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Cervarix Drug Description
CERVARIX
[Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Suspension
for Intramuscular Injection
DRUG DESCRIPTION
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant]
is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant
L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types
16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant
Baculovirus expression vector system in a serum-free culture media composed
of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following
replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni
insect cells, the L1 protein accumulates in the cytoplasm of the cells. The
L1 proteins are released by cell disruption and purified by a series of chromatographic
and filtration methods. Assembly of the L1 proteins into virus-like particles
(VLPs) occurs at the end of the purification process. The purified, non-infectious
VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system,
AS04, is composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed
on to aluminum (as hydroxide salt).
CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.
CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose
is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type
18 L1 protein, 50 mcg of the 3-O-desacyl-4'-monophosphoryl lipid A (MPL),
and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride
and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain
residual amounts of insect cell and viral protein ( < 40 ng) and bacterial
cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not
contain a preservative.
Last reviewed on RxList: 10/30/2009




Cervarix Drug Description
CERVARIX
[Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Suspension
for Intramuscular Injection
DRUG DESCRIPTION
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant]
is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant
L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types
16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant
Baculovirus expression vector system in a serum-free culture media composed
of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following
replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni
insect cells, the L1 protein accumulates in the cytoplasm of the cells. The
L1 proteins are released by cell disruption and purified by a series of chromatographic
and filtration methods. Assembly of the L1 proteins into virus-like particles
(VLPs) occurs at the end of the purification process. The purified, non-infectious
VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system,
AS04, is composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed
on to aluminum (as hydroxide salt).
CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.
CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose
is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type
18 L1 protein, 50 mcg of the 3-O-desacyl-4'-monophosphoryl lipid A (MPL),
and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride
and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain
residual amounts of insect cell and viral protein ( < 40 ng) and bacterial
cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not
contain a preservative.
Last reviewed on RxList: 10/30/2009




Cervarix Drug Description
CERVARIX
[Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Suspension
for Intramuscular Injection
DRUG DESCRIPTION
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant]
is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant
L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types
16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant
Baculovirus expression vector system in a serum-free culture media composed
of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following
replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni
insect cells, the L1 protein accumulates in the cytoplasm of the cells. The
L1 proteins are released by cell disruption and purified by a series of chromatographic
and filtration methods. Assembly of the L1 proteins into virus-like particles
(VLPs) occurs at the end of the purification process. The purified, non-infectious
VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system,
AS04, is composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed
on to aluminum (as hydroxide salt).
CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.
CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose
is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type
18 L1 protein, 50 mcg of the 3-O-desacyl-4'-monophosphoryl lipid A (MPL),
and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride
and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain
residual amounts of insect cell and viral protein ( < 40 ng) and bacterial
cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not
contain a preservative.
Last reviewed on RxList: 10/30/2009




Cervarix Drug Description
CERVARIX
[Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Suspension
for Intramuscular Injection
DRUG DESCRIPTION
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant]
is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant
L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types
16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant
Baculovirus expression vector system in a serum-free culture media composed
of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following
replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni
insect cells, the L1 protein accumulates in the cytoplasm of the cells. The
L1 proteins are released by cell disruption and purified by a series of chromatographic
and filtration methods. Assembly of the L1 proteins into virus-like particles
(VLPs) occurs at the end of the purification process. The purified, non-infectious
VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system,
AS04, is composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed
on to aluminum (as hydroxide salt).
CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.
CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose
is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type
18 L1 protein, 50 mcg of the 3-O-desacyl-4'-monophosphoryl lipid A (MPL),
and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride
and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain
residual amounts of insect cell and viral protein ( < 40 ng) and bacterial
cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not
contain a preservative.
Last reviewed on RxList: 10/30/2009




Cervarix Drug Description
CERVARIX
[Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant] Suspension
for Intramuscular Injection
DRUG DESCRIPTION
CERVARIX [Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant]
is a non-infectious recombinant, AS04-adjuvanted vaccine that contains recombinant
L1 protein, the major antigenic protein of the capsid, of oncogenic HPV types
16 and 18. The L1 proteins are produced in separate bioreactors using the recombinant
Baculovirus expression vector system in a serum-free culture media composed
of chemically-defined lipids, vitamins, amino acids, and mineral salts. Following
replication of the L1 encoding recombinant Baculovirus in Trichoplusia ni
insect cells, the L1 protein accumulates in the cytoplasm of the cells. The
L1 proteins are released by cell disruption and purified by a series of chromatographic
and filtration methods. Assembly of the L1 proteins into virus-like particles
(VLPs) occurs at the end of the purification process. The purified, non-infectious
VLPs are then adsorbed on to aluminum (as hydroxide salt). The adjuvant system,
AS04, is composed of 3-O-desacyl-4'-monophosphoryl lipid A (MPL) adsorbed
on to aluminum (as hydroxide salt).
CERVARIX is prepared by combining the adsorbed VLPs of each HPV type together with the AS04 adjuvant system in sodium chloride, sodium dihydrogen phosphate dihydrate, and Water for Injection.
CERVARIX is a sterile suspension for intramuscular injection. Each 0.5-mL dose
is formulated to contain 20 mcg of HPV type 16 L1 protein, 20 mcg of HPV type
18 L1 protein, 50 mcg of the 3-O-desacyl-4'-monophosphoryl lipid A (MPL),
and 0.5 mg of aluminum hydroxide. Each dose also contains 4.4 mg of sodium chloride
and 0.624 mg of sodium dihydrogen phosphate dihydrate. Each dose may also contain
residual amounts of insect cell and viral protein ( < 40 ng) and bacterial
cell protein ( < 150 ng) from the manufacturing process. CERVARIX does not
contain a preservative.
Last reviewed on RxList: 10/30/2009





Other reviews about Cervarix on wordpress

New HPV Vaccine
  by ksully11
We’ve all heard of Gardasil, the vaccine against HPV, or human papilloma virus. But you may not have heard of Cervarix, a newly approved vaccine against HPV. On September 9th, the […]


Cervarix Approved to Help Prevent Cervical Cancer
  by timeinctemp
FRIDAY, Oct. 16 (HealthDay News) — GlaxoSmithKline's Cervarix vaccine has been approved by the U.S. Food and Drug Administration to prevent the leading cause of cervical cancer, the […]


FDA Approves Cervarix for Cervical Cancer Prevention
  by lrodriguezmd
The Food and Drug administration has approved the use of Cervarix for the prevention of cervical cancer. This vaccine contains HPV Types 16 and 18 which are linked […]


Cervarix
  by sheptalk
Cervarix, a new vaccine for HPV (Human Papilloma Virus) has recently been approved by the FDA. It will enter the HPV vaccine market as a competitor to […]


To Jab or not to Jab
  by milybaby
Cervical cancer immunisation has been the latest hot topic among women lately after a reported serius side effect of Gardasil which resulted in the death of a young […]


Gardasil vs Cervarix
  by milybaby
There are pretty much talk about the 2 cervical cancer vaccines. Many of my friends were asking me if 1 is superior to the other and why the […]


Cervarix Proves Effective Against HPV for Over 6 Years
  by timeinctemp
WEDNESDAY, Dec. 2 (HealthDay News) — The human papillomavirus (HPV) vaccine Cervarix protects women from infection for longer than six years, new research has found. The vaccine guards against […]


Cervarix Vaccine
  by muffet
Cervarix is a vaccine against the human papilloma virus (HPV). This virus is a sexually-transmitted infection that can cause genital warts, pre-cancerous abnormalities of cells in the female […]


Health Canada Approves Cervarix - HPV Vaccine
  by merlinx9
A second vaccine to protect against human papillomavirus, or HPV, has been approved for use in Canada. GlaxoSmithKline's vaccine Cervarix is intended to protect against cervical cancers and abnormal […]


Orange Models Job! CERVARIX Vaccine campaign!
  by orangemodels
JOB! PRINT AD Congrats to our model Marissa Ali for booking the latest Cervarix Vaccine Campaign. The Campaign will launch very soon in the Spring 2010! We are very […]



Other reviews about Cervarix on web:

Cervarix is a vaccine against certain types of cancer-causing human papillomavirus (HPV). Cervarix is designed to prevent infection from HPV types 16 and 18, which currently cause ... Cervarix - Wikipedia, the free encyclopedia


Find information about CERVARIX, a cervical cancer vaccine indicated to prevent human papillomavirus (HPV) 16 and 18. See Important Safety Information. Cervical Cancer Vaccine | CERVARIX [Human Papillomavirus Bivalent ...


Cervarix (human papillomavirus vaccine) is used for prevention of cervical cancer caused by human papillomavirus (HPV). Includes Cervarix side effects, interactions and indications Cervarix Information from Drugs.com


Help X out cervical cancer. This website has been designed by GlaxoSmithKline. GSK - Cervarix


Accurate, FDA approved Cervarix information for healthcare professionals and patients - brought to you by Drugs.com. Cervarix Official FDA information, side effects and uses.


Learn more about Cervarix, an HPV vaccine that is projected to be approved by the FDA in the fall of 2006. Cervarix offers an alternive to Gardasil, the HPV vaccine already ... Cervarix HPV Vaccine - Facts About Cervarix -


Learn about Cervarix, an HPV vaccine that may compete with Gardasil. Cervarix


FDA approves Cervarix, GlaxoSmithKline’s cervical cancer vaccine ... This press release is intended for business journalists and analysts/investors. FDA approves Cervarix, GlaxoSmithKline’s cervical cancer vaccine


Product Approval (Approval Letter, Package Insert) ... Cervarix. Proper Name: Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant Cervarix


Learn more about Cervarix. Find the Web's best health guides, medical reports, news, videos and tools for Cervarix. Share Cervarix experiences and get advice from experts. Cervarix Overview - References, Advice, News, Videos, Coping & Support





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