2010




Suprane Drug Description
Suprane
(desflurane, USP) Volatile Liquid for Inhalation
DRUG DESCRIPTION
SUPRANE, a nonflammable liquid administered via vaporizer, is a general inhalation anesthetic. It is (±)1,2,2,2-tetrafluoroethyl difluoromethyl ether:
Some physical constants are:








Some physical constants are:



Molecular weight
168.04


Specific gravity (at 20°C/4°C)
1.465


Vapor pressure in mm Hg
669 mm Hg @ 20°C


 
731 mm Hg @ 22°C


 
757 mm Hg @


 
22.8°C (boiling point;1atm)


 
764 mm Hg @ 23°C


 
798 mm Hg @ 24°C


 
869 mm Hg @ 26°C



Partition coefficients at 37°C:



Blood/Gas
0.424


Olive Oil/Gas
18.7


Brain/Gas
0.54



Mean Component/Gas Partition Coefficients:



Polypropylene (Y piece)
6.7


Polyethylene (circuit tube)
16.2


Latex rubber (bag)
19.3


Latex rubber (bellows)
10.4


Polyvinylchloride
34.7


(endotracheal tube)
 



SUPRANE is nonflammable as defined by the requirements of International Electrotechnical
Commission 601-2-13.
SUPRANE is a colorless, volatile liquid below 22.8°C. Data indicate that SUPRANE is stable when stored under normal room lighting conditions according to instructions.
SUPRANE is chemically stable. The only known degradation reaction is through prolonged direct contact with soda lime producing low levels of fluoroform (CHF3). The amount of CHF3 obtained is similar to that produced with MAC-equivalent doses of isoflurane. No discernible degradation occurs in the presence of strong acids.
SUPRANE does not corrode stainless steel, brass, aluminum, anodized aluminum, nickel plated brass, copper, or beryllium.
Last reviewed on RxList: 4/27/2010




Suprane Drug Description
Suprane
(desflurane, USP) Volatile Liquid for Inhalation
DRUG DESCRIPTION
SUPRANE, a nonflammable liquid administered via vaporizer, is a general inhalation anesthetic. It is (±)1,2,2,2-tetrafluoroethyl difluoromethyl ether:
Some physical constants are:








Some physical constants are:



Molecular weight
168.04


Specific gravity (at 20°C/4°C)
1.465


Vapor pressure in mm Hg
669 mm Hg @ 20°C


 
731 mm Hg @ 22°C


 
757 mm Hg @


 
22.8°C (boiling point;1atm)


 
764 mm Hg @ 23°C


 
798 mm Hg @ 24°C


 
869 mm Hg @ 26°C



Partition coefficients at 37°C:



Blood/Gas
0.424


Olive Oil/Gas
18.7


Brain/Gas
0.54



Mean Component/Gas Partition Coefficients:



Polypropylene (Y piece)
6.7


Polyethylene (circuit tube)
16.2


Latex rubber (bag)
19.3


Latex rubber (bellows)
10.4


Polyvinylchloride
34.7


(endotracheal tube)
 



SUPRANE is nonflammable as defined by the requirements of International Electrotechnical
Commission 601-2-13.
SUPRANE is a colorless, volatile liquid below 22.8°C. Data indicate that SUPRANE is stable when stored under normal room lighting conditions according to instructions.
SUPRANE is chemically stable. The only known degradation reaction is through prolonged direct contact with soda lime producing low levels of fluoroform (CHF3). The amount of CHF3 obtained is similar to that produced with MAC-equivalent doses of isoflurane. No discernible degradation occurs in the presence of strong acids.
SUPRANE does not corrode stainless steel, brass, aluminum, anodized aluminum, nickel plated brass, copper, or beryllium.
Last reviewed on RxList: 4/27/2010




Suprane Drug Description
Suprane
(desflurane, USP) Volatile Liquid for Inhalation
DRUG DESCRIPTION
SUPRANE, a nonflammable liquid administered via vaporizer, is a general inhalation anesthetic. It is (±)1,2,2,2-tetrafluoroethyl difluoromethyl ether:
Some physical constants are:








Some physical constants are:



Molecular weight
168.04


Specific gravity (at 20°C/4°C)
1.465


Vapor pressure in mm Hg
669 mm Hg @ 20°C


 
731 mm Hg @ 22°C


 
757 mm Hg @


 
22.8°C (boiling point;1atm)


 
764 mm Hg @ 23°C


 
798 mm Hg @ 24°C


 
869 mm Hg @ 26°C



Partition coefficients at 37°C:



