Reviews Clinoril


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Clinoril Drug Description
CLINORIL®
(sulindac) Tablets


Cardiovascular Risk

NSAIDs may cause an increased risk of serious cardiovascular thrombotic
events, myocardial infarction, and stroke, which can be fatal. This risk may
increase with duration of use. Patients with cardiovascular disease or risk
factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
CLINORIL is contraindicated for the treatment of peri-operative pain in
the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

NSAIDs cause an increased risk of serious gastrointestinal adverse events
including bleeding, ulceration, and perforation of the stomach or intestines,
which can be fatal. These events can occur at any time during use and without
warning symptoms. Elderly patients are at greater risk for serious gastrointestinal
events. (See WARNINGS.)

DRUG DESCRIPTION



What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking sulindac and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
urinating...
Read All Potential Side Effects for Clinoril »




Sulindac is a non-steroidal, anti-inflammatory indene derivative designated
chemically as (Z)-5-fluoro2-methyl-1-[[p-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic
acid. It is not a salicylate, pyrazolone or propionic acid derivative. Its empirical
formula is C20H17FO3S, with a molecular weight
of 356.42. Sulindac, a yellow crystalline compound, is a weak organic acid practically
insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers
of pH 6 or higher.
CLINORIL (Sulindac) is available in 200 mg tablets for oral administration.
Each tablet contains the following inactive ingredients: cellulose, magnesium
stearate, starch.
Following absorption, sulindac undergoes two major biotransformations - reversible
reduction to the sulfide metabolite, and irreversible oxidation to the sulfone
metabolite. Available evidence indicates that the biological activity resides
with the sulfide metabolite.
The structural formulas of sulindac and its metabolites are:








Last reviewed on RxList: 7/1/2010




Clinoril Drug Description
CLINORIL®
(sulindac) Tablets


Cardiovascular Risk

NSAIDs may cause an increased risk of serious cardiovascular thrombotic
events, myocardial infarction, and stroke, which can be fatal. This risk may
increase with duration of use. Patients with cardiovascular disease or risk
factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
CLINORIL is contraindicated for the treatment of peri-operative pain in
the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

NSAIDs cause an increased risk of serious gastrointestinal adverse events
including bleeding, ulceration, and perforation of the stomach or intestines,
which can be fatal. These events can occur at any time during use and without
warning symptoms. Elderly patients are at greater risk for serious gastrointestinal
events. (See WARNINGS.)

DRUG DESCRIPTION



What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking sulindac and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
urinating...
Read All Potential Side Effects for Clinoril »




Sulindac is a non-steroidal, anti-inflammatory indene derivative designated
chemically as (Z)-5-fluoro2-methyl-1-[[p-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic
acid. It is not a salicylate, pyrazolone or propionic acid derivative. Its empirical
formula is C20H17FO3S, with a molecular weight
of 356.42. Sulindac, a yellow crystalline compound, is a weak organic acid practically
insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers
of pH 6 or higher.
CLINORIL (Sulindac) is available in 200 mg tablets for oral administration.
Each tablet contains the following inactive ingredients: cellulose, magnesium
stearate, starch.
Following absorption, sulindac undergoes two major biotransformations - reversible
reduction to the sulfide metabolite, and irreversible oxidation to the sulfone
metabolite. Available evidence indicates that the biological activity resides
with the sulfide metabolite.
The structural formulas of sulindac and its metabolites are:








Last reviewed on RxList: 7/1/2010




Clinoril Drug Description
CLINORIL®
(sulindac) Tablets


Cardiovascular Risk

NSAIDs may cause an increased risk of serious cardiovascular thrombotic
events, myocardial infarction, and stroke, which can be fatal. This risk may
increase with duration of use. Patients with cardiovascular disease or risk
factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
CLINORIL is contraindicated for the treatment of peri-operative pain in
the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

NSAIDs cause an increased risk of serious gastrointestinal adverse events
including bleeding, ulceration, and perforation of the stomach or intestines,
which can be fatal. These events can occur at any time during use and without
warning symptoms. Elderly patients are at greater risk for serious gastrointestinal
events. (See WARNINGS.)

DRUG DESCRIPTION



What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking sulindac and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
urinating...
Read All Potential Side Effects for Clinoril »




Sulindac is a non-steroidal, anti-inflammatory indene derivative designated
chemically as (Z)-5-fluoro2-methyl-1-[[p-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic
acid. It is not a salicylate, pyrazolone or propionic acid derivative. Its empirical
formula is C20H17FO3S, with a molecular weight
of 356.42. Sulindac, a yellow crystalline compound, is a weak organic acid practically
insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers
of pH 6 or higher.
CLINORIL (Sulindac) is available in 200 mg tablets for oral administration.
Each tablet contains the following inactive ingredients: cellulose, magnesium
stearate, starch.
Following absorption, sulindac undergoes two major biotransformations - reversible
reduction to the sulfide metabolite, and irreversible oxidation to the sulfone
metabolite. Available evidence indicates that the biological activity resides
with the sulfide metabolite.
The structural formulas of sulindac and its metabolites are:








Last reviewed on RxList: 7/1/2010




Clinoril Drug Description
CLINORIL®
(sulindac) Tablets


Cardiovascular Risk

NSAIDs may cause an increased risk of serious cardiovascular thrombotic
events, myocardial infarction, and stroke, which can be fatal. This risk may
increase with duration of use. Patients with cardiovascular disease or risk
factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
CLINORIL is contraindicated for the treatment of peri-operative pain in
the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

NSAIDs cause an increased risk of serious gastrointestinal adverse events
including bleeding, ulceration, and perforation of the stomach or intestines,
which can be fatal. These events can occur at any time during use and without
warning symptoms. Elderly patients are at greater risk for serious gastrointestinal
events. (See WARNINGS.)

