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Brevibloc Drug Description
BREVIBLOC PREMIXED INJECTION
(esmolol hydrochloride)
2,500 mg/250 mL (10 mg/mL) Ready-to-use Bags
250 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH PREMIXED INJECTION
(esmolol hydrochloride)
2,000 mg/100 mL (20 mg/mL) Ready-to-use Bags
100 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC INJECTION
(esmolol hydrochloride)
100 mg/10 mL (10 mg/mL) Ready-to-use Vials
10 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH INJECTION
(esmolol hydrochloride)
100 mg/5 mL (20 mg/mL) Ready-to-use Vials
5 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
DRUG DESCRIPTION



What are the possible side effects of esmolol (Brevibloc)?

Esmolol use has been associated with low blood pressure and other serious side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
Read All Potential Side Effects for Brevibloc »




BREVIBLOC (Esmolol Hydrochloride) is a beta1-selective (cardioselective)
adrenergic receptor blocking agent with a very short duration of action (elimination
half-life is approximately 9 minutes). Esmolol Hydrochloride is:
(±)-Methyl p-[2-hydroxy-3-(isopropylamino) propoxy] hydrocinnamate hydrochloride
and has the following structure:







Esmolol Hydrochloride has the empirical formula C16H26NO4Cl
and a molecular weight of 331.8. It has one asymmetric center and exists as
an enantiomeric pair.
Esmolol Hydrochloride is a white to off-white crystalline powder. It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. Its partition coefficient (octanol/water) at pH 7.0 is 0.42 compared to 17.0 for propranolol.
Brevibloc Premixed Injection
BREVIBLOC PREMIXED INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
2500 mg, 250 mL Single Use Premixed Bag - Each mL contains 10 mg Esmolol
Hydrochloride, 5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered
with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid,
USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary, to adjust
pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The 250 mL bag
is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia bag is
manufactured from a specially designed multilayer plastic (PL 2408). Solutions
in contact with the plastic container leach out certain chemical compounds from
the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
2000 mg, 100 mL Single Use Premixed Bag DOUBLE STRENGTH - Each mL contains
20 mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary,
to adjust pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The
100 mL bag is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia
bag is manufactured from a specially designed multilayer plastic (PL 2408).
Solutions in contact with the plastic container leach out certain chemical compounds
from the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
Brevibloc Injection
BREVIBLOC INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
100 mg, 10 mL Single Dose Vial - Each mL contains 10 mg Esmolol Hydrochloride,
5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered with 2.8
mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid, USP. Sodium
Hydroxide and/or Hydrochloric Acid added, as necessary to adjust pH to 5.0 (4.5-5.5).
100 mg, 5 mL DOUBLE STRENGTH Single Dose Vial - Each mL contains 20
mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary
to adjust pH to 5.0 (4.5-5.5).Last reviewed on RxList: 12/3/2007




Brevibloc Drug Description
BREVIBLOC PREMIXED INJECTION
(esmolol hydrochloride)
2,500 mg/250 mL (10 mg/mL) Ready-to-use Bags
250 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH PREMIXED INJECTION
(esmolol hydrochloride)
2,000 mg/100 mL (20 mg/mL) Ready-to-use Bags
100 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC INJECTION
(esmolol hydrochloride)
100 mg/10 mL (10 mg/mL) Ready-to-use Vials
10 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH INJECTION
(esmolol hydrochloride)
100 mg/5 mL (20 mg/mL) Ready-to-use Vials
5 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
DRUG DESCRIPTION



What are the possible side effects of esmolol (Brevibloc)?

Esmolol use has been associated with low blood pressure and other serious side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
Read All Potential Side Effects for Brevibloc »




BREVIBLOC (Esmolol Hydrochloride) is a beta1-selective (cardioselective)
adrenergic receptor blocking agent with a very short duration of action (elimination
half-life is approximately 9 minutes). Esmolol Hydrochloride is:
(±)-Methyl p-[2-hydroxy-3-(isopropylamino) propoxy] hydrocinnamate hydrochloride
and has the following structure:







Esmolol Hydrochloride has the empirical formula C16H26NO4Cl
and a molecular weight of 331.8. It has one asymmetric center and exists as
an enantiomeric pair.
Esmolol Hydrochloride is a white to off-white crystalline powder. It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. Its partition coefficient (octanol/water) at pH 7.0 is 0.42 compared to 17.0 for propranolol.
Brevibloc Premixed Injection
BREVIBLOC PREMIXED INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
2500 mg, 250 mL Single Use Premixed Bag - Each mL contains 10 mg Esmolol
Hydrochloride, 5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered
with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid,
USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary, to adjust
pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The 250 mL bag
is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia bag is
manufactured from a specially designed multilayer plastic (PL 2408). Solutions
in contact with the plastic container leach out certain chemical compounds from
the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
2000 mg, 100 mL Single Use Premixed Bag DOUBLE STRENGTH - Each mL contains
20 mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary,
to adjust pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The
100 mL bag is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia
bag is manufactured from a specially designed multilayer plastic (PL 2408).
Solutions in contact with the plastic container leach out certain chemical compounds
from the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
Brevibloc Injection
BREVIBLOC INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
100 mg, 10 mL Single Dose Vial - Each mL contains 10 mg Esmolol Hydrochloride,
5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered with 2.8
mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid, USP. Sodium
Hydroxide and/or Hydrochloric Acid added, as necessary to adjust pH to 5.0 (4.5-5.5).
100 mg, 5 mL DOUBLE STRENGTH Single Dose Vial - Each mL contains 20
mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary
to adjust pH to 5.0 (4.5-5.5).Last reviewed on RxList: 12/3/2007




Brevibloc Drug Description
BREVIBLOC PREMIXED INJECTION
(esmolol hydrochloride)
2,500 mg/250 mL (10 mg/mL) Ready-to-use Bags
250 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH PREMIXED INJECTION
(esmolol hydrochloride)
2,000 mg/100 mL (20 mg/mL) Ready-to-use Bags
100 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC INJECTION
(esmolol hydrochloride)
100 mg/10 mL (10 mg/mL) Ready-to-use Vials
10 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH INJECTION
(esmolol hydrochloride)
100 mg/5 mL (20 mg/mL) Ready-to-use Vials
5 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
DRUG DESCRIPTION



What are the possible side effects of esmolol (Brevibloc)?

Esmolol use has been associated with low blood pressure and other serious side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
Read All Potential Side Effects for Brevibloc »




BREVIBLOC (Esmolol Hydrochloride) is a beta1-selective (cardioselective)
adrenergic receptor blocking agent with a very short duration of action (elimination
half-life is approximately 9 minutes). Esmolol Hydrochloride is:
(±)-Methyl p-[2-hydroxy-3-(isopropylamino) propoxy] hydrocinnamate hydrochloride
and has the following structure:







Esmolol Hydrochloride has the empirical formula C16H26NO4Cl
and a molecular weight of 331.8. It has one asymmetric center and exists as
an enantiomeric pair.
Esmolol Hydrochloride is a white to off-white crystalline powder. It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. Its partition coefficient (octanol/water) at pH 7.0 is 0.42 compared to 17.0 for propranolol.
Brevibloc Premixed Injection
BREVIBLOC PREMIXED INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
2500 mg, 250 mL Single Use Premixed Bag - Each mL contains 10 mg Esmolol
Hydrochloride, 5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered
with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid,
USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary, to adjust
pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The 250 mL bag
is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia bag is
manufactured from a specially designed multilayer plastic (PL 2408). Solutions
in contact with the plastic container leach out certain chemical compounds from
the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
2000 mg, 100 mL Single Use Premixed Bag DOUBLE STRENGTH - Each mL contains
20 mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary,
to adjust pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The
100 mL bag is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia
bag is manufactured from a specially designed multilayer plastic (PL 2408).
Solutions in contact with the plastic container leach out certain chemical compounds
from the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
Brevibloc Injection
BREVIBLOC INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
100 mg, 10 mL Single Dose Vial - Each mL contains 10 mg Esmolol Hydrochloride,
5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered with 2.8
mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid, USP. Sodium
Hydroxide and/or Hydrochloric Acid added, as necessary to adjust pH to 5.0 (4.5-5.5).
100 mg, 5 mL DOUBLE STRENGTH Single Dose Vial - Each mL contains 20
mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary
to adjust pH to 5.0 (4.5-5.5).Last reviewed on RxList: 12/3/2007




Brevibloc Drug Description
BREVIBLOC PREMIXED INJECTION
(esmolol hydrochloride)
2,500 mg/250 mL (10 mg/mL) Ready-to-use Bags
250 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH PREMIXED INJECTION
(esmolol hydrochloride)
2,000 mg/100 mL (20 mg/mL) Ready-to-use Bags
100 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC INJECTION
(esmolol hydrochloride)
100 mg/10 mL (10 mg/mL) Ready-to-use Vials
10 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH INJECTION
(esmolol hydrochloride)
100 mg/5 mL (20 mg/mL) Ready-to-use Vials
5 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
DRUG DESCRIPTION



What are the possible side effects of esmolol (Brevibloc)?

Esmolol use has been associated with low blood pressure and other serious side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
Read All Potential Side Effects for Brevibloc »




BREVIBLOC (Esmolol Hydrochloride) is a beta1-selective (cardioselective)
adrenergic receptor blocking agent with a very short duration of action (elimination
half-life is approximately 9 minutes). Esmolol Hydrochloride is:
(±)-Methyl p-[2-hydroxy-3-(isopropylamino) propoxy] hydrocinnamate hydrochloride
and has the following structure:







Esmolol Hydrochloride has the empirical formula C16H26NO4Cl
and a molecular weight of 331.8. It has one asymmetric center and exists as
an enantiomeric pair.
Esmolol Hydrochloride is a white to off-white crystalline powder. It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. Its partition coefficient (octanol/water) at pH 7.0 is 0.42 compared to 17.0 for propranolol.
Brevibloc Premixed Injection
BREVIBLOC PREMIXED INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
2500 mg, 250 mL Single Use Premixed Bag - Each mL contains 10 mg Esmolol
Hydrochloride, 5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered
with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid,
USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary, to adjust
pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The 250 mL bag
is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia bag is
manufactured from a specially designed multilayer plastic (PL 2408). Solutions
in contact with the plastic container leach out certain chemical compounds from
the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
2000 mg, 100 mL Single Use Premixed Bag DOUBLE STRENGTH - Each mL contains
20 mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary,
to adjust pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The
100 mL bag is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia
bag is manufactured from a specially designed multilayer plastic (PL 2408).
Solutions in contact with the plastic container leach out certain chemical compounds
from the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
Brevibloc Injection
BREVIBLOC INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
100 mg, 10 mL Single Dose Vial - Each mL contains 10 mg Esmolol Hydrochloride,
5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered with 2.8
mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid, USP. Sodium
Hydroxide and/or Hydrochloric Acid added, as necessary to adjust pH to 5.0 (4.5-5.5).
100 mg, 5 mL DOUBLE STRENGTH Single Dose Vial - Each mL contains 20
mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary
to adjust pH to 5.0 (4.5-5.5).Last reviewed on RxList: 12/3/2007




Brevibloc Drug Description
BREVIBLOC PREMIXED INJECTION
(esmolol hydrochloride)
2,500 mg/250 mL (10 mg/mL) Ready-to-use Bags
250 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH PREMIXED INJECTION
(esmolol hydrochloride)
2,000 mg/100 mL (20 mg/mL) Ready-to-use Bags
100 mL Bags
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC INJECTION
(esmolol hydrochloride)
100 mg/10 mL (10 mg/mL) Ready-to-use Vials
10 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 10 milligrams/mL (10,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
BREVIBLOC DOUBLE STRENGTH INJECTION
(esmolol hydrochloride)
100 mg/5 mL (20 mg/mL) Ready-to-use Vials
5 mL Vials
Iso-Osmotic Solution of Esmolol Hydrochloride in Sodium Chloride
For Intravenous Use
Can be used for direct intravenous use.
Esmolol Hydrochloride concentration = 20 milligrams/mL (20,000 micrograms/mL)
Single Patient Use Only
No Preservatives Added
DRUG DESCRIPTION



What are the possible side effects of esmolol (Brevibloc)?

Esmolol use has been associated with low blood pressure and other serious side effects.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
Read All Potential Side Effects for Brevibloc »




BREVIBLOC (Esmolol Hydrochloride) is a beta1-selective (cardioselective)
adrenergic receptor blocking agent with a very short duration of action (elimination
half-life is approximately 9 minutes). Esmolol Hydrochloride is:
(±)-Methyl p-[2-hydroxy-3-(isopropylamino) propoxy] hydrocinnamate hydrochloride
and has the following structure:







Esmolol Hydrochloride has the empirical formula C16H26NO4Cl
and a molecular weight of 331.8. It has one asymmetric center and exists as
an enantiomeric pair.
Esmolol Hydrochloride is a white to off-white crystalline powder. It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol. Its partition coefficient (octanol/water) at pH 7.0 is 0.42 compared to 17.0 for propranolol.
Brevibloc Premixed Injection
BREVIBLOC PREMIXED INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
2500 mg, 250 mL Single Use Premixed Bag - Each mL contains 10 mg Esmolol
Hydrochloride, 5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered
with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid,
USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary, to adjust
pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The 250 mL bag
is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia bag is
manufactured from a specially designed multilayer plastic (PL 2408). Solutions
in contact with the plastic container leach out certain chemical compounds from
the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
2000 mg, 100 mL Single Use Premixed Bag DOUBLE STRENGTH - Each mL contains
20 mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary,
to adjust pH to 5.0 (4.5-5.5). The calculated osmolarity is 312 mOsmol/L. The
100 mL bag is a non-latex, non-PVC IntraVia bag with dual PVC ports. The IntraVia
bag is manufactured from a specially designed multilayer plastic (PL 2408).
Solutions in contact with the plastic container leach out certain chemical compounds
from the plastic in very small amounts; however, biological testing was supportive
of the safety of the plastic container materials. See DOSAGE
AND ADMINISTRATION, Directions for Use of the Premixed Bag for additional
information.
Brevibloc Injection
BREVIBLOC INJECTION is a clear, colorless to light yellow, sterile, nonpyrogenic, iso-osmotic solution of esmolol hydrochloride in sodium chloride.
100 mg, 10 mL Single Dose Vial - Each mL contains 10 mg Esmolol Hydrochloride,
5.9 mg Sodium Chloride, USP and Water for Injection, USP; buffered with 2.8
mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial Acetic Acid, USP. Sodium
Hydroxide and/or Hydrochloric Acid added, as necessary to adjust pH to 5.0 (4.5-5.5).
100 mg, 5 mL DOUBLE STRENGTH Single Dose Vial - Each mL contains 20
mg Esmolol Hydrochloride, 4.1 mg Sodium Chloride, USP and Water for Injection,
USP; buffered with 2.8 mg Sodium Acetate Trihydrate, USP and 0.546 mg Glacial
Acetic Acid, USP. Sodium Hydroxide and/or Hydrochloric Acid added, as necessary
to adjust pH to 5.0 (4.5-5.5).Last reviewed on RxList: 12/3/2007





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Other reviews about Brevibloc on web:

Learn about the prescription medication Brevibloc (Esmolol), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Brevibloc (Esmolol) Drug Information: Uses, Side Effects, Drug ...


All about Brevibloc. View complete and up to date Brevibloc information - part of the Drugs.com trusted medication database. Brevibloc Facts and Comparisons at Drugs.com


Brevibloc Premixed Injection (esmolol HCI in NaCl) is for the treatment of SVT, intraoperative and postoperative tachycardia and/or hypertension. Brevibloc


Accurate, FDA approved Brevibloc information for healthcare professionals and patients - brought to you by Drugs.com. Brevibloc Official FDA information, side effects and uses.


Esmolol (trade name Brevibloc) is a cardioselective beta 1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane ... Esmolol - Wikipedia, the free encyclopedia


BREVIBLOC SUMMARY BREVIBLOC (Esmolol Hydrochloride) is a beta 1-selective (cardioselective) adrenergic receptor blocking agent with a very short duration of action ... Brevibloc (Esmolol) - Drug Info, Side Effects, Research, Clinical ...


Consumer information about the medication ESMOLOL HYDROCHLORIDE - INJECTION (Brevibloc), includes side effects, drug interactions, recommended dosages, and storage information. ESMOLOL HYDROCHLORIDE - INJECTION (Brevibloc) side effects ...


Buy Brevibloc (Esmolol Hcl) from our Canadian Online Pharmacy by calling 1-877-888-3562. Fully licensed, fast delivery, free doctor consultation provided. Buy Brevibloc (Esmolol Hcl) Online Now


brevibloc: noun: intravenous beta blocker (trade name Brevibloc) that acts for only a short time; used primarily for cardiac arrhythmias [syn: esmolol] Brevibloc | Define Brevibloc at Dictionary.com


Thesaurus Legend: Synonyms Related Words Antonyms. Noun: 1. Brevibloc - intravenous beta blocker (trade name Brevibloc) that acts for only a short time; used primarily for cardiac ... Brevibloc - definition of Brevibloc by the Free Online Dictionary ...





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