Blood/Gas
0.424


Olive Oil/Gas
18.7


Brain/Gas
0.54



Mean Component/Gas Partition Coefficients:



Polypropylene (Y piece)
6.7


Polyethylene (circuit tube)
16.2


Latex rubber (bag)
19.3


Latex rubber (bellows)
10.4


Polyvinylchloride
34.7


(endotracheal tube)
 



SUPRANE is nonflammable as defined by the requirements of International Electrotechnical
Commission 601-2-13.
SUPRANE is a colorless, volatile liquid below 22.8°C. Data indicate that SUPRANE is stable when stored under normal room lighting conditions according to instructions.
SUPRANE is chemically stable. The only known degradation reaction is through prolonged direct contact with soda lime producing low levels of fluoroform (CHF3). The amount of CHF3 obtained is similar to that produced with MAC-equivalent doses of isoflurane. No discernible degradation occurs in the presence of strong acids.
SUPRANE does not corrode stainless steel, brass, aluminum, anodized aluminum, nickel plated brass, copper, or beryllium.
Last reviewed on RxList: 4/27/2010




Suprane Drug Description
Suprane
(desflurane, USP) Volatile Liquid for Inhalation
DRUG DESCRIPTION
SUPRANE, a nonflammable liquid administered via vaporizer, is a general inhalation anesthetic. It is (±)1,2,2,2-tetrafluoroethyl difluoromethyl ether:
Some physical constants are:








Some physical constants are:



Molecular weight
168.04


Specific gravity (at 20°C/4°C)
1.465


Vapor pressure in mm Hg
669 mm Hg @ 20°C


 
731 mm Hg @ 22°C


 
757 mm Hg @


 
22.8°C (boiling point;1atm)


 
764 mm Hg @ 23°C


 
798 mm Hg @ 24°C


 
869 mm Hg @ 26°C



Partition coefficients at 37°C:



Blood/Gas
0.424


Olive Oil/Gas
18.7


Brain/Gas
0.54



Mean Component/Gas Partition Coefficients:



Polypropylene (Y piece)
6.7


Polyethylene (circuit tube)
16.2


Latex rubber (bag)
19.3


Latex rubber (bellows)
10.4


Polyvinylchloride
34.7


(endotracheal tube)
 



SUPRANE is nonflammable as defined by the requirements of International Electrotechnical
Commission 601-2-13.
SUPRANE is a colorless, volatile liquid below 22.8°C. Data indicate that SUPRANE is stable when stored under normal room lighting conditions according to instructions.
SUPRANE is chemically stable. The only known degradation reaction is through prolonged direct contact with soda lime producing low levels of fluoroform (CHF3). The amount of CHF3 obtained is similar to that produced with MAC-equivalent doses of isoflurane. No discernible degradation occurs in the presence of strong acids.
SUPRANE does not corrode stainless steel, brass, aluminum, anodized aluminum, nickel plated brass, copper, or beryllium.
Last reviewed on RxList: 4/27/2010





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Other reviews about Desflurane on web:

Desflurane (2,2,2-trifluoro-1-fluoroethyl-difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Desflurane - Wikipedia, the free encyclopedia


Learn about the prescription medication Suprane (Desflurane), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Suprane (Desflurane) Drug Information: Uses, Side Effects, Drug ...


desflurane A gaseous anesthetic agent similar to isoflurane. ... Desflurane (2,2,2-trifluoro-1-fluoroethyl-difluoromethyl ether) is a highly fluorinated methyl ethyl ether used ... Desflurane: Definition from Answers.com


Desflurane. A review of its pharmacodynamic and pharmacokinetic properties and its efficacy in general anaesthesia by Patel SS, Goa KL. Adis International Limited, Desflurane ( Suprane )


Suprane® (desflurane, USP) is indicated as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults. Suprane


desflurane Inhalation, oral/nebulization (desflurane) patient information. Detailed drug information for the consumer, includes dosage, desflurane Inhalation, oral/nebulization ... desflurane Inhalation, oral/nebulization consumer information from ...


After desflurane, it is the volatile anesthetic with the fastest onset and offset. Though desflurane has the lowest blood/gas coefficient of the currently used volatile anesthetics ... Sevoflurane - Wikipedia, the free encyclopedia


Desflurane Drug Information from Drugs.com. Includes Desflurane side effects, interactions and indications. Desflurane Drug Information, Professional


Mayo Clinic offers award-winning medical and health information and tools for healthy living. Desflurane (Inhalation Route) - MayoClinic.com


Desflurane (2,2,2-trifluoro-1-fluoroethyl-difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Together with sevoflurane, it ... Desflurane





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