Reviews Coumadin


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Coumadin Drug Description
COUMADIN® TABLETS
(warfarin sodium) Tablets, USP Crystalline
COUMADIN® FOR INJECTION
(warfarin sodium) for Injection, USP
Anticoagulant

WARNING
BLEEDING RISK
Warfarin sodium can cause major or fatal bleeding. Bleeding is more likely
to occur during the starting period and with a higher dose (resulting in a
higher INR). Risk factors for bleeding include high intensity of anticoagulation
(INR > 4.0), age ≥ 65, highly variable INRs, history of gastrointestinal
bleeding, hypertension, cerebrovascular disease, serious heart disease, anemia,
malignancy, trauma, renal insufficiency, concomitant drugs (see PRECAUTIONS),
and long duration of warfarin therapy. Regular monitoring of INR should be
performed on all treated patients. Those at high risk of bleeding may benefit
from more frequent INR monitoring, careful dose adjustment to desired INR,
and a shorter duration of therapy. Patients should be instructed about prevention
measures to minimize risk of bleeding and to report immediately to physicians
signs and symptoms of bleeding (see PATIENT INFORMATION).

DRUG DESCRIPTION



What are the possible side effects of warfarin (Coumadin, Jantoven)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

skin changes or discoloration anywhere on your body;
purple toes or fingers;
pain in your stomach, back, or sides;
low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
diarrhea,...
Read All Potential Side Effects for Coumadin »




COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting
vitamin K-dependent coagulation factors. Chemically, it is 3-(α-acetonylbenzyl)-4-hydroxycoumarin
and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium
is an isopropanol clathrate. The crystallization of warfarin sodium virtually
eliminates trace impurities present in amorphous warfarin. Its empirical formula
is C19H15NaO4, and its structural formula may be represented by the following:








Crystalline warfarin sodium occurs as a white, odorless, crystalline powder,
is discolored by light and is very soluble in water; freely soluble in alcohol;
very slightly soluble in chloroform and in ether.
COUMADIN Tablets for oral use also contain:



All strengths:
Lactose, starch and magnesium stearate


1 mg:
D&C Red No. 6 Barium Lake


2 mg:
FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


2-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


3 mg:
FD&C Yellow No. 6 Aluminum Lake,


FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


4 mg:
FD&C Blue No. 1 Aluminum Lake


5 mg:
FD&C Yellow No. 6 Aluminum Lake


6 mg:
FD&C Yellow No. 6 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


7-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Yellow No. 6 Aluminum Lake


10 mg:
Dye Free



COUMADIN for Injection is supplied as a sterile, lyophilized powder, which,
after reconstitution with 2.7 mL sterile Water for Injection, contains:




Warfarin Sodium
2 mg/mL


Sodium Phosphate, Dibasic, Heptahydrate
4.98 mg/mL


Sodium Phosphate, Monobasic, Monohydrate
0.194 mg/mL


Sodium Chloride
0.1 mg/mL


Mannitol
38.0 mg/mL


Sodium Hydroxide, as needed for pH adjustment to
8.1 to 8.3


Last reviewed on RxList: 2/18/2010




Coumadin Drug Description
COUMADIN® TABLETS
(warfarin sodium) Tablets, USP Crystalline
COUMADIN® FOR INJECTION
(warfarin sodium) for Injection, USP
Anticoagulant

WARNING
BLEEDING RISK
Warfarin sodium can cause major or fatal bleeding. Bleeding is more likely
to occur during the starting period and with a higher dose (resulting in a
higher INR). Risk factors for bleeding include high intensity of anticoagulation
(INR > 4.0), age ≥ 65, highly variable INRs, history of gastrointestinal
bleeding, hypertension, cerebrovascular disease, serious heart disease, anemia,
malignancy, trauma, renal insufficiency, concomitant drugs (see PRECAUTIONS),
and long duration of warfarin therapy. Regular monitoring of INR should be
performed on all treated patients. Those at high risk of bleeding may benefit
from more frequent INR monitoring, careful dose adjustment to desired INR,
and a shorter duration of therapy. Patients should be instructed about prevention
measures to minimize risk of bleeding and to report immediately to physicians
signs and symptoms of bleeding (see PATIENT INFORMATION).

