Reviews Bortezomib


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Velcade Drug Description
VELCADE®
(bortezomib) for Injection
DRUG DESCRIPTION



What are the possible side effects of bortezomib (Velcade)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
feeling like you might pass out;
dry cough and trouble breathing;
severe headache, vision problems, confusion, and/or seizure...
Read All Potential Side Effects for Velcade »




VELCADE® (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Each single use vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. Inactive ingredient: 35 mg mannitol, USP.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine.
The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid.
Bortezomib has the following chemical structure:








The molecular weight is 384.24. The molecular formula is C19H25BN4O4.
The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3
to 3.8 mg/mL in a pH range of 2 to 6.5.
Last reviewed on RxList: 1/26/2010




Velcade Drug Description
VELCADE®
(bortezomib) for Injection
DRUG DESCRIPTION



What are the possible side effects of bortezomib (Velcade)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
feeling like you might pass out;
dry cough and trouble breathing;
severe headache, vision problems, confusion, and/or seizure...
Read All Potential Side Effects for Velcade »




VELCADE® (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Each single use vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. Inactive ingredient: 35 mg mannitol, USP.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine.
The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid.
Bortezomib has the following chemical structure:








The molecular weight is 384.24. The molecular formula is C19H25BN4O4.
The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3
to 3.8 mg/mL in a pH range of 2 to 6.5.
Last reviewed on RxList: 1/26/2010




Velcade Drug Description
VELCADE®
(bortezomib) for Injection
DRUG DESCRIPTION



What are the possible side effects of bortezomib (Velcade)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
feeling like you might pass out;
dry cough and trouble breathing;
severe headache, vision problems, confusion, and/or seizure...
Read All Potential Side Effects for Velcade »




VELCADE® (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Each single use vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. Inactive ingredient: 35 mg mannitol, USP.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine.
The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid.
Bortezomib has the following chemical structure:








The molecular weight is 384.24. The molecular formula is C19H25BN4O4.
The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3
to 3.8 mg/mL in a pH range of 2 to 6.5.
Last reviewed on RxList: 1/26/2010




Velcade Drug Description
VELCADE®
(bortezomib) for Injection
DRUG DESCRIPTION



What are the possible side effects of bortezomib (Velcade)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
feeling like you might pass out;
dry cough and trouble breathing;
severe headache, vision problems, confusion, and/or seizure...
Read All Potential Side Effects for Velcade »




VELCADE® (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Each single use vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. Inactive ingredient: 35 mg mannitol, USP.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine.
The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid.
Bortezomib has the following chemical structure:








The molecular weight is 384.24. The molecular formula is C19H25BN4O4.
The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3
to 3.8 mg/mL in a pH range of 2 to 6.5.
Last reviewed on RxList: 1/26/2010




Velcade Drug Description
VELCADE®
(bortezomib) for Injection
DRUG DESCRIPTION



What are the possible side effects of bortezomib (Velcade)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:

new or worsening nerve problems such as numbness, burning, pain, weakness, or tingly feeling;
feeling like you might pass out;
dry cough and trouble breathing;
severe headache, vision problems, confusion, and/or seizure...
Read All Potential Side Effects for Velcade »




VELCADE® (bortezomib) for Injection is an antineoplastic agent available for intravenous injection (IV) use only. Each single use vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. Inactive ingredient: 35 mg mannitol, USP.
Bortezomib is a modified dipeptidyl boronic acid. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine.
The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid.
Bortezomib has the following chemical structure:








The molecular weight is 384.24. The molecular formula is C19H25BN4O4.
The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3
to 3.8 mg/mL in a pH range of 2 to 6.5.
Last reviewed on RxList: 1/26/2010





Other reviews about Bortezomib on wordpress

Bortezomib may help mesothelioma patients
  by John Caron
Malignant pleural mesothelioma is resistant to chemotherapy. Bortezomib is an FDA-approved proteasome inhibitor that is currently being studied for its effects on various types of cancer, but has […]


Mesothelioma science news
  by John Caron
San Pedro, CA - October 9, 2007 1. Restricted field radiation therapy provides an improved method for radiating a complex target after extrapleural pneumonectomy. Link here. 2. First exposure […]


Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma
  by journaldokter
Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma Jesús F. San Miguel, M.D., Ph.D., Rudolf Schlag, M.D., Nuriet K. Khuageva, M.D., Ph.D., Meletios A. Dimopoulos, M.D., […]


Treatments for multiple myeloma? Take it easy with green tea
  by Ed Darrell
Contrary to Tinfoil Hat Philosophy, researchers are rather intensely studying green tea and potential good health effects it may have. The bad news is that an early study shows […]


FDA MedWatch - December 2009 Drug Safety Labeling Changes
  by irbtipoftheweek
The MedWatch December 2009 Drug Safety Labeling Changes posting includes 28 drug products with safety labeling changes to the following sections: BOXED WARNING, CONTRAINDICATIONS, WARNINGS, PRECAUTIONS, ADVERSE REACTIONS, […]


FDA MedWatch - Velcade (bortezomib): Starting Dose Adjustments for Patients with Hepatic Impairment
  by irbtipoftheweek
Takeda Oncology and FDA notified healthcare professionals about revisions to the Prescribing Information for Velcade, section 2.5, pertaining to patients with hepatic impairment at the start of Velcade […]


Bortezomib
  by likui0632
Bortezomib Name: Bortezomib Synonyms: [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid; Velcade; DPBA Molecular Structure:    Molecular Formula: C19H25BN4O4 Molecular Weight: 384.24 CAS Registry Number: 179324-69-7  Bortezomib (INN, originally codenamed PS-341; marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome […]


Importance of Achieving a Complete Response in Multiple Myeloma, and the Impact of Novel Agents
  by zedie
Corresponding author: Asher A. Chanan-Khan, MD, Department of Medicine, Roswell Park Cancer Institute, Elm & Carlton St, Buffalo, NY, 14263; e-mail:  The goal of treatment […]


Cancer drug & MS
  by sofija
An article published July 2nd, on the Medical News Today website reports on yet another cancer drug that shows promise for the treatment of a wide range of […]


Evaluation of Blood Purification and Bortezomib Plus Dexamethasone Therapy for the Treatment of Acute Renal Failure Due to Myeloma Cast Nephropathy Therapeutic Apheresis and Dialysis
  by zedie
Hasegawa M et al. – Aggressive removal of circulating free light chains (FLC) by blood purification accompanied by chemotherapy is a promising approach for the treatment […]



Other reviews about Bortezomib on web:

Bortezomib (INN, originally codenamed PS-341; marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome inhibitor to be tested in humans. Bortezomib - Wikipedia, the free encyclopedia


Proteasome inhibitor drug for treating cancer. ... Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome. Bortezomib - Proteasome inhibitor for cancer


Bortezomib Key Terms: Antineoplastic , Enzyme , Peripheral neuropathy , Saline . Definition Bortezomib is an man-made antineoplastic drug used to Bortezomib: Information from Answers.com


This page contains brief information about bortezomib and a collection of links to more information about the use of this drug, related news and research results, and ongoing ... Bortezomib - National Cancer Institute


All about Bortezomib. View complete and up to date Bortezomib information - part of the Drugs.com trusted medication database. Bortezomib Facts and Comparisons at Drugs.com


Physician reviewed bortezomib patient information - includes bortezomib description, dosage and directions. bortezomib medical facts from Drugs.com


Learn more about Bortezomib. Find the Web's best health guides, medical reports, news, videos and tools for Bortezomib. Share Bortezomib experiences and get advice from experts. Bortezomib Overview - References, Advice, News, Videos, Coping ...


Learn about the prescription medication Velcade (Bortezomib), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Velcade (Bortezomib) Drug Information: Uses, Side Effects, Drug ...


Provides information on usage, precautions, side effects and brand names when available. Data provided by government agencies and health-related organizations Bortezomib: MedlinePlus Drug Information


The search textbox has an autosuggest feature. When you enter three or more characters, a list of up to 10 suggestions will popup under the ... Definition of bortezomib - National Cancer Institute Drug Dictionary





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