Reviews Busulfex


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Busulfex Drug Description
BUSULFEX®
(busulfan) Injection
Caution: Must be diluted prior to use.

WARNING
BUSULFEX® (busulfan) Injection is a potent cytotoxic drug that causes profound
myelosuppression at the recommended dosage. It should be administered under
the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic
drugs and the managementof patients with severe pancytopenia. Appropriate
management of therapy and complications is only possible when adequate diagnostic
and treatment facilities are readily available. SEE "WARNINGS"
SECTION FOR INFORMATION REGARDING BUSULFAN-INDUCED PANCYTOPENIA IN HUMANS.

DRUG DESCRIPTION



What are the possible side effects of busulfan (Busulfex, Myleran)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
unusual bleeding or bruising;
fever or chills;
sudden weakness or unusual fatigue;
persistent cough, congestion, or shortness of breath;
flank, stomach or joint...
Read All Potential Side Effects for Busulfex »




Busulfan is a bifunctional alkylating agent known chemically as 1,4- butanediol,
dimethanesulfonate. BUSULFEX® (busulfan) Injection is intended for intravenous
administration. It is supplied as a clear, colorless, sterile, solution in 10
mL single use vials. Each vial of BUSULFEX contains 60 mg (6 mg/mL) of busulfan,
the active ingredient, a white crystalline powder with a molecular formula of
CH3SO2O(CH2)4OSO2CH3
and a molecular weight of 246 g/mole. Busulfan is dissolved in N,N-dimethylacetamide
(DMA) 33% vol/vol and Polyethylene Glycol 400, 67% vol/vol. The solubility of
busulfan in water is 0.1 g/L and the pH of BUSULFEX diluted to approximately
0.5 mg/mL busulfan in 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection,
USP as recommended for infusion reflects the pH of the diluent used and ranges
from 3.4 to 3.9.
BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP prior to intravenous infusion.
Last reviewed on RxList: 1/10/2008




Busulfex Drug Description
BUSULFEX®
(busulfan) Injection
Caution: Must be diluted prior to use.

WARNING
BUSULFEX® (busulfan) Injection is a potent cytotoxic drug that causes profound
myelosuppression at the recommended dosage. It should be administered under
the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic
drugs and the managementof patients with severe pancytopenia. Appropriate
management of therapy and complications is only possible when adequate diagnostic
and treatment facilities are readily available. SEE "WARNINGS"
SECTION FOR INFORMATION REGARDING BUSULFAN-INDUCED PANCYTOPENIA IN HUMANS.

DRUG DESCRIPTION



What are the possible side effects of busulfan (Busulfex, Myleran)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
unusual bleeding or bruising;
fever or chills;
sudden weakness or unusual fatigue;
persistent cough, congestion, or shortness of breath;
flank, stomach or joint...
Read All Potential Side Effects for Busulfex »




Busulfan is a bifunctional alkylating agent known chemically as 1,4- butanediol,
dimethanesulfonate. BUSULFEX® (busulfan) Injection is intended for intravenous
administration. It is supplied as a clear, colorless, sterile, solution in 10
mL single use vials. Each vial of BUSULFEX contains 60 mg (6 mg/mL) of busulfan,
the active ingredient, a white crystalline powder with a molecular formula of
CH3SO2O(CH2)4OSO2CH3
and a molecular weight of 246 g/mole. Busulfan is dissolved in N,N-dimethylacetamide
(DMA) 33% vol/vol and Polyethylene Glycol 400, 67% vol/vol. The solubility of
busulfan in water is 0.1 g/L and the pH of BUSULFEX diluted to approximately
0.5 mg/mL busulfan in 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection,
USP as recommended for infusion reflects the pH of the diluent used and ranges
from 3.4 to 3.9.
BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP prior to intravenous infusion.
Last reviewed on RxList: 1/10/2008




Busulfex Drug Description
BUSULFEX®
(busulfan) Injection
Caution: Must be diluted prior to use.

WARNING
BUSULFEX® (busulfan) Injection is a potent cytotoxic drug that causes profound
myelosuppression at the recommended dosage. It should be administered under
the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic
drugs and the managementof patients with severe pancytopenia. Appropriate
management of therapy and complications is only possible when adequate diagnostic
and treatment facilities are readily available. SEE "WARNINGS"
SECTION FOR INFORMATION REGARDING BUSULFAN-INDUCED PANCYTOPENIA IN HUMANS.

DRUG DESCRIPTION



What are the possible side effects of busulfan (Busulfex, Myleran)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
unusual bleeding or bruising;
fever or chills;
sudden weakness or unusual fatigue;
persistent cough, congestion, or shortness of breath;
flank, stomach or joint...
Read All Potential Side Effects for Busulfex »




Busulfan is a bifunctional alkylating agent known chemically as 1,4- butanediol,
dimethanesulfonate. BUSULFEX® (busulfan) Injection is intended for intravenous
administration. It is supplied as a clear, colorless, sterile, solution in 10
mL single use vials. Each vial of BUSULFEX contains 60 mg (6 mg/mL) of busulfan,
the active ingredient, a white crystalline powder with a molecular formula of
CH3SO2O(CH2)4OSO2CH3
and a molecular weight of 246 g/mole. Busulfan is dissolved in N,N-dimethylacetamide
(DMA) 33% vol/vol and Polyethylene Glycol 400, 67% vol/vol. The solubility of
busulfan in water is 0.1 g/L and the pH of BUSULFEX diluted to approximately
0.5 mg/mL busulfan in 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection,
USP as recommended for infusion reflects the pH of the diluent used and ranges
from 3.4 to 3.9.
BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP prior to intravenous infusion.
Last reviewed on RxList: 1/10/2008




Busulfex Drug Description
BUSULFEX®
(busulfan) Injection
Caution: Must be diluted prior to use.

WARNING
BUSULFEX® (busulfan) Injection is a potent cytotoxic drug that causes profound
myelosuppression at the recommended dosage. It should be administered under
the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic
drugs and the managementof patients with severe pancytopenia. Appropriate
management of therapy and complications is only possible when adequate diagnostic
and treatment facilities are readily available. SEE "WARNINGS"
SECTION FOR INFORMATION REGARDING BUSULFAN-INDUCED PANCYTOPENIA IN HUMANS.

DRUG DESCRIPTION



What are the possible side effects of busulfan (Busulfex, Myleran)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
unusual bleeding or bruising;
fever or chills;
sudden weakness or unusual fatigue;
persistent cough, congestion, or shortness of breath;
flank, stomach or joint...
Read All Potential Side Effects for Busulfex »




Busulfan is a bifunctional alkylating agent known chemically as 1,4- butanediol,
dimethanesulfonate. BUSULFEX® (busulfan) Injection is intended for intravenous
administration. It is supplied as a clear, colorless, sterile, solution in 10
mL single use vials. Each vial of BUSULFEX contains 60 mg (6 mg/mL) of busulfan,
the active ingredient, a white crystalline powder with a molecular formula of
CH3SO2O(CH2)4OSO2CH3
and a molecular weight of 246 g/mole. Busulfan is dissolved in N,N-dimethylacetamide
(DMA) 33% vol/vol and Polyethylene Glycol 400, 67% vol/vol. The solubility of
busulfan in water is 0.1 g/L and the pH of BUSULFEX diluted to approximately
0.5 mg/mL busulfan in 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection,
USP as recommended for infusion reflects the pH of the diluent used and ranges
from 3.4 to 3.9.
BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP prior to intravenous infusion.
Last reviewed on RxList: 1/10/2008




Busulfex Drug Description
BUSULFEX®
(busulfan) Injection
Caution: Must be diluted prior to use.

WARNING
BUSULFEX® (busulfan) Injection is a potent cytotoxic drug that causes profound
myelosuppression at the recommended dosage. It should be administered under
the supervision of a qualified physician who is experienced in allogeneic hematopoietic stem cell transplantation, the use of cancer chemotherapeutic
drugs and the managementof patients with severe pancytopenia. Appropriate
management of therapy and complications is only possible when adequate diagnostic
and treatment facilities are readily available. SEE "WARNINGS"
SECTION FOR INFORMATION REGARDING BUSULFAN-INDUCED PANCYTOPENIA IN HUMANS.

DRUG DESCRIPTION



What are the possible side effects of busulfan (Busulfex, Myleran)?

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

an allergic reaction (shortness of breath; closing of the throat; difficulty breathing; swelling of your lips, face, or tongue; or hives);
unusual bleeding or bruising;
fever or chills;
sudden weakness or unusual fatigue;
persistent cough, congestion, or shortness of breath;
flank, stomach or joint...
Read All Potential Side Effects for Busulfex »




Busulfan is a bifunctional alkylating agent known chemically as 1,4- butanediol,
dimethanesulfonate. BUSULFEX® (busulfan) Injection is intended for intravenous
administration. It is supplied as a clear, colorless, sterile, solution in 10
mL single use vials. Each vial of BUSULFEX contains 60 mg (6 mg/mL) of busulfan,
the active ingredient, a white crystalline powder with a molecular formula of
CH3SO2O(CH2)4OSO2CH3
and a molecular weight of 246 g/mole. Busulfan is dissolved in N,N-dimethylacetamide
(DMA) 33% vol/vol and Polyethylene Glycol 400, 67% vol/vol. The solubility of
busulfan in water is 0.1 g/L and the pH of BUSULFEX diluted to approximately
0.5 mg/mL busulfan in 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection,
USP as recommended for infusion reflects the pH of the diluent used and ranges
from 3.4 to 3.9.
BUSULFEX is intended for dilution with 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP prior to intravenous infusion.
Last reviewed on RxList: 1/10/2008





Other reviews about Busulfex on web:

Predictable pharmacokinetics 93% of patients (55/59) maintained AUC values below the target value † with no dose adjustments 1; 100% engraftment IV BUSULFEX (busulfan) Injection


Learn about the prescription medication Busulfex (Busulfan), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Busulfex (Busulfan) Drug Information: Uses, Side Effects, Drug ...


All about Busulfex. View complete and up to date Busulfex information - part of the Drugs.com trusted medication database. Busulfex Facts and Comparisons at Drugs.com


Accurate, FDA approved Busulfex information for healthcare professionals and patients - brought to you by Drugs.com. Busulfex Official FDA information, side effects and uses.


Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, PDL BioPharma, Inc.) is a cancer drug, in use since 1959. Busulfan is a cell cycle non-specific alkylating antineoplastic agent, in ... Busulfan - Wikipedia, the free encyclopedia


BUSULFEX This page contains recent news articles, when available, and an overview of BUSULFEX but does not offer medical advice. You should contact your physician with regard to any ... BUSULFEX


Find patient medical information for Busulfex IV on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Busulfex IV : Uses, Side Effects, Interactions, Pictures, Warnings ...


Busulfex is the trade name for Busulfan. Myleran is another trade name for Busulfan. Busulfex is an anti-cancer chemotherapy drug classified as an alkylating agent. Busulfex, Busulfan, Myleran - Chemotherapy Drugs, Chemo Drug Side ...


Busulfan is an antineoplastic in the class of alkylating agents and is used to treat various forms o... Busulfex - Antineoplastic Agents, Immunosuppressive Agents ...


Initial Dose Calculation. 0.8 mg/kg of ideal body weight or actual body weight, whichever is lower; Administered via central venous catheter as a 2-hour infusion on the baseis of every ... IV BUSULFEX (busulfan) Injection





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