DRUG DESCRIPTION



What are the possible side effects of warfarin (Coumadin, Jantoven)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

skin changes or discoloration anywhere on your body;
purple toes or fingers;
pain in your stomach, back, or sides;
low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
diarrhea,...
Read All Potential Side Effects for Coumadin »




COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting
vitamin K-dependent coagulation factors. Chemically, it is 3-(α-acetonylbenzyl)-4-hydroxycoumarin
and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium
is an isopropanol clathrate. The crystallization of warfarin sodium virtually
eliminates trace impurities present in amorphous warfarin. Its empirical formula
is C19H15NaO4, and its structural formula may be represented by the following:








Crystalline warfarin sodium occurs as a white, odorless, crystalline powder,
is discolored by light and is very soluble in water; freely soluble in alcohol;
very slightly soluble in chloroform and in ether.
COUMADIN Tablets for oral use also contain:



All strengths:
Lactose, starch and magnesium stearate


1 mg:
D&C Red No. 6 Barium Lake


2 mg:
FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


2-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


3 mg:
FD&C Yellow No. 6 Aluminum Lake,


FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


4 mg:
FD&C Blue No. 1 Aluminum Lake


5 mg:
FD&C Yellow No. 6 Aluminum Lake


6 mg:
FD&C Yellow No. 6 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


7-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Yellow No. 6 Aluminum Lake


10 mg:
Dye Free



COUMADIN for Injection is supplied as a sterile, lyophilized powder, which,
after reconstitution with 2.7 mL sterile Water for Injection, contains:




Warfarin Sodium
2 mg/mL


Sodium Phosphate, Dibasic, Heptahydrate
4.98 mg/mL


Sodium Phosphate, Monobasic, Monohydrate
0.194 mg/mL


Sodium Chloride
0.1 mg/mL


Mannitol
38.0 mg/mL


Sodium Hydroxide, as needed for pH adjustment to
8.1 to 8.3


Last reviewed on RxList: 2/18/2010




Coumadin Drug Description
COUMADIN® TABLETS
(warfarin sodium) Tablets, USP Crystalline
COUMADIN® FOR INJECTION
(warfarin sodium) for Injection, USP
Anticoagulant

WARNING
BLEEDING RISK
Warfarin sodium can cause major or fatal bleeding. Bleeding is more likely
to occur during the starting period and with a higher dose (resulting in a
higher INR). Risk factors for bleeding include high intensity of anticoagulation
(INR > 4.0), age ≥ 65, highly variable INRs, history of gastrointestinal
bleeding, hypertension, cerebrovascular disease, serious heart disease, anemia,
malignancy, trauma, renal insufficiency, concomitant drugs (see PRECAUTIONS),
and long duration of warfarin therapy. Regular monitoring of INR should be
performed on all treated patients. Those at high risk of bleeding may benefit
from more frequent INR monitoring, careful dose adjustment to desired INR,
and a shorter duration of therapy. Patients should be instructed about prevention
measures to minimize risk of bleeding and to report immediately to physicians
signs and symptoms of bleeding (see PATIENT INFORMATION).

DRUG DESCRIPTION



What are the possible side effects of warfarin (Coumadin, Jantoven)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

skin changes or discoloration anywhere on your body;
purple toes or fingers;
pain in your stomach, back, or sides;
low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
diarrhea,...
Read All Potential Side Effects for Coumadin »




COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting
vitamin K-dependent coagulation factors. Chemically, it is 3-(α-acetonylbenzyl)-4-hydroxycoumarin
and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium
is an isopropanol clathrate. The crystallization of warfarin sodium virtually
eliminates trace impurities present in amorphous warfarin. Its empirical formula
is C19H15NaO4, and its structural formula may be represented by the following:








