Reviews Combivir


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Combivir Drug Description
COMBIVIR®
(lamivudine and zidovudine) Tablets 150 mg/300 mg

WARNING: HEMATOLOGIC TOXICITY, MYOPATHY, LACTIC ACIDOSIS, EXACERBATIONS
OF HEPATITIS B
Zidovudine, one of the 2 active ingredients in COMBIVIR, has been associated
with hematologic toxicity including neutropenia and anemia, particularly in
patients with advanced HIV-1 disease [see WARNINGS AND PRECAUTIONS].
Prolonged use of zidovudine has been associated with symptomatic myopathy
[see WARNINGS AND PRECAUTIONS].
Lactic acidosis and hepatomegaly with steatosis, including fatal cases,
have been reported with the use of nucleoside analogues alone or in combination,
including lamivudine, zidovudine, and other antiretrovirals. Suspend treatment
if clinical or laboratory findings suggestive of lactic acidosis or pronounced
hepatotoxicity occur [see WARNINGS AND PRECAUTIONS].
Acute exacerbations of hepatitis B have been reported in patients who are
co-infected with hepatitis B virus (HBV) and HIV-1 and have discontinued lamivudine,
which is one component of COMBIVIR. Hepatic function should be monitored closely
with both clinical and laboratory follow-up for at least several months in
patients who discontinue COMBIVIR and are co-infected with HIV-1 and HBV.
If appropriate, initiation of anti-hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of lamivudine and zidovudine (Combivir)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

muscle pain or weakness;
numb or cold feeling in your arms and...
Read All Potential Side Effects for Combivir »




COMBIVIR: COMBIVIR Tablets are combination tablets containing lamivudine
and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine,
AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1.
COMBIVIR Tablets are for oral administration. Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine, and the inactive ingredients colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide.
Lamivudine: The chemical name of lamivudine is (2R,cis)-4-amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one.
Lamivudine is the (-)enantiomer of a dideoxy analogue of cytidine. Lamivudine
has also been referred to as (-)2',3'-dideoxy, 3'-thiacytidine. It has a molecular
formula of C8H11N3O3S and a molecular
weight of 229.3. It has the following structural formula:








Lamivudine is a white to off-white crystalline solid with a solubility of approximately 70 mg/mL in water at 20°C.
Zidovudine: The chemical name of zidovudine is 3'-azido-3'-deoxythymidine.
It has a molecular formula of C10H13N5O4
and a molecular weight of 267.24. It has the following structural formula:








Zidovudine is a white to beige, odorless, crystalline solid with a solubility of 20.1 mg/mL in water at 25°C.Last reviewed on RxList: 3/11/2009




Combivir Drug Description
COMBIVIR®
(lamivudine and zidovudine) Tablets 150 mg/300 mg

WARNING: HEMATOLOGIC TOXICITY, MYOPATHY, LACTIC ACIDOSIS, EXACERBATIONS
OF HEPATITIS B
Zidovudine, one of the 2 active ingredients in COMBIVIR, has been associated
with hematologic toxicity including neutropenia and anemia, particularly in
patients with advanced HIV-1 disease [see WARNINGS AND PRECAUTIONS].
Prolonged use of zidovudine has been associated with symptomatic myopathy
[see WARNINGS AND PRECAUTIONS].
Lactic acidosis and hepatomegaly with steatosis, including fatal cases,
have been reported with the use of nucleoside analogues alone or in combination,
including lamivudine, zidovudine, and other antiretrovirals. Suspend treatment
if clinical or laboratory findings suggestive of lactic acidosis or pronounced
hepatotoxicity occur [see WARNINGS AND PRECAUTIONS].
Acute exacerbations of hepatitis B have been reported in patients who are
co-infected with hepatitis B virus (HBV) and HIV-1 and have discontinued lamivudine,
which is one component of COMBIVIR. Hepatic function should be monitored closely
with both clinical and laboratory follow-up for at least several months in
patients who discontinue COMBIVIR and are co-infected with HIV-1 and HBV.
If appropriate, initiation of anti-hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of lamivudine and zidovudine (Combivir)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

muscle pain or weakness;
numb or cold feeling in your arms and...
Read All Potential Side Effects for Combivir »




COMBIVIR: COMBIVIR Tablets are combination tablets containing lamivudine
and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine,
AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1.
COMBIVIR Tablets are for oral administration. Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine, and the inactive ingredients colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide.
Lamivudine: The chemical name of lamivudine is (2R,cis)-4-amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one.
Lamivudine is the (-)enantiomer of a dideoxy analogue of cytidine. Lamivudine
has also been referred to as (-)2',3'-dideoxy, 3'-thiacytidine. It has a molecular
formula of C8H11N3O3S and a molecular
weight of 229.3. It has the following structural formula:








Lamivudine is a white to off-white crystalline solid with a solubility of approximately 70 mg/mL in water at 20°C.
Zidovudine: The chemical name of zidovudine is 3'-azido-3'-deoxythymidine.
It has a molecular formula of C10H13N5O4
and a molecular weight of 267.24. It has the following structural formula:








Zidovudine is a white to beige, odorless, crystalline solid with a solubility of 20.1 mg/mL in water at 25°C.Last reviewed on RxList: 3/11/2009




Combivir Drug Description
COMBIVIR®
(lamivudine and zidovudine) Tablets 150 mg/300 mg

WARNING: HEMATOLOGIC TOXICITY, MYOPATHY, LACTIC ACIDOSIS, EXACERBATIONS
OF HEPATITIS B
Zidovudine, one of the 2 active ingredients in COMBIVIR, has been associated
with hematologic toxicity including neutropenia and anemia, particularly in
patients with advanced HIV-1 disease [see WARNINGS AND PRECAUTIONS].
Prolonged use of zidovudine has been associated with symptomatic myopathy
[see WARNINGS AND PRECAUTIONS].
Lactic acidosis and hepatomegaly with steatosis, including fatal cases,
have been reported with the use of nucleoside analogues alone or in combination,
including lamivudine, zidovudine, and other antiretrovirals. Suspend treatment
if clinical or laboratory findings suggestive of lactic acidosis or pronounced
hepatotoxicity occur [see WARNINGS AND PRECAUTIONS].
Acute exacerbations of hepatitis B have been reported in patients who are
co-infected with hepatitis B virus (HBV) and HIV-1 and have discontinued lamivudine,
which is one component of COMBIVIR. Hepatic function should be monitored closely
with both clinical and laboratory follow-up for at least several months in
patients who discontinue COMBIVIR and are co-infected with HIV-1 and HBV.
If appropriate, initiation of anti-hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of lamivudine and zidovudine (Combivir)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

muscle pain or weakness;
numb or cold feeling in your arms and...
Read All Potential Side Effects for Combivir »




COMBIVIR: COMBIVIR Tablets are combination tablets containing lamivudine
and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine,
AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1.
COMBIVIR Tablets are for oral administration. Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine, and the inactive ingredients colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide.
Lamivudine: The chemical name of lamivudine is (2R,cis)-4-amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one.
Lamivudine is the (-)enantiomer of a dideoxy analogue of cytidine. Lamivudine
has also been referred to as (-)2',3'-dideoxy, 3'-thiacytidine. It has a molecular
formula of C8H11N3O3S and a molecular
weight of 229.3. It has the following structural formula:








Lamivudine is a white to off-white crystalline solid with a solubility of approximately 70 mg/mL in water at 20°C.
Zidovudine: The chemical name of zidovudine is 3'-azido-3'-deoxythymidine.
It has a molecular formula of C10H13N5O4
and a molecular weight of 267.24. It has the following structural formula:








Zidovudine is a white to beige, odorless, crystalline solid with a solubility of 20.1 mg/mL in water at 25°C.Last reviewed on RxList: 3/11/2009




Combivir Drug Description
COMBIVIR®
(lamivudine and zidovudine) Tablets 150 mg/300 mg

WARNING: HEMATOLOGIC TOXICITY, MYOPATHY, LACTIC ACIDOSIS, EXACERBATIONS
OF HEPATITIS B
Zidovudine, one of the 2 active ingredients in COMBIVIR, has been associated
with hematologic toxicity including neutropenia and anemia, particularly in
patients with advanced HIV-1 disease [see WARNINGS AND PRECAUTIONS].
Prolonged use of zidovudine has been associated with symptomatic myopathy
[see WARNINGS AND PRECAUTIONS].
Lactic acidosis and hepatomegaly with steatosis, including fatal cases,
have been reported with the use of nucleoside analogues alone or in combination,
including lamivudine, zidovudine, and other antiretrovirals. Suspend treatment
if clinical or laboratory findings suggestive of lactic acidosis or pronounced
hepatotoxicity occur [see WARNINGS AND PRECAUTIONS].
Acute exacerbations of hepatitis B have been reported in patients who are
co-infected with hepatitis B virus (HBV) and HIV-1 and have discontinued lamivudine,
which is one component of COMBIVIR. Hepatic function should be monitored closely
with both clinical and laboratory follow-up for at least several months in
patients who discontinue COMBIVIR and are co-infected with HIV-1 and HBV.
If appropriate, initiation of anti-hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of lamivudine and zidovudine (Combivir)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

muscle pain or weakness;
numb or cold feeling in your arms and...
Read All Potential Side Effects for Combivir »




COMBIVIR: COMBIVIR Tablets are combination tablets containing lamivudine
and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine,
AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1.
COMBIVIR Tablets are for oral administration. Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine, and the inactive ingredients colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide.
Lamivudine: The chemical name of lamivudine is (2R,cis)-4-amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one.
Lamivudine is the (-)enantiomer of a dideoxy analogue of cytidine. Lamivudine
has also been referred to as (-)2',3'-dideoxy, 3'-thiacytidine. It has a molecular
formula of C8H11N3O3S and a molecular
weight of 229.3. It has the following structural formula:








Lamivudine is a white to off-white crystalline solid with a solubility of approximately 70 mg/mL in water at 20°C.
Zidovudine: The chemical name of zidovudine is 3'-azido-3'-deoxythymidine.
It has a molecular formula of C10H13N5O4
and a molecular weight of 267.24. It has the following structural formula:








Zidovudine is a white to beige, odorless, crystalline solid with a solubility of 20.1 mg/mL in water at 25°C.Last reviewed on RxList: 3/11/2009




Combivir Drug Description
COMBIVIR®
(lamivudine and zidovudine) Tablets 150 mg/300 mg

WARNING: HEMATOLOGIC TOXICITY, MYOPATHY, LACTIC ACIDOSIS, EXACERBATIONS
OF HEPATITIS B
Zidovudine, one of the 2 active ingredients in COMBIVIR, has been associated
with hematologic toxicity including neutropenia and anemia, particularly in
patients with advanced HIV-1 disease [see WARNINGS AND PRECAUTIONS].
Prolonged use of zidovudine has been associated with symptomatic myopathy
[see WARNINGS AND PRECAUTIONS].
Lactic acidosis and hepatomegaly with steatosis, including fatal cases,
have been reported with the use of nucleoside analogues alone or in combination,
including lamivudine, zidovudine, and other antiretrovirals. Suspend treatment
if clinical or laboratory findings suggestive of lactic acidosis or pronounced
hepatotoxicity occur [see WARNINGS AND PRECAUTIONS].
Acute exacerbations of hepatitis B have been reported in patients who are
co-infected with hepatitis B virus (HBV) and HIV-1 and have discontinued lamivudine,
which is one component of COMBIVIR. Hepatic function should be monitored closely
with both clinical and laboratory follow-up for at least several months in
patients who discontinue COMBIVIR and are co-infected with HIV-1 and HBV.
If appropriate, initiation of anti-hepatitis B therapy may be warranted [see
WARNINGS AND PRECAUTIONS].

DRUG DESCRIPTION



What are the possible side effects of lamivudine and zidovudine (Combivir)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:

muscle pain or weakness;
numb or cold feeling in your arms and...
Read All Potential Side Effects for Combivir »




COMBIVIR: COMBIVIR Tablets are combination tablets containing lamivudine
and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine,
AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1.
COMBIVIR Tablets are for oral administration. Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine, and the inactive ingredients colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide.
Lamivudine: The chemical name of lamivudine is (2R,cis)-4-amino-l-(2-hydroxymethyl-l,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one.
Lamivudine is the (-)enantiomer of a dideoxy analogue of cytidine. Lamivudine
has also been referred to as (-)2',3'-dideoxy, 3'-thiacytidine. It has a molecular
formula of C8H11N3O3S and a molecular
weight of 229.3. It has the following structural formula:








Lamivudine is a white to off-white crystalline solid with a solubility of approximately 70 mg/mL in water at 20°C.
Zidovudine: The chemical name of zidovudine is 3'-azido-3'-deoxythymidine.
It has a molecular formula of C10H13N5O4
and a molecular weight of 267.24. It has the following structural formula:








Zidovudine is a white to beige, odorless, crystalline solid with a solubility of 20.1 mg/mL in water at 25°C.Last reviewed on RxList: 3/11/2009





Other reviews about Combivir on wordpress

Buy Combivir Online Order Cheap Combivir Generic Purchase Discount Without Prescription
  by worlddnews
FOLLOW THIS LINK FOR ENTER TO TRUSTED & REPUTABLE ONLINE DRUGSTORE WHERE YOU CAN GET ALL QUALIFIED INFORMATION ABOUT Combivir ONLINE     Still you can try it. Some researchers believe […]


Glaxo's patent on AIDS drug opposed by INP+ in India
  by mais
Glaxo's patent on AIDS drug opposed by INP+ in India The World Trade Review: "Intellectual Property Rights (TRIPs), 16-30 April 2006 Mumbai: People living with HIV/AIDS are taking on drug […]


Treatment News : Fewer Side Effects with Videx/Epivir vs. Combivir
  by pozlife
  Fewer Side Effects with Videx/Epivir vs. Combivir(AIDSmeds.com) by Tim Horn A team of Spanish researchers is finding that, when combined with Sustiva® (efavirenz), Videx® EC (didanosine […]


Treatment News : AIDS Drugs Sales to Top $10 Billion by 2015 - by Ben Hirschler
  by pozlife
  The launch of new drugs and an increase in the number of people diagnosed with HIV is set to make AIDS medicine a $10.6 billion market […]


ARTICLE: Costs of Common HIV Meds
  by ucanwalkonwater
  It's no secret, HIV medicines are very expensive. For most, insurances, drug assistance programs, or community resources pay most of the cost. But what about those who are […]


Pfizer and GSK form HIV joing venture
  by silico
The Guardian reports that GSK and Pfizer today announced that they intend to create a new company, headquartered in London but as yet unnamed, to manage their HIV […]


Partnering Profiles: GlaxoSmithKline
  by silico
How many partners does GSK have? Like many other pharmaceutical companies GSK does not reveal its exact number of partners. The company’s website, however, indicates GSK has hundreds of […]


Ft. Hood Jihadi: Inside his house...
  by Kyros
From the Dallas Morning News:<--- A label from the packaging for a LASER SIGHT.Off to find out more details. In the meantime, check out the rest […]


Fort Hood Terrorist: Hasan Worried About HIV
  by hgguy
ABC News Chief Investigative Reporter Brian Ross at his  blog The Blotter says Fort Hood terrorist Major Nidal Hasan  worries about  HIV blood test taken a week  prior […]


Drug free
  by mansfield4
I have been taking a combination of medications for the last 30 days. Combivir and Efavirenz to prevent any possible HIV I picked up when injured in Haiti, […]



Other reviews about Combivir on web:

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use COMBIVIR safely and effectively. See full prescribing information for ... US Product Labeling @std Template for PLR


Combivir (lamivudine and zidovudine) is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Includes Combivir side effects, interactions and indications. Combivir Information from Drugs.com


Combivir is the brand name for a pharmaceutical treatment for HIV infection. It is a fixed dose combination of two antiretroviral drugs, lamivudine (also called 3TC, with the brand ... Combivir - Wikipedia, the free encyclopedia


Learn about the prescription medication Combivir (Lamivudine, Zidovudine), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Combivir (Lamivudine, Zidovudine) Drug Information: Uses, Side ...


All about Combivir. View complete and up to date Combivir information - part of the Drugs.com trusted medication database. Combivir Facts and Comparisons at Drugs.com


Buy Combivir online for lowest prices without a prescription. Any type of credit card or debit card can be used to order Combivir. Cheapest Combivir online. Buy Combivir now!


Combivir, a prescription medication, helps prevent the HIV virus from spreading to uninfected cells. This eMedTV resource describes the drug in detail, explaining how it works ... Combivir


Up-to-date HIV and AIDS and Hepatitis treatment and care information Combivir


The information on this page is seed content provided by an organization. Please help improve this Article by adding to it. If you are a physician or PhD, learn how to edit. If ... Clinical:Combivir (lamivudine and zidovudine) - Medpedia


Complete info about Combivir (AZT 3TC), a nucleoside analogue AIDSmeds.com - Combivir





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