Reviews Colesevelam Hcl


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Welchol Drug Description
WELCHOL
(colesevelam hydrochloride)
DRUG DESCRIPTION



What are the possible side effects of colesevelam (Welchol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using colesevelam and call your doctor at once if you have severe constipation or stomach pain.
Less serious side effects may include:

constipation;
nausea, upset stomach pain, gas, indigestion;
feeling weak or tired;
muscle weakness; or
runny nose, sore...
Read All Potential Side Effects for Welchol »




WELCHOL (colesevelam hydrochloride) is a non-absorbed,
polymeric, lipid-lowering and glucose-lowering agent intended for oral
administration. Colesevelam hydrochloride is a high-capacity bile acid-binding
molecule.
Colesevelam hydrochloride is poly(allylamine hydrochloride)
cross-linked with epichlorohydrin and alkylated with 1-bromodecane and
(6-bromohexyl)-trimethylammonium bromide. The chemical name (IUPAC) of
colesevelam hydrochloride is allylamine polymer with 1-chloro-2,3-epoxypropane,
[6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine,
hydrochloride. The chemical structure of colesevelam hydrochloride is
represented by the following formula:








wherein (a) represents allyl amine monomer units that have
not been alkylated by either of the 1-bromodecane or
(6-bromohexyl)-trimethylammonium bromide alkylating agents or cross-linked by
epichlorohydrin; (b) represents allyl amine units that have undergone
crosslinking with epichlorohydrin; (c) represents allyl amine units that have
been alkylated with a decyl group; (d) represents allyl amine units that have
been alkylated with a (6-trimethylammonium) hexyl group, and m represents a
number ≥ 100 to indicate an extended polymer network. A small amount of
the amines are dialkylated, and are not depicted in the formula above. No
regular order of the groups is implied by the structure; cross-linking and
alkylation are expected to occur randomly along the polymer chains. A large
amount of the amines are protonated. The polymer is depicted in the
hydrochloride form; a small amount of the halides are bromide. Colesevelam
hydrochloride is hydrophilic and insoluble in water.
WELCHOL Tablets are an off-white, oval, film-coated, solid
tablet containing 625 mg colesevelam hydrochloride. In addition, each tablet
contains the following inactive ingredients: magnesium stearate,
microcrystalline cellulose, silicon dioxide, HPMC (hydroxypropyl
methylcellulose), and acetylated monoglyceride. The tablets are imprinted using
a water-soluble black ink.
WELCHOL for Oral Suspension is a citrus-flavored, white to
pale yellow powder containing yellow granules packaged in single-dose packets
containing either 1.875 gram or 3.75 gram colesevelam hydrochloride. In
addition, each packet contains the following inactive ingredients: lemon
flavor, orange flavor, propylene glycol alginate, simethicone, aspartame,
citric acid, medium chain triglycerides, and magnesium trisilicate.
PHENYLKETONURICS: WELCHOL for Oral Suspension
contains 24 mg phenylalanine per 1.875 gram dose and 48 mg phenylalanine per
3.75 gram dose.Last reviewed on RxList: 10/27/2009




Welchol Drug Description
WELCHOL
(colesevelam hydrochloride)
DRUG DESCRIPTION



What are the possible side effects of colesevelam (Welchol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using colesevelam and call your doctor at once if you have severe constipation or stomach pain.
Less serious side effects may include:

constipation;
nausea, upset stomach pain, gas, indigestion;
feeling weak or tired;
muscle weakness; or
runny nose, sore...
Read All Potential Side Effects for Welchol »




WELCHOL (colesevelam hydrochloride) is a non-absorbed,
polymeric, lipid-lowering and glucose-lowering agent intended for oral
administration. Colesevelam hydrochloride is a high-capacity bile acid-binding
molecule.
Colesevelam hydrochloride is poly(allylamine hydrochloride)
cross-linked with epichlorohydrin and alkylated with 1-bromodecane and
(6-bromohexyl)-trimethylammonium bromide. The chemical name (IUPAC) of
colesevelam hydrochloride is allylamine polymer with 1-chloro-2,3-epoxypropane,
[6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine,
hydrochloride. The chemical structure of colesevelam hydrochloride is
represented by the following formula:








wherein (a) represents allyl amine monomer units that have
not been alkylated by either of the 1-bromodecane or
(6-bromohexyl)-trimethylammonium bromide alkylating agents or cross-linked by
epichlorohydrin; (b) represents allyl amine units that have undergone
crosslinking with epichlorohydrin; (c) represents allyl amine units that have
been alkylated with a decyl group; (d) represents allyl amine units that have
been alkylated with a (6-trimethylammonium) hexyl group, and m represents a
number ≥ 100 to indicate an extended polymer network. A small amount of
the amines are dialkylated, and are not depicted in the formula above. No
regular order of the groups is implied by the structure; cross-linking and
alkylation are expected to occur randomly along the polymer chains. A large
amount of the amines are protonated. The polymer is depicted in the
hydrochloride form; a small amount of the halides are bromide. Colesevelam
hydrochloride is hydrophilic and insoluble in water.
WELCHOL Tablets are an off-white, oval, film-coated, solid
tablet containing 625 mg colesevelam hydrochloride. In addition, each tablet
contains the following inactive ingredients: magnesium stearate,
microcrystalline cellulose, silicon dioxide, HPMC (hydroxypropyl
methylcellulose), and acetylated monoglyceride. The tablets are imprinted using
a water-soluble black ink.
WELCHOL for Oral Suspension is a citrus-flavored, white to
pale yellow powder containing yellow granules packaged in single-dose packets
containing either 1.875 gram or 3.75 gram colesevelam hydrochloride. In
addition, each packet contains the following inactive ingredients: lemon
flavor, orange flavor, propylene glycol alginate, simethicone, aspartame,
citric acid, medium chain triglycerides, and magnesium trisilicate.
PHENYLKETONURICS: WELCHOL for Oral Suspension
contains 24 mg phenylalanine per 1.875 gram dose and 48 mg phenylalanine per
3.75 gram dose.Last reviewed on RxList: 10/27/2009




Welchol Drug Description
WELCHOL
(colesevelam hydrochloride)
DRUG DESCRIPTION



What are the possible side effects of colesevelam (Welchol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using colesevelam and call your doctor at once if you have severe constipation or stomach pain.
Less serious side effects may include:

constipation;
nausea, upset stomach pain, gas, indigestion;
feeling weak or tired;
muscle weakness; or
runny nose, sore...
Read All Potential Side Effects for Welchol »




WELCHOL (colesevelam hydrochloride) is a non-absorbed,
polymeric, lipid-lowering and glucose-lowering agent intended for oral
administration. Colesevelam hydrochloride is a high-capacity bile acid-binding
molecule.
Colesevelam hydrochloride is poly(allylamine hydrochloride)
cross-linked with epichlorohydrin and alkylated with 1-bromodecane and
(6-bromohexyl)-trimethylammonium bromide. The chemical name (IUPAC) of
colesevelam hydrochloride is allylamine polymer with 1-chloro-2,3-epoxypropane,
[6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine,
hydrochloride. The chemical structure of colesevelam hydrochloride is
represented by the following formula:








wherein (a) represents allyl amine monomer units that have
not been alkylated by either of the 1-bromodecane or
(6-bromohexyl)-trimethylammonium bromide alkylating agents or cross-linked by
epichlorohydrin; (b) represents allyl amine units that have undergone
crosslinking with epichlorohydrin; (c) represents allyl amine units that have
been alkylated with a decyl group; (d) represents allyl amine units that have
been alkylated with a (6-trimethylammonium) hexyl group, and m represents a
number ≥ 100 to indicate an extended polymer network. A small amount of
the amines are dialkylated, and are not depicted in the formula above. No
regular order of the groups is implied by the structure; cross-linking and
alkylation are expected to occur randomly along the polymer chains. A large
amount of the amines are protonated. The polymer is depicted in the
hydrochloride form; a small amount of the halides are bromide. Colesevelam
hydrochloride is hydrophilic and insoluble in water.
WELCHOL Tablets are an off-white, oval, film-coated, solid
tablet containing 625 mg colesevelam hydrochloride. In addition, each tablet
contains the following inactive ingredients: magnesium stearate,
microcrystalline cellulose, silicon dioxide, HPMC (hydroxypropyl
methylcellulose), and acetylated monoglyceride. The tablets are imprinted using
a water-soluble black ink.
WELCHOL for Oral Suspension is a citrus-flavored, white to
pale yellow powder containing yellow granules packaged in single-dose packets
containing either 1.875 gram or 3.75 gram colesevelam hydrochloride. In
addition, each packet contains the following inactive ingredients: lemon
flavor, orange flavor, propylene glycol alginate, simethicone, aspartame,
citric acid, medium chain triglycerides, and magnesium trisilicate.
PHENYLKETONURICS: WELCHOL for Oral Suspension
contains 24 mg phenylalanine per 1.875 gram dose and 48 mg phenylalanine per
3.75 gram dose.Last reviewed on RxList: 10/27/2009




Welchol Drug Description
WELCHOL
(colesevelam hydrochloride)
DRUG DESCRIPTION



What are the possible side effects of colesevelam (Welchol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using colesevelam and call your doctor at once if you have severe constipation or stomach pain.
Less serious side effects may include:

constipation;
nausea, upset stomach pain, gas, indigestion;
feeling weak or tired;
muscle weakness; or
runny nose, sore...
Read All Potential Side Effects for Welchol »




WELCHOL (colesevelam hydrochloride) is a non-absorbed,
polymeric, lipid-lowering and glucose-lowering agent intended for oral
administration. Colesevelam hydrochloride is a high-capacity bile acid-binding
molecule.
Colesevelam hydrochloride is poly(allylamine hydrochloride)
cross-linked with epichlorohydrin and alkylated with 1-bromodecane and
(6-bromohexyl)-trimethylammonium bromide. The chemical name (IUPAC) of
colesevelam hydrochloride is allylamine polymer with 1-chloro-2,3-epoxypropane,
[6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine,
hydrochloride. The chemical structure of colesevelam hydrochloride is
represented by the following formula:








wherein (a) represents allyl amine monomer units that have
not been alkylated by either of the 1-bromodecane or
(6-bromohexyl)-trimethylammonium bromide alkylating agents or cross-linked by
epichlorohydrin; (b) represents allyl amine units that have undergone
crosslinking with epichlorohydrin; (c) represents allyl amine units that have
been alkylated with a decyl group; (d) represents allyl amine units that have
been alkylated with a (6-trimethylammonium) hexyl group, and m represents a
number ≥ 100 to indicate an extended polymer network. A small amount of
the amines are dialkylated, and are not depicted in the formula above. No
regular order of the groups is implied by the structure; cross-linking and
alkylation are expected to occur randomly along the polymer chains. A large
amount of the amines are protonated. The polymer is depicted in the
hydrochloride form; a small amount of the halides are bromide. Colesevelam
hydrochloride is hydrophilic and insoluble in water.
WELCHOL Tablets are an off-white, oval, film-coated, solid
tablet containing 625 mg colesevelam hydrochloride. In addition, each tablet
contains the following inactive ingredients: magnesium stearate,
microcrystalline cellulose, silicon dioxide, HPMC (hydroxypropyl
methylcellulose), and acetylated monoglyceride. The tablets are imprinted using
a water-soluble black ink.
WELCHOL for Oral Suspension is a citrus-flavored, white to
pale yellow powder containing yellow granules packaged in single-dose packets
containing either 1.875 gram or 3.75 gram colesevelam hydrochloride. In
addition, each packet contains the following inactive ingredients: lemon
flavor, orange flavor, propylene glycol alginate, simethicone, aspartame,
citric acid, medium chain triglycerides, and magnesium trisilicate.
PHENYLKETONURICS: WELCHOL for Oral Suspension
contains 24 mg phenylalanine per 1.875 gram dose and 48 mg phenylalanine per
3.75 gram dose.Last reviewed on RxList: 10/27/2009




Welchol Drug Description
WELCHOL
(colesevelam hydrochloride)
DRUG DESCRIPTION



What are the possible side effects of colesevelam (Welchol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using colesevelam and call your doctor at once if you have severe constipation or stomach pain.
Less serious side effects may include:

constipation;
nausea, upset stomach pain, gas, indigestion;
feeling weak or tired;
muscle weakness; or
runny nose, sore...
Read All Potential Side Effects for Welchol »




WELCHOL (colesevelam hydrochloride) is a non-absorbed,
polymeric, lipid-lowering and glucose-lowering agent intended for oral
administration. Colesevelam hydrochloride is a high-capacity bile acid-binding
molecule.
Colesevelam hydrochloride is poly(allylamine hydrochloride)
cross-linked with epichlorohydrin and alkylated with 1-bromodecane and
(6-bromohexyl)-trimethylammonium bromide. The chemical name (IUPAC) of
colesevelam hydrochloride is allylamine polymer with 1-chloro-2,3-epoxypropane,
[6-(allylamino)-hexyl]trimethylammonium chloride and N-allyldecylamine,
hydrochloride. The chemical structure of colesevelam hydrochloride is
represented by the following formula:








wherein (a) represents allyl amine monomer units that have
not been alkylated by either of the 1-bromodecane or
(6-bromohexyl)-trimethylammonium bromide alkylating agents or cross-linked by
epichlorohydrin; (b) represents allyl amine units that have undergone
crosslinking with epichlorohydrin; (c) represents allyl amine units that have
been alkylated with a decyl group; (d) represents allyl amine units that have
been alkylated with a (6-trimethylammonium) hexyl group, and m represents a
number ≥ 100 to indicate an extended polymer network. A small amount of
the amines are dialkylated, and are not depicted in the formula above. No
regular order of the groups is implied by the structure; cross-linking and
alkylation are expected to occur randomly along the polymer chains. A large
amount of the amines are protonated. The polymer is depicted in the
hydrochloride form; a small amount of the halides are bromide. Colesevelam
hydrochloride is hydrophilic and insoluble in water.
WELCHOL Tablets are an off-white, oval, film-coated, solid
tablet containing 625 mg colesevelam hydrochloride. In addition, each tablet
contains the following inactive ingredients: magnesium stearate,
microcrystalline cellulose, silicon dioxide, HPMC (hydroxypropyl
methylcellulose), and acetylated monoglyceride. The tablets are imprinted using
a water-soluble black ink.
WELCHOL for Oral Suspension is a citrus-flavored, white to
pale yellow powder containing yellow granules packaged in single-dose packets
containing either 1.875 gram or 3.75 gram colesevelam hydrochloride. In
addition, each packet contains the following inactive ingredients: lemon
flavor, orange flavor, propylene glycol alginate, simethicone, aspartame,
citric acid, medium chain triglycerides, and magnesium trisilicate.
PHENYLKETONURICS: WELCHOL for Oral Suspension
contains 24 mg phenylalanine per 1.875 gram dose and 48 mg phenylalanine per
3.75 gram dose.Last reviewed on RxList: 10/27/2009





Other reviews about Colesevelam Hcl on wordpress

Daiichi Sankyo, Inc. Announces Filing Of Supplemental New Drug Application For WelChol In The Treatment Of Type 2 Diabetes Mellitus
  by rognar
Daiichi Sankyo, Inc. announced today that it has filed a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration (FDA) for WelChol(R) […]


New Study Confirms WelChol Improves Glycemic Control In Patients With Uncontrolled Type 2 Diabetes Mellitus On Insulin
  by rognar
Data presented today at the American Heart Association's (AHA) Scientific Sessions 2006 in Chicago demonstrated that WelChol(R) (colesevelam HCl), when added to insulin in […]


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Colesevelam (Welchol) Treatment for Type 2 Diabetes
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[caption id="attachment_177" align="alignleft" width="177" caption="Are you sick and tired of taking pills?"][/caption] David Mendosa's May 20, 2009, blog post at HealthCentral.com brought to my attention a little-used diabetes drug, colesevelam […]


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Other reviews about Colesevelam Hcl on web:

Learn about the prescription medication Welchol (Colesevelam Hcl), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Welchol (Colesevelam Hcl) Drug Information: Uses, Side Effects ...


N-prop-2-enyldecan-1-amine; trimethyl-[6-(prop-2-enylamino)hexyl]azanium; prop-2-en-1-amine; 2-(chloromethyl)oxirane; hydrogen chloride; chloride. How it works. Colesevelam is part of ... Colesevelam - Wikipedia, the free encyclopedia


1. Expert Opin Pharmacother. 2003 May;4(5):779-90. Colesevelam HCl: a non-systemic lipid-altering drug. Bays H, Dujovne C. Kansas Foundation for Clinical Pharmacology, Radiant ... Colesevelam HCl: a non-systemic lipid-altering drug.


Colesevelam Hydrochloride professional patient advice. Specific and up to date information about Colesevelam Hydrochloride. Complete Colesevelam Hydrochloride information from Drugs.com


Learn about managing your high LDL cholesterol and/or type 2 diabetes with Welchol. Welchol Is the Only Treatment That Reduces Both A1C & LDL-C


Consumer information about the medication COLESEVELAM - ORAL (Welchol), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the ... COLESEVELAM - ORAL (Welchol) side effects, medical uses, and drug ...


Daiichi Sankyo, Inc., announced that the United States Food and Drug Administration (FDA) has approved Welchol(TM) (colesevelam HCl) to improve glycemic control (measured as ... Welchol(TM) (colesevelam HCl) Receives FDA Approval To Reduce ...


Our hypothesis is that the medication approved for treatment of high blood cholesterol levels, Colesevelam HCl (WELCHOL), decreases colonic transit and permeability in patients ... Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit ...


Colesevelam Hcl Side Effects. Colesevelam, sold as Welchol, is prescribed in the treatment of both high cholesterol and type II diabetes. It functions by combining with particles ... Colesevelam Hcl Side Effects | LIVESTRONG.COM


daiichi sankyo, inc. release: new study demonstrates colesevelam hcl lowers both a1c and ldl cholest ... Jun 23 2007; daiichi sankyo, inc. announces filing of ... COLESEVELAM HYDROCHLORIDE





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