Reviews Ceftriaxone


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Ceftriaxone Drug Description
Ceftriaxone for Injection and Dextrose Injection
(ceftriaxone sodium and dextrose injection (diluent) in the DUPLEX sterile container)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection and Dextrose Injection and other antibacterial drugs, Ceftriaxone for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
Ceftriaxone for Injection and Dextrose Injection is a sterile, nonpyrogenic,
single use, packaged combination of Ceftriaxone Sodium and Dextrose Injection
(diluent) in the DUPLEX sterile container. The DUPLEX Container is a flexible
dual chamber container.
The drug chamber is filled with ceftriaxone sodium, a sterile, semisynthetic,
broad-spectrum cephalosporin antibiotic for intravenous administration. Ceftriaxone
sodium is (6R,7R)-7-[2-(2- Amino-4-thiazolyl)glyoxylamido]-8-oxo-3- [[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-
yl)thio]methyl] -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,72-(Z)-(0-methyloxime),
disodium salt, sesquaterhydrate.
Ceftriaxone Sodium has the following structural formula:







The chemical formula of ceftriaxone sodium is C18H16N8Na207S3•3.5H20,
representing a molecular weight of 661.60.
Ceftriaxone Sodium is supplied as a dry powder form equivalent to either..1
g or 2 g of ceftriaxone. Ceftriaxone Sodium is a white to yellowish-orange crystalline
powder which is readily soluble in water, sparingly soluble in methanol and
very slightly soluble in ethanol. The pH of a 1% aqueous solution is approximately
6.7. The color of Ceftriaxone Sodium solutions ranges from light yellow to amber,
depending on the length of storage and concentration. Ceftriaxone Sodium contains
approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity.
The diluent chamber contains Dextrose Injection. The concentration of Hydrous
Dextrose in Water for Injection USP has been adjusted to render the reconstituted
drug product iso-osmotic. Dextrose USP has been added to adjust osmolality (approximately
1.87 g and 1.11 g to 1 g and 2 g dosages, respectively). Dextrose Injection
is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.
Hydrous Dextrose USP has the following structural (molecular) formula:







The molecular weight of Hydrous Dextrose USP is 198.17.
After removing the peelable foil strip, activating the seals, and thoroughly
mixing, the reconstituted drug product is Intended for single intravenous use.
When reconstituted, the approximate osmolality for the reconstituted solution
for Ceftriaxone for Injection and Dextrose Injection is 290 mOsmol/kg.
The DUPLEX Container is Latex-free, PVC-free, and DEHP-free.
The DUPLEX dual chamber container is made from a specially formulated material.
The product (diluent and drug) contact layer is a mixture of thermoplastic rubber
and a polypropylene ethylene copolymer that contains no plasticizers. The safety
of the container system is supported by USP biological evaluation procedures.Last reviewed on RxList: 10/3/2007




Ceftriaxone Drug Description
Ceftriaxone for Injection and Dextrose Injection
(ceftriaxone sodium and dextrose injection (diluent) in the DUPLEX sterile container)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection and Dextrose Injection and other antibacterial drugs, Ceftriaxone for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
Ceftriaxone for Injection and Dextrose Injection is a sterile, nonpyrogenic,
single use, packaged combination of Ceftriaxone Sodium and Dextrose Injection
(diluent) in the DUPLEX sterile container. The DUPLEX Container is a flexible
dual chamber container.
The drug chamber is filled with ceftriaxone sodium, a sterile, semisynthetic,
broad-spectrum cephalosporin antibiotic for intravenous administration. Ceftriaxone
sodium is (6R,7R)-7-[2-(2- Amino-4-thiazolyl)glyoxylamido]-8-oxo-3- [[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-
yl)thio]methyl] -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,72-(Z)-(0-methyloxime),
disodium salt, sesquaterhydrate.
Ceftriaxone Sodium has the following structural formula:







The chemical formula of ceftriaxone sodium is C18H16N8Na207S3•3.5H20,
representing a molecular weight of 661.60.
Ceftriaxone Sodium is supplied as a dry powder form equivalent to either..1
g or 2 g of ceftriaxone. Ceftriaxone Sodium is a white to yellowish-orange crystalline
powder which is readily soluble in water, sparingly soluble in methanol and
very slightly soluble in ethanol. The pH of a 1% aqueous solution is approximately
6.7. The color of Ceftriaxone Sodium solutions ranges from light yellow to amber,
depending on the length of storage and concentration. Ceftriaxone Sodium contains
approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity.
The diluent chamber contains Dextrose Injection. The concentration of Hydrous
Dextrose in Water for Injection USP has been adjusted to render the reconstituted
drug product iso-osmotic. Dextrose USP has been added to adjust osmolality (approximately
1.87 g and 1.11 g to 1 g and 2 g dosages, respectively). Dextrose Injection
is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.
Hydrous Dextrose USP has the following structural (molecular) formula:







The molecular weight of Hydrous Dextrose USP is 198.17.
After removing the peelable foil strip, activating the seals, and thoroughly
mixing, the reconstituted drug product is Intended for single intravenous use.
When reconstituted, the approximate osmolality for the reconstituted solution
for Ceftriaxone for Injection and Dextrose Injection is 290 mOsmol/kg.
The DUPLEX Container is Latex-free, PVC-free, and DEHP-free.
The DUPLEX dual chamber container is made from a specially formulated material.
The product (diluent and drug) contact layer is a mixture of thermoplastic rubber
and a polypropylene ethylene copolymer that contains no plasticizers. The safety
of the container system is supported by USP biological evaluation procedures.Last reviewed on RxList: 10/3/2007




Ceftriaxone Drug Description
Ceftriaxone for Injection and Dextrose Injection
(ceftriaxone sodium and dextrose injection (diluent) in the DUPLEX sterile container)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection and Dextrose Injection and other antibacterial drugs, Ceftriaxone for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
Ceftriaxone for Injection and Dextrose Injection is a sterile, nonpyrogenic,
single use, packaged combination of Ceftriaxone Sodium and Dextrose Injection
(diluent) in the DUPLEX sterile container. The DUPLEX Container is a flexible
dual chamber container.
The drug chamber is filled with ceftriaxone sodium, a sterile, semisynthetic,
broad-spectrum cephalosporin antibiotic for intravenous administration. Ceftriaxone
sodium is (6R,7R)-7-[2-(2- Amino-4-thiazolyl)glyoxylamido]-8-oxo-3- [[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-
yl)thio]methyl] -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,72-(Z)-(0-methyloxime),
disodium salt, sesquaterhydrate.
Ceftriaxone Sodium has the following structural formula:







The chemical formula of ceftriaxone sodium is C18H16N8Na207S3•3.5H20,
representing a molecular weight of 661.60.
Ceftriaxone Sodium is supplied as a dry powder form equivalent to either..1
g or 2 g of ceftriaxone. Ceftriaxone Sodium is a white to yellowish-orange crystalline
powder which is readily soluble in water, sparingly soluble in methanol and
very slightly soluble in ethanol. The pH of a 1% aqueous solution is approximately
6.7. The color of Ceftriaxone Sodium solutions ranges from light yellow to amber,
depending on the length of storage and concentration. Ceftriaxone Sodium contains
approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity.
The diluent chamber contains Dextrose Injection. The concentration of Hydrous
Dextrose in Water for Injection USP has been adjusted to render the reconstituted
drug product iso-osmotic. Dextrose USP has been added to adjust osmolality (approximately
1.87 g and 1.11 g to 1 g and 2 g dosages, respectively). Dextrose Injection
is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.
Hydrous Dextrose USP has the following structural (molecular) formula:







The molecular weight of Hydrous Dextrose USP is 198.17.
After removing the peelable foil strip, activating the seals, and thoroughly
mixing, the reconstituted drug product is Intended for single intravenous use.
When reconstituted, the approximate osmolality for the reconstituted solution
for Ceftriaxone for Injection and Dextrose Injection is 290 mOsmol/kg.
The DUPLEX Container is Latex-free, PVC-free, and DEHP-free.
The DUPLEX dual chamber container is made from a specially formulated material.
The product (diluent and drug) contact layer is a mixture of thermoplastic rubber
and a polypropylene ethylene copolymer that contains no plasticizers. The safety
of the container system is supported by USP biological evaluation procedures.Last reviewed on RxList: 10/3/2007




Ceftriaxone Drug Description
Ceftriaxone for Injection and Dextrose Injection
(ceftriaxone sodium and dextrose injection (diluent) in the DUPLEX sterile container)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection and Dextrose Injection and other antibacterial drugs, Ceftriaxone for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
Ceftriaxone for Injection and Dextrose Injection is a sterile, nonpyrogenic,
single use, packaged combination of Ceftriaxone Sodium and Dextrose Injection
(diluent) in the DUPLEX sterile container. The DUPLEX Container is a flexible
dual chamber container.
The drug chamber is filled with ceftriaxone sodium, a sterile, semisynthetic,
broad-spectrum cephalosporin antibiotic for intravenous administration. Ceftriaxone
sodium is (6R,7R)-7-[2-(2- Amino-4-thiazolyl)glyoxylamido]-8-oxo-3- [[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-
yl)thio]methyl] -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,72-(Z)-(0-methyloxime),
disodium salt, sesquaterhydrate.
Ceftriaxone Sodium has the following structural formula:







The chemical formula of ceftriaxone sodium is C18H16N8Na207S3•3.5H20,
representing a molecular weight of 661.60.
Ceftriaxone Sodium is supplied as a dry powder form equivalent to either..1
g or 2 g of ceftriaxone. Ceftriaxone Sodium is a white to yellowish-orange crystalline
powder which is readily soluble in water, sparingly soluble in methanol and
very slightly soluble in ethanol. The pH of a 1% aqueous solution is approximately
6.7. The color of Ceftriaxone Sodium solutions ranges from light yellow to amber,
depending on the length of storage and concentration. Ceftriaxone Sodium contains
approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity.
The diluent chamber contains Dextrose Injection. The concentration of Hydrous
Dextrose in Water for Injection USP has been adjusted to render the reconstituted
drug product iso-osmotic. Dextrose USP has been added to adjust osmolality (approximately
1.87 g and 1.11 g to 1 g and 2 g dosages, respectively). Dextrose Injection
is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.
Hydrous Dextrose USP has the following structural (molecular) formula:







The molecular weight of Hydrous Dextrose USP is 198.17.
After removing the peelable foil strip, activating the seals, and thoroughly
mixing, the reconstituted drug product is Intended for single intravenous use.
When reconstituted, the approximate osmolality for the reconstituted solution
for Ceftriaxone for Injection and Dextrose Injection is 290 mOsmol/kg.
The DUPLEX Container is Latex-free, PVC-free, and DEHP-free.
The DUPLEX dual chamber container is made from a specially formulated material.
The product (diluent and drug) contact layer is a mixture of thermoplastic rubber
and a polypropylene ethylene copolymer that contains no plasticizers. The safety
of the container system is supported by USP biological evaluation procedures.Last reviewed on RxList: 10/3/2007




Ceftriaxone Drug Description
Ceftriaxone for Injection and Dextrose Injection
(ceftriaxone sodium and dextrose injection (diluent) in the DUPLEX sterile container)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection and Dextrose Injection and other antibacterial drugs, Ceftriaxone for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
Ceftriaxone for Injection and Dextrose Injection is a sterile, nonpyrogenic,
single use, packaged combination of Ceftriaxone Sodium and Dextrose Injection
(diluent) in the DUPLEX sterile container. The DUPLEX Container is a flexible
dual chamber container.
The drug chamber is filled with ceftriaxone sodium, a sterile, semisynthetic,
broad-spectrum cephalosporin antibiotic for intravenous administration. Ceftriaxone
sodium is (6R,7R)-7-[2-(2- Amino-4-thiazolyl)glyoxylamido]-8-oxo-3- [[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-
yl)thio]methyl] -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,72-(Z)-(0-methyloxime),
disodium salt, sesquaterhydrate.
Ceftriaxone Sodium has the following structural formula:







The chemical formula of ceftriaxone sodium is C18H16N8Na207S3•3.5H20,
representing a molecular weight of 661.60.
Ceftriaxone Sodium is supplied as a dry powder form equivalent to either..1
g or 2 g of ceftriaxone. Ceftriaxone Sodium is a white to yellowish-orange crystalline
powder which is readily soluble in water, sparingly soluble in methanol and
very slightly soluble in ethanol. The pH of a 1% aqueous solution is approximately
6.7. The color of Ceftriaxone Sodium solutions ranges from light yellow to amber,
depending on the length of storage and concentration. Ceftriaxone Sodium contains
approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity.
The diluent chamber contains Dextrose Injection. The concentration of Hydrous
Dextrose in Water for Injection USP has been adjusted to render the reconstituted
drug product iso-osmotic. Dextrose USP has been added to adjust osmolality (approximately
1.87 g and 1.11 g to 1 g and 2 g dosages, respectively). Dextrose Injection
is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.
Hydrous Dextrose USP has the following structural (molecular) formula:







The molecular weight of Hydrous Dextrose USP is 198.17.
After removing the peelable foil strip, activating the seals, and thoroughly
mixing, the reconstituted drug product is Intended for single intravenous use.
When reconstituted, the approximate osmolality for the reconstituted solution
for Ceftriaxone for Injection and Dextrose Injection is 290 mOsmol/kg.
The DUPLEX Container is Latex-free, PVC-free, and DEHP-free.
The DUPLEX dual chamber container is made from a specially formulated material.
The product (diluent and drug) contact layer is a mixture of thermoplastic rubber
and a polypropylene ethylene copolymer that contains no plasticizers. The safety
of the container system is supported by USP biological evaluation procedures.Last reviewed on RxList: 10/3/2007





Other reviews about Ceftriaxone on wordpress

Identification and characterization of ceftriaxone resistance and extended-spectrum ß-lactamases in Malawian bacteraemic Enterobacteriaceae
  by JOC
Source: Journal of Antimicrobial Chemotherapy Apr 2006 vol.57 n.4 p.661-665 Katherine J. Gray1,2,*, Lorna K. Wilson1, Amos Phiri1, John E. Corkill2, Neil French1,3 and C. Anthony Hart2 1 Malawi-Liverpool-Wellcome […]


Random Thoughts from Day #2
  by tfernan0
1.) Sorry KBA, no "mother's milk" (vanco/zosyn) here. Empiric antibiotic of choice is Ceftriaxone alone. 2.) India has a pay-for-performance health care system. The patients pay upfront and then […]


More musings from Pondi....
  by parask
As per the usual, Brian did an excellent job in covering what happened on the Pediatrics side of things here in Pondi. One comment from that... I am […]


Waterhouse Friderichsen Syndrome
  by Rahil
A meningitis associated septicemia that produces hemorrhagic infarction of the adrenal gland and cutaneous petechiae, often seen in a setting post-meningococcal and pneumococcal meningitis. This condition is life threatening […]


Back To Kindergarten
  by Jojo
Back home early today.. Not feeling very well.. Feeling absolutely pissed at the head nurse at D4.. She made me feel like I was back at kindergarten.. During our […]


Abstract
  by ctxm
    Resistance to antimicrobial agents is commonly found in Enterobacteriaceae which is common pathogens isolated from clinical specimen. The most common mechanism of third generation cephalosporin resistance in Enterobacteriaceae […]


Pilot Study of Ampicillin-Ceftriaxone Combination for Treatment of Orthopedic Infections Due to Enterococcus faecalis
  by JOC
Antimicrobial Agents and Chemotherapy  1 Oct 2009  V.53  N.10  p.4305-4310 G. Euba,1* J. Lora-Tamayo,1 O. Murillo,1 S. Pedrero,2 J. Cabo,2 R. Verdaguer,3 and J. Ariza1 Infectious Diseases Department,1 […]


Jawapan Clinical Quiz/4
  by drcd2009
Q1: CONDITION and COMPLICATION • Appearance – pale, mottled, lethargic • Airway – intact and not at risk of aspiration • Breathing – RR is appropriate for his age • Circulation – HR is at the […]


DEATHS IN NEWBORNS ASSOCIATED WITH USE OF ceftriaxone (rocephin)
  by KIRBY JOHNSON, PC
The FDA has received seven case reports of serious cardiopulmonary adverse events in neonates associated with precipitation of a ceftriaxone-calcium salt in the lung and/or kidneys.  Six neonates […]


Ambulatory Care - Ondansetron, Febrile neutropenia
  by haleygill
I have 2 new autologous stem cell transplant patients this week. 1 was transplanted yesterday and 1 today. I did medication reviews, medication counseling and med calendars for […]



Other reviews about Ceftriaxone on web:

Ceftriaxone (pronounced /ˌsɛftraɪˈæksoʊn/) is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against ... Ceftriaxone - Wikipedia, the free encyclopedia


Provides information on usage, precautions, side effects and brand names when available. Data provided by various government agencies and health-related organizations. Ceftriaxone Injection: MedlinePlus Drug Information


Accurate, FDA approved Ceftriaxone information for healthcare professionals and patients - brought to you by Drugs.com. Ceftriaxone Official FDA information, side effects and uses.


ceftriaxone ( ) n. A semisynthetic analogue of cephalosporin, C 18 H 16 N 8 Na 2 O 7 S 3 , that is administered parenterally and has a broad spectrum ceftriaxone: Definition from Answers.com


All about Ceftriaxone. View complete and up to date Ceftriaxone information - part of the Drugs.com trusted medication database. Ceftriaxone Facts and Comparisons at Drugs.com


Learn about the prescription medication Ceftriaxone (Ceftriaxone Sodium and Dextrose Injection), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient ... Ceftriaxone (Ceftriaxone Sodium and Dextrose Injection) Drug ...


Learn about the prescription medication Rocephin (Ceftriaxone), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Rocephin (Ceftriaxone) Drug Information: Uses, Side Effects, Drug ...


Ceftriaxone is a prescription antibiotic that is used to stop and prevent infections. This page from the eMedTV archives offers an overview of ceftriaxone and explains how it ... Ceftriaxone


Find patient medical information for Ceftriaxone Inj on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Ceftriaxone Inj : Uses, Side Effects, Interactions, Pictures ...


ceftriaxone /cef·tri·ax·one/ (cef″tri-ak´sōn) a semisynthetic, β –resistant, third-generation cephalosporin effective against a wide range of gram-positive and gram ... ceftriaxone - definition of ceftriaxone in the Medical dictionary ...





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