Crystalline warfarin sodium occurs as a white, odorless, crystalline powder,
is discolored by light and is very soluble in water; freely soluble in alcohol;
very slightly soluble in chloroform and in ether.
COUMADIN Tablets for oral use also contain:



All strengths:
Lactose, starch and magnesium stearate


1 mg:
D&C Red No. 6 Barium Lake


2 mg:
FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


2-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


3 mg:
FD&C Yellow No. 6 Aluminum Lake,


FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


4 mg:
FD&C Blue No. 1 Aluminum Lake


5 mg:
FD&C Yellow No. 6 Aluminum Lake


6 mg:
FD&C Yellow No. 6 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


7-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Yellow No. 6 Aluminum Lake


10 mg:
Dye Free



COUMADIN for Injection is supplied as a sterile, lyophilized powder, which,
after reconstitution with 2.7 mL sterile Water for Injection, contains:




Warfarin Sodium
2 mg/mL


Sodium Phosphate, Dibasic, Heptahydrate
4.98 mg/mL


Sodium Phosphate, Monobasic, Monohydrate
0.194 mg/mL


Sodium Chloride
0.1 mg/mL


Mannitol
38.0 mg/mL


Sodium Hydroxide, as needed for pH adjustment to
8.1 to 8.3


Last reviewed on RxList: 2/18/2010




Coumadin Drug Description
COUMADIN® TABLETS
(warfarin sodium) Tablets, USP Crystalline
COUMADIN® FOR INJECTION
(warfarin sodium) for Injection, USP
Anticoagulant

WARNING
BLEEDING RISK
Warfarin sodium can cause major or fatal bleeding. Bleeding is more likely
to occur during the starting period and with a higher dose (resulting in a
higher INR). Risk factors for bleeding include high intensity of anticoagulation
(INR > 4.0), age ≥ 65, highly variable INRs, history of gastrointestinal
bleeding, hypertension, cerebrovascular disease, serious heart disease, anemia,
malignancy, trauma, renal insufficiency, concomitant drugs (see PRECAUTIONS),
and long duration of warfarin therapy. Regular monitoring of INR should be
performed on all treated patients. Those at high risk of bleeding may benefit
from more frequent INR monitoring, careful dose adjustment to desired INR,
and a shorter duration of therapy. Patients should be instructed about prevention
measures to minimize risk of bleeding and to report immediately to physicians
signs and symptoms of bleeding (see PATIENT INFORMATION).

DRUG DESCRIPTION



What are the possible side effects of warfarin (Coumadin, Jantoven)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

skin changes or discoloration anywhere on your body;
purple toes or fingers;
pain in your stomach, back, or sides;
low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
diarrhea,...
Read All Potential Side Effects for Coumadin »




COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting
vitamin K-dependent coagulation factors. Chemically, it is 3-(α-acetonylbenzyl)-4-hydroxycoumarin
and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium
is an isopropanol clathrate. The crystallization of warfarin sodium virtually
eliminates trace impurities present in amorphous warfarin. Its empirical formula
is C19H15NaO4, and its structural formula may be represented by the following:








Crystalline warfarin sodium occurs as a white, odorless, crystalline powder,
is discolored by light and is very soluble in water; freely soluble in alcohol;
very slightly soluble in chloroform and in ether.
COUMADIN Tablets for oral use also contain:



All strengths:
Lactose, starch and magnesium stearate


1 mg:
D&C Red No. 6 Barium Lake


2 mg:
FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


2-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


3 mg:
FD&C Yellow No. 6 Aluminum Lake,


FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


4 mg:
FD&C Blue No. 1 Aluminum Lake


5 mg:
FD&C Yellow No. 6 Aluminum Lake


6 mg:
FD&C Yellow No. 6 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


7-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Yellow No. 6 Aluminum Lake


10 mg:
Dye Free



COUMADIN for Injection is supplied as a sterile, lyophilized powder, which,
after reconstitution with 2.7 mL sterile Water for Injection, contains:




Warfarin Sodium
2 mg/mL


Sodium Phosphate, Dibasic, Heptahydrate
4.98 mg/mL


Sodium Phosphate, Monobasic, Monohydrate
0.194 mg/mL


Sodium Chloride
0.1 mg/mL


Mannitol
38.0 mg/mL


Sodium Hydroxide, as needed for pH adjustment to
8.1 to 8.3


Last reviewed on RxList: 2/18/2010




Coumadin Drug Description
COUMADIN® TABLETS
(warfarin sodium) Tablets, USP Crystalline
COUMADIN® FOR INJECTION
(warfarin sodium) for Injection, USP
Anticoagulant

WARNING
BLEEDING RISK
Warfarin sodium can cause major or fatal bleeding. Bleeding is more likely
to occur during the starting period and with a higher dose (resulting in a
higher INR). Risk factors for bleeding include high intensity of anticoagulation
(INR > 4.0), age ≥ 65, highly variable INRs, history of gastrointestinal
bleeding, hypertension, cerebrovascular disease, serious heart disease, anemia,
malignancy, trauma, renal insufficiency, concomitant drugs (see PRECAUTIONS),
and long duration of warfarin therapy. Regular monitoring of INR should be
performed on all treated patients. Those at high risk of bleeding may benefit
from more frequent INR monitoring, careful dose adjustment to desired INR,
and a shorter duration of therapy. Patients should be instructed about prevention
measures to minimize risk of bleeding and to report immediately to physicians
signs and symptoms of bleeding (see PATIENT INFORMATION).

DRUG DESCRIPTION



What are the possible side effects of warfarin (Coumadin, Jantoven)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

skin changes or discoloration anywhere on your body;
purple toes or fingers;
pain in your stomach, back, or sides;
low fever, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
diarrhea,...
Read All Potential Side Effects for Coumadin »




COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting
vitamin K-dependent coagulation factors. Chemically, it is 3-(α-acetonylbenzyl)-4-hydroxycoumarin
and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium
is an isopropanol clathrate. The crystallization of warfarin sodium virtually
eliminates trace impurities present in amorphous warfarin. Its empirical formula
is C19H15NaO4, and its structural formula may be represented by the following:








Crystalline warfarin sodium occurs as a white, odorless, crystalline powder,
is discolored by light and is very soluble in water; freely soluble in alcohol;
very slightly soluble in chloroform and in ether.
COUMADIN Tablets for oral use also contain:



All strengths:
Lactose, starch and magnesium stearate


1 mg:
D&C Red No. 6 Barium Lake


2 mg:
FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


2-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


3 mg:
FD&C Yellow No. 6 Aluminum Lake,


FD&C Blue No. 2 Aluminum Lake and


FD&C Red No. 40 Aluminum Lake


4 mg:
FD&C Blue No. 1 Aluminum Lake


5 mg:
FD&C Yellow No. 6 Aluminum Lake


6 mg:
FD&C Yellow No. 6 Aluminum Lake and


FD&C Blue No. 1 Aluminum Lake


7-½ mg:
D&C Yellow No. 10 Aluminum Lake and


FD&C Yellow No. 6 Aluminum Lake


10 mg:
Dye Free



COUMADIN for Injection is supplied as a sterile, lyophilized powder, which,
after reconstitution with 2.7 mL sterile Water for Injection, contains:




Warfarin Sodium
2 mg/mL


Sodium Phosphate, Dibasic, Heptahydrate
4.98 mg/mL


Sodium Phosphate, Monobasic, Monohydrate
0.194 mg/mL


Sodium Chloride
0.1 mg/mL


Mannitol
38.0 mg/mL


Sodium Hydroxide, as needed for pH adjustment to
8.1 to 8.3


Last reviewed on RxList: 2/18/2010





Other reviews about Coumadin on wordpress

Coumadin Clinic
  by Danny Lee
For those of you who had been coming to the Coumadin clinic here at Odenton, may have noticed a string of appointment cancellations. This is because one of […]


The Coumadin (warfarin) Diet.
  by Danny Lee
For people on the blood thinner Coumadin (generic: warfarin) it can be confusing to know what foods will affect your levels. First, we should cover what is Coumadin […]


Can I get a dental implant if I take Coumadin?
  by robertgougaloff
Coumadin is an anticoagulant (blood thinner), which reduces the formation of blood clots. It does so by blocking the synthesis of certain clotting factors. A reduction […]


Coumadin and fish oil
  by pets5care
Coumadin (Warfarin) treats or prevents blood clots that may occur in the veins and lungs. If the drug use. Prevents Coumadin processing or lungs, veins in clotting occur. In addition […]


Coumadin Clinic
  by RB
After a quiet weekend on bedrest, monday brought some excitement.  I had an appointment in the late afternoon with the hematologist, so I knew at some point I would […]


PT/INR Levels
  by RB
While taking the blood thinning drug Coumadin, my blood levels (also known as my PT/INR) must be monitored to make sure that my blood does not get too […]


Coumadin and Tooth Extractions
  by Robert Lemmon
On several occasions dentists have asked that I stop patient's Coumadin prior to dental extractions.  I have always complied with this request.  However, a cardiologist told one of […]


FDA MedWatch - Coumadin 1 mg Tablet Blister Packs: Recall
  by irbtipoftheweek
ISSUE: Bristol-Myers Squibb determined that some of the tablets, over time, may not meet specification for isopropanol. Isopropanol is used to maintain the active ingredient, Coumadin, in the […]


New Alternative to Coumadin and Warfarin?
  by keepyourhearthealthy
[caption id="attachment_588" align="alignright" width="150" caption="photo by Michal Marcol"][/caption] Patients with atrial fibrillation know all too well the problems with Coumadin and warfarin. Atrial fibrillation is a very common arrhythmia […]


Goodbye Coumadin!! Hopefully Soon...
  by keepyourhearthealthy
[caption id="attachment_671" align="alignleft" width="99" caption="photo by graur razvan ionut"][/caption] Praise God!  The FDA has unanimously approved an alternative to Coumadin (warfarin) in atrial fibrillation.  The new drug called Pradaxa […]



Other reviews about Coumadin on web:

Product information, patient education, clinical data, helpful links and services are available for patients and healthcare professionals for warfarin sodium. Welcome to Coumadin.com


Coumadin (warfarin) is used to prevent heart attacks, strokes, and blood clots in veins and arteries. Includes Coumadin side effects, interactions and indications. Coumadin Information from Drugs.com


Warfarin (also known under the brand names Coumadin, Jantoven, Marevan, Lawarin, and Waran) is an anticoagulant. It was initially marketed as a pesticide against rats and mice ... Warfarin - Wikipedia, the free encyclopedia


Learn about the prescription medication Coumadin (Warfarin Sodium), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Coumadin (Warfarin Sodium) Drug Information: Uses, Side Effects ...


Coumadin information from Drugs.com. Coumadin is an anticoagulant (blood thinner). It is prescribed to: Prevent and/or treat a blood clot that has formed within a blood vessel or ... Coumadin patient advice including side effects


Welcome to Coumadin.com | For Patients & Caregivers ... Warfarin Sodium) Crystalline Has Been Helping to Protect Appropriate Patients for Over 50 Years. Welcome to Coumadin.com | For Patients & Caregivers


Coumadin® acts by impairing the utilization of Vitamin K. The liver requires Vitamin K for the manufacturing of certain key proteins in the native clotting mechanism. SAMMC Departments: Coumadin - Dietary Considerations


Guide for heart patients on what to expect and what to watch out for during Coumadin(R)/warfarin therapy. Your Guide to Coumadin®/Warfarin Therapy


Coumadin is an anticoagulant drug often prescribed to treat or prevent blood clots. This article on the eMedTV site describes the effects of this medication, explains how it ... Coumadin


Coumadin® is a safe drug when administered and monitored properly. Indeed, oral anticoagulation is a vital treatment for certain conditions, such as those listed on the ... SAMMC Departments: Coumadin - Pregnancy





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