DRUG DESCRIPTION



What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking sulindac and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
urinating...
Read All Potential Side Effects for Clinoril »




Sulindac is a non-steroidal, anti-inflammatory indene derivative designated
chemically as (Z)-5-fluoro2-methyl-1-[[p-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic
acid. It is not a salicylate, pyrazolone or propionic acid derivative. Its empirical
formula is C20H17FO3S, with a molecular weight
of 356.42. Sulindac, a yellow crystalline compound, is a weak organic acid practically
insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers
of pH 6 or higher.
CLINORIL (Sulindac) is available in 200 mg tablets for oral administration.
Each tablet contains the following inactive ingredients: cellulose, magnesium
stearate, starch.
Following absorption, sulindac undergoes two major biotransformations - reversible
reduction to the sulfide metabolite, and irreversible oxidation to the sulfone
metabolite. Available evidence indicates that the biological activity resides
with the sulfide metabolite.
The structural formulas of sulindac and its metabolites are:








Last reviewed on RxList: 7/1/2010




Clinoril Drug Description
CLINORIL®
(sulindac) Tablets


Cardiovascular Risk

NSAIDs may cause an increased risk of serious cardiovascular thrombotic
events, myocardial infarction, and stroke, which can be fatal. This risk may
increase with duration of use. Patients with cardiovascular disease or risk
factors for cardiovascular disease may be at greater risk. (See WARNINGS.)
CLINORIL is contraindicated for the treatment of peri-operative pain in
the setting of coronary artery bypass graft (CABG) surgery (see WARNINGS).

Gastrointestinal Risk

NSAIDs cause an increased risk of serious gastrointestinal adverse events
including bleeding, ulceration, and perforation of the stomach or intestines,
which can be fatal. These events can occur at any time during use and without
warning symptoms. Elderly patients are at greater risk for serious gastrointestinal
events. (See WARNINGS.)

DRUG DESCRIPTION



What are the possible side effects of sulindac (Clinoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking sulindac and seek medical attention or call your doctor at once if you have any of these serious side effects:

chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
urinating...
Read All Potential Side Effects for Clinoril »




Sulindac is a non-steroidal, anti-inflammatory indene derivative designated
chemically as (Z)-5-fluoro2-methyl-1-[[p-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic
acid. It is not a salicylate, pyrazolone or propionic acid derivative. Its empirical
formula is C20H17FO3S, with a molecular weight
of 356.42. Sulindac, a yellow crystalline compound, is a weak organic acid practically
insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers
of pH 6 or higher.
CLINORIL (Sulindac) is available in 200 mg tablets for oral administration.
Each tablet contains the following inactive ingredients: cellulose, magnesium
stearate, starch.
Following absorption, sulindac undergoes two major biotransformations - reversible
reduction to the sulfide metabolite, and irreversible oxidation to the sulfone
metabolite. Available evidence indicates that the biological activity resides
with the sulfide metabolite.
The structural formulas of sulindac and its metabolites are:








Last reviewed on RxList: 7/1/2010





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Other reviews about Clinoril on web:

Learn about the prescription medication Clinoril (Sulindac), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Clinoril (Sulindac) Drug Information: Uses, Side Effects, Drug ...


Clinoril information from Drugs.com. Clinoril, a nonsteroidal anti-inflammatory drug, is used to relieve the inflammation, swelling, stiffness, and joint pain associated with ... Clinoril patient advice including side effects


Explains the medication sulindac (Clinoril), a drug used for the treatment of inflammation and pain that results from rheumatoid arthritis, tendinitis, bursitis, ankylosing ... sulindac (Clinoril) - drug class, medical uses, medication side ...


Clinoril is a drug that is used to relieve symptoms of arthritis and general pain, fever, or inflammation. This eMedTV segment explains the effects of the drug and offers ... Clinoril


All about Clinoril. View complete and up to date Clinoril information - part of the Drugs.com trusted medication database. Clinoril Facts and Comparisons at Drugs.com


Learn about Clinoril from the publishers of the Physicians Desk Reference. Find prescription drug information resources including interactions, side effects, symptoms, treatment ... Clinoril | Prescription Drug Information, Side Effects | PDRHealth


Clinoril side effects, dosage, and drug interactions. All accurate, up-to-date information is written for the consumer by healthcare professionals. Clinoril Oral Uses and How to Use


Sulindac is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class that is marketed in the UK & U.S. by Merck as Clinoril. Uses. Like other NSAIDs, it is useful in the ... Sulindac - Wikipedia, the free encyclopedia


Clin·o·ril (kl n-r l) A trademark for the drug sulindac. Clinoril, a trademark for a nonsteroidal antiinflammatory drug (sulindac). sulindac. Apo-Sulin (CA), Clinoril, Novo-Sundac (CA ... Clinoril - definition of Clinoril in the Medical dictionary - by ...


Find patient medical information for Clinoril Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Clinoril Oral : Uses, Side Effects, Interactions, Pictures ...





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