Reviews Bupropion Hydrobromide Tablet


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Aplenzin Drug Description
Aplenzin
(bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use

SUICIDALITY AND ANTIDEPRESSANT DRUGS
Antidepressants increased the risk compared to placebo of suicidal thinking
and behavior
(suicidality) in children, adolescents, and young adults in short-term studies
of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering
the use of Aplenzin™ or any other antidepressant in a child, adolescent, or
young adult must balance this risk with the clinical need. Short-term studies
did not show an increase in the risk of suicidality with antidepressants compared
to placebo in adults beyond age 24; there was a reduction in risk with antidepressants
compared to placebo in adults aged 65 and older. Depression and certain other
psychiatric disorders are themselves associated with increases in the risk of
suicide.
Patients of all ages who are started on antidepressant therapy should be monitored
appropriately and observed closely for clinical worsening, suicidality, or unusual
changes in behavior. Families and caregivers should be advised of the need for
close observation and communication with the prescriber. Aplenzin is not approved
for use in pediatric patients. [See WARNINGS AND PRECAUTIONS: Clinical Worsening
and Suicide Risk and Use In Specific Populations: Pediatric Use]

DRUG DESCRIPTION
Aplenzin (bupropion hydrobromide), an antidepressant of the aminoketone class,
is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely resembles
that of diethylpropion; it is related to phenylethylamines. It is designated
as (±)-2-(tert-butylamino)-3'-chloropropiophenone hydrobromide. The molecular
weight is 320.6. The molecular formula is C13H18ClNO•HBr.
Bupropion hydrobromide powder is white or almost white, crystalline, and soluble
in water. It has a bitter taste and produces the sensation of local anesthesia
on the oral mucosa. The structural formula is:








Aplenzin Tablets are supplied for oral administration as 174 mg, 348 mg, and
522 mg white to off white extended-release tablets. Each tablet contains the
labeled amount of bupropion hydrobromide and the inactive ingredients: ethylcellulose
aqueous dispersion, glyceryl behenate, polyvinyl alcohol, polyethylene glycol,
povidone, and dibutyl sebacate. Carnauba wax is included in the 174 mg and 348
mg strengths. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during
gastrointestinal transit and is eliminated in the feces.Last reviewed on RxList: 5/20/2010




Aplenzin Drug Description
Aplenzin
(bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use

SUICIDALITY AND ANTIDEPRESSANT DRUGS
Antidepressants increased the risk compared to placebo of suicidal thinking
and behavior
(suicidality) in children, adolescents, and young adults in short-term studies
of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering
the use of Aplenzin™ or any other antidepressant in a child, adolescent, or
young adult must balance this risk with the clinical need. Short-term studies
did not show an increase in the risk of suicidality with antidepressants compared
to placebo in adults beyond age 24; there was a reduction in risk with antidepressants
compared to placebo in adults aged 65 and older. Depression and certain other
psychiatric disorders are themselves associated with increases in the risk of
suicide.
Patients of all ages who are started on antidepressant therapy should be monitored
appropriately and observed closely for clinical worsening, suicidality, or unusual
changes in behavior. Families and caregivers should be advised of the need for
close observation and communication with the prescriber. Aplenzin is not approved
for use in pediatric patients. [See WARNINGS AND PRECAUTIONS: Clinical Worsening
and Suicide Risk and Use In Specific Populations: Pediatric Use]

DRUG DESCRIPTION
Aplenzin (bupropion hydrobromide), an antidepressant of the aminoketone class,
is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely resembles
that of diethylpropion; it is related to phenylethylamines. It is designated
as (±)-2-(tert-butylamino)-3'-chloropropiophenone hydrobromide. The molecular
weight is 320.6. The molecular formula is C13H18ClNO•HBr.
Bupropion hydrobromide powder is white or almost white, crystalline, and soluble
in water. It has a bitter taste and produces the sensation of local anesthesia
on the oral mucosa. The structural formula is:








Aplenzin Tablets are supplied for oral administration as 174 mg, 348 mg, and
522 mg white to off white extended-release tablets. Each tablet contains the
labeled amount of bupropion hydrobromide and the inactive ingredients: ethylcellulose
aqueous dispersion, glyceryl behenate, polyvinyl alcohol, polyethylene glycol,
povidone, and dibutyl sebacate. Carnauba wax is included in the 174 mg and 348
mg strengths. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during
gastrointestinal transit and is eliminated in the feces.Last reviewed on RxList: 5/20/2010




Aplenzin Drug Description
Aplenzin
(bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use

SUICIDALITY AND ANTIDEPRESSANT DRUGS
Antidepressants increased the risk compared to placebo of suicidal thinking
and behavior
(suicidality) in children, adolescents, and young adults in short-term studies
of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering
the use of Aplenzin™ or any other antidepressant in a child, adolescent, or
young adult must balance this risk with the clinical need. Short-term studies
did not show an increase in the risk of suicidality with antidepressants compared
to placebo in adults beyond age 24; there was a reduction in risk with antidepressants
compared to placebo in adults aged 65 and older. Depression and certain other
psychiatric disorders are themselves associated with increases in the risk of
suicide.
Patients of all ages who are started on antidepressant therapy should be monitored
appropriately and observed closely for clinical worsening, suicidality, or unusual
changes in behavior. Families and caregivers should be advised of the need for
close observation and communication with the prescriber. Aplenzin is not approved
for use in pediatric patients. [See WARNINGS AND PRECAUTIONS: Clinical Worsening
and Suicide Risk and Use In Specific Populations: Pediatric Use]

DRUG DESCRIPTION
Aplenzin (bupropion hydrobromide), an antidepressant of the aminoketone class,
is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely resembles
that of diethylpropion; it is related to phenylethylamines. It is designated
as (±)-2-(tert-butylamino)-3'-chloropropiophenone hydrobromide. The molecular
weight is 320.6. The molecular formula is C13H18ClNO•HBr.
Bupropion hydrobromide powder is white or almost white, crystalline, and soluble
in water. It has a bitter taste and produces the sensation of local anesthesia
on the oral mucosa. The structural formula is:








Aplenzin Tablets are supplied for oral administration as 174 mg, 348 mg, and
522 mg white to off white extended-release tablets. Each tablet contains the
labeled amount of bupropion hydrobromide and the inactive ingredients: ethylcellulose
aqueous dispersion, glyceryl behenate, polyvinyl alcohol, polyethylene glycol,
povidone, and dibutyl sebacate. Carnauba wax is included in the 174 mg and 348
mg strengths. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during
gastrointestinal transit and is eliminated in the feces.Last reviewed on RxList: 5/20/2010




Aplenzin Drug Description
Aplenzin
(bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use

SUICIDALITY AND ANTIDEPRESSANT DRUGS
Antidepressants increased the risk compared to placebo of suicidal thinking
and behavior
(suicidality) in children, adolescents, and young adults in short-term studies
of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering
the use of Aplenzin™ or any other antidepressant in a child, adolescent, or
young adult must balance this risk with the clinical need. Short-term studies
did not show an increase in the risk of suicidality with antidepressants compared
to placebo in adults beyond age 24; there was a reduction in risk with antidepressants
compared to placebo in adults aged 65 and older. Depression and certain other
psychiatric disorders are themselves associated with increases in the risk of
suicide.
Patients of all ages who are started on antidepressant therapy should be monitored
appropriately and observed closely for clinical worsening, suicidality, or unusual
changes in behavior. Families and caregivers should be advised of the need for
close observation and communication with the prescriber. Aplenzin is not approved
for use in pediatric patients. [See WARNINGS AND PRECAUTIONS: Clinical Worsening
and Suicide Risk and Use In Specific Populations: Pediatric Use]

DRUG DESCRIPTION
Aplenzin (bupropion hydrobromide), an antidepressant of the aminoketone class,
is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely resembles
that of diethylpropion; it is related to phenylethylamines. It is designated
as (±)-2-(tert-butylamino)-3'-chloropropiophenone hydrobromide. The molecular
weight is 320.6. The molecular formula is C13H18ClNO•HBr.
Bupropion hydrobromide powder is white or almost white, crystalline, and soluble
in water. It has a bitter taste and produces the sensation of local anesthesia
on the oral mucosa. The structural formula is:








Aplenzin Tablets are supplied for oral administration as 174 mg, 348 mg, and
522 mg white to off white extended-release tablets. Each tablet contains the
labeled amount of bupropion hydrobromide and the inactive ingredients: ethylcellulose
aqueous dispersion, glyceryl behenate, polyvinyl alcohol, polyethylene glycol,
povidone, and dibutyl sebacate. Carnauba wax is included in the 174 mg and 348
mg strengths. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during
gastrointestinal transit and is eliminated in the feces.Last reviewed on RxList: 5/20/2010




Aplenzin Drug Description
Aplenzin
(bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use

SUICIDALITY AND ANTIDEPRESSANT DRUGS
Antidepressants increased the risk compared to placebo of suicidal thinking
and behavior
(suicidality) in children, adolescents, and young adults in short-term studies
of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering
the use of Aplenzin™ or any other antidepressant in a child, adolescent, or
young adult must balance this risk with the clinical need. Short-term studies
did not show an increase in the risk of suicidality with antidepressants compared
to placebo in adults beyond age 24; there was a reduction in risk with antidepressants
compared to placebo in adults aged 65 and older. Depression and certain other
psychiatric disorders are themselves associated with increases in the risk of
suicide.
Patients of all ages who are started on antidepressant therapy should be monitored
appropriately and observed closely for clinical worsening, suicidality, or unusual
changes in behavior. Families and caregivers should be advised of the need for
close observation and communication with the prescriber. Aplenzin is not approved
for use in pediatric patients. [See WARNINGS AND PRECAUTIONS: Clinical Worsening
and Suicide Risk and Use In Specific Populations: Pediatric Use]

DRUG DESCRIPTION
Aplenzin (bupropion hydrobromide), an antidepressant of the aminoketone class,
is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely resembles
that of diethylpropion; it is related to phenylethylamines. It is designated
as (±)-2-(tert-butylamino)-3'-chloropropiophenone hydrobromide. The molecular
weight is 320.6. The molecular formula is C13H18ClNO•HBr.
Bupropion hydrobromide powder is white or almost white, crystalline, and soluble
in water. It has a bitter taste and produces the sensation of local anesthesia
on the oral mucosa. The structural formula is:








Aplenzin Tablets are supplied for oral administration as 174 mg, 348 mg, and
522 mg white to off white extended-release tablets. Each tablet contains the
labeled amount of bupropion hydrobromide and the inactive ingredients: ethylcellulose
aqueous dispersion, glyceryl behenate, polyvinyl alcohol, polyethylene glycol,
povidone, and dibutyl sebacate. Carnauba wax is included in the 174 mg and 348
mg strengths. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during
gastrointestinal transit and is eliminated in the feces.Last reviewed on RxList: 5/20/2010





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Other reviews about Bupropion Hydrobromide Tablet on web:

All about Bupropion Hydrobromide Extended-Release Tablets. View complete and up to date Bupropion Hydrobromide information - part of the Drugs.com trusted medication database. Bupropion Hydrobromide Extended-Release Tablets Facts and ...


Bupropion Hydrobromide Oral tablet, extended-release To return to the main entry click here . What is this medicine? BUPROPION (byoo PROE pee on) is Bupropion Hydrobromide Oral tablet, extended-release: Information ...


Bupropion Hydrobromide Oral tablet, extended-release What is this medicine? BUPROPION (byoo PROE pee on) is used to treat depression. This medicine may be used for other purposes; ask ... Bupropion


Bupropion Pronunciation: (bue-PROE-pee-on) Class: Antidepressant, Smoking deterrent Trade Names: Aplenzin - Tablets, ER 174 mg as hydrobromide - Tablets, ER 348 mg as hydrobromide Complete Bupropion Hydrochloride information from Drugs.com


Aplenzin (bupropion hydrobromide) Tablet, Film Coated, Extended Release for Oral use Initial U.S. Approval: 1985 WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS See full prescribing ... Aplenzin bupropion hydrobromide


Bupropion Hydrobromide Oral tablet, extended-release Bupropion


Bupropion Hydrobromide Oral tablet, extended-release What is this medicine? BUPROPION (byoo PROE pee on) is used to treat depression. This medicine may be used for other purposes; ask ... Memorial Health Care System: Drug Reference


Learn about the prescription medication Aplenzin (Bupropion Hydrobromide Tablet), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Aplenzin (Bupropion Hydrobromide Tablet) Drug Information: Uses ...


Patent Claims: We claim: 1. A modified release bupropion hydrobromide tablet suitable for oral administration having enhanced stability comprising: (a) a core comprising (i) a ... Modified release formulations of a bupropion salt - US Patent ...


Show Comments that relate to all doses of APLENZIN Show Comments that are specific to APLENZIN TABLET, EXTENDED RELEASE Show Comments for all medications containing BUPROPION ... MEDSort - APLENZIN TABLET, EXTENDED RELEASE(BUPROPION HYDROBROMIDE